• 대한수의학회지
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• 제41권3호
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• pp.413-419
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• 2001

개에서 실험적으로 편측성 신수종증을 유발한 후, 이오헥솔-에탄올 용액을 신장동맥내로 주입하여 신수종증이 유발된 신장으로서의 혈류를 차단하는 신동맥 색전술을 실시한 후, 컬러 도플러 초음파상을 이용하여 색전술이 실시된 신수종증의 신장과 반대편 정상신장을 평가하고자 본 실험을 실시하였다. 수뇨관 결찰 후, 유발 전에 비하여 혈관저항지수가 4일, 9일, 17일째에 유의적으로 증가하였으며, BUN, creatinine, ALT, calcium, phosphorus는 변화하지 않았다. 이를 통하여 12두의 개에서 요관 결찰 17일째에 편측성 수신증이 유발되었음을 확인할 수 있었다. 신장동맥 색전술은 7두의 신수종증이 유발된 신장측의 신장동맥에 대퇴동맥을 통하여 선택적으로 카테터를 삽입한 후 이오헥솔-에탄올 용액을 주입하였으며, 시술 중 심전도, 산소포화도, 체온 맥박, 호흡수는 모두 정상범위에 있었다. 신장동맥 색전술 후 사망한 개체는 없었으며, 색전물질의 유출로 인한 부작용도 관찰할 수 없었다. 색전술 실시 후 시행한 칼라도플러 초음파 검사에서는 7두 모두에서 실험 전 기간에 걸쳐 색전된 신장에서 혈관신호를 관찰할 수 없었으나, 색전술을 실시하지 않은 5두에서는 신장내에서 혈관신호를 관찰할 수 있었다. 그리고 색전술을 실시한 7두의 정상신장의 평균 혈관저항지수는 정상견의 혈관저항지수와 유의적인 차이가 없음을 확인할 수 있었다. 칼러 도플러 초음파 검사법은 개의 수신증에 실시한 신장동맥 색전술 후의 신장동맥의 재맥관화를 평가할 수 있는 간편하며, 비침습적인 검사법으로 사료된다.

• 대한수의학회지
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• 제47권3호
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• pp.325-331
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• 2007

The present study was performed to clarify the recovery effect of polyacetylene constituents from Acanthopanax senticosus ethanol extracts on $CCl_4$-induced acute hepatic injury in dogs. Sixteen clinically healthy dogs were divided into the control group (six dogs), and experimental group I (three dogs), II (three dogs) and III (four dogs). Acute hepatic injury was induced by single intraperitoneal injection of 1 ml/kg $CCl_4$ solution ($CCl_4$ : olive oil = 1 : 1) after sterilization. The control group was orally administered with 10 ml of corn oil, and experimental groups I, II and III were orally administered with extracts of A. senticosus at the dose of 5, 10 and 30 mg/kg in 10 ml corn oil for seven consecutive days at 24 h after $CCl_4$ injection. We assessed changes occurring in serum ALT, AST and GGT activities on the pre, day 0, day 1, day 2, day 3, day 5 and day 7, together with the histopathological findings. In experimental group I, the significant changes in serum ALT activities were found on day 5 (p<0.05) and day 7 (p<0.05), compared with those in the control group. However, significant differences were not found in the changes of serum AST and GGT activities. In experimental group II, significant changes were found on day 2 (p<0.05), day 3(p<0.05), day 5 (p<0.05) and day 7 (p<0.05) in serum ALT activities, on day 1 (p<0.05) in serum AST, and on day 2 (p<0.05) and day 3 (p<0.05) in serum GGr activities, respectively. In experimental group III, the changes in serum ALT, AST and GGT activities were not significant. In the histopathological evaluation, experimental group I and II showed much improvement, while experimental group III became worse when compared with the control group. Based on the results of the present study, it was concluded that low dose (below 10 mg/kg) administration of polyacetylene constituents from A. senticosus ethanol extracts was effective for recovery of acute hepatic injury induced by $CCl_4$ in dogs.

• 대한수의학회지
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• 제20권2호
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• pp.175-178
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• 1980

Normal values of serum electrolytes were determined for adult 36 females and 18 males, 1 to 6 years old, of Jindo dogs. The mean values, standard deviation and rangEs of sodium, potassium, chloride, calcium and inorganic phosphorus were studied and data analyzed to determine whether differences existed between the values of female and those of male dogs. The results obtained in this study were as follows: 1. The mean value of serum sodium was $143{\pm}1.5mEq/liter$, ranged from 138mEq/liter to 152 mEq/liter. The mean values for the females and males were $144{\pm}2.0mEq/liter$ and $142{\pm}1.7mEq/liter$, respectively. They showed that the female dogs had a tendency toward higher values than the male dogs, but no significant sex-related differences were observed. 2. The mean value of serum potassium was $4.6{\pm}0.2mEq/liter$, ranged frem 3.5mEq/liter to 6.0mEq/liter. The mean values for the females and males were $4.7{\pm}0.4mEq/liter$ and $4.5{\pm}0.3mEq/liter$. They showed that the female dogs had a tendency toward higher values than the male dogs, but sex differences were not found to be significant. 3. The mean value of serum chloride was $103{\pm}3.0mEq/liter$ ranged from 95mEq/liter to 117mEq/liter. The mean values for the females and males were $103{\pm}3.2mEq/liter$ and $103{\pm}3.3mEq/liter$, no sex differences showed. 4. The mean value of serum calcium was $5.2{\pm}0.1mEq/liter$ ranged from 4.7mEq/liter to 5.8mEq/liter. The mean values for the females and males were $5.4{\pm}0.1mEq/liter$ and $5.2{\pm}0.09mEq/liter$ respectively, no significant sexd iffere-nces were observed. 5. The mean value of serum inorganic phosphorus was $4.3{\pm}0.7mg/100ml$, ranged from 2.5mg/100ml to 5.8mg/100ml. The mean values for the females and males were $4.3{\pm}0.9mg/100ml$ and $4.1{\pm}0.8mg/100ml$, respectively, no sex differences showed.

• 한국치위생학회지
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• 제21권4호
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• pp.337-348
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• 2021

연구목적: 본 연구는 개 치주염 평가에서 MiriChek^TM Oral Bacter test kit의 임상적 유용성을 판단하기 위해 실시하였다. 연구방법: 개 61두를 공시하여 품종, 연령(개월), 성별, 체중, 질병 유무, 임상적 치주염 단계를 수의 임상 진단 후 상악 왼쪽 전구치의 치태를 채취하여 MiriChek^TM Oral Bacter test kit를 이용하여 진단검사를 수행하였다. 연구결과: 대상 개 61두 중 건강한 개는 31두, 치주염 개는 30두였고, 치주염은 젊은 개보다 나이 든 개에게서 더 흔하게 나타났다. MiriChek^TM Oral Bacter test kit의 양성 평균 73.3%, 음성 평균 80.7%의 민감도를 보였고, 치주염의 심각도와 높은 상관관계를 확인하였으며, 그 결과 MiriChek^TM Oral Bacter test kit는 개 치주염 평가에 유용한 진단검사 방법임을 확인하였다. 결론: MiriChek^TM Oral Bacter test kit와 같은 새로운 진단 보조 기구의 활용은 개에게서 발생하는 치주질환 진단의 신뢰성과 정확성을 높일 것으로 판단된다.

• 한국임상수의학회지
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• 제30권1호
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• pp.1-4
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• 2013

본 연구는 개에서 주요 정형외과 수술에 따른 전신 산화 스트레스 상태를 평가하였다. 16 마리의 골절이나 사지의 탈구 질환을 포함하는 환축을 대상으로 연구를 실시하였고 모든 환축은 골절이나 탈구의 치료를 위해 다양한 정형외과 수술을 받았다. 수술 후 혈장 총 산화상태(total oxidant status, TOS) 및 산화스트레스 지수(oxidative stress index, OSI)에서 유의적인 증가가 확인되었다. 수술 후 혈장 총 항산화상태(total antioxidant status, TAS)에서 유의적인 감소를 확인하였다. 본 연구를 통해 정형외과 수술외상에 따른 혈장 내 총 산화 및 항산화 상태가 산화스트레스와 관련 있음을 확인 할 수 있었다.

• 한국임상수의학회지
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• 제21권3호
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• pp.302-308
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• 2004

Sixty-six dogs diagnosed with cystolithiasis at animal clinics in the Busan area between April 2002, and April 2003, were reviewed. The chemical analysis of cystoliths from 66 dogs indicated that the predominant mineral component was struvite (45 dogs), calcium oxalate (14 dogs), or urate (6 dogs). Animals affected with struvite were grouped into four (s-1; struvite only, s-2; struvite mixed with lesser quantities of calcium oxalate or ammonium urate, s-3; nuclei and lamination, s-4; struvite nucleus surrounded by other minerals), with calcium oxalate into six(o-1; calcium oxalate monohydrate only, o-2; calcium oxalate dihydrate only, o-3; combination of calcium oxalate monohydrate and dihydrate, o-4; calcium oxalate nucleus surrounded by other minerals, o-5; 100% calcium oxalate monohydrate nucleus surrounded by 100% calcium oxalate dihydrate, o-6; mixed calcium oxalate monohydrate nucleus surrounded by mixed calcium oxalate dihydrate), and with urate into two(u-1; ammonium acid urate only, u-2; ammonium acid urate mixed with lesser quantities of other minerals). In this study, the numbers of 4 groups of struvite were (s-1; 10, s-2; 9, s-3; 21, s-4; 5), 6 groups of calcium oxalate were (o-1; 0, o-2; 1, o-3; 2, o-4; 3, o-5; 2, o-6; 6), and 2 groups of urate were (u-1; 6, u-2; 0). The data from each group was analyzed and compared. Shih Tzu(14 cases), Yorkshire terrier(10 cases), mixed-breed(10 cases) and Miniature schnauzer(7 cases) were more frequently affected than the other breeds. Females(40 cases) were affected more than males(26 cases). Twenty-nine dogs had cystoliths associated with a bacterial urinary tract infection, and uroliths tended to recur. We conclude eradication of urinary infection along with appropriate food (e.g. prescription diet) with client compliance should help in reducing the incidence or severity of the disease.

• 한국임상수의학회지
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• 제25권4호
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• pp.236-240
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• 2008

부갑상샘 호르몬 (PTH)은 칼슘과 무기인의 수송을 조절한다. 속발성 부갑상샘 기능항진증은 대개 만성신부전에서 발생하고, 이는 개와 고양이에 있어서 CRF의 일반적인 합병증이다. 신부전을 갖는 21마리의 개가 본 연구에 사용되었다. 공시동물로부터 채혈한 혈액 중 칼슘 (Ca),무기인 (iP), PTH의 농도를 측정하여 칼슘과 무기인의 비율에 따라 두 군으로 분류하였다 (Ca / iP $\leq$ I; 그룹 1, Ca/ip $\geq$ 1.5; 그룹 II). 성과 연령 사이에 부갑상샘 호르몬 수준은 유의성 있는 차이가 없었다. 두 군 사이에 부갑상샘 호르몬 수준과 Ca/P의 비율에는 유의성 (p<0.0001)있는 차이가 나타났다. 결론적으로, 칼슘과 무기인의 비율은 신부전을 갖는 개에서 부갑상샘 호르몬 수준을 예측하기 위한 지표로 이용될 수 있을 것으로 생각된다.

• 한국임상수의학회지
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• 제28권1호
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• pp.173-178
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• 2011

Homeopathic Pulsatilla 30C was evaluated in 4 clinical cases of ophthalmic complications with concomitant separation anxiety in dogs. Separation anxiety in dogs is excessive anxiety regarding to the separation from owners and is one of the most common behavioral problems in dog. In addition, ocular diseases is sometimes related with abnormal behaviors. Holistic approach is good alternative method to treat dogs with physical problem associated behavior problem. Homeopathy is one of the complementary and alternative medicines and bases on healing of patients themselves which includes mind healing, not the disease itself. Among the material medical remedy of homeopathy, the Pulsatilla is used as homeopathic remedy for ocular problems, earache, cough, cold, and anxiety from lost attention. These case studies described the successful treatment of ocular diseases and separation anxiety by application of Pulsatilla 30C as homeopathy in 4 dogs. During the homeopathy, these dogs did not receive any other treatments, and were performed the physical exam to check the ocular problems. These dogs were completely cured of physical and behavior problem within 10 days. On following up, any clinical signs were not observed at one month after the last therapy. In addition, as from the treatment the anxiety problem of patients has been much better improved. According to these case studies, we know that an application of homeopathic remedy may be useful therapeutic choice to treat both problems of physical and behavior.

• 한국임상수의학회지
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• 제26권1호
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• pp.62-68
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• 2009

A diaphragm is a musculotendinous partition that separates abdominal and thoracic organs and assists in ventilation. Three dogs were presented after being hit by a car, and one dog was presented with the history of respiratory problems including intermittent dyspnea and coughing. Survey thoracic radiography, positive contrast celiography and sonography revealed traumatic diaphragmatic hernia in three dogs and congenital peritoneopericardial diaphragmatic hernia in one dog. In three dogs including a dog with congenital peritoneopericardial diaphragmatic hernia, herniorrhaphy was performed. Among the three dogs underwent surgery, two dogs with traumatic diaphragmatic hernia recovered uneventfully. However the dog with congenital peritoneopericardial diaphragmatic hernia died from pulmonary edema at 2 days after surgery. Positive-contrast ceilography and ultrasonography provides to investigate the integrity of the diaphragm. Chronic diaphragmatic hernia and concurrent injuries are considered as prognostic factors.

• 한국임상수의학회지
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• 제34권6호
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• pp.454-458
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• 2017

A Maltese (case 1) and a Pomeranian (case 2) presented with acute right and left hind limb weight-bearing lameness. On physical examination, they exhibited severe pain and crepitus on the coxofemoral joint of affected hind limb. In addition, decreased thigh girth measurements were noted compared with the opposite leg. Radiological exam revealed necrotic areas in the femoral head of affected hind limb. These dogs were diagnosed with Legg-$Calv{\acute{e}}$-Perthes disease (LCPD). The dogs underwent micro total hip replacement (THR). After surgery, at 3 years (case 1) and 7 months (case 2), both dogs recovered normal activity. The thigh girth and lameness scores were apparently improved in the affected limbs of both dogs. No complications of prosthesis implants, such as loosening, were noted. The clinical outcomes of these cases indicate that dogs with LCPD can be successfully treated with micro THR and have a good prognosis immediately after surgery.