• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2001.09a
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• pp.184-187
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• 2001

This study presents procedure and analysis method for not well known slug interference tests. Results of the slug interference tests were compared with those of pumping and recovery tests and conventional slug tests.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.12
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• pp.1521-1527
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• 2004

Thermocapillary migration of a liquid slug is caused by temperature difference between the ends of a slug. The temperature difference induces the difference of the surface tension coefficient and consequently of capillary pressure between the ends of the slug. Presently available model to predict a velocity of thermocapillary migration adopts the Poiseuille equation which is valid only for a very long slug and neglects the shear stress near the contact line. In the present study, a new model has been developed to consider the shear stress near the contact line so that it can be applied to slugs or drops of general configuration. The experiments using mineral oil with the length to diameter ratio being 10 and a glass capillary were performed. It was found that the liquid slug began to move upon overcoming contact angle hysteresis when the temperature difference reached 35$^{\circ}C$. The results indicate that the new model well predicts the velocity of the liquid slug.

• Journal of dental hygiene science
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• v.17 no.5
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• pp.433-438
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• 2017

Relative to its incidence, oral cancer has serious negative social effects. The exact causes of oral cancer have not been clarified, but many studies have implicated smoking and drinking. However, the fundamental mechanism of oral cancer causation has yet to be elucidated. Lysophosphatidic acid (LPA) augments epithelial mesenchymal transition (EMT) and development of various cancer cells. However, a detailed mechanistic explanation for LPA-induced EMT and the effects of EMT-promoting conditions on oral squamous cell carcinoma development remain elusive. In the present study, a quantitative reverse transcription polymerase chain reaction was used to analyze TWIST1, Slug, E-cadherin, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) transcript expression. Immunoblotting was used to analyze TWIST1, Slug, E-cadherin, and GAPDH protein expression. siRNAs were used to silence TWIST1 and Slug transcript expression. A matrigel-coated in vitro invasion insert was used to analyze oral cancer cell invasion. The results of the present study show that the expression levels of TWIST1 and Slug, which are EMT factors, were increased by LPA treatment in YD-10B oral squamous cell carcinoma. Conversely, E-cadherin expression was significantly reduced. In addition, transfection of the cells with TWIST1 and Slug siRNA strongly inhibited LPA-induced oral cancer cell invasion. The present study shows that TWIST1 and Slug mediate LPA-induced oral cancer cell EMT and invasiveness. The present study confirmed the mechanism by which LPA promotes oral cancer cell development, with TWIST1 and Slug providing novel biomarkers and promising therapeutic targets for oral cancer cell development.

• Transactions of Materials Processing
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• v.24 no.6
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• pp.425-430
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• 2015

In the current paper, the effects of initial slug design on the earring of an Al rectangular battery case manufactured by impact extrusion were studied. During impact extrusion, non-uniform metal flow between the long and the short sides of the battery case leads to earring, which is subsequently trimmed. Process parameters such as friction, aspect ratio of the battery case, the die shape and the forming temperature tend to induce earring because they cause greater non-uniform metal flow. Large aspect ratio of the battery case and high friction between slug and die can greatly affect the earring of a rectangular battery case. To make a rectangular battery case without earring, it is necessary to control metal flow uniformly during impact extrusion. One of the ways to reduce the earring is to control the metal flow of slug at the initial upsetting stage. To analyze the effects of the initial slug design on earring, FE analysis was conducted using DEFORM 3D. Two types of initial slug designs were evaluated where volume was removed along either the width or thickness directions. The results show that the initial slug design can be effective in adjusting the uniformity of metal flow.

• Journal of the Korean Society of Groundwater Environment
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• v.7 no.2
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• pp.89-96
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• 2000

Slug tests are the most widely used field method for quantification of hydraulic conductivity of porous media. Well recovery is affected by well casing, borehole radii, screened length, hydraulic conductivity, and specific storage of porous media. In this study, a new slug tests model was developed through finite element approximation and the validity and usefulness of the model were tested in various ways. Water level fluctuation in a well under slug test and cons-equent groundwater flow in the surrounding porous medium were appropriately coupled through estimation of well-flux using an iteration technique. Numerical accuracy of the model was verified using the Cooper et al. (1967) solution. The model has advantages in simulations for monitored slug tests, partial penetration, and inclusion of storage factor. Volume coverage of slug tests is significantly affected by storage factor. Magnitude and speed of propagation of head changes from a well increases as storage factor becomes low. It will be beneficial to use type curves of monitored head transients in the surrounding porous formation for estimation of specific storage. As the vertical component of groundwater flow is enhanced, the influence of storage factor on well recovery decreases. For a radial-vertical flow around a partially penetrated well, deviations between hydraulic estimates by various methods and data selection of recovery curve are negligible on practical purposes, whereas the deviations are somewhat significant for a radial flow.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.220-228
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• 2008

