• Title/Summary/Keyword: Korean project spectrum

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Korean Red Ginseng extract treatment prevents post-antibiotic dysbiosis-induced bone loss in mice

  • Ho Jun Kang;Nicholas Chargo;Soumya Chennupati;Kerri Neugebauer;Jae Youl Cho;Robert Quinn;Laura R. McCabe;Narayanan Parameswaran
    • Journal of Ginseng Research
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    • v.47 no.2
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    • pp.265-273
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    • 2023
  • Background: The intestinal microbiota is an important regulator of bone health. In previous studies we have shown that intestinal microbiota dysbiosis, induced by treatment with broad spectrum antibiotics (ABX) followed by natural repopulation, results in gut barrier dysfunction and bone loss. We have also shown that treatment with probiotics or a gut barrier enhancer can inhibit dysbiosis-induced bone loss. The overall goal of this project was to test the effect of Korean Red Ginseng (KRG) extract on bone and gut health using antibiotics (ABX) dysbiosis-induced bone loss model in mice. Methods: Adult male mice (Balb/C, 12-week old) were administered broad spectrum antibiotics (ampicillin and neomycin) for 2 weeks followed by 4 weeks of natural repopulation. During this 4-week period, mice were treated with vehicle (water) or KRG extract. Other controls included mice that did not receive either antibiotics or KRG extract and mice that received only KRG extract. At the end of the experiments, we assessed various parameters to assess bone, microbiota and in vivo intestinal permeability. Results: Consistent with our previous results, post-ABX- dysbiosis led to significant bone loss. Importantly, this was associated with a decrease in gut microbiota alpha diversity and an increase in intestinal permeability. All these effects including bone loss were prevented by KRG extract treatment. Furthermore, our studies identified multiple genera including Lactobacillus and rc4-4 as well as Alistipes finegoldii to be potentially linked to the effect of KRG extract on gut-bone axis. Conclusion: Together, our results demonstrate that KRG extract regulates the gut-bone axis and is effective at preventing dysbiosis-induced bone loss in mice.

A Strategy for Developing New Road Projects (경관도로 등 신개념의 도로사업 개발에 관한 연구)

  • Kim, Eung-Cheol
    • International Journal of Highway Engineering
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    • v.9 no.2 s.32
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    • pp.115-127
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    • 2007
  • Developed countries, especially in road construction and management fields, introduce new road porjects such as National Scenic Byways Program(NSBP program) in USA and the Eco-road project in Japan. This study develops a conceptual model for deploying new road projects in Korea. The four step approach is suggested to create new road projects, including foundation of an act based on the existing Road Act, creation of new road project ideas, development of evaluation process and guidelines, and enhancement of an administrative scheme. To create new road projects, three different ways are devised; (1) designation of national roads having uniqueness in overall spectrum, (2) designation of roads having intrinsic values in a different aspect, (3) designation of single structures of engineering outcomes such as bridges, tunnels, new design techniques, considerable Value Engineering output, and well analyzed Life Cycle Cost Analysis practices. For the evaluation process, NSBP program of USA and/or Sustainable City Award program of Korea would be recommended. An administrative scheme and integrated funding process for the new road projects are also suggested based on evaluation of tasks of each team or division of Korea Ministry of Construction and Transportation.

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A Study on Musical Home Environment and Children's Musical Development (가정의 물리적, 인적 음악 환경과 아동의 음악성 발달에 관한 연구)

  • 김명순;이소희
    • Journal of the Korean Home Economics Association
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    • v.37 no.7
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    • pp.83-94
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    • 1999
  • The purpose of this study was to explore musical development of 3- to S-year-old children and their musical home environment. The subjects were one hundred ninety-four children and their mothers enrolled in four kindergartens in Seoul. Each child sang the birthday song with peers in a birthday play setting. It was audiotaped for the children to sing the song. Questionnaire of musical home environment developed by the researchers was used for the mothers. The children's rhythm and pitch development were coded by the scoring categories of Project Spectrum(Krechevsky, 1994). The data were analyzed by t-test, ANOVA, Scheffe, and Pearson correlation. The results of this study were as follows: Firstly, there was no a significant difference in the children's rhythm development among three age-groups as well as between boys and girls. Among rhythm subcategories, the unit of note was ranked in the highest score and the pulse the next. Secondly, there were significant differences in children's pitch development among three age-groups and between boys and girls. The older children significantly achieved higher scores than the younger. Among pitch subcategories, the contour was ranked in the highest score and the interval the next. Thirdly, the children's musical development and their physical home environment related to music were correlated positively. The children's pitch development was significantly related to the mothers' musical attitude and the children's rhythm development to the mothers' educational levels.

