• Journal of Korean Medical classics
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• v.27 no.3
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• pp.155-166
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• 2014

Objectives : Many keyboarding staff are required for compositional herb data entry from ancient documents. It's the most difficult thing to build DB. So, we have studied to solve this problem. Methods : We have used Windows 7 and Access2013 for automatic extraction compositional herb in the Taipinghuiminhejijufang(太平惠民和劑局方). First of all, we have made synonyms list of herbs and list of herb volumes notation. And than we have analyzied order of arrangements between names of herb and notations of herb volume. Results : We have analyzied a part of prescriptions in the Taipinghuiminhejijufang(太平惠民和劑局方) (519 prescriptions). After 91 seconds, we can complete automatic extraction of compositional herb from 519 prescriptions. Conclusions : If we can analyzie order of arrangements between names of herb and notations of herb volume, we can automatically extract compositional herb of prescription from ancient documents.

• The Journal of Korean Medical History
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• v.28 no.1
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• pp.53-60
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• 2015

Objectives : This is what tries to study irregular pairs between five viscera and five tatstes. And than tries to make convincing explanation. Methods : We analysed "SuWen ZangQiFaShiLun素問 藏氣法時論", "YiXueQiYuan醫學啓源", "TangYeBenCao湯液本草", "BenCaoGangMu 本草綱目" and "FuXingJueZangFuYongYaoFaYao輔行訣臟腑用藥法要". We found difference and similarities between these books. Result & Conclusions : "YiXueQiYuan", "TangYeBenCao", "BenCaoGangMu" inherit pairs between five viscera and five tatstes from "ZangQiFaShiLun". "YiXueQiYuan" had added examples of herbs to "ZangQiFaShiLun". "TangYeBenCao" had added examples of priscriptions to "ZangQiFaShiLun". "BenCaoGangMu" had added examples of herbs to "ZangQiFaShiLun". But new pairs between five viscera and five tatstes had suggested in the "FuXingJueZangFuYongYaoFaYao". We think that the new pairs are more logical than the others.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.2
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• pp.359-370
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• 2004

Before the current western medicine was spreaded out in the world as the main stream, each country had treated diseases with the medicine of their own and the traditional medical books, which are so characteristic, are handed down. Considering the earnest assignment to do in Korean medical of this age and one of the tendencies of medical circles in the world is putting together the current medicine with the traditional medicine, the production and spread of the classification system for the technical books which is contained the characteristic of traditional chinese medicine, the present condition of modern chinese medicine, and the future of it, must be settled without delay. The classification system for oriental medicine section developed in the range of the simple system before the time of flowering, since then the western medicine had grew as the main current in medicine in Korea. But until now the rational and realistic classification system based on the changeable time isn't be established, so setting up one of the classification systems for medicine section, it is classified according to the principle of classification system for medicine section. Hereupon, the result was made after researching the changes of modern classification system for korean and studying on the changes of classification system for oriental medicine section of the Korean decimal classification.

• The Korean Journal of Nuclear Medicine
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• v.37 no.5
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• pp.288-300
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• 2003

Purpose: To obtain regional blood flow and tissue-blood partition coefficient with time-activity curves from ${H_2}^{15}O$ PET, fitting of some parameters in the Kety model is conventionally accomplished by nonlinear least squares (NLS) analysis. However, NLS requires considerable compuation time then is impractical for pixel-by-pixel analysis to generate parametric images of these parameters. In this study, we investigated several fast parameter estimation methods for the parametric image generation and compared their statistical reliability and computational efficiency. Materials and Methods: These methods included linear least squres (LLS), linear weighted least squares (LWLS), linear generalized least squares (GLS), linear generalized weighted least squares (GWLS), weighted Integration (WI), and model-based clustering method (CAKS). ${H_2}^{15}O$ dynamic brain PET with Poisson noise component was simulated using numerical Zubal brain phantom. Error and bias in the estimation of rCBF and partition coefficient, and computation time in various noise environments was estimated and compared. In audition, parametric images from ${H_2}^{15}O$ dynamic brain PET data peformed on 16 healthy volunteers under various physiological conditions was compared to examine the utility of these methods for real human data. Results: These fast algorithms produced parametric images with similar image qualify and statistical reliability. When CAKS and LLS methods were used combinedly, computation time was significantly reduced and less than 30 seconds for $128{\times}128{\times}46$ images on Pentium III processor. Conclusion: Parametric images of rCBF and partition coefficient with good statistical properties can be generated with short computation time which is acceptable in clinical situation.

