• Title/Summary/Keyword: Kwon Young

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Screening of Thrombin Inhibitors from Medicinal and Wild Plants (약용 및 야생식물로부터 트롬빈 저해물질의 탐색)

  • Kwon, Yun-Sook;Kim, Young-Sook;Kwon, Ha-Young;Kwon, Gi-Seok;Kim, Kyung-Jae;Kwon, Chong-Suk;Son, Kun-Ho;Sohn, Ho-Yong
    • Korean Journal of Pharmacognosy
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    • v.35 no.1 s.136
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    • pp.52-61
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    • 2004
  • Inhibitory activities of 264 methanol extracts, which were prepared from different parts of 210 kinds of wild and medicinal plants, against human thrombin were evaluated. Based on the anti-coagulation activity determined by thrombin time and activated partial thromboplastin time, the 14 extracts were screened. The fibrinolytic activity, heat stability and inhibition of other proteolytic digestive enzymes, such as pepsin, papain, trypsin and chymotrypsin, of the 14 extracts were further determined, and Ginko biloba (herba), Ephedra sinica (radix), Reynoutria elliptica (herba), Amomum tsao-ko Crevost (fructus), and Magnolia officinalis Rehd. et Wils (bark) were finally selected as possible plant sources for anti-thrombosis agent. These results suggested that medicinal and wild plants could be the potential source of thrombin inhibitor.

Chaos Analysis of Major Joint Motions for Young Males During Walking (보행시 전신 주요 관절의 카오스 지수 분석)

  • Park, Jung-Hong;Son, Kwon;Seo, Kuk-Woong;Park, Young-Hoon
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.792-795
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    • 2007
  • To quantify irregular body motions the time series analysis was applied to the gait study. The motions obtained from gait experiment are complex to exhibit nonlinear behaviors. The purpose of this study is to measure quantitatively the characteristics of the major six joints of the body during walking. The gait experiments were carried out for eighteen young males walking on a motor driven treadmill. Joint motions were captured using eight video cameras, and then three dimensional kinematics of the neck and the upper and lower extremities were computed by KWON 3D motion analysis software. The largest Lyapunov exponent was calculated from the time series to quantify stabilities of each joint. The results provides a data set of nonlinear dynamic characteristics for six joints engaged in normal walking.

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Chemical Components and their Antioxidative Effect of Distylium racemosum

  • Park, Young-Ki;Lee, Wi-Young;Ahn, Jin-Kwon;Lee, Hak-Ju;Chin, Hwi-Seung;Kwon, Young-Jin
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.259.2-259.2
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    • 2003
  • This study was carried out to isolate and to identify the compounds and to find out antioxidants from the leaf of Distylium racemosum which belongs to Hamamelidaceae family. To isolate compounds, leaf of this plant were extracted with 50% Acetone and then crude extracts was partitioned with hexane. ether and ethyl acetate (EtOAc) successively. After partitioned, EtOAc fraction was subjected to column chromatography with various solvent systems in silica gel and/or Sephadex LH-20. (omitted)

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