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The Effect of Kindergarten's Factors on Athletic Movement Ability in $4{\sim}5$ Years Old Children (유치원 특성 변인이 $4{\sim}5$세 유아의 운동능력에 미치는 영향)

  • Oh, Yeon-Joo
    • Korean Journal of Human Ecology
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    • v.13 no.3
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    • pp.407-415
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    • 2004
  • The purpose of this study was to investigate the effect of kindergarten's factors on athletic movement ability in early childhood. The factors included teacher's perception of athletic movement, length of time for physical activity, and number of athletic facilities in the kindergarten. The subjects consisted of 551 children aged from four to five years in 8 private kindergartens. The instruments used for this study were the obstacle course of Project Spectrum for measuring athletic movement ability, and the questionnaire to investigate the teacher's perception, length of time for physical activity, and number of athletic facilities in the kindergarten. The data from all the tests were analyzed by correlation and regression analyses. The results of this study exhibited that the length of time for physical activity was the most important factor among three factors, and the teachers' perception of athletic movement and the number of athletic facilities in the kindergarten were also deciding factors for the children's athletic movement ability.

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Hydrodynamic force calculation and motion analysis of OC3 Hywind floating offshore wind turbine platform (OC3 Hywind 부유식 풍력발전기 플랫폼의 유체력 계산 및 운동해석)

  • Kim, Min-Su;Lee, Kang-Su
    • Journal of Advanced Marine Engineering and Technology
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    • v.37 no.8
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    • pp.953-961
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    • 2013
  • In this study, the analyzed turbine is a 5MW upwind-type wind turbine. This conceptual model was made to compare the results of the numerical analysis program in the IEA Annex23 Subtask2 OC3 project. The numerical analysis program used in this study is FAST developed by NREL and AQWA of ANSYS. Motion characteristics, such as RAO, average motion, significant motion and average amplitude of 1/10 highest motion were obtained through the numerical analysis. The results of the numerical analysis were compared with the results of other numerical analyses and the experimental results, and all the results agreed with one another. The results will help resolve the fundamental design trade-offs between basic floating system concepts.

Capturing Data from Untapped Sources using Apache Spark for Big Data Analytics (빅데이터 분석을 위해 아파치 스파크를 이용한 원시 데이터 소스에서 데이터 추출)

  • Nichie, Aaron;Koo, Heung-Seo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.65 no.7
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    • pp.1277-1282
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    • 2016
  • The term "Big Data" has been defined to encapsulate a broad spectrum of data sources and data formats. It is often described to be unstructured data due to its properties of variety in data formats. Even though the traditional methods of structuring data in rows and columns have been reinvented into column families, key-value or completely replaced with JSON documents in document-based databases, the fact still remains that data have to be reshaped to conform to certain structure in order to persistently store the data on disc. ETL processes are key in restructuring data. However, ETL processes incur additional processing overhead and also require that data sources are maintained in predefined formats. Consequently, data in certain formats are completely ignored because designing ETL processes to cater for all possible data formats is almost impossible. Potentially, these unconsidered data sources can provide useful insights when incorporated into big data analytics. In this project, using big data solution, Apache Spark, we tapped into other sources of data stored in their raw formats such as various text files, compressed files etc and incorporated the data with persistently stored enterprise data in MongoDB for overall data analytics using MongoDB Aggregation Framework and MapReduce. This significantly differs from the traditional ETL systems in the sense that it is compactible regardless of the data formats at source.

Comparison of Environmental Radiation Survey Analysis Results in a High Dose Rate Environment Using CZT, NaI(Tl), and LaBr3(Ce) Detectors

  • Sungyeop Joung;Wanook Ji;Eunjung Lee;Young-Yong Ji;Yoomi Choi
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.21 no.4
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    • pp.543-558
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    • 2023
  • Currently, Japan is undertaking a nationwide project to measure and map radioactive contamination around Fukushima, as part of the efforts to restore normalcy following the nuclear accident. The Japan Atomic Energy Agency (JAEA) manages the Fukushima Environmental Safety Center, located approximately 20 km north of the Fukushima Daiichi nuclear power plant in Minamisōma City, Fukushima Prefecture. In collaboration with the JAEA, this study involved conducting comparison experiments and analyses with radiation detectors in high radiation environments, a challenging task in Korean environments. Environmental radiation surveys were conducted using three types of detectors: CZT, NaI(Tl), and LaBr3(Ce), across two contaminated areas. Dose rate values were converted using dose rate conversion factors for each detector type, and dose rate maps were subsequently created and compared. The detectors yielded similar results, demonstrating their feasibility and reliability in high radiation environments. The findings of this study are expected to be a crucial reference for enhancing the verification and supplementation of procedures and methods in future radiation measurements and mobile surveys in high-radiation environments, using these three types of radiation instruments.

A Study on the High-Order Spectral Model Capability to Simulate a Fully Developed Nonlinear Sea States

  • Young Jun Kim;Hyung Min Baek;Young Jun Yang;Eun Soo Kim;Young-Myung Choi
    • Journal of Ocean Engineering and Technology
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    • v.37 no.1
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    • pp.20-30
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    • 2023
  • Modeling a nonlinear ocean wave is one of the primary concerns in ocean engineering and naval architecture to perform an accurate numerical study of wave-structure interactions. The high-order spectral (HOS) method, which can simulate nonlinear waves accurately and efficiently, was investigated to see its capability for nonlinear wave generation. An open-source (distributed under the terms of GPLv3) project named "HOS-ocean" was used in the present study. A parametric study on the "HOS-ocean" was performed with three-hour simulations of long-crested ocean waves. The considered sea conditions ranged from sea state 3 to sea state 7. One hundred simulations with fixed computational parameters but different random seeds were conducted to obtain representative results. The influences of HOS computational parameters were investigated using spectral analysis and the distribution of wave crests. The probability distributions of the wave crest were compared with the Rayleigh (first-order), Forristall (second-order), and Huang (empirical formula) distributions. The results verified that the HOS method could simulate the nonlinearity of ocean waves. A set of HOS computational parameters was suggested for the long-crested irregular wave simulation in sea states 3 to 7.

KOREAN PARTICIPATION ON THE COSMIC INFRARED BACKGROUND EXPERIMENT 2 (CIBER2) (적외선 우주배경복사 관측 실험 2(CIBER2) 국제 공동 연구)

  • Lee, D.H.;Park, W.K.;Moon, B.G.;Park, S.J.;Kim, M.G.;Kim, G.H.;Nam, U.W.;Pyo, J.;Jeong, W.S.;Park, Y.S.;Kim, I.J.;Han, W.
    • Publications of The Korean Astronomical Society
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    • v.30 no.1
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    • pp.11-16
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    • 2015
  • First light galaxies have predictable linear clustering, and are expected to produce fluctuations with a characteristic spatial power spectrum, which peaks at an angular scale of ~ 10 arcminutes and in the $1-2{\mu}m$ spectral regions. The Cosmic Infrared Background ExpeRiment 2 (CIBER2) is a dedicated sounding rocket mission for measuring the fluctuations in the extragalactic infrared background light, following up the previous successful measurements of CIBER1. With a 28.5 cm telescope accompanied with three arms of camera barrels and a dual broadband filter on each H2RG (${\lambda}_c=2.5{\mu}m$) array, CIBER2 can measure 6 bands of wide field ($1.1{\times}2.2$ degrees) up to 3 AB magnitudes deeper than CIBER1. This project is leaded by California Institute of Technology/Jet Propulsion Laboratory, collaborating internationally with Institute of Space and Astronautical Science in Japan, Korea Astronomy and Space Science Institute, Korea Basic Science Institute, and Seoul National University. The Korean team is in charge of 1) one H2RG scientific array, 2) ground station hardware and software, 3) telescope lenses, and 4) flight and test bed electronics fabrication. In this paper, we describe the detailed activities of the Korean participation as well as the current status of the CIBER2 project.

Performance Assessment of Navigation Seakeeping for Coastal Liquified-Natural-Gas Bunkering Ship (연안선박용 LNG 벙커링 전용선박의 내항성능 평가에 대한 연구)

  • Yi, Minah;Park, Jun-Bum;Lee, Chang-Hee
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.7
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    • pp.904-914
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    • 2020
  • Through the Ministry of Trade, Industry, and Energy, South Korea is trying to support the "Building Project for Liquified Natural Gas (LNG) Bunkering Ship," centered on the Korea Gas Corporation, while the Ministry of Maritime Af airs and Fisheries is pushing to construct an LNG bunkering terminal at Busan New Port. LNG bunkering ships are essential for supplying LNG fuel from the terminal to the ships, resulting in the need for safety operation procedures. Therefore, in this study, the stability of a coastal LNG bunkering ship operating from Busan New Port to the anchorage in Busan Port was assessed to investigate the need for operational procedures for coastal LNG bunkering ships. Seakeeping analysis of the LNG bunkering ship was performed for each significant wave height by combining the response amplitude operator from the ship motion analysis under the potential flow theory with the actual observed sea data for five years and Texel, Marsen, and Arsloe (TMA) spectrum suitable for the Busan coast. The results showed that the roll and horizontal acceleration were the main risks that affected the navigation seakeeping performance above a significance wave height of 2 m. The operational periods of the LNG bunkering ship ranged from 83.3% to 99.9% of the total observation period.