• Korean Journal of Medicinal Crop Science
• /
• v.16 no.1
• /
• pp.57-61
• /
• 2008

This experiment was carried out to search for changes of growth and pharmacological component contents by cultivation years in Artemisia capillaris. Percentage of ovenwintering in 1-year old was high as 95.3% but that in 2-years old was very low as 64.2%. Plant height was the highest in 2-years old among the treatments. By the way, number of stems and branches were shown wide difference by cultivation years, so those were the best in 3-years old. It was thought that 3-years old plants dispersed and used their nutrients by increasing branches. Fresh weight was the highest as 200.0 g in 3-years old, whereas weight of capitulum included scoparone, effective component, was the highest as 109.6 g in 2-years old and low as 96.4 g in 3-years old. In general components, crude protein and ash were more included in 1-year old and crude lipid and fiber were more included in 2 and 3-years old. Especially, content of crude fiber in stem was the highest in 3-years old. Pharmacological components were the most existed in capitulum of 2-years old, so contents of scoparone and capillarisin were 6.5 mg/g DW, 1.65 mg/g DW, respectively.

• The Korea Journal of Herbology
• /
• v.38 no.3
• /
• pp.1-10
• /
• 2023

Objective : Obesity in modern society has a significant impact on pathological, psychological and social problems. Therefore, many studies on obesity treatment using herbal extracts with fewer side effects have been conducted. This study was designed to investigate the effect of inhibiting fat accumulation in vitro in order to Mongolian medicinal plants find anti-obesity candidate among. Methods : We measured pancreatic lipase inhibitory activity in Mongolian medicinal plants extract. Cytotoxicity of these extracts was monitored in 3T3-L1 cells by MTT assay. In addition, the anti-obesity effects was confirmed at concentrations of 0.2, 0.1 and 0.05 mg/㎖ through Oil red O staining. Results : Among Mongolian medicinal plants, Rheum undulatum roots in September (RURS), Paeonia anomala L. (PAL), and Fragaria orientalis (FO) showed the highest pancreatic lipase inhibitory activity. As a result of the MTT assay, more than 80% was judged to be non-toxic, and the concentration was determined, and as a result of evaluating the lipid accumulation inhibitory effect, 6 types were selected as candidates. Conclusion : Based on these results, the top 7 species expected to be used as anti-obesity functional materials were selected. However, additional efficacy verification and mechanism of action need to be established in the future. So, it is expected that the medicinal plants verified through this will be used as functional materials for the prevention and treatment of obesity.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.16 no.2
• /
• pp.215-219
• /
• 2002

Over the past decade there has been a resurgence of interest in botanical products for their medicinal uses. This present study was designed to screen medicinal plants for the treatment of brain diseases such as Alzheimer's disease or aging. We tested the effects of the water extracts from 41 species medicinal plants on acetylcholinesterase (AChE) inhibition and antioxidant activity in vitro. Among them, Euodia rutaecarpa, Rubus coreanus, Achyranthes japonica, Morus alba, Salvia miltiorrhiza, Liriope platyphylla, and Rheum palmatum showed relatively AChE inhibition potency over 80%. Among the 7 medicinal plants investigated, E. rutaecarpa showed an 25%, 65%, and 93% inhibitions on AChE activity at 2.5, 12.5, and 25 ㎍/㎖ of the extract, respectively and was found to be one of most potent AChE inhibitor. The water extracts from 4 species (E. rutaecarpa, R. coreanus, A. iaponica, and M. alba) were tested on their antioxidant capacities using radical scavenging effect against ABTS/sup ㆍ+/. Among the 4 medicinal plants investigated, both R. coreanus and E. rutaecarpa showed significant antioxidant capacity. Therefore, E. rutaecarpa and R. coreanus are expected to ameliorate the clinical symptoms in Alzheimer's disease due to significant AChE inhibition and radical scavenging effect.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.23 no.1
• /
• pp.150-155
• /
• 1994

