• Journal of Ginseng Research
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• v.18 no.3
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• pp.200-203
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• 1994

Recent trend of ginseng (p. ginseng) trade in Japan was analyzed. From 1984 white ginseng import increased continuously to 240% while export of red ginseng decreased to 29%. Red ginseng import increased until 1990 and decreased thereafter, resulting in 12% of total import ginseng in 1993 from 47% in 1990. During five years (1989∼1993) white ginseng import from Korea decreased from 44% to 14% of total white ginseng imported while import from China increased. Red ginseng import from China ranged 97 to l00% of total red ginseng and little change was shown during five years. Price of Korean ginseng was higher than that of China by 2.2 times for white and 6.6 times for red. The continuous decrease of Chinese ginseng price might affect import trend. Export price of red ginseng increased continuously and was higher than that of Korean red ginseng (1.95 times) and much higher than import price (20 times in 1993).

• Journal of Ginseng Research
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• v.15 no.2
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• pp.117-119
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• 1991

In continuation of previous isolation of two lignan components, Gomisin A and -N, from Korean Red Ginseng the presence of the two lignans was identified in the hexane extract of Korean White Ginseng by gas chromatographic analysis.

• Journal of Ginseng Research
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• v.9 no.2
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• pp.256-263
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• 1985

In order to investigate the inferior factor of red ginseng quality, the contents of various chemical components, physico-chemical properties and arrangement state of ginseng cells were observed. Contents of total reducing sugar, reducing sugar, crude protein, crude fibre and specific gravity of inside white part of red ginseng were less than those of normal part. But differences in content of crude saponin, HPLC pattern of ginsenosides and reducing ability for DP P H(1,1-dipheny 1-2-picrylhydrazyl) between normal and inside white part of red ginseng were not found. The optical density of 1 water extract of normal part of red ginseng did not differ from that of inside white 1 part of red ginseng, but the visible and UV absorbance of acid hydrolyzate of normal red ginseng showed higher than those of inside white part of red ginseng. The differences in the internal color and tissue of normal and inside white part of red ginseng were easily found with naked eye, and by the microscopic fractography, the orangement state of ginseng cell in the inside white part of red ginseng was less dense than that in normal red ginseng.

• Journal of Ginseng Research
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• v.25 no.2
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• pp.68-73
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• 2001

Studies were performed to determine the effect of red ginseng and white ginseng on jejunal crypt survival, endogenous spleen colony formation, and apoptosis of jejunal crypt cells in irradiated mice. The radioprotective effect of ginseng was compared with the effect of diethyldithocarbamate(D). Jejunal crypts were protected from irradiation by pretreatment of red ginseng (50 mg/kg B.W., I.P. at 36 and 12 hours before irradiation) and white ginseng (50 mg/kg B.W., I.P. at 36 and 12 hours before irradiation). Red ginseng administration before irradiation and both pretreatment and posttreatment (50 mg/kg B.W., I.P. at 30 minutes after irradiation) of white ginseng resulted in an increase of the formation of endogenous spleen colony. the frequency of radiation-induced apoptosis in intestinal crypt cells was also reduced by both pretreatment and posttreatment of red ginseng, and pretreatment of white ginseng. The radioprotective effect of DDC (1000 mg/kg B.W., I.P. at 30 minutes before irradiation) on jejunal crypt survival and apoptosis was similar to those of ginseng treatment. Treatment with DDC showed no significant modifying effects on formation of endogenous spleen colony. These results indicated that ginseng might be a useful radioprotector. Further studies are needed to characterize effective radioprotective components and mechanism of ginseng.

• Journal of Ginseng Research
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• v.34 no.4
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• pp.348-354
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• 2010

Black ginseng and white ginseng were extracted with 80% ethanol and evaluated for relative ginsenoside composition, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities, and antioxidant properties. As analyzed by HPLC, black ginseng contained a greater proportion of ginsenoside $Rg_3$ compared to white ginseng. White ginseng was characterized by undetectable ginsenoside $Rg_3$ but it contained more total ginsenosides than black ginseng. Black ginseng extract exhibited higher (p<0.05) free radical-scavenging activity, as well as higher antioxidant activities than white ginseng against 2,2-diphenyl-1-picryl-hydrazyl, superoxide dismutase, and xanthine oxidase, despite the fact that the total saponin content was higher in white ginseng than black ginseng. In addition, the black ginseng extract displayed greater AChE and BChE inhibitory activities. These results suggest that black ginseng has stronger effects on anti-oxidation and AChE and BChE inhibition than white ginseng.

• Korean Journal of Pharmacognosy
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• v.45 no.1
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• pp.77-83
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• 2014

The purpose of this study is to develop a new preparation process of ginseng extracts having high concentrations of ginsenoside $Rg_3$, $Rg_5$ and $Rk_1$, a special component of Red ginseng. Chemical transformation from ginseng saponin glycosides to prosapogenin was analyzed by the HPLC. Extracts of White ginseng (Panax ginseng) and Fine White ginseng were processed under several treatment conditions including microwave and vinegar (about 14% acidity) treatments. Results of those treatments showed that the quantity of ginsenoside $Rg_3$ increased by over 0.6% at 4 minutes of pH 2~4 vinegar and microwave treatments. The results of processing with MWG-4 indicate that the Microwave and vinegar processed white ginseng extracts (about 14% acidity) that had gone through 4-minute treatments were found to contain the largest amount of ginsenoside $Rg_3$ (0.626%), $Rg_5$ (0.514%) and $Rk_1$ (0.220%). Results of treatments with MFWG-5 showed that the Fine White ginseng extracts that had been processed with microwave and vinegar (about 14% acidity) for 5 minutes were found to contain the largest amount of ginsenoside $Rg_3$ (4.484%), $Rg_5$ (3.192%) and $Rk_1$ (1.684%). It is thought that such results provide basic information in preparing White ginseng and Fine White ginseng extracts with functionality enhanced.

• Journal of Microbiology and Biotechnology
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• v.18 no.11
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• pp.1789-1791
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• 2008

This study was aimed (i) to develop an effective method for the purification of ginsenosides for industrial use and (ii) to compare the distribution of ginsenosides in cultured wild ginseng roots (adventitious root culture of Panax ginseng) with those of red ginseng (steamed ginseng) and white ginseng (air-dried ginseng). The crude extracts of cultured wild ginseng roots, red ginseng, and white ginseng were obtained by using a 75% ethanol extraction combined with ultrasonication. This was followed sequentially by AB-8 macroporous adsorption chromatography, Amberlite IRA 900 Cl anion-exchange chromatography, and Amberlite XAD16 adsorption chromatography for further purification. The contents of total ginsenosides were increased from 4.1%, 12.1%, and 11.3% in the crude extracts of cultured wild ginseng roots, red ginseng, and white ginseng to 79.4%, 71.7%, and 72.5% in the final products, respectively. HPLC analysis demonstrated that ginsenosides in cultured wild ginseng roots were distributed in a different ratio compared with red ginseng and white ginseng.

• Korean Journal of Pharmacognosy
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• v.48 no.1
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• pp.82-87
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• 2017

Malonyl ginsenoside content of the Panax ginseng C.A. Meyer is known to account for 35% to 60% of total ginsenosides content. However, its distribution by ginseng part has not been studied. In this study, four kinds of malonyl ginsenosides were compared in Korean white ginseng part using the purified malonyl ginsenoside standards in our laboratory. White ginseng was prepared by the freeze drying ($-70^{\circ}C$, 48 h) or air drying ($50^{\circ}C$, 48 h) methods form 4-year-old ginseng. Malonyl ginsenoside content of main, lateral, and fine root, and of the main root without skin and its skin was compared. Malonyl ginsenosides (m-Rb1, m-Rb2, m-Rc and m-Rd) content (58%, 19.17 mg/g) in total ginsenosides of air dried white ginseng was decreased about 4% compared to its content of freeze dried white ginseng (62%, 20.40 mg/g). Malonyl ginsenoside content was the highest in fine root, compared to the main or lateral root. Malonyl ginsenosides content in skin of main root was 20.08 mg/g, while its content of the main root without skin was 2.58 mg/g. These results are expected to help establishment of quality specification and processing process in Korean white ginseng.

• Korean Journal of Food Science and Technology
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• v.11 no.3
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• pp.182-187
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• 1979

Six commercial ginseng products, red ginseng, white ginseng I and II, red ginseng extract, white ginseng extract I and II were extracted with ethyl ether. Total fatty acid composition of the extracted free lipids was analyzed by gas liquid chromatography and digital integrator was used to measure the area of each peak. Crude lipid contents of red and white ginsengs were similiar. Those of red ginseng extract, white ginseng extract I and II were 1.10, 1.13 and 0.40%, respectively. It was found that 22 kinds of fatty acids existed in red and white ginsengs. Among them, 16 kinds of even numbered fatty acids were identified. Linoleic acid in red and white ginsengs was the most abundant. The contents of that in red ginseng, white ginseng I and II were 63.33, 45.55 and 41.06%, respectively. The next most abundant acid was palmitic acid, the contents of which were 11.30, 14.4 and 18.10% for red ginseng, white ginseng I and II, respectively. Major fatty acids for red ginseng extract and white ginseng extract I were linoleic and palmitic acids in the same order of magnitude. Linoleic and palmitic acids for red ginseng extract were 15.93 and 15.71 %, respectively, while linoleic and palmitic acids for white ginseng extract I were 21.94 and 19.15%, respectively. However, white ginseng extract II contained only 9.21% of linoleic acid and 16.13% of palmitic acid which was the major fatty acid.

• Journal of Sericultural and Entomological Science
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• v.22 no.1
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• pp.59-62
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• 1980

The effect of dietary white ginseng on growth of silkworm larva was studied with several young and grown silkworm larvae divided into four groups and fed ad basal artificial diet containing different levels of ginseng extract. The four levels of ginseng extract added to basal artificial diet were: 0 (control), 46.6, 139.9 and 279.8 mg per g of dry diet. The results obtained were as follows: 1. The body weight of silkworm larvae fed ad basal artificial diet containing different levels of ginseng extract was increased in 46.6mg ginseng extract level, 139.9mg ginseng extract level and 279.8mg ginseng extract level order. The body weight was greatly increased in 46.6mg ginseng extract level than in control. It is, therefore. considered that a little white ginseng was effective for larval growth in silkworm rearing with artificial diet. 2. The blood sugar content of silkworm larvae fed on an artificial diet containing several levels of ginseng extract was remarkably decreased as compared wilt that of the control silkworm larvae.