• 대한한의학원전학회지
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• 제27권3호
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• pp.155-166
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• 2014

Objectives : Many keyboarding staff are required for compositional herb data entry from ancient documents. It's the most difficult thing to build DB. So, we have studied to solve this problem. Methods : We have used Windows 7 and Access2013 for automatic extraction compositional herb in the Taipinghuiminhejijufang(太平惠民和劑局方). First of all, we have made synonyms list of herbs and list of herb volumes notation. And than we have analyzied order of arrangements between names of herb and notations of herb volume. Results : We have analyzied a part of prescriptions in the Taipinghuiminhejijufang(太平惠民和劑局方) (519 prescriptions). After 91 seconds, we can complete automatic extraction of compositional herb from 519 prescriptions. Conclusions : If we can analyzie order of arrangements between names of herb and notations of herb volume, we can automatically extract compositional herb of prescription from ancient documents.

• 한국의사학회지
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• 제28권1호
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• pp.53-60
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• 2015

Objectives : This is what tries to study irregular pairs between five viscera and five tatstes. And than tries to make convincing explanation. Methods : We analysed "SuWen ZangQiFaShiLun素問 藏氣法時論", "YiXueQiYuan醫學啓源", "TangYeBenCao湯液本草", "BenCaoGangMu 本草綱目" and "FuXingJueZangFuYongYaoFaYao輔行訣臟腑用藥法要". We found difference and similarities between these books. Result & Conclusions : "YiXueQiYuan", "TangYeBenCao", "BenCaoGangMu" inherit pairs between five viscera and five tatstes from "ZangQiFaShiLun". "YiXueQiYuan" had added examples of herbs to "ZangQiFaShiLun". "TangYeBenCao" had added examples of priscriptions to "ZangQiFaShiLun". "BenCaoGangMu" had added examples of herbs to "ZangQiFaShiLun". But new pairs between five viscera and five tatstes had suggested in the "FuXingJueZangFuYongYaoFaYao". We think that the new pairs are more logical than the others.

• 동의생리병리학회지
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• 제18권2호
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• pp.359-370
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• 2004

Before the current western medicine was spreaded out in the world as the main stream, each country had treated diseases with the medicine of their own and the traditional medical books, which are so characteristic, are handed down. Considering the earnest assignment to do in Korean medical of this age and one of the tendencies of medical circles in the world is putting together the current medicine with the traditional medicine, the production and spread of the classification system for the technical books which is contained the characteristic of traditional chinese medicine, the present condition of modern chinese medicine, and the future of it, must be settled without delay. The classification system for oriental medicine section developed in the range of the simple system before the time of flowering, since then the western medicine had grew as the main current in medicine in Korea. But until now the rational and realistic classification system based on the changeable time isn't be established, so setting up one of the classification systems for medicine section, it is classified according to the principle of classification system for medicine section. Hereupon, the result was made after researching the changes of modern classification system for korean and studying on the changes of classification system for oriental medicine section of the Korean decimal classification.

• 대한핵의학회지
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• 제37권5호
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• pp.288-300
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• 2003

목적: ${H_2}^{15}O$ PET의 정량화를 위하여 1-조직 구획모델이 쓰이며, 뇌혈류와 조직/혈액 분배계수를 구하기 위하여 nonlinear least squares (NLS) 방법이 사용되나 계산 시간이 긴 등의 문제로 파라미터를 각화소마다 구해야 하는 파라메트릭 영상 구성에는 적합하지 않다. 이 연구에서는 이와 같은 NLS 문제점을 극복하여 파라메트릭 영상을 빠르게 구성하기 위하여 제안된 파라미터 추정 알고리즘들을 구현하고, 이 방법들의 통계적 신뢰도와 계산의 효율성을 비교하였다. 대상 및 방법: 이 연구에서 이용한 방법들은 linear least squares (LLS), linear weighted least squares (LWLS), linear generalized least squares (GLS), linear generalized weighted least squares (GWLS), weighted integration (WI), 그리고 model-based clustering method (CAKS)이다. 노이즈 정도에 따른 각 파라메트릭 영상법의 정확성 및 통계적 신뢰성을 알아보기 위하여 Zubal 뇌모형(brain phantom)으로부터 동적 PET 영상을 모사하고 포아송노이즈를 더한 후 각 파라메트릭 영상 구성 방법을 적용하였다. 또한 정상인 16명에 대하여 얻은 실제 자료에 대하여 이 방법들을 적용하고 결과를 비교하였다. 결과: 뇌혈류와 분배계수에 대한 평균 오차는 방법에 따라 크게 다르지 않았으며 모든 방법이 뇌혈류 및 분배계수 추정에 있어 무시할 만한 바이어스를 보였다. 파라메트릭 영상의 정성적 특성 또한 유사하였으나 CAKS 방법의 계산 속도가 월등하여 NLS 방법의 약 1/500, LLS 방법의 약 1/25의 계산시간을 보였다. 결론: 뇌혈류 파라메트릭 영상 구성을 위한 빠른 파라미터 추정 알고리즘들 중에 보다 개선되어 제안된 LWS, GLS, GLWS, CAKS 방법들이 단순하고 빠른 LLS, WI 방법들에 비하여 통계적 신뢰성을 크게 향상시키지는 못하나 CAKS 방법은 계산 시간을 유의하게 단축시키므로 가장 적합한 파라메트릭 영상 구성방법이라 할 수 있을 것이다.