In constructing a slurry trench cutoff wall, a thin but relatively impermeable layer called filter cake can be formed on the excavation surface. The filter cake significantly influences the result of slug test analysis in the cutoff wall. This study is to examine the effect of filter cake on evaluating in situ hydraulic conductivity of the vertical cutoff wall along with slug test analyses. The numerical program Slug_3D was modified to take filter cake into account in the slug test simulation. With consideration of filter cake, the type curve method and the modified line-fitting method were used to reanalyze the case study taken from a landfill site. The previous results achieved by Choi and Daniel (2006b) without consideration of filter cake have been compared with the results in this study. The considerable difference between the two results shows the necessity of considering the filter cake in practice.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.6 s.237
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• pp.671-686
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• 2005

The transient nature and complex geometries of two-phase gas-liquid flows cause fundamental difficulties when measuring flow velocity using an electromagnetic flowmeter. Recently, a current-sensing flowmeter was introduced to obtain measurements with high temporal resolution (Ahn et al.). In this study, current-sensing flowmeter theory was applied to measure the fast velocity transients in slug flows. The velocity fields of axisymmetric gas-liquid slug flow in a vertical pipe were obtained using Volume-of-Fluid (VOF) method, and the virtual potential distributions for the electrodes of finite size were also computed using the finite volume method for simulating slug flow. The output signal prediction for slug flow was carried out from the velocity and virtual potential (or weight function) fields. The flowmeter was numerically calibrated to obtain the cross-sectional liquid mean velocity at an electrode plane from the predicted output signal. Two calibration parameters are proposed for this procedure: a flow pattern coefficient and a localization parameter. The flow pattern coefficient was defined by the ratio of the liquid resistance between the electrodes for two-phase flow with respect to that for single-phase flow, and the localization parameter was introduced to avoid errors in the flowmeter readings caused by liquid acceleration or deceleration around the electrodes. These parameters were also calculated from the computed velocity and virtual potential fields. The results can be used to obtain the liquid mean velocity from the slug flow signal measured by a current-sensing flowmeter.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.1951-1956
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• 2004

The transient nature and complex flow geometries of two-phase gas-liquid flows cause fundamental difficulties when measuring flow velocity using an electromagnetic flowmeter. Recently, a current-sensing flowmeter was introduced to obtain measurements with high temporal resolution (Ahn et $al.^{(1)}$). In this study, current-sensing flowmeter theory was applied to measure the fast velocity transients in slug flows. To do this, the velocity fields of axisymmetric gas-liquid slug flow in a vertical pipe were obtained using Volume-of-Fluid (VOF) method and the virtual potential distributions for the electrodes of finite size were also computed using the finite volume method for the simulated slug flow. The output signal prediction for slug flow was carried out from the velocity and virtual potential (or weight function) fields. The flowmeter was numerically calibrated to obtain the cross-sectional liquid mean velocity at an electrode plane from the predicted output signal. Two calibration parameters are required for this procedure: a flow pattern coefficient and a localization parameter. The flow pattern coefficient was defined by the ratio of the liquid resistance between the electrodes for two-phase flow with respect to that for single-phase flow, and the localization parameter was introduced to avoid errors in the flowmeter readings caused by liquid acceleration or deceleration around the electrodes. These parameters were also calculated from the computed velocity and virtual potential fields. The results can be used to obtain the liquid mean velocity from the slug flow signal measured by a current-sensing flowmeter.

• Journal of the Korean Society of Visualization
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• v.18 no.3
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• pp.116-121
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• 2020

In this study, a single-phase analysis of droplet slug with different contact angles was performed based on the visualization of experimental results. Droplet slug - flowing between gases in a hydrophobic mini channel - moves with a triple contact line without a gas liquid film on the wall. The results show that the rotational flow inside the droplet occurred; this was compared and verified with the results of two-phase analysis. The pressure field shows pressure rise at the front and rear ends. The effective length - the section that satisfies the laminar flow condition - became shorter as the droplet velocity increased. The Choi's correlation for the effective length agrees with this analysis results with a slight difference. This difference is judged as the difference in the contact angle of the slug model.

• Journal of the Korean Geotechnical Society
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• v.24 no.11
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• pp.121-131
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• 2008

In constructing a slurry trench cutoff wall, bentonite-water slurry is used to secure the stability of sidewalls during excavation before the wall is completed by backfilling. Unexpectedly, a thin but relatively impermeable layer called filter cake can be formed on the excavation surface, which significantly influences the result of slug test analysis in the cutoff wall if not considered. This study is to examine the effect of filter cake on evaluating hydraulic conductivity of the vertical cutoff wall through slug test analysis with the aid of the verified numerical program Slug_3D. The no-flux boundary conditions were adopted in Slug_3D to simulate the filter cake on the interface between the wall and the natural soil. A new set of type curves were built for applying the type curve method. New modification factors were obtained for using the modified line-fitting method. With consideration of filter cake, the type curve method and the modified line-fitting method were adopted to reanalyze the case study taken from EMCON (1995). The previous results achieved by Choi and Daniel (2006) without consideration of filter cake were compared with the present results obtained in this paper. The comparison emphasizes the necessity of considering filter cake when analyzing slug test results in vertical cutoff walls.