• 제목/요약/키워드: Korean project spectrum

검색결과 51건 처리시간 0.011초

Korean Red Ginseng extract treatment prevents post-antibiotic dysbiosis-induced bone loss in mice

  • Ho Jun Kang;Nicholas Chargo;Soumya Chennupati;Kerri Neugebauer;Jae Youl Cho;Robert Quinn;Laura R. McCabe;Narayanan Parameswaran
    • Journal of Ginseng Research
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    • 제47권2호
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    • pp.265-273
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    • 2023
  • Background: The intestinal microbiota is an important regulator of bone health. In previous studies we have shown that intestinal microbiota dysbiosis, induced by treatment with broad spectrum antibiotics (ABX) followed by natural repopulation, results in gut barrier dysfunction and bone loss. We have also shown that treatment with probiotics or a gut barrier enhancer can inhibit dysbiosis-induced bone loss. The overall goal of this project was to test the effect of Korean Red Ginseng (KRG) extract on bone and gut health using antibiotics (ABX) dysbiosis-induced bone loss model in mice. Methods: Adult male mice (Balb/C, 12-week old) were administered broad spectrum antibiotics (ampicillin and neomycin) for 2 weeks followed by 4 weeks of natural repopulation. During this 4-week period, mice were treated with vehicle (water) or KRG extract. Other controls included mice that did not receive either antibiotics or KRG extract and mice that received only KRG extract. At the end of the experiments, we assessed various parameters to assess bone, microbiota and in vivo intestinal permeability. Results: Consistent with our previous results, post-ABX- dysbiosis led to significant bone loss. Importantly, this was associated with a decrease in gut microbiota alpha diversity and an increase in intestinal permeability. All these effects including bone loss were prevented by KRG extract treatment. Furthermore, our studies identified multiple genera including Lactobacillus and rc4-4 as well as Alistipes finegoldii to be potentially linked to the effect of KRG extract on gut-bone axis. Conclusion: Together, our results demonstrate that KRG extract regulates the gut-bone axis and is effective at preventing dysbiosis-induced bone loss in mice.

경관도로 등 신개념의 도로사업 개발에 관한 연구 (A Strategy for Developing New Road Projects)

  • 김응철
    • 한국도로학회논문집
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    • 제9권2호
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    • pp.115-127
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    • 2007
  • 최근 도로선진국이라 할 수 있는 나라들에서는 다양한 도로사업의 발굴 및 장려정책이 도입되고 있다. 본 논문에서는 새로운 도로사업의 발굴을 위한 대안모형을 제시하였다. 새로운 도로사업 발굴을 위한 절차로는 근거법령의 모색 신개념 도로사업의 발굴, 평가 모형구축 및 운영지침 개발, 관련행정체계 개선 등 크게 4가지의 주요 절차가 필요한 것으로 제시되었다. 근거법령의 모색은 도로법 및 도로법 시행령, 시행규칙 등이 우선 고려되어야 할 것으로 분석되었으며 신개념의 도로사업 발굴절차는 크게 국가적 차원의 유일성 확보 도로, 다양한 가치기준에 의해 선정되는 도로 및 단일시설, 기술(설계 우수VE 및 LCCA사례 포함) 및 구조물 형태로서 발굴될 수 있는 사례로 세분류하였다. 평가모형 구축 및 운영지침 개발절차에서는 미국 NSBP프로그램의 절차 혹은 지속가능한 도시대상의 절차를 사례로 할 수 있으며 분석적 계층화법(AHP) 및 다지역산업연관모형(MRIO)의 적용가능성도 제시하였다. 또한, 관련 행정체계의 개선에서는 건설교통부의 도로기획관실 업무내역 분석을 통해 도로정책팀과 도로환경팀의 역할을 제시하였으며 평가위원회의 구성, 평가과정과 일체화된 예산지원절차를 추진방안으로 제시하였다.

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가정의 물리적, 인적 음악 환경과 아동의 음악성 발달에 관한 연구 (A Study on Musical Home Environment and Children's Musical Development)

  • 김명순;이소희
    • 대한가정학회지
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    • 제37권7호
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    • pp.83-94
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    • 1999
  • The purpose of this study was to explore musical development of 3- to S-year-old children and their musical home environment. The subjects were one hundred ninety-four children and their mothers enrolled in four kindergartens in Seoul. Each child sang the birthday song with peers in a birthday play setting. It was audiotaped for the children to sing the song. Questionnaire of musical home environment developed by the researchers was used for the mothers. The children's rhythm and pitch development were coded by the scoring categories of Project Spectrum(Krechevsky, 1994). The data were analyzed by t-test, ANOVA, Scheffe, and Pearson correlation. The results of this study were as follows: Firstly, there was no a significant difference in the children's rhythm development among three age-groups as well as between boys and girls. Among rhythm subcategories, the unit of note was ranked in the highest score and the pulse the next. Secondly, there were significant differences in children's pitch development among three age-groups and between boys and girls. The older children significantly achieved higher scores than the younger. Among pitch subcategories, the contour was ranked in the highest score and the interval the next. Thirdly, the children's musical development and their physical home environment related to music were correlated positively. The children's pitch development was significantly related to the mothers' musical attitude and the children's rhythm development to the mothers' educational levels.

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유치원 특성 변인이 $4{\sim}5$세 유아의 운동능력에 미치는 영향 (The Effect of Kindergarten's Factors on Athletic Movement Ability in $4{\sim}5$ Years Old Children)

  • 오연주
    • 한국생활과학회지
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    • 제13권3호
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    • pp.407-415
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    • 2004
  • The purpose of this study was to investigate the effect of kindergarten's factors on athletic movement ability in early childhood. The factors included teacher's perception of athletic movement, length of time for physical activity, and number of athletic facilities in the kindergarten. The subjects consisted of 551 children aged from four to five years in 8 private kindergartens. The instruments used for this study were the obstacle course of Project Spectrum for measuring athletic movement ability, and the questionnaire to investigate the teacher's perception, length of time for physical activity, and number of athletic facilities in the kindergarten. The data from all the tests were analyzed by correlation and regression analyses. The results of this study exhibited that the length of time for physical activity was the most important factor among three factors, and the teachers' perception of athletic movement and the number of athletic facilities in the kindergarten were also deciding factors for the children's athletic movement ability.

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OC3 Hywind 부유식 풍력발전기 플랫폼의 유체력 계산 및 운동해석 (Hydrodynamic force calculation and motion analysis of OC3 Hywind floating offshore wind turbine platform)

  • 김민수;이강수
    • Journal of Advanced Marine Engineering and Technology
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    • 제37권8호
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    • pp.953-961
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    • 2013
  • 이 연구에서는 부유식 풍력발전기 콘셉트모델중의 하나인 5MW급 OC3-Hywind를 해석하였다. 이 모델은 스파형 플랫폼을 가지고 있으며 3개의 현수식 계류삭으로 해저면과 연결되어있다. 수치해석프로그램으로는 NREL에서 개발한 FAST와 AQWA가 사용되었다. FAST에 입력되는 유체력은 AQWA를 통해서 계산되었으며, 운동특성으로는 전달응답함수와 평균운동, 상위1/3운동, 상위1/10운동을 평가하였다. 다른기관의 해석, 실험결과와 비교하였으며, 이 결과는 부유식풍력발전기 컨셉모델의 기초설계를 재해석하는데 있어 도움이 될것이다.

빅데이터 분석을 위해 아파치 스파크를 이용한 원시 데이터 소스에서 데이터 추출 (Capturing Data from Untapped Sources using Apache Spark for Big Data Analytics)

  • ;구흥서
    • 전기학회논문지
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    • 제65권7호
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    • pp.1277-1282
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    • 2016
  • The term "Big Data" has been defined to encapsulate a broad spectrum of data sources and data formats. It is often described to be unstructured data due to its properties of variety in data formats. Even though the traditional methods of structuring data in rows and columns have been reinvented into column families, key-value or completely replaced with JSON documents in document-based databases, the fact still remains that data have to be reshaped to conform to certain structure in order to persistently store the data on disc. ETL processes are key in restructuring data. However, ETL processes incur additional processing overhead and also require that data sources are maintained in predefined formats. Consequently, data in certain formats are completely ignored because designing ETL processes to cater for all possible data formats is almost impossible. Potentially, these unconsidered data sources can provide useful insights when incorporated into big data analytics. In this project, using big data solution, Apache Spark, we tapped into other sources of data stored in their raw formats such as various text files, compressed files etc and incorporated the data with persistently stored enterprise data in MongoDB for overall data analytics using MongoDB Aggregation Framework and MapReduce. This significantly differs from the traditional ETL systems in the sense that it is compactible regardless of the data formats at source.

Comparison of Environmental Radiation Survey Analysis Results in a High Dose Rate Environment Using CZT, NaI(Tl), and LaBr3(Ce) Detectors

  • Sungyeop Joung;Wanook Ji;Eunjung Lee;Young-Yong Ji;Yoomi Choi
    • 방사성폐기물학회지
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    • 제21권4호
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    • pp.543-558
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    • 2023
  • Currently, Japan is undertaking a nationwide project to measure and map radioactive contamination around Fukushima, as part of the efforts to restore normalcy following the nuclear accident. The Japan Atomic Energy Agency (JAEA) manages the Fukushima Environmental Safety Center, located approximately 20 km north of the Fukushima Daiichi nuclear power plant in Minamisōma City, Fukushima Prefecture. In collaboration with the JAEA, this study involved conducting comparison experiments and analyses with radiation detectors in high radiation environments, a challenging task in Korean environments. Environmental radiation surveys were conducted using three types of detectors: CZT, NaI(Tl), and LaBr3(Ce), across two contaminated areas. Dose rate values were converted using dose rate conversion factors for each detector type, and dose rate maps were subsequently created and compared. The detectors yielded similar results, demonstrating their feasibility and reliability in high radiation environments. The findings of this study are expected to be a crucial reference for enhancing the verification and supplementation of procedures and methods in future radiation measurements and mobile surveys in high-radiation environments, using these three types of radiation instruments.

