• 제목/요약/키워드: LAPS

검색결과 63건 처리시간 0.028초

페니실린 농도 검출을 위한 광지시형 전위차 센서의 제작 및 감응특성 (Fabrication and Response Characteristics of the Light Addressable Potentiometric Sensor for Detecting the Penicillin Concentration)

  • 장수원;정영희;박진호;김재호;권대혁;이승하;강신원
    • 센서학회지
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    • 제13권5호
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    • pp.356-362
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    • 2004
  • In this study, we developed the measuring system based on light addressable potentiometric sensor for the quantitative analysis of penicillin that is very important element in medicine and pharmacy, clinic. It is investigated the response characteristics by enzyme reaction with penicillinase. First, the surface pre-treatment process of the $Si_{3}N_{4}$ was established. The coupling agent was made using self assembled monolayer method and it was confirmed the immobilization process by AFM. Also, as the measuring system, potentiostat, signal processing part etc. was made by Lab VIEW software, it was reduced detecting time as well as simplifying the system. Fabricated device was shown excellent pH response characteristics, 57 mV/ pH in the range of pH $2{\sim}11$. The response characteristics was 60 mV/decade in the range of $0.1{\sim}10{\;}mM$.

자궁절제술 후 신체적 불편감과 성생활 양상 (Physical Discomforts and Sexual Life Pattern of Women with Hysterectomy)

  • 안영란;박영숙
    • 여성건강간호학회지
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    • 제6권2호
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    • pp.218-233
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    • 2000
  • The purposes of this study were to investigate the physical discomforts and sexual life pattern and to identify the relation between the physical discomforts and the satisfaction of sexual life in women with hysterectomy. The subject were 301 women who lived with their spouses from 3 months to 2 years after hysterectomy in S. University Hospital. The data were collected using a self-reported questionnaire by mail, which composed of 25 items of physical discomforts, restarting time and frequency of sexual intercourse, and 10 items of sexual satisfaction, The results were as follows: 1) The mean score of physical discomforts was 13.22 and range of score was 0-45. 1.7% of 301 women had no physical discomforts and 12.0% of them complained of severe physical discomforts such as fatigue, lumbago and pain of extremities. 2) The women with hysterectomy complained of fatigue(76.1%), lumbago(68.8%), pain of extremities(63.5%), weight gain(55.5%), vaginal dryness(50.8%) and symptom of estrogen deficiency such as perspiration (47.5%), flush(41.2%) and palpitation (38.5%). As unusual symptom, numbness of thigh (20.3%) and acne(16.3%) were identified. 3) There was no significant difference between the degree of physical discomforts and the laps of time after hysterectomy. But the score of physical discomforts was lower in women with vaginal hysterectomy than in women with abdominal hysterectomy. 4) The mean score of sexual satisfaction was 33.11 and range of score was 10-50. There was no significant difference between the degree of sexual satisfaction and the lapse of time after hysterectomy. 83.8% of women had not change of sexual life satisfaction after hysterectomy. The women restarted sexual intercourse in average 2.57 months after hysterectomy. 5) There was a negative correlation between the physical discomforts and the sexual satisfaction. In conclusion, nurses should make the discharge educational program of the physical discomforts and the sexual pattern for women with hysterectomy in hospital.

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살균제의 벼 육묘상 처리에 의한 도열병 방제 효과 (The Effect of Fungicides against Rice Blast by the Nursery Treatment at Rice Seedling)

  • 강범관;민지영;김윤식;;정해연;조인준;김흥태
    • 식물병연구
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    • 제10권1호
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    • pp.69-72
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    • 2004
  • Carbosulfan과 합제로 개발한 isoprothiolane과 tricyclazole, 그리고 probenazole을 벼 육묘상자에 처리하고, 처리 당일에 본답에 이앙한 후, 잎도열병과 목도열병에 대한 방제 효과를 조사하였다. 세 가지의 살균제는 모두 이앙하고 3개월 후까지도 잎도열병을 방제할 수 있었다. 특히 tricyclazole 합제의 경우에는 시간이 경과하면서 그 효과가 더 상승하였으며, 9월 6일 조사 때에 85.5%의 잎도열병 방제 효과를 보였다. 목도열병에 대한 효과는 probenazole이 가장 우수하였는데, 10월 14일에 조사한 probenazole 처리구의 목도열병 이병수율은 6.9%로 78.7%의 무처리구에 비하여 91.2%의 방제 효과를 보였다. Isoprothiolane과 tricyclazole 합제는 잎도열병보다 목도열병에 대한 방제 효과가 저조하였으며, 두 처리구는 각각 47.5%와 61.1%의 효과를 보였다. 이상의 결과처럼 침투이행효과가 우수한 살균제가 벼의 육모상 처리제로 개발이 가능해진다면 포장에서의 도열병 방제가 효과적이고 간편하게 수행될 수 있을 것이다.