In order to evaluate the effect of the extracts of eidble and medicinalplant son the activation of immune cells, measurements were made by ELISA and radioimmunoassay on the degree of release for the tumor necrosis factor (TNF) and neopterin by the edible and medicinal plants in peripheral blood cells. The results of measurements of TNF in the supernatant cultured liquid showed nothing in t도 control which does not have any edible and medicinal plants. However, measurements of TNF 9pg/ml) in the samples are given as follows : 716.7 in lipopolysaccharide (LPS 1 g/ml), 465.2 Rheum plamatum L.m302.7 Sanguisorba offciinalis L. 818.2 Rubus coreanus M, 328.3 Terminalia chebula R., 426.6 AReca catechu L. 227.0 Eugenia caryophiliata T., 272.9 Ephedra sinica S., 30.1 Caesalpinia sappan L., 474.0 Chaenomeles japonica L., 396.0 Cornus officinalis S.in edible and medicinalplants. ENopterin (n mole/L) value showed below the check point in the control group, however, the values are 11.0 in LPS, and edible and medicinal plants, 5.3 Rheum palmatum L., 11.6 Eugenia caryophiliata T., 5.5 Ephedra sinica S., 4.5 Caesalpinia sappan L., 4.3 Chaenomelees japonica L.3.7 Cornus officinalis S. In order to find m RNA levels of Cytokines increased by edible and medicinal plants, total RNA was separated from mononuclear cells treated 5 hrs with Rubus coreanus M. and then administrated for RT-PCR. The considerable increases of the m RNA of TNF, IL-1 $\alpha$ and IL-6 were observed.

• Korean Journal of Medicinal Crop Science
• /
• v.16 no.1
• /
• pp.33-38
• /
• 2008

This study was carried out to reduce the number of chemical treatment by optimal apply for the disease and pest and obtain the basal data of environmental-friendly cultivation in Panax ginseng in 2006. The result by checking disease Incidence and pests fried in ginseng field of jeollabuk-Do was as follows. The kind of disease occurred in Jinan was 8 including Rhizoctonia solani, 7 with Botrytis cinerea in Jeongeup, and also 6 with Botrytis cinerea in Kochang within Jeollabuk-Do. It was required thorough disease control before the rainy season because the occurrence time was peaked around July. Also, the most serious disease in Jeollabuk-Do was Alternaria alternata, Botrytis cinerera, and Colletotrichum gloeosporioides. The actual harmful pests in ginseng field were Asusta despecta steboldiana and Holotrichia sp. and in other method using black light trap, Maladera orientalis, Ostrinia furnacalis, and Holotrichia morosa were mainly trapped.

• Nutrition Research and Practice
• /
• v.7 no.6
• /
• pp.510-518
• /
• 2013

This study aims to demonstrate the effect of farming technology on introducing medicinal plants (MP) and wild food plants (WFP) into a traditional agricultural system within peri-urban zones. Field investigations and semi-structured focus group interviews conducted in the Buhozi community showed that 27 health and nutrition problems dominated in the community, and could be treated with 86 domestic plant species. The selected domestic MP and WFP species were collected in the broad neighboring areas of the Buhozi site, and introduced to the experimental field of beans and maize crops in Buhozi. Among the 86 plants introduced, 37 species are confirmed as having both medicinal and nutritional properties, 47 species with medicinal, and 2 species with nutritional properties. The field is arranged in a way that living hedges made from Tithonia diversifolia provide bio-fertilizers to the plants growing along the hedges. The harvest of farming crops does not disturb the MP or WFP, and vice-versa. After harvesting the integrated plants, the community could gain about 40 times higher income, than from harvesting farming crops only. This kind of field may be used throughout the year, to provide both natural medicines and foods. It may therefore contribute to increasing small-scale crop producers' livelihood, while promoting biodiversity conservation. This model needs to be deeply documented, for further pharmaceutical and nutritional use.

• The Korea Journal of Herbology
• /
• v.27 no.3
• /
• pp.57-65
• /
• 2012

Objective : For the purpose of developing Korean herbology of the plants to Polyporaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article. Methods : The examined herbological books and research paper which published domestically and abroad. Results : 1. Polyporacease plants (raised in Korea) are devided into 31 classes with 59 species. Among them, 26 species in 19 classes were found serviceable, which indicates 44 % of all Polyporacease plants. 2. Among those 59 species, $Coriolus$ $Phellinus$ $Trametes$ includes 5 species. $Ganoderma$, a medicinal plant, includes 3 species. 3. Dividing the serviceable plants of Polyporacease, the fruit body family had the largest number; 25. 4. Out of plants Polyporacease, neutral taste plants was 17 species and sweet taste was 14 species. 5. Only 8 species of Polyporaceae plants were found to enterd into the spleen and heart. 6. 11 species were found to prevent cancer, 7 species were found to dispel wind-dampness and Alleviate edem antittusive and antasth matic. 7. There were no toxic species in the Plyporaceae. Conclusion : There were totaled to 31 genera and 59 species in Polyporaceae in Korea and among them medicinal plants are 19genera, 26 species, some 44% in total.