• Journal of the Korean Data and Information Science Society
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• 제21권6호
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• pp.1343-1351
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• 2010

Sample size determination is very important part in clinical trials because it influences the time and the cost of the experimental studies. In this article, we consider the Bayesian methods for sample size determination based on hypothesis testing. Specifically we compare the usual Bayesian method using Bayes factor with the decision theoretic method using Bayesian reference criterion in mean difference problem for the normal case with known variances. We illustrate two procedures numerically as well as graphically.

• 한국콘텐츠학회논문지
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• 제14권12호
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• pp.1037-1046
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• 2014

본 연구는 네트워크 분석을 통해 국내 '변증' 연구의 동향을 살펴보기 위한 것이다. 분석은 년간 논문 수, 저널별 논문 수, 연구 분류별 논문 수 등을 살펴보았으며, 네트워크 분석은 키워드 쌍을 사용하여 수행하였다. OASIS(Oriental Medicine Advanced Searching Integrated System) 시스템에서 검색한 810건의 논문 중에서 368건의 논문을 분석에 사용하였다. 결과적으로, 최근 10년간 변증 관련 논문은 증가하였으며, "Korean journal of oriental physiology & pathology" 저널과 "Journal of korean oriental internal medicine" 저널이 변증관련 가장 많은 논문을 출판하였다. 연구 분류별로 살펴보면, 단면연구가 144편으로 가장 많았고, 환자 사례보고가 71편이었다. 무작위임상시험의 경우에는 단지 3편의 논문만이 있었다. 변증연구에서는 troke, pattern analysis, blood stasis 키워드가 많이 주요 네트워크를 이루었다.

• Clinical and Experimental Reproductive Medicine
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• 제38권1호
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• pp.37-41
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• 2011

Objective: To compare the effectiveness and convenience of a pen device for the self-administration of follitropin ${\beta}$ with a conventional syringe delivering follitropin ${\beta}$ solution in patients undergoing IVF-ET. Methods: GnRH agonist long protocol was used for controlled ovarian stimulation (COS) in all subjects. A total of 100 patients were randomized into the pen device group or the conventional syringe group on the first day of COS. Local tolerance reactions were assessed within 5 minutes, at 1 hour and at 3 hours after each injection. On the day of hCG injection, patients were asked to rate their overall pain and convenience experienced with self-injection on a visual anlaogue scale (VAS). Results: There were no differences in patients' characteristics between the two groups. The duration of COS was significantly shorter in the pen device group than in the conventional syringe group. Patients included in the pen device group needed a significantly smaller amount of follitropin ${\beta}$. However, no differences between the two groups were found in IVF results and pregnancy outcome. The incidence of local pain within 5 minutes, at 1 hour and at 3 hours after the injection was significantly lower in the pen device group. VAS scores indicated that injections using the pen device were significantly less painful and more convenient. Conclusion: The pen device for self-administration of follitropin ${\beta}$ is less painful, safer and more convenient for the patients, and can be more effective because of the shorter duration and smaller dose of follitropin ${\beta}$ when compared with the conventional syringe.

• Pediatric Infection and Vaccine
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• 제8권2호
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• pp.206-212
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• 2001

최근 소아의 인두염 및 인두편도염에서 EM-resistant group A streptococci가 15~40%까지 보고가 되고 있으며, 같은 계통의 macrolide제제들의 대한 내성도 점차 증가하고 있는 양상이 나타나고 있다. 따라서 세균성 인두편도염이 의심되는 환아의 치료에 있어서 경구용 항생제를 선택할 때는 항생제에 대한 내성과 경제성 및 환아의 순응도를 고려하여 항생제를 선택하여야 하겠다.