• Asian-Australasian Journal of Animal Sciences
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• v.28 no.8
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• pp.1202-1208
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• 2015

The effects of daily dietary Bacillus subtilis (Bs), and adding L-tryptophan, fructan, or casein to fecal fermentation broths were investigated as means to reduce the production of noxious gas during manure fermentation caused by ammonia, hydrogen sulfide ($H_2S$), and 3-methylindole (skatole). Eighty swine ($50.0{\pm}0.5kg$) were equally apportioned to an experimental group given Bs in daily feed, or a control group without Bs. After 6 weeks, fresh manure was collected from both groups for fermentation studies using a $3{\times}3$ orthogonal array, in which tryptophan, casein, and fructan were added at various concentrations. After fermentation, the ammonia, $H_2S$, L-tryptophan, skatole, and microflora were measured. In both groups, L-tryptophan was the principle additive increasing skatole production, with significant correlation (r = 0.9992). L-tryptophan had no effect on the production of ammonia, $H_2S$, or skatole in animals fed Bs. In both groups, fructan was the principle additive that reduced $H_2S$ production (r = 0.9981). Fructan and Bs significantly interacted in $H_2S$ production (p = 0.014). Casein was the principle additive affecting the concentration of ammonia, only in the control group. Casein and Bs significantly interacted in ammonia production (p = 0.039). The predominant bacteria were Bacillus spp. CWBI B1434 (26%) in the control group, and Streptococcus alactolyticus AF201899 (36%) in the experimental group. In summary, daily dietary Bs reduced ammonia production during fecal fermentation. Lessening L-tryptophan and increasing fructan in the fermentation broth reduced skatole and $H_2S$.

• YAKHAK HOEJI
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• v.56 no.1
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• pp.48-54
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• 2012

Enviromental differences in gentamicin pharmacokinetics by using population pharmacokinetic methods were compared with 20 Korean patients and 24 Korean-American appendicitis patients. Two to six blood specimens were collected from all patients at the following times : just before a regularly scheduled infusion and at 0.5 hour after the end of a 0.5 hour infusion. Nonparametric expected maximum (NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant (K), the slope (KS) of the relationship between K versus creatinine clearance ($C_{cr}$), the apparent volume of distribution (V), the slope (VS) of the relationship between V versus weight, gentamicin clearance (CL) and the slope (CS) of the relationship between CL versus $C_{cr}$ and the V. The output includes two marginal probability density function (PDF), means, medians, modes, variance and CV%. The mean K (KS) were $0.402{\pm}0.129\;h^{-1}(0.00486{\pm}0.00197\;[h{\cdot}ml/min/1.73\;m^2]^{-1})$ and $0.411{\pm}0.135\;h^{-1}(0.00475{\pm}0.00180\;[h{\cdot}ml/min/1.73\;m^2]^{-1})$ for Korean and Korean-American populations, respectively. The mean V (VS) were not different at $14.3{\pm}3.6l(0.241{\pm}0.0511l/kg)$ and $15.1{\pm}3.84l(0.239{\pm}0.0492l/kg)$ for Korean and Korean-American populations, respectively (p>0.2). The mean CL (CS) were $5.68{\pm}1.69l/h(0.0714{\pm}0.0222l/kg[h{\cdot}ml/min/1.73\;m^2])$ and $5.70{\pm}1.77l/h(0.0701{\pm}0.0215l/kg[h{\cdot}ml/min/1.73\;m^2])$ for Korean and Korean-American populations, respectively. There were no enviromental differences in gentamicin pharmacokinetics between Korean and Korean-American appendicitis patients.

• Bulletin of the Korean Mathematical Society
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• v.53 no.1
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• pp.21-28
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• 2016

It is known that no two of the roots of the polynomial equation (1) $$\prod\limits_{l=1}^{n}(x-r_l)+\prod\limits_{l=1}^{n}(x+r_l)=0$$, where 0 < $r_1{\leq}r_2{\leq}{\cdots}{\leq}r_n$, can be equal and all of its roots lie on the imaginary axis. In this paper we show that for 0 < h < $r_k$, the roots of $$(x-r_k+h)\prod\limits_{{l=1}\\{l{\neq}k}}^{n}(x-r_l)+(x+r_k-h)\prod\limits_{{l=1}\\{l{\neq}k}}^{n}(x+r_l)=0$$ and the roots of (1) in the upper half-plane lie alternatively on the imaginary axis.