열간단조 플랜지 금형의 형상에 따른 충전 및 응력해석 (Analysis of Filling and Stresses in the Hot Forging Process Depending on Flange Die Shapes)

  • 김준형;김철
    • 대한기계학회논문집A
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    • 제34권4호
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    • pp.423-430
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    • 2010
  • 표면의 균열, 겹침결함, 금형의 코너반경이 작아 재료의 유동성이 낮을 때 발생하는 콜드셧, 부분충진등의 단조결함이 없는 자동차용 단조 플랜지를 생산하기 위해서 열전달, 단류선 흐름, 응력분포를 고려하여 형단조 공정과 금형에 대한 해석을 수행하였다. 축박기(up-set) 단조, 예비성형, 최종성형, 단조압력으로 구성된 단조과정은 유한요소법으로 해석되었다. 예비성형과 상하 금형의 높이비율이 단조공정과 금형에 미치는 영향을 평가하여 예비금형의 각 $10^{\circ}$와 최종 금형의 상하비율 1.5:1이 단조결함이 없는 결과를 나타내었다. 이를 반영한 새로 설계된 금형은 재료강도, 완전충진, 하중한계 13,000 KN 이라는 공정변수를 모두 만족시켰다. 이론 입증을 위해서 개선된 금형과 플랜지가 제작되었으며, 단조결함이 발견되지 않았다.

『황제내경(黃帝內經)』의 침구법(鍼灸法) 연구 - 시간(時間) 개념을 중심으로 - (A Study on the Acupuncture & Moxibustion of Huangdineijing - focused on Concept of Time -)

  • 류정아
    • 대한한의학원전학회지
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    • 제29권3호
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    • pp.57-74
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    • 2016
  • Subject : Treatment of acupuncture & moxibustion in Huangdineijing Objectives : Discover the principles and substances of acupuncture & moxibustion treatment of Huangdineijing Methods : The author reviewed the Huangdineijing: Suwen, Lingshu to gain a realistic sense of the facts and the medical book's contents that deal with the practices of acupuncture & moxibustion treatment for clinical praxis. Conclusions : 1. The acupuncture & moxibustion of Huangdineijing can be defined as follows. A treatment for correcting of meridian's drift by proper selection of surgical site, using suitable implementation and appropriate manipulation skill from a correct judgement of meridian's flowing through sensing the pulse for diagnosis when the meridian's flowing which come and go constantly driven by the tidal order of defensive Qi tactually appeared hard or soft caused by diseases, thus bring out the soft & gradual 50 laps circulation of nutrient Qi moderately driven by defensive Qi. 2. Today's acupuncture & moxibustion treatments greatly differ from those of Huangdineijing in that we do not know the substance of that treatment which is correcting of meridian's drift and do not obligatorily carry out feeling of the pulse for diagnosis which is a measure & judgement of meridian's flowing against a preliminary treatment in parallel with treatment so reduce use and power of that treatment. 3. I could form a list of general principle from the substances of acupuncture & moxibustion of Huangdineijing like as the flowing or fate of meridian Qi(tidally going in order of defensive Qi and nutrient Qi), deficiency or excess of Meridian flowing, comparing diagnosis before and after treatment, bring out the soft & gradual Qi. That was imposing "the concept of time" on recognition and treatment to human body.

미세조류, Skeletonema costatum의 성장에 미치는 유기주석 화합물들의 급성 및 만성 독성효과 (The Acute and Chronic Toxicity Effects of Triorganotins on the Growth of Microalgae, Skeletonema costatum)

  • 함경훈;김무상;이형호
    • 한국수산과학회지
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    • 제35권5호
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    • pp.534-541
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    • 2002
  • 살충제, 살균제 그리고 antifouling 약품 등으로써의 triorganotin의 사용은 지난 30년간 놀라울 정도로 증가해왔다. 이 보고에서는 미세조류 Skeletonema costatum의 성장에 미치는 여러 triorganotin (TBTO, TBTF, CTPT, TBTCI)들의 급성 및 만성 독성효과를 조사하기 위하여, 단기 및 장기 독성실험을 각각 수행하였다. 단기 독성실험에서, 여러 triorganotin들의 S. costatum에 대한 성장저해 효과는 처리농도에 비례하여 증가하였으며, 이 성장저해는 시간 경과에 따라 회복되었다. 그러나 여러 triorganotin의 독성의 성장저해 효과가 접종한 S. costatum의 세포밀도에 따라 다름을 보였다. 접종 세포농도가 높을수록 triorganotin의 독성효과는 감소하였다. 이러한 결과는 triorganotin의 S. costatum에 의한 분해에 의한 것이라고 판단된다. 장기 독성실험에서는 단기 독성실험에서와는 달리 1 $\mu$g/L의 triorganotin의 농도에서도 S. costatum이 사멸하였다. 이러한 사실은 낮은 밀도의 식물성 플랑크톤이 존재하는 해수에서 지속적으로 존재하는 triorganotin의 독성은 훨씬 더 강하게 나타날 수 있음을 보여준다.

구기자 추출액 첨가가 나박김치의 발효 중 이화학적 특성에 미치는 영향 (Effect of Kugija (Lycium chinense Miller) Extract on the Physicochemical Properties of Nabak kimchi during Fermentation)

  • 김미정;정광자;장명숙
    • 한국식품조리과학회지
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    • 제22권6호통권96호
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    • pp.832-839
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    • 2006
  • Kugija was added to Nabak kimchi to improve the quality and preservation and the optimum addition level was assessed. Kugija extract was prepared by boiling kugija fruits, at different ratios (0, 1, 3, 5, 7%; w/v) in water for 30 minutes. The changes in the physicochemical properties of the Nabak kimchi were measured during storage for 25 days at 10?, and compared to a control (without kugija). The pH was decreased in all treatments. Following the fermentation of Nabak kimchi, the total acidity values were inversely proportional the pH changes according to the nature of mutual dependence. However, in short term, during the initial 7 days of fermentation, the total acidity values decreased with increasing concentrations of kugija extract, whereas the trend was reversed after day 10. Total vitamin C content was directly proportional to the concentration of kugija extract and was decreased with the laps of fermentation. Up to day 25, 7% treatment showed the highest vitamin C content, but at 25 days 1% and 3% treatments ranked the first. The mont of reducing sugar was proportional to the concentration of kugija extract however, the difference of values between all treatments became almost indiscernible after day 25. Turbidity values were generally increased in all samples during fermentation period, although only to a limited extent. The lowest turbidity was shown at 3% treatment up to day 16. Total color difference values were increased up to day 16, but then decreased. The optimum level of kugija extract in Nabak kimchi, as determined through these experiments, was between 1 to 3% per added water content, and was preferably 3% for color and fermentation-retarding effect of the product. Kugija extract could be applied for improving the quality and preservation of traditionally prepared Nabak kimchi.

남북상사중재에 있어 중재인 선정방식에 관한 연구 (A Study on Improving a Method of the Appointment of Arbitrators in Inter-Korean Commercial Arbitration)

  • 이주원
    • 한국중재학회지:중재연구
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    • 제18권1호
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    • pp.147-165
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    • 2008
  • Appointment of arbitrators is very important in arbitration. As it has been a long laps since Korean peninsula was devided into two parts, South and North, it has come to be too much gaps between South and North in the law, social system, commercial practice and etc.. South Korea is familar to international commercial practice and capitalistic legal system generalized internationally in modern times. On the other hand as North Korea was closed society for a long time, they are not familar to international commercial practice and market economy. In this connection, commercial disputes arising from the transactions between South and North will occur frequently and it will be very difficult to select governing law or commercial practice referred to the disputes. Under the circumstances, when and if an arbitrator from South or North will be appointed as presiding arbitrator in the tribunal composed by three arbitrators, the part from which the presiding arbitrator come will be a majority, and it will be advantageous to the parties came from the part of which the presiding arbitrator come from. Such being the case, sole arbitrator or presiding arbitrator needs to be appointed among foreigner. Otherwise I recommend the tribunal composed by two arbitrators and umpire system. As to arbitrator's fee, as there is a big gap in its economic aspects between South and North, I supposed to need establishing the fund made by corporation with South and North in order to compensate arbitrators from South or abroad for their fee. Finally it is more important to prevent disputes arising from transactions between South and North. In order to prevent the disputes, education for North Korean about international commercial practice and skill to make a contract of international sale of goods and investment are needed.

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인삼추출물의 장기적인 급여가 흰쥐의 혈중 CO-Hb 제거에 미치는 영향 (Effect of Chronic Treatment of Ginseng Extract on the Clearance of Blood Carbon Monoxide in Rat)

  • Lee, Young-Gu;Sohn, Hyung-Ok;Lim, Heung-Bin;Lee, Dong-Wook
    • Journal of Ginseng Research
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    • 제19권3호
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    • pp.225-230
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    • 1995
  • The effect of long-term ginseng (Panax ginseng C.A. Meyer) administration on the clearance of carboxyhemoglobin (CO-Hb) and the property of blood gases was investigated in rats. Rats were received ginseng water extract (0.025% in drinking water) for 42 weeks starting at the age of 6 weeks. They were exposed to the diluted mainstream smoke generated from 15 filter cigarettes for 20 min in a round polycarbonate chamber (D37 cmXH13 cm). Under this condition, the mean CO-Hb content of control and the ginseng-treated rats immediately after the exposure was nearly the same as 13.8$\pm$2.9 f) and 13.9$\pm$1.6%, respectively. However, CO-Hb was more rapidly removed from blood in the ginseng treated rats than in untreatEd control with the laps of time, namely, its biological half life In the former was 36.9$\pm$1.5 min and in the latter was 56.9$\pm$13.2 min. Although long-term ginseng treatment did not affect the content of hemoglobin and blood pH of rats, it slightly increased blood oxygen content and its partial pressure value, and decreased levels of carbon dioxide and bicarbonate. These results suggest that long-term administration of rats with ginseng extract accelerate the elimination of CO from the blood. This effect seems to be related to the enhancement of oxygen consumption of the rat by a certain action of ginseng components as previously reported.

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나노결정질 다이아몬드가 코팅된 SiC 마모시험기 볼 (Nanocrystalline Diamond Coated SiC Balls in Tribometer)

  • 임종환;강찬형
    • 한국표면공학회지
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    • 제47권5호
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    • pp.263-268
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    • 2014
  • Nanocrystalline diamond(NCD) coated SiC balls were applied in a ball-on-disk tribometer. After seeding in an ultrasonic bath containing nanometer diamond powders, $2.2{\mu}m$ thick NCD films were deposited on sintered 3 mm diameter SiC balls at $600^{\circ}C$ in a 2.45 GHz microwave plasma CVD system. Bare $ZrO_2$ and SiC balls were prepared for comparison as test balls. Tribology tests were performed in air with pairs of three different balls and mirror polished steel(SKH51) disk. The wear tracks on balls and disks were examined by optical microscope and alpha step profiler. Under the load of 3 N, the friction coefficients of steel against $ZrO_2$, SiC and NCD-coated balls were between 0.4 and 0.8. After a few thousands sliding laps, the friction coefficient of NCD-coated balls dropped from 0.45 to below 0.1 and maintained thereafter. Under a higher load of 10 N or 20 N with a long sliding distance of 2 km, $ZrO_2$ and SiC balls exhibited the similar friction coefficients as above. The friction coefficient of NCD-coated balls was less than 0.1 from the beginning and increased to above 0.1 steadily or with some fluctuations as sliding distance increased. NCD coating layers were found worn out after long duration and/or high load sliding test, which resulted in the friction coefficient higher than 0.1.