A Study on the High-Order Spectral Model Capability to Simulate a Fully Developed Nonlinear Sea States

  • Young Jun Kim;Hyung Min Baek;Young Jun Yang;Eun Soo Kim;Young-Myung Choi
    • 한국해양공학회지
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    • 제37권1호
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    • pp.20-30
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    • 2023
  • Modeling a nonlinear ocean wave is one of the primary concerns in ocean engineering and naval architecture to perform an accurate numerical study of wave-structure interactions. The high-order spectral (HOS) method, which can simulate nonlinear waves accurately and efficiently, was investigated to see its capability for nonlinear wave generation. An open-source (distributed under the terms of GPLv3) project named "HOS-ocean" was used in the present study. A parametric study on the "HOS-ocean" was performed with three-hour simulations of long-crested ocean waves. The considered sea conditions ranged from sea state 3 to sea state 7. One hundred simulations with fixed computational parameters but different random seeds were conducted to obtain representative results. The influences of HOS computational parameters were investigated using spectral analysis and the distribution of wave crests. The probability distributions of the wave crest were compared with the Rayleigh (first-order), Forristall (second-order), and Huang (empirical formula) distributions. The results verified that the HOS method could simulate the nonlinearity of ocean waves. A set of HOS computational parameters was suggested for the long-crested irregular wave simulation in sea states 3 to 7.

적외선 우주배경복사 관측 실험 2(CIBER2) 국제 공동 연구 (KOREAN PARTICIPATION ON THE COSMIC INFRARED BACKGROUND EXPERIMENT 2 (CIBER2))

  • 이대희;박원기;문봉곤;박성준;김민규;김건희;남욱원;표정현;정웅섭;박영식;김일중;한원용
    • 천문학논총
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    • 제30권1호
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    • pp.11-16
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    • 2015
  • First light galaxies have predictable linear clustering, and are expected to produce fluctuations with a characteristic spatial power spectrum, which peaks at an angular scale of ~ 10 arcminutes and in the $1-2{\mu}m$ spectral regions. The Cosmic Infrared Background ExpeRiment 2 (CIBER2) is a dedicated sounding rocket mission for measuring the fluctuations in the extragalactic infrared background light, following up the previous successful measurements of CIBER1. With a 28.5 cm telescope accompanied with three arms of camera barrels and a dual broadband filter on each H2RG (${\lambda}_c=2.5{\mu}m$) array, CIBER2 can measure 6 bands of wide field ($1.1{\times}2.2$ degrees) up to 3 AB magnitudes deeper than CIBER1. This project is leaded by California Institute of Technology/Jet Propulsion Laboratory, collaborating internationally with Institute of Space and Astronautical Science in Japan, Korea Astronomy and Space Science Institute, Korea Basic Science Institute, and Seoul National University. The Korean team is in charge of 1) one H2RG scientific array, 2) ground station hardware and software, 3) telescope lenses, and 4) flight and test bed electronics fabrication. In this paper, we describe the detailed activities of the Korean participation as well as the current status of the CIBER2 project.

연안선박용 LNG 벙커링 전용선박의 내항성능 평가에 대한 연구 (Performance Assessment of Navigation Seakeeping for Coastal Liquified-Natural-Gas Bunkering Ship)

  • 이민아;박준범;이창희
    • 해양환경안전학회지
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    • 제26권7호
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    • pp.904-914
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    • 2020
  • 우리나라는 산업통상자원부를 통해 'LNG 벙커링(연료공급) 전용선 건조지원사업'을 한국가스공사를 중심으로 추진하고 있고, 동시 해양수산부는 부산신항내 LNG 벙커링 터미널 구축을 추진하고 있다. LNG 벙커링 전용선박은 LNG 연료를 터미널에서 대상 선박으로 공급하기 위한 필수 대상이고, 이에 따라 안정 운항에 대한 절차서의 필요성이 대두되고 있다. 따라서 본 연구는 연안선박용 LNG벙커링 전용선박의 운항 절차서를 제안하기 위하여 부산 신항에서 부산항 정박지로 운항하는 연안선박용 LNG 벙커링 전용선박의 안정성을 평가하였다. 이를 위해 포텐셜 유동해석 기반의 운동해석을 수행하여 취득한 선체운동 응답진폭함수를 운항 해역의 5년간 관측된 실해역 자료와 부산 연안에 적합한 TMA스펙트럼과 합성하여 유의파고별 연안선박용 LNG 벙커링 전용 선박의 내항성능 평가를 수행하였다. 그 결과는 유의파고 2 m 이상에서 횡동요와 수평가속도가 내항성능에 주요 위험 요소가 됨을 알 수 있었다. LNG 벙커링 전용선박의 운항 가능 기간은 총 관측기간의 83.3 ~ 99.9 % 수준임을 알 수 있었다.