• Herbal Formula Science
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• v.25 no.3
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• pp.391-412
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• 2017

Objective : In this study, we searched the experimental research about combined treatment of anticancer drug and herbal medicine for killing or inhibiting proliferation of Cancer cells searched in OASIS and KISS. This study aimed to analyze the experimental research paper about anticancer drug combined treatment with herbal medicine. Methods : We collected the research paper including killing or inhibiting proliferation of Cancer cells in OASIS and KISS using keyword anticancer drug with herbal medicine, tumor suppressor with herbal medicine, inhibition of Cancer with herbal medicine and combined treatment with herbal medicine. Assorting by cancer cells, we analyzed experimental results cancer cell viability, anticancer drug dosage, tumor weight and survival rate. Also, we checked the effects of herbal medicine on cancer and additive effect reducing side effect of anticancer drug. Results : Total 45 studies were selected. 38 studies reported combined treatment of anticancer drug and herbal medicine was more effective than only anticancer drug. The death of cancer cells was synergistically induced by the cotreatment of anticancer drug and herb extracts. The studies suggest that the cotreatment of anticancer drug and herb extracts could reduce side effect of anticancer drug. In addition, some studies reported cotreatment mechanism like apoptotic death signal processes. In combined treatment of anticancer drug and herb extracts, The expression of Fas/Fas L, Bax, Bcl2, Caspase-3 etc.. was markedly increased in cancer cells. Conclusions : Our results suggest that anticancer drug combined treatment with herbal medicine could be efficient for killing or inhibiting proliferation of cancer cells. However, this paper had some limitation as follows: First, collected studies have been published only for korean journal. Second, results of research and effects of combined treatment are not collected objectively. To solve these problems, more objective and balanced studies should be performed.

• Journal of Korean Medical classics
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• v.29 no.2
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• pp.91-119
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• 2016

Objectives : In this paper, the main objective is to analyze and evaluate Kim Gwangjin(金光鎭, 1885-1940)'s academical achievements of integration of eastern with western medicine and innovation of traditional medicine(TM, 漢醫). Methods : This paper is composed of two parts. First, analyzing Kim's medical book, the principle of Up and Down in Medicine(醫學升降法) by the way of text analysis and interpretation faithfully. Second, adding historical perspectives about his achievements. Results : Kim opened a clinic and practiced TM in Daegu, a city of Youngnam(嶺南) area of Korea, in 1924, and published the book in 1936. While Kim acknowledged the scientific results by western medicine and criticized the typical explanation of five viscera or qi circuits of TM, he clarified the treatment range for TM and provided his own interpretations of pathophysiology through the ups and downs of qi, without conflicting between western medicine and TM. Moreover, he critically follows the TM discourses of the most noted practitioner, Lee Gyoojoon(李圭晙), in the Youngnam area of the time. Conclusions : In the 1930s, although western medicine has become the new core orientation and has forced out TM to the districts, within the abyss of the districts, TM still maintained its strong presence.

• Korean Management Science Review
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• v.28 no.2
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• pp.93-103
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• 2011

This paper has aimed to identify marketing variables which affect physicians' prescription of drug. Based on a literature review this paper derives the three factors (indirect commercial source, direct commercial source, academic information source) of information sources that physicians rely on for medicines, the three factors (research supporting activity, marketing supporting activity, medicine information supporting activity) of promotion activities physicians prefer, and the four factors (indirect quality of medicine, direct quality of medicine, experience of using medicine, price and design of medicine) of prescription criteria physicians use. Then it investigates using canonical correlation analysis whether or not physicians' prescriptions are affected by the information sources, the promotion activities, and the type of physicians. From the canonical correlation analysis this paper derives the meaningful three canonical functions of prescription for drugs. The first function explains the prescription which is insensitive to marketing activities, the second function does the prescription which is sensitive to them, and the final function does the prescription which is not affected by them.

• The Journal of Internal Korean Medicine
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• v.44 no.5
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• pp.1071-1082
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• 2023

Objective: The purpose of this study is to report the efficacy of using Korean medicine treatment with cold hypersensitivity of the hands and feet with lumbar spinal herniated intervertebral disc. Case presentation: We used Korean medicine treatment (Gyejigabuja-tang, acupuncture) to treat a hospitalized patient with cold hypersensitivity of the hands and feet with lumbar spinal herniated intervertebral disc. To evaluate the treatment, we used the Numerical Rating Scale (NRS). The degree of cold hypersensitivity of the hands and feet was also evaluated using evaluation paper. The generic health status was measured using the European Quality of Life-5 Dimensions (EQ-5D) scale. The 31-year-old female underwent 13 days of inpatient treatment. Her pattern identification was that both hands and feet are cold (BiYangHeo) types. The treatments were herbal medicine and acupuncture. She took Gyejigabuja-tang for 13 days. She also received acupuncture for 20 minutes twice a day at LI11 (曲池), L14 (合谷), TE5 (外關) on her hands, LR3 (太衝), SP6 (三陰交), SP9 (陰陵泉) ST36 (足三里), GB41 (足臨泣) on Feet, GV4 (命門), GV3 (腰陽關), BL23 (腎兪), BL24 (氣海兪), BL25 (大腸兪), and BL26 (關元兪) on the low back. After 2 weeks of treatment, the NRS scale of her cold hypersensitivity of hands and feet symptoms dropped from NRS 7 to NRS 3, and her low back pain dropped from NRS 6 to NRS 3. Her cold hypersensitivity of hands and feet evaluation paper score decreased from 64 to 32, and her EQ-5D increased from 0.487 to 0.681. After the end of treatment, continued symptom improvements and no significant side effects were confirmed. Results: These findings suggest that Korean medical treatment (Gyejigabuja-tang, acupuncture) may be effective for treating cold hypersensitivity of hands and feet with lumbar spinal herniated intervertebral disc. The NRS, evaluation paper, and EQ-5D scores improved after treatment, with no side effects.

• Korean Journal of Oriental Medicine
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• v.16 no.1
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• pp.93-99
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• 2010

When researchers plan R&D projects, they usually use patent map or paper map for the objective decision-making, but in traditional korean medicine field, domestic patents and papers have been mainly proposed as results of many R&D projects, while most of patent or paper map tools support international patents and SCI papers, respectively. Therefore, as an alternative one KIOM constructed the project map which can provide the technology landscape for R&D project information in traditional korean medicine field. But the functions of the system is limited to the search and analysis with chart. So sophisticated analysis results are hard to get from the existing system. This research's goal is to upgrade the web based project map analysis system to provide researcher rich functionality and advanced analysis tools.

• Carbon letters
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• v.6 no.4
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• pp.255-256
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• 2005

In traditional Chinese medicine, some herbs are used after toasting or roasting. The process is called "Zhi Tan" in Chinese, which means charring, and the herbs after the treatment is called carbon medicine. Carbon medicine is widely used to arrest bleeding in traditional Chinese medicine. The paper introduces the records, development and applications of carbon medicine in ancient China. The earliest record found about carbon medicine was in the remains of Han dynasty (BC206-A.D.8). The paper also introduces the process of charring herbs and mechanism of carbon medicine in arresting bleeding. Calcium iron and tan released during the charring are believed as main factors for arresting bleeding, helped with porous surface structure of active carbon.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.4
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• pp.751-760
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• 2009

Yoon Gil-Young(1911-1987) was a frontier of the field of Traditional Korean Medical Physiology(TKMP) who was academically active since mid 1950s until early 1970s. He wrote several important papers and books. Among his writings, "A Study on the Methodology of Traditional Korean Medical Physiology", which was published serially in the "Korean Oriental Medical Journal" from June 1966 until March 1967, played an important role in establishing the contemporary TKMP and showed his academic stance on Traditional Korean Medicine(TKM). This review will evaluate this paper's contribution to the establishment of TKMP in historical context, summarize the unique characteristics of his understanding of TKMP by analyzing the text, and then based on those information, examine his view on TKMP and TKM. Historically, this paper was written in transition period from the traditional TKM knowledge system to the modernized one. Aim of this paper was to provide a methodology for establishing TKMP as a scientific knowledge system like that of the western medicine. Based on his study of Yin-Yang theory and theory of five circuits and six qi in Huangdi's Internal Classics, he suggested those theories as methods to observing life phenomena and systematizing the observations. And he regarded these methods as of great value in determining the unique characteristics of TKM compared to those of western medicine. Through re-reading this paper, it was found that he had pride and confidence in the methodology of TKM, and also that he thought in scientizing and modernizing TKM it was very important to understand and efficiently put in use the methodology of TKM. It was also found that his view on TKMP and TKM was pro modernization.

• Journal of The Association for Neo Medicine
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• v.1 no.2
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• pp.57-82
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• 1996

The policies of oriental medicine, changes of medical systems, development of oriental medical education and research activities of oriental medicine were reviewed in this paper from 1945 to 1995 and several opinions were suggested to relevant government authorities and doctors of oriental and western medicine. The history of oriental medicine had to come a long and winding road since the Political Reform in 1894. However, national effort of oriental medicine people in Korea has kept the oriental medicine as national medicine. It has been a misfortune that oriental and western medical doctors did not get along well each other. In this paper, the right direction of the medical systems for government were suggested together with timely roles of medical doctors of both oriental and western medicine. 1. Government should carry out reasonable and future-oriented medical systems. 2. Medical doctors of both oriental and western medicine should co-operate and try to promote mutual understanding. 3. Oriental medicine should be lectured in western medical college. 4. Medical researches of both oriental and western medicine should be carried out together.

• Journal of Korean Medical classics
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• v.25 no.3
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• pp.57-78
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• 2012

Objective: Although the government acknowledged Korean Medical Doctors as official health care providers since 1951, criticism regarding its modernity persisted. This paper focuses on the medical dispute between Korean and Western Medicine in 1950s risen from the problem of modernization of Korean Medicine. Method: This paper looked into the medical dispute between Korean and Western Medicine in 1950s through "EE LIM". "EE LIM" is a scholarly journal published by Korean Medical doctor Bae Won-Sik. Articles regarding the medical dispute between Korean and Western Medicine were selected, categorized and analyzed. Result: The main questions against Korean Medicine were: whether it was scientific or not, and whether there was a possibility of systematization. Several opinions were brought up on these issues. 1) Some people criticized Korean Medicine as being unscientific based on modern science. 2) Others emphasized the identity of Korean Medicine against the critics. 3) Another group of people wanted to study Korean Medicine using modern methods and obtain merits from both sides. Conclusion: The different understanding of the term 'science' led to diverse discussions on the direction of Korean Medicine's progression. The narrow meaning of science only considers Korean Medicine as an object of modern scientific and medical study. But if the meaning is broadened, containing empirical aspects, Korean Medicine can be included as a category of science based on its clinical utility.

• Korean Journal of Oriental Medicine
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• v.16 no.2
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• pp.43-55
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• 2010

Objective : There is a growing interest on Complementary and Alternative Medicine(CAM). But the term 'CAM' often causes confusion, for the perception of CAM is determined by how the relationship between CAM and Conventional Medicine is established. Methods : In this paper, we researched the concept of CAM through the change in the terminology and definition of CAM throughout history. Furthermore, we also analyzed related papers in Korea. Results : International studies show that the relationship between Conventional Medicine and CAM has become more cooperative. Meanwhile, in Korea, Korean Medicine is categorized as a type of Conventional Medicine, not CAM. Conclusion : Though Korean Medicine is included in Conventional Medicine in Korea, the research methodology is still restricted in ways of bio-medical science. Further study on the original research method of Korean Medicine is needed.