• Journal of the Korean Data and Information Science Society
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• v.21 no.6
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• pp.1343-1351
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• 2010

Sample size determination is very important part in clinical trials because it influences the time and the cost of the experimental studies. In this article, we consider the Bayesian methods for sample size determination based on hypothesis testing. Specifically we compare the usual Bayesian method using Bayes factor with the decision theoretic method using Bayesian reference criterion in mean difference problem for the normal case with known variances. We illustrate two procedures numerically as well as graphically.

• The Journal of the Korea Contents Association
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• v.14 no.12
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• pp.1037-1046
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• 2014

This study aims to analyze Korea's trend of 'pattern identification(PI)' research using network analysis. We selected 368 papers from OASIS (Oriental Medicine Advanced Searching Integrated System) by review of two Korean medicine experts. Network analysis between keyword of PI studies were performed. As a result, number of PI studies has increased over the last 10 years. 'Korean journal of oriental physiology and pathology' and 'Journal of Korean oriental internal medicine' have published most papers related to PI. As research category, there are 144 papers in the cross-sectional study, and 71 papers in case report study. In the case of randomized clinical trials, there are only 3 papers. In studies for PI, stroke, pattern analysis, and blood stasis were the keywords make up the main network.

• Clinical and Experimental Reproductive Medicine
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• v.38 no.1
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• pp.37-41
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• 2011

Objective: To compare the effectiveness and convenience of a pen device for the self-administration of follitropin ${\beta}$ with a conventional syringe delivering follitropin ${\beta}$ solution in patients undergoing IVF-ET. Methods: GnRH agonist long protocol was used for controlled ovarian stimulation (COS) in all subjects. A total of 100 patients were randomized into the pen device group or the conventional syringe group on the first day of COS. Local tolerance reactions were assessed within 5 minutes, at 1 hour and at 3 hours after each injection. On the day of hCG injection, patients were asked to rate their overall pain and convenience experienced with self-injection on a visual anlaogue scale (VAS). Results: There were no differences in patients' characteristics between the two groups. The duration of COS was significantly shorter in the pen device group than in the conventional syringe group. Patients included in the pen device group needed a significantly smaller amount of follitropin ${\beta}$. However, no differences between the two groups were found in IVF results and pregnancy outcome. The incidence of local pain within 5 minutes, at 1 hour and at 3 hours after the injection was significantly lower in the pen device group. VAS scores indicated that injections using the pen device were significantly less painful and more convenient. Conclusion: The pen device for self-administration of follitropin ${\beta}$ is less painful, safer and more convenient for the patients, and can be more effective because of the shorter duration and smaller dose of follitropin ${\beta}$ when compared with the conventional syringe.

• Pediatric Infection and Vaccine
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• v.8 no.2
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• pp.206-212
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• 2001

Objective : To determine the clinical and bacteriologic efficacy and safety of Cefprozil in acute pharyngitis and pharyngotonsilitis caused by Group A beta hemolytic streptococci in pediatric patients. Methods : Any patient of 3 to 14 age who visited the hospitals enrolled in this study with the signs and symptoms of pharyngitis or pharyngotonsilitis since July, 2000 to March, 2001, was taken throat culture and given Cefprozil(15 mg/kg/day, in two divided doses) for 10 days. 138 patients of whom showed positive culture results were followed up for the signs and symptoms during the treatment to determine clinical efficacy. Any undesirable effect was reported to determine the safety of the drug. Follow up cultures were done at the end of the study and bacteriologic efficacy was determined. Results : 138 of 256 patients who visited the hospitals with the signs and symptoms of pharyngitis or pharyngotonsilitis showed positive growth on throat culture. Mean age of the patients was $6.1{\pm}2.5$ and males and females were equally numbered. 129 of them complained fever on the first visit and 112(86.6%) of them were improved at the end of the study. Cervical lymphadenitis was seen in 58 patients and 44(75.9%) of them improved at the end of the study. Exudative pharyngitis was seen in 96 patients and 81(84.3%) of them improved. The overall clinical effcacy based on this results showed that 110(79.7%) of the patients were cured and 17(12.3%) of them improved. On the cultures and bacteriologic efficacy, 24.6% of them showed documented eradication after treatment and 62.3% of them showed presumptive eradication. Sensitivity test was done by agar dilution method and Cefprozil showed 100% sensitivity. Erythromycin, Clarithromycin and azithromycin showed 87%, 85.6 %, 90.6% sensitivity, respectively. Conclusion : Cefprozil is proved to be effective in controlling group A streptococcal pharyngitis and pharyngotonsilitis in children and showed good sensitivity. Cefprozil can be used as an effective oral cephalosporin in the patients showing penicillin hypersensitivity or patients who other drugs have failed.