• The Journal of Korean Medicine
• /
• v.16 no.1 s.29
• /
• pp.475-498
• /
• 1995

For the purpose of developing Korean Herbalogy with the plants of Urticaceae which grow wild and is planted in Korea, the these and writings on herbalogy, from literature of successive generations, have been thoroughly investigative and the results obtained were as follows: 1. There were totaled 11 genera and 44 species in Korea and among them medecinal plants are 9 genera, 19 species, some 43% in total but the number of species may be added because of similar plants. 2. According to the oriental name which can be used for medical purpose, the medicinal plants beloning to the Urticaceae were classified as Herba 10, Radix 8, Folium 3, Cortex 1, Flos 1, Rhizoma 1. Thus it was noticed that Herba was the main kind. 3. According to sum of 44 species in Urticaceae they were classified into Boehemeria genera 18, Urtica genera 9, Pliea genera 5, Elastosma genera 3, Parietaria genera 2, Pellionia genera 2, Achudemia 1, Debregeasia genera 1, Girardinia genera 1, Laportea genera 1, Nanocnide genera 1 etc. Thus it was noticed that Boehemeria genera was the main kind, some 41% in total. 4. According to nature and flavour of medicinal plants, they were classified into cold, cool; 6 each, wormth, heat; 4 each, balance 3. Thus it was noticed that cold and cool is the main in nature and flavour of medicinal plants. 5. According to the Properties and Principal Curative action, they were classified into, clearing up heat and toxin 9, drugs for urination an removing abscess 7, drugs for circulating blood and hemostasis 7, drugs for expelling wind 5, drugs for comporting embryo 4, 6. Comparing to whole medicinal plants 44 kinds, toxic durgs include minor toxin were 2 kinds, 5% of the whole. Thus toxic durgs were rare. From this result, It was revealed that the plants for medical purpose in Urticaceae was 43% kinds of the whole, in which Herba was mostly abundunt, toxic plants were so rare that it will be used for clinical treatments more easily. It is considered that many clinical experiments and approaches must be continued to use widely.

• Food Science and Biotechnology
• /
• v.17 no.6
• /
• pp.1235-1239
• /
• 2008

To study the health promoting effects of medicinal plants, 30 medicinal plants commonly available in Korea have been evaluated for their antioxidant compounds and antioxidant and antiproliferative activities. Total polyphenolics and flavonoids in the methanolic extracts were measured by spectrophotometric methods and 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging activities and chelating effects have been determined for antioxidant activities. Moreover, the effects of medicinal plants on cell proliferation of intestinal (Caco-2) and pituitary (GH3) tumor cells were investigated using thiazolyl blue terazolium bromide (MIT) assay. The methanolic extracts of Pueraria thunbergiana and Artemisiae asiatria contained the highest total polyphenolic and flavonoid contents, respectively. P. thunbergiana exhibited the highest antioxidant activities. A. asiatria showed the strongest antiproliferative activity against Caco-2 and Ponciruc trifoliata Rafin and Lophathrum gracile Bronghiart exhibited the highest activities against GH3. Although there was positive correlation between ABTS radical scavenging activity and polyphenolic contents ($R^2=8189$), no relationship was found between antiproliferative and antioxidant activities.

• Korean Journal of Korean Medical Institute of Dermatology and Aesthetics
• /
• v.1 no.1
• /
• pp.91-97
• /
• 2005

(1) Objectives: To discover natural skin-lightening agents, we have evaluated the inhibitory activity of EtOH extracts from 20 medicinal plants against mushroom tyrosinase. (2) Methods: Tyrosinase activity was determined by the dopachrome method using L-tyrosine as the substrates. (3) Results: Of the plant extracts tested, the extracts of 4 plants, Albizzia julibrissin, Curcuma longa, Anethum graveolens and Sophora flavescens, exhibited potent inhibitory activity (> 50%) in mushroom tyrosinase assay. Four plant extract, extracts of Agrimonia pilosa, Paeonia moutan, Magnolia obovata and Eugenia caryophyllata also showed relatively strong inhibitory (> 40%) against mushroom tyrosinase. (4) Conclusion: These active medicinal plants may be useful for the development of skin-whitening agents. Since the active medicinal plants may contain effective tyrosinase inhibitors even more than kojic acid, further study to identify the active constituents from the plants is expected.