• 부모자녀건강학회지
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• 제5권2호
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• pp.177-190
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• 2002

This study were conducted to assess the physical growth and developmental status of infants in orphanage in order to provide an empirical data. The subjects for this study were 104 infants and toddlers who were reared in an orphanage in D Metropolitan city. The instrument used for this study were anthropometric assessment and DDST for normative data of development. Data has been collected from September 1st, 1998 to August 31st, 2000 and were analyzed using SPSS/PC(Version 10.0) with frequency, mean, standard deviation, ANOVA and Chi-square test. The results of this study were as follows; 1. 30.8% of infants in orphanage had abnormal weight, 26.9% had abnormal length, