• Title/Summary/Keyword: LAPS

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Fabrication and Response Characteristics of the Light Addressable Potentiometric Sensor for Detecting the Penicillin Concentration (페니실린 농도 검출을 위한 광지시형 전위차 센서의 제작 및 감응특성)

  • Jang, Su-Won;Jung, Young-Hee;Park, Jin-Ho;Kim, Jea-Ho;Kwon, Dae-Hyuk;Lee, Seung-Ha;Kang, Shin-Won
    • Journal of Sensor Science and Technology
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    • v.13 no.5
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    • pp.356-362
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    • 2004
  • In this study, we developed the measuring system based on light addressable potentiometric sensor for the quantitative analysis of penicillin that is very important element in medicine and pharmacy, clinic. It is investigated the response characteristics by enzyme reaction with penicillinase. First, the surface pre-treatment process of the $Si_{3}N_{4}$ was established. The coupling agent was made using self assembled monolayer method and it was confirmed the immobilization process by AFM. Also, as the measuring system, potentiostat, signal processing part etc. was made by Lab VIEW software, it was reduced detecting time as well as simplifying the system. Fabricated device was shown excellent pH response characteristics, 57 mV/ pH in the range of pH $2{\sim}11$. The response characteristics was 60 mV/decade in the range of $0.1{\sim}10{\;}mM$.

Physical Discomforts and Sexual Life Pattern of Women with Hysterectomy (자궁절제술 후 신체적 불편감과 성생활 양상)

  • Ahn, Young-Lan;Park, Young-Sook
    • Women's Health Nursing
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    • v.6 no.2
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    • pp.218-233
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    • 2000
  • The purposes of this study were to investigate the physical discomforts and sexual life pattern and to identify the relation between the physical discomforts and the satisfaction of sexual life in women with hysterectomy. The subject were 301 women who lived with their spouses from 3 months to 2 years after hysterectomy in S. University Hospital. The data were collected using a self-reported questionnaire by mail, which composed of 25 items of physical discomforts, restarting time and frequency of sexual intercourse, and 10 items of sexual satisfaction, The results were as follows: 1) The mean score of physical discomforts was 13.22 and range of score was 0-45. 1.7% of 301 women had no physical discomforts and 12.0% of them complained of severe physical discomforts such as fatigue, lumbago and pain of extremities. 2) The women with hysterectomy complained of fatigue(76.1%), lumbago(68.8%), pain of extremities(63.5%), weight gain(55.5%), vaginal dryness(50.8%) and symptom of estrogen deficiency such as perspiration (47.5%), flush(41.2%) and palpitation (38.5%). As unusual symptom, numbness of thigh (20.3%) and acne(16.3%) were identified. 3) There was no significant difference between the degree of physical discomforts and the laps of time after hysterectomy. But the score of physical discomforts was lower in women with vaginal hysterectomy than in women with abdominal hysterectomy. 4) The mean score of sexual satisfaction was 33.11 and range of score was 10-50. There was no significant difference between the degree of sexual satisfaction and the lapse of time after hysterectomy. 83.8% of women had not change of sexual life satisfaction after hysterectomy. The women restarted sexual intercourse in average 2.57 months after hysterectomy. 5) There was a negative correlation between the physical discomforts and the sexual satisfaction. In conclusion, nurses should make the discharge educational program of the physical discomforts and the sexual pattern for women with hysterectomy in hospital.

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The Effect of Fungicides against Rice Blast by the Nursery Treatment at Rice Seedling (살균제의 벼 육묘상 처리에 의한 도열병 방제 효과)

  • Kang, Beum-Kwan;Min, Ji-Young;Kim, Yun-Sik;Van Bach, Nguyen;Jung, Hae-Yeon;Cho, In-Joon;Kim, Heung-Tae
    • Research in Plant Disease
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    • v.10 no.1
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    • pp.69-72
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    • 2004
  • The control activity of isoprothiolane and tricyclazole mixed with carbosulfan, and probenazole by the nursery treatment was performed against rice leaf and neck blast caused by Magnaporthe grisea. In the paddy field, three fungicides showed good activities against leaf blast 3 months after nursery treatment. Especially the activity of tricyclazole against leaf blast gradually increased by the laps of time to 85.5%, which was assessed at 6 September,2003. Although the control value of isoprotholane and tricyclazole mixed with carbosulfan against neck blast was 47.5% and 61.1%, respectively, probenazole showed a very high activity against not only leaf blast but also neck blast, of which that was 91.2%. No phytotoxicity was observed in all the treatments after transplanting rice seedling in the paddy field. Based on these results, three systemic fungicides tested in this study showed such a good potential that they might be used to formulate the nursery treating granule.

Analysis of Filling and Stresses in the Hot Forging Process Depending on Flange Die Shapes (열간단조 플랜지 금형의 형상에 따른 충전 및 응력해석)

  • Kim, Jun-Hyoung;Kim, Cheol
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.4
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    • pp.423-430
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    • 2010
  • Hot closed-forging process and the die used for forming an automotive flange were analyzed from the viewpoints of heat transfer, grain-flow lines, and stresses to obtain a forged product without defects such as surface cracks, laps, cold shots, and partial filling. The forging process including up-set, pre-forging, final forging and pressing forces was investigated using finite element analysis. The influence of the preform die and the ratio of the heights of the upper die to lower die on the forging process and die were investigated and a die shape ($10^{\circ}$ for the preform die, and 1.5:1 ratio for the final die) suitable to achieve successful forging was determined on the basis of a parametric study. All parametric design requirements such as strength, full filling, and a load limit of 13,000 KN were satisfied for this newly developed flange die. New dies and flanges were fabricated and investigated. Defects such as partial filling and surface cracks were not observed.

A Study on the Acupuncture & Moxibustion of Huangdineijing - focused on Concept of Time - (『황제내경(黃帝內經)』의 침구법(鍼灸法) 연구 - 시간(時間) 개념을 중심으로 -)

  • Lyu, Jeong-ah
    • Journal of Korean Medical classics
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    • v.29 no.3
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    • pp.57-74
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    • 2016
  • Subject : Treatment of acupuncture & moxibustion in Huangdineijing Objectives : Discover the principles and substances of acupuncture & moxibustion treatment of Huangdineijing Methods : The author reviewed the Huangdineijing: Suwen, Lingshu to gain a realistic sense of the facts and the medical book's contents that deal with the practices of acupuncture & moxibustion treatment for clinical praxis. Conclusions : 1. The acupuncture & moxibustion of Huangdineijing can be defined as follows. A treatment for correcting of meridian's drift by proper selection of surgical site, using suitable implementation and appropriate manipulation skill from a correct judgement of meridian's flowing through sensing the pulse for diagnosis when the meridian's flowing which come and go constantly driven by the tidal order of defensive Qi tactually appeared hard or soft caused by diseases, thus bring out the soft & gradual 50 laps circulation of nutrient Qi moderately driven by defensive Qi. 2. Today's acupuncture & moxibustion treatments greatly differ from those of Huangdineijing in that we do not know the substance of that treatment which is correcting of meridian's drift and do not obligatorily carry out feeling of the pulse for diagnosis which is a measure & judgement of meridian's flowing against a preliminary treatment in parallel with treatment so reduce use and power of that treatment. 3. I could form a list of general principle from the substances of acupuncture & moxibustion of Huangdineijing like as the flowing or fate of meridian Qi(tidally going in order of defensive Qi and nutrient Qi), deficiency or excess of Meridian flowing, comparing diagnosis before and after treatment, bring out the soft & gradual Qi. That was imposing "the concept of time" on recognition and treatment to human body.

The Acute and Chronic Toxicity Effects of Triorganotins on the Growth of Microalgae, Skeletonema costatum (미세조류, Skeletonema costatum의 성장에 미치는 유기주석 화합물들의 급성 및 만성 독성효과)

  • Ham Kyung Hoon;Kim Moo Sang;Lee Hyung Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.35 no.5
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    • pp.534-541
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    • 2002
  • The use of triorganotins as insecticides, bacteriocides, and antifouling agents has increased dramatically over the past 30 years, In this paper, to evaluate the acute and chronic toxicity effects of various triorganotins (TBTO, TBTE, CTPT, TBTCI) on the growth of microalgae, Skeletonema costatum, we carried out the short term and long term experiments, respectively. In the short-term experiments, the growth of S. costatum was inhibited by the various triorganotins in the dose dependent manners, but recovered by the time laps. The growth inhibition of triorganotins were decreased in the groups with higher initial cell density. These data were resulted from the dilution effect and the biodegradation of triorganotins by the microalgae. In the long-term experiments, S. costatum died completely at the 1 $\mu$g/L of TBTP and CTPT, but didn't in short-term experiments. The facts suggest that the toxicity of the chronic exposure of triorganotins should be increased in the natural sea water with low phytoplankton density.

Effect of Kugija (Lycium chinense Miller) Extract on the Physicochemical Properties of Nabak kimchi during Fermentation (구기자 추출액 첨가가 나박김치의 발효 중 이화학적 특성에 미치는 영향)

  • Kim, Mi-Jung;Chung, Kwang-Ja;Jang, Myung-Sook
    • Korean journal of food and cookery science
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    • v.22 no.6 s.96
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    • pp.832-839
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    • 2006
  • Kugija was added to Nabak kimchi to improve the quality and preservation and the optimum addition level was assessed. Kugija extract was prepared by boiling kugija fruits, at different ratios (0, 1, 3, 5, 7%; w/v) in water for 30 minutes. The changes in the physicochemical properties of the Nabak kimchi were measured during storage for 25 days at 10?, and compared to a control (without kugija). The pH was decreased in all treatments. Following the fermentation of Nabak kimchi, the total acidity values were inversely proportional the pH changes according to the nature of mutual dependence. However, in short term, during the initial 7 days of fermentation, the total acidity values decreased with increasing concentrations of kugija extract, whereas the trend was reversed after day 10. Total vitamin C content was directly proportional to the concentration of kugija extract and was decreased with the laps of fermentation. Up to day 25, 7% treatment showed the highest vitamin C content, but at 25 days 1% and 3% treatments ranked the first. The mont of reducing sugar was proportional to the concentration of kugija extract however, the difference of values between all treatments became almost indiscernible after day 25. Turbidity values were generally increased in all samples during fermentation period, although only to a limited extent. The lowest turbidity was shown at 3% treatment up to day 16. Total color difference values were increased up to day 16, but then decreased. The optimum level of kugija extract in Nabak kimchi, as determined through these experiments, was between 1 to 3% per added water content, and was preferably 3% for color and fermentation-retarding effect of the product. Kugija extract could be applied for improving the quality and preservation of traditionally prepared Nabak kimchi.

A Study on Improving a Method of the Appointment of Arbitrators in Inter-Korean Commercial Arbitration (남북상사중재에 있어 중재인 선정방식에 관한 연구)

  • Lee, Joo-Won
    • Journal of Arbitration Studies
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    • v.18 no.1
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    • pp.147-165
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    • 2008
  • Appointment of arbitrators is very important in arbitration. As it has been a long laps since Korean peninsula was devided into two parts, South and North, it has come to be too much gaps between South and North in the law, social system, commercial practice and etc.. South Korea is familar to international commercial practice and capitalistic legal system generalized internationally in modern times. On the other hand as North Korea was closed society for a long time, they are not familar to international commercial practice and market economy. In this connection, commercial disputes arising from the transactions between South and North will occur frequently and it will be very difficult to select governing law or commercial practice referred to the disputes. Under the circumstances, when and if an arbitrator from South or North will be appointed as presiding arbitrator in the tribunal composed by three arbitrators, the part from which the presiding arbitrator come will be a majority, and it will be advantageous to the parties came from the part of which the presiding arbitrator come from. Such being the case, sole arbitrator or presiding arbitrator needs to be appointed among foreigner. Otherwise I recommend the tribunal composed by two arbitrators and umpire system. As to arbitrator's fee, as there is a big gap in its economic aspects between South and North, I supposed to need establishing the fund made by corporation with South and North in order to compensate arbitrators from South or abroad for their fee. Finally it is more important to prevent disputes arising from transactions between South and North. In order to prevent the disputes, education for North Korean about international commercial practice and skill to make a contract of international sale of goods and investment are needed.

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Effect of Chronic Treatment of Ginseng Extract on the Clearance of Blood Carbon Monoxide in Rat (인삼추출물의 장기적인 급여가 흰쥐의 혈중 CO-Hb 제거에 미치는 영향)

  • Lee, Young-Gu;Sohn, Hyung-Ok;Lim, Heung-Bin;Lee, Dong-Wook
    • Journal of Ginseng Research
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    • v.19 no.3
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    • pp.225-230
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    • 1995
  • The effect of long-term ginseng (Panax ginseng C.A. Meyer) administration on the clearance of carboxyhemoglobin (CO-Hb) and the property of blood gases was investigated in rats. Rats were received ginseng water extract (0.025% in drinking water) for 42 weeks starting at the age of 6 weeks. They were exposed to the diluted mainstream smoke generated from 15 filter cigarettes for 20 min in a round polycarbonate chamber (D37 cmXH13 cm). Under this condition, the mean CO-Hb content of control and the ginseng-treated rats immediately after the exposure was nearly the same as 13.8$\pm$2.9 f) and 13.9$\pm$1.6%, respectively. However, CO-Hb was more rapidly removed from blood in the ginseng treated rats than in untreatEd control with the laps of time, namely, its biological half life In the former was 36.9$\pm$1.5 min and in the latter was 56.9$\pm$13.2 min. Although long-term ginseng treatment did not affect the content of hemoglobin and blood pH of rats, it slightly increased blood oxygen content and its partial pressure value, and decreased levels of carbon dioxide and bicarbonate. These results suggest that long-term administration of rats with ginseng extract accelerate the elimination of CO from the blood. This effect seems to be related to the enhancement of oxygen consumption of the rat by a certain action of ginseng components as previously reported.

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Nanocrystalline Diamond Coated SiC Balls in Tribometer (나노결정질 다이아몬드가 코팅된 SiC 마모시험기 볼)

  • Im, Jong Hwan;Kang, Chan Hyoung
    • Journal of the Korean institute of surface engineering
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    • v.47 no.5
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    • pp.263-268
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    • 2014
  • Nanocrystalline diamond(NCD) coated SiC balls were applied in a ball-on-disk tribometer. After seeding in an ultrasonic bath containing nanometer diamond powders, $2.2{\mu}m$ thick NCD films were deposited on sintered 3 mm diameter SiC balls at $600^{\circ}C$ in a 2.45 GHz microwave plasma CVD system. Bare $ZrO_2$ and SiC balls were prepared for comparison as test balls. Tribology tests were performed in air with pairs of three different balls and mirror polished steel(SKH51) disk. The wear tracks on balls and disks were examined by optical microscope and alpha step profiler. Under the load of 3 N, the friction coefficients of steel against $ZrO_2$, SiC and NCD-coated balls were between 0.4 and 0.8. After a few thousands sliding laps, the friction coefficient of NCD-coated balls dropped from 0.45 to below 0.1 and maintained thereafter. Under a higher load of 10 N or 20 N with a long sliding distance of 2 km, $ZrO_2$ and SiC balls exhibited the similar friction coefficients as above. The friction coefficient of NCD-coated balls was less than 0.1 from the beginning and increased to above 0.1 steadily or with some fluctuations as sliding distance increased. NCD coating layers were found worn out after long duration and/or high load sliding test, which resulted in the friction coefficient higher than 0.1.