• Korean Aquaculture
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• v.19 no.1
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• pp.34-42
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• 2007

양식 넙치 및 조피볼락을 이용하여 1시간 동안 포르말린(37% 포름알데히드) 100 mg/l, 300 mg/l 및 500 mg/l의 농도에서 약욕 처리한 후 근육 내에서의 포름알데히드 잔류 농도를 측정하였다. 또한 포르말린 농도 25 mg/l, 50 mg/l, 100 mg/l, 150 mg/l 및 200 mg/l의 에어레이션된 해수와 에어레이션이 공급되지 않은 해수에서의 포름알데히드의 손실율을 측정하였다. 1시간 500 mg/l의 포르말린으로 취급된 어류 근육의 포름알데히드 농도는 약욕(0 h 투여 중지) 후 즉시 분석된 대조구 조직의 포름알데히드 농도보다 유의적으로 높게 나타났다(p<0.05). 그러나 대조구 조직내 포름알데히드 농도는 포르말린에 노출 후 24, 48 및 72시간 지난 후 샘플된 어류조직에서의 농도와 유의적인 차이가 없었다(p>0.05). 25-200 mg/l의 포르말린이 포함된 해수의 포름알데히드는 $8{\sim}19$일 이내에 측정 가능한 아주 낮은 농도($0.05\;{\mu}g/ml$)로 되어지나, 그것의 분해는 에어레이션을 함으로서 $6{\sim}10$일 이내로 빨라졌다. 따라서 본 연구에서 밝혀진 것들은 어류양식산업에 있어서 포르말린의 적정 투여 중지 기간과의 결정에 필요한 자료를 제공한다고 생각된다.

• KSBB Journal
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• v.16 no.4
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• pp.398-402
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• 2001

Enzymatic hydrolysis of agar was carried out continuously to produce agarooligosaccharides by immobilized agarase in Packed-Bed Reactor. The reactor was constructed using a acryl tube with an internal diameter of 10 mm and a useful height of 140 mm. The Packed-Bed Reactor was 11 mL reactor volume as its length : diameter ratio was 14 : 1. The operation condition of reaction was performed with an 1 g/L agar concentration at 40$^{\circ}C$, 10 mM MOPS buffer(pH 7.0) and with the flow rate 3 mL∼48 mL/h at a dilution rate of 1.09∼5.45 h$\^$-1/. The hydrolysis products was identified DP6, DP4 and DP2 by HPLC. The conversion rate of agar was about 80% and amount of total agarooligosaccharide was 0.88 mg/mL at Packed-Bed Reactor.

• Korean Journal of Food Science and Technology
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• v.17 no.6
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• pp.426-430
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• 1985

The effects of temperature on the visual color deterioration of Lithospermi radix were investigated under steady conditions of various pH and temperature. The changes of Hunter L, a, b, and ${\Delta}E$ values related to the color deterioration were sharply increased above $50^{\circ}C$ and the deteriorations were expressed linear relationships with the temperature above $60^{\circ}C$. Linear regression coefficients of Hunter L, a, b values decreased with an increase of heat treatment time, whereas the color difference was increased. The linear regression coefficients of Hunter L, a, b, ${\Delta}E$ values in 66.7% ethanol extract solution of Lithospermi radix for 1 hr were -0.3696, -0.4124, -0.2279, and 0.5983, respectively. Inear regression coefficients in color difference (${\Delta}E$) could be calculated from the coefficients in Hunter L, a, b values. The low pH treatment of extract from pH 6.07 to pH 1.35 led to decrease of Hunter a value and a little increase of Hunter L, b values, but the high pH treatment above pH 6.07 decreased all Hunter values. Particularly, the visual color of the extract of Lithospermiradix was appeared to be faborable at pH 4.0-6.5, which was a bright red color.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.29 no.1
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• pp.29-37
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• 2011

The purpose of this research is to measure Quality of Life indices using Factor Analysis and Principle Component Analysis and to analyze the spatial patterns of Quality of life distribution in the Seoul Metropolitan Area in terms of spatial association using spatial statistics and spatial exploratory technique. In order to check the degree of clustering, this study used spatial autocorrelation indices, global Moran's I index. In addition, local scale analysis was conducted using Moran Scatterplot and Local Moran's I to identify the spatial association pattern and the high Quality of life. The analysis based on global statics showed that, in the Seoul Metropolitan Area, QoL Indices had been distributed with positive spatial association. According to the local spatial statistics, the general tendency of clustering H-H clusters which were mainly concentrated on the Seoul, L-H clusters were concentrated on the Kyunggi-Do and L-L Clusters showed the regional extent of lagging behind. However, in case of H-H, L-H Clusters they had been spread out in the Newtown as population increase.

• Journal of Korean Society of Environmental Engineers
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• v.36 no.1
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• pp.67-73
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• 2014

In this study, the residual heavy metals in the mine tailings, primarily treated by soil washing, were stabilized using phosphate salts. The concentrations of residual contaminants in the washed mine tailings were As (1,861 mg/kg), Cd (20 mg/kg), Cu (56 mg/kg), Pb (2,149 mg/kg), and Zn (633 mg/kg). They were stabilized with $CaHPO_4$, $Ca(H_2PO_4)_2{\cdot}H_2O$, and hydroxyapatite at 0.1 wt%, 1 wt%, and 10 wt% for 1, 3, 5, 7, and 14 days. It was found that 1 wt% $Ca(H_2PO_4)_2{\cdot}H_2O$ was optimum in our experiments, but the stabilization duration did not affect the efficiency. After stabilization with 1 wt% $Ca(H_2PO_4)_2{\cdot}H_2O$ for 1 day, the concentrations of arsenic and heavy metals, As (0.328 mg/L), Cd (0.250 mg/L), Cu (0.143 mg/L), Pb (0.359 mg/L), and Zn (2.622 mg/L), in TCLP leachate were below the RCRA-TCLP limits, which meant the contaminants in the treated mine tailings were stably immobilized.

• Korean Journal of Materials Research
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• v.33 no.4
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• pp.130-134
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• 2023

This study evaluated cell viability and cytokine release in immortalized human oral fibroblasts (hTERT-hNOFs) and keratinocytes (IHOK) exposed to a dental-impregnated gingival retraction cord. To prepare the extracts, dental gingival retraction cords impregnated with aluminum chloride hexahydrate were immersed in a cell culture medium for 24 h at 37 ℃. hTERT-hNOFs and IHOK were cultured for 24 h. The cell culture medium was removed and extracts of the dental gingival retraction cords were added. After incubation with the extract solution, cell viability was evaluated using an MTT assay. The levels of the cytokines IL-1α and IL-8 were measured in the supernatants of each cell type. The cell viability after exposure to the extract solution for 10 min exceeded 70 % in both cell types. The ET50 values for hTERT-hNOF and IHOK were 35.75 and 28.98 min, respectively. For IHOK, the IL-1α level was (5.35 ± 5.22) pg/mL at 10 min, (3.58 ± 5.38) pg/mL at 20 min, and (2.85 ± 4.28) pg/mL at 60 min of exposure (p > 0.05). The IL-8 level in IHOK was (67.16 ± 18.70) pg/mL at 10 min, (78.36 ± 7.50) pg/mL at 20 min, and (111.9 ± 26.10) pg/mL at 60 min of exposure (p > 0.05). Cytokine release was not observed from hTERT-hNOFs. Based on these results, cell viability and cytokine release were confirmed in cells exposed to the impregnated gingival retraction cord. In addition, the application of the extracts to hTERT-hNOF and IHOK during the actual contact time and determination of ET50 may be beneficial for evaluating the biocompatibility of dental-impregnated gingival retraction cords.

• Journal of the Chungcheong Mathematical Society
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• v.7 no.1
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• pp.117-122
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• 1994

In this paper we show that if {$H_n$} is a continuous strong higher derivation of order n on an ultraprime Banach algebra with a constant c, then $c||H_1||^2{\leq}4||H_2||$ and for each $1{\leq}l$ < n $$c^2||H_1||\;||H_{n-l}{\leq}6||H_n||+\frac{3}{2}\sum_{\array{i+j+k=n\\i,j,k{\geq}1}}||H_i||\;||H_j||\;||H_k||+\frac{3}{2}\sum_{\array{i+k=n\\i{\neq}l,\;n-1}}||H_i||\;||H_k|| $$ and for a strong higher derivation {$H_n$} of order n on a prime ring A we also show that if [$H_n$(x),x]=0 for all $x{\in}A$ and for every $n{\geq}1$, then A is commutative or $H_n=0$ for every $n{\geq}1$.