• The Journal of Pediatrics of Korean Medicine
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• v.31 no.4
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• pp.49-60
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• 2017

Objectives The purpose of this study is to report the effectiveness of Korean medicine on treating autism spectrum disorder (ASD) in childhood. Methods We treated an 8-years-old patient who was diagnosed with autism (grade II) with herbal medicine, acupuncture and electric moxibustion. Every 11 months, Korean-Childhood Autism Rating Scale (K-CARS) was used to assess the patient's symptom progression. Results After 21 months of Korean medicine treatment, the child's overall health was improved. Moreover, language ability, emotional control, memory and cognitive abilities got better, as well as anxiety, agitation, and aggressive behavior related to ASD were also decreased. K-CARS score at the initial stage of the treatment was 39.5 points, which can be considered as severe autism. After 11 months of the treatment, the K-CARS score was 34.5 points which is mild-moderate autism. Conclusions Korean medicine treatment can be effective in improving symptoms of ASD. However, further studies are needed to demonstrate the treatment benefits to ASD.

• Korean Journal of Childcare and Education
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• v.9 no.2
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• pp.357-377
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• 2013

This study aims to look for care quality factors reduce the daily stress of young children placed in care centers for long hours. Therefore, the research questions look into how the hours and care quality factors in child care centers affect young children's daily stress, and whether the care quality factor moderates the impact of the hours children spent in centers. The subjects in this study were 380 children from 3 to 5 years old from 10 child care centers. The Korean Preschool Daily Stress Scale(KPDSS) for children's daily stress and Early Childhood Environmental Rating Scale-Revised(ECERS-R) for quality of each classroom of centers were implemented. The main findings were summarized as following: (1) The more hours he/she spent in the center, the more stress he/she had. Children who spent 9 hours or more had more stress than children with 7 hours or less. (2) Among the 7 quality factors including space and furnishings, personal care routines, language reasoning, activities, interaction, program structure, parents staff, the interaction level between a teacher and a child and the level of parents and staff had the most impact on children's daily stress. (3) The qualitative factors of child care, language reasoning level, interaction level, parental support, and level of teachers reduced children's daily stress which was affected by the hours they spent in centers. Thus in order to reduce the daily stress of children who attend more than 9 hours a day, it is crucial to promote language reasoning activities and interaction between teachers and children and to improve parental support and teachers' professionalism.

• Clinical and Experimental Pediatrics
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• v.61 no.12
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• pp.403-406
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• 2018

Floating-Harbor syndrome is a rare autosomal dominant genetic disorder associated with SRCAP mutation. To date, approximately 50 cases of Floating-Harbor syndrome have been reported, but none have been reported in Korea yet. Floating-Harbor syndrome is characterized by delayed bony maturation, unique facial features, and language impairment. Here, we present a 6-year-old boy with a triangular face, deep-set protruding eyes, low-set ears, wide nose with narrow nasal bridge, short philtrum, long thin lips, clinodactyly, and developmental delay that was transferred to our pediatric clinic for genetic evaluation. He showed progressive delay in the area of language and cognition-adaption as he grew. He had previously undergone chromosomal analysis at another hospital due to his language delay, but his karyotype was normal. We performed targeted exome sequencing, considering several syndromes with similar phenotypes. Library preparation was performed with the TruSight One sequencing panel, which enriches the sample for about 4,800 genes of clinical relevance. Massively parallel sequencing was conducted with NextSeq. An identified variant was confirmed by Sanger sequencing of the patient and his parents. Finally, the patient was confirmed as the first Korean case of Floating-Harbor syndrome with a novel SRCAP (Snf2 related CREBBP activator protein) mutation (c.7732dupT, p.Ser2578Phefs*6), resulting in early termination of the protein; it was not found in either of his healthy parents or a control population. To our knowledge, this is the first study to describe a boy with Floating-Harbor syndrome with a novel SRCAP mutation diagnosed by targeted exome sequencing in Korea.

• Korean Journal of Child Studies
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• v.30 no.2
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• pp.15-28
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• 2009

This study focused on the comprehension of texts written either in Korean script (Hangul) or Chinese script (Hanja). For this purpose, we measured the reading time and the correct response in text comprehension tasks with 104 Korean-Chinese children who were either 10 or 19 years old. There was a main effect of script : The reading time of Hanja texts was shorter than that of Hangul or Hangul Hanja mixed texts. But the older subjects who spent the same reading time in both Hangul and Hanja texts showed the longer reading time in Hangul Hanja mixed texts revealing the interaction between age and script. The correct response rate on the comprehension task was the highest in Hangul text. The results were discussed in relation to the independent dual language processing systems in Korean-Chinese.

• Speech Sciences
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• v.8 no.4
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• pp.99-107
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• 2001

The purpose of this study was to investigate the syllable and phoneme frequencies in the spontaneous speech of some Korean children. Sixty four normally developing children aged from 2 to 5 were involved (male: female=1 : 1, 16 children in each age group). Fifty connected utterances were analyzed using the KCLA (Korean Computerized Language Analysis) 2.0 and Exel. The findings were as follows: 1) /i/ was the most frequently used syllable and was followed by /yo/, /k/, /s'/, /nen/ and so on. 2) The most frequently used Korean phonemes were syllable-initial consonant /k/, syllable- medial vowel /a/ and syllable-final consonant /n/. 3) All seven syllable final consonants (/p,t,k,m,n,n,l/) were used more frequently in the word-medial position than in the word-final position. Three syllable initial consonants(/k, I, s'/) were used more frequently in the word-medial position than in the word-initial position. The syllable and phoneme frequencies in the Korean children's spontaneous speech will provide valuable information in interpreting the severity of phonological disorder and in developing tools for the Korean phonological assessment and intervention.

• The Korean Journal of Community Living Science
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• v.21 no.3
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• pp.299-310
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• 2010

The purpose of this study was to develop a scale to assess a Korean home environment for middle childhood children. The subjects were 283 mothers of 6- to 8-year-old children in Korea. The method for data analysis included Mean, SD, $x^2$, Cramer's V, factor analysis, Pearson correlations, and Cronbach's $\alpha$. As a result, 45 items of the scale were found to be satisfactory in terms of item distribution and item discrimination(Cramer's discriminant coefficients ranged from .256-.615). Four factors with 21 items were extracted from the factor analysis. Subscales were 'academic stimulation(9)', 'acceptance(4)', 'child-centered environment(4)', 'basic care for daily routine(4)'. Analysis of the relation of this scale to SES, MC-HOME, and children's developmental functioning(cognitive, language, and social) showed acceptable concurrent validity. Internal consistency of this scale was high, including internal reliability of subscales. These results confirm this scale as a valid and reliable measure of the Korean home environment for middle childhood children.

• Phonetics and Speech Sciences
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• v.5 no.3
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• pp.73-81
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• 2013

Coda in the word-medial position plays an important role in acquisition of our speech. Accuracy of the coda in the word-medial position is important as a diagnostic indicator since it has a close relationship with degrees of disorder. Coda in the word-medial position only appears in condition of connecting two vowels and the sequence causes diverse phonological processes to happen. The coda in the word-medial position differs in production difficulty by the initial sound in the sequence. Accordingly, this study aims to examine the tendency of producing a coda in the word-medial position with consideration of an optional phonological process in spontaneous speech of three and four year old children. Data was collected from 24 children (four groups by age) without speech and language delay. The results of the study are as follows: 1) Sonorant coda in the word-medial position showed a high production frequency in manner of articulation, and alveolar in place of articulation. When the coda in the word-medial position is connected to an initial sound in the same place of articulation, it revealed a high frequency of production. 2) The coda in word-medial position followed by an initial alveolar stop revealed a high error rate. Error patterns showed regressive assimilation predominantly. 3) The order of difficulty that Children had producing codas in the word-medial position was $/k^{\neg}/$, $/p^{\neg}/$, /m/, /n/, /ŋ/ and /l/. Those results suggest that in targeting coda in the word-medial position for evaluation, we should consider optional phonological process as well as the following initial sound. Further studies would be necessary which codas in the word-medial position will be used for therapeutic purpose.

• Pediatric Infection and Vaccine
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• v.29 no.1
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• pp.46-53
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• 2022

It is challenging to treat ventriculitis with parenteral treatment alone in some cases because of the difficulty involved in maintaining an appropriate level of antibiotics in cerebrospinal fluid (CSF). We report two cases of ventriculitis who did not respond to intravenous (IV) antibiotics but were successfully treated with intraventricular antibiotics using IV agents. The first case was a four-month-old male patient with X-linked hydrocephalus. He showed ventriculitis due to Klebsiella pneumoniae not producing extended-spectrum β-lactamase and susceptible to third-generation cephalosporins and gentamicin, following ventriculoperitoneal (VP) shunt. His condition did not improve during the 47 days of treatment with IV cefotaxime and meropenem. We achieved improvement in clinical presentation and CSF profile after three times of intraventricular gentamicin injection. The patient was discharged from the hospital with antiepileptic drugs. The second case was a six-month-old female patient with a history of neonatal meningitis complicated with hydrocephalus at one month of age, VP shunt at two months of age, followed by a methicillin-resistant coagulase-negative staphylococci (CoNS) shunt infection with ventriculitis after the shunt operation. CoNS ventriculitis recurred four weeks later. We failed to treat intractable methicillin-resistant CoNS ventriculitis with IV vancomycin for ten days, and thus intraventricular antimicrobial treatment was considered. Five times of intraventricular vancomycin administration led to improvement in clinical parameters. There were only neurological sequelae of delayed language development but no other major complications. Patients in these two cases responded well to intraventricular antibiotics, with negative CSF culture results, and were successfully treated for ventriculitis without serious complications.

• Journal of Korean society of Dental Hygiene
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• v.13 no.6
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• pp.933-939
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• 2013

Objectives : The purpose of this study is to examine the relationship between general characteristics and the intention of overseas employment and job satisfaction by Korean dental hygienists. Methods : We conducted a survey of 562 dental hygienists working in dental clinics nationwide. Collected data were analyzed by using the SAS(Version 9.2, SAS Institute, Cary, N.C.) package. $x^2$ test was used to determine the general characteristics of the subjects including job satisfaction level and intention to work abroad. Results : Old aged dental hygienists tended to work in the country rather than abroad(p<0.05). Higher job satisfaction was closely related to working hours, monthly income, social status, and stability of employment(p<0.05). Job satisfaction was concerned with intention to overseas employment. The main purpose of overseas employment included economic benefits(35.99%), self realization(26.75%), and improvement of working condition(21.66%) in the group of overseas employment(p<0.05). The obstacles to overseas employment were mastery of language proficiency(60.94%) and related information(21.89%) in those who want to work abroad. Conclusions : In order to increase the number of Korean dental hygienists for overseas employment, it is necessary to improve working competence and job satisfaction.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.4
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• pp.89-104
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• 2019

Purpose : The purpose of this study was to investigate the development of korean vowels by acoustically analyzing whether children produce Korean vowels differently according to their age and gender between ages 4 and 6. Methods : A total of 104 children aged 4~6 years (56 males and 48 females) participated in this study. The participants were classified as either 4, 5, or 6 years old. Vowel speech data was obtained by asking the subjects to pronounce meaningful words in which the vowel in question was located in the first syllable. Speech analysis was performed using the Multi-speech 3700 program. Results : Age, gender, and vowel being pronounced all had significant effects on intensity. There was significant decrease with increasing age, and the intensity was significantly higher in male children than female children. Neither age, gender, nor the vowel being produced affected the fundamental frequency. The fundamental frequency produced did not differ by age or gender. The first and second formants had considerable effect on age and vowels, significantly decreased with age, and did not have a gender difference. Conclusion : The results of this study showed that children aged 4~6 have similar anatomical structures, but that maturity of speech motor skills required to pronounce vowels was correlated with age. The results of this study can be used to evaluate children's speech and develop speech therapy programs.