Canine Cystolithiasis in Busan : Analysis of the Architecture and Composition of Cystoliths: Review of 66 Cases(2002-2003)

부산지역에서 발생한 개의 방광결석증: 66례 결석의 구조와 성분의 분석(2002-2003)

  • 김은정 (경상대학교 수의과대학 동물의학연구소) ;
  • 이희천 (경상대학교 수의과대학 동물의학연구소) ;
  • 이효종 (경상대학교 수의과대학 동물의학연구소) ;
  • 장홍희 (경상대학교 수의과대학 동물의학연구소) ;
  • 이용훈 (오클라호마 수의과대학) ;
  • 연성찬 (경상대학교 수의과대학 동물의학연구소)
  • Published : 2004.09.01

Abstract

Sixty-six dogs diagnosed with cystolithiasis at animal clinics in the Busan area between April 2002, and April 2003, were reviewed. The chemical analysis of cystoliths from 66 dogs indicated that the predominant mineral component was struvite (45 dogs), calcium oxalate (14 dogs), or urate (6 dogs). Animals affected with struvite were grouped into four (s-1; struvite only, s-2; struvite mixed with lesser quantities of calcium oxalate or ammonium urate, s-3; nuclei and lamination, s-4; struvite nucleus surrounded by other minerals), with calcium oxalate into six(o-1; calcium oxalate monohydrate only, o-2; calcium oxalate dihydrate only, o-3; combination of calcium oxalate monohydrate and dihydrate, o-4; calcium oxalate nucleus surrounded by other minerals, o-5; 100% calcium oxalate monohydrate nucleus surrounded by 100% calcium oxalate dihydrate, o-6; mixed calcium oxalate monohydrate nucleus surrounded by mixed calcium oxalate dihydrate), and with urate into two(u-1; ammonium acid urate only, u-2; ammonium acid urate mixed with lesser quantities of other minerals). In this study, the numbers of 4 groups of struvite were (s-1; 10, s-2; 9, s-3; 21, s-4; 5), 6 groups of calcium oxalate were (o-1; 0, o-2; 1, o-3; 2, o-4; 3, o-5; 2, o-6; 6), and 2 groups of urate were (u-1; 6, u-2; 0). The data from each group was analyzed and compared. Shih Tzu(14 cases), Yorkshire terrier(10 cases), mixed-breed(10 cases) and Miniature schnauzer(7 cases) were more frequently affected than the other breeds. Females(40 cases) were affected more than males(26 cases). Twenty-nine dogs had cystoliths associated with a bacterial urinary tract infection, and uroliths tended to recur. We conclude eradication of urinary infection along with appropriate food (e.g. prescription diet) with client compliance should help in reducing the incidence or severity of the disease.

Keywords

References

  1. Domingo-Neumann RA, Ruby AL, Ling GV, Schiffman PS, Johnson DL. Ultrastructure of selected struvite-containing urinary calculi from dogs. Am J Vet Res 1996; 57: 1274-1287
  2. Finco DR, Rosin E, Johnson KH. Canine urolithiasis: A review of 133 clinical and 23 necropsy cases. J Am Vet Med Assoc 1970; 157: 1225-1228
  3. Funaba M, Hashimoto M, Yamanaka C, Shimogori Y, lriki T, Ohshima S, Abe M. Effects of a high-protein diet on mineral metabolism and struvite activity product in clinically normal cats. Am J Vet Res 1996; 57: 1726-1732
  4. Lekcharoensuk C, Osborne CA, Lulich JP, Pusoonthornthum R, Kirk CA, Ulrich LK, Koehler LA, Carpenter KA, Swanson LL. Associations between dietary factors in canned food and formation of canine calcium oxalate uroliths in dogs. Am J Vet Res 2002; 63: 163-169 https://doi.org/10.2460/ajvr.2002.63.163
  5. Lekcharoensuk C, Osborne CA, Lulich JP, Pusoonthornthum R, Kirk CA, Ulrich LK, Koehler LA, Carpenter KA, Swanson LL. Associations between dry dietary factors and canine calcium oxalate uroliths. Am J Vet Res 2002; 63: 330-337 https://doi.org/10.2460/ajvr.2002.63.330
  6. Lulich JP. Postsurgical recurrence of calcium oxalate uroliths in dogs. J Vet Int Med 1992; 6: 119-124
  7. Osborne CA, Bartges JW. Canine urolithiasis. In: Small animal clinical nutrition, 4th ed. Marceline : Walsworth Publishing Co. 2000: 605-680
  8. Sperrin MW, Rogers K. The architecture and composition of uroliths. Br J Urol 1998; 82: 781-4 https://doi.org/10.1046/j.1464-410X.1998.00851.x
  9. Stevenson AE, Markwell PJ. Comparison of urine composition of healthy Labrado Retrievers and Miniature Schnauzers. Am J Vet Res 2001; 62: 1782-1786 https://doi.org/10.2460/ajvr.2001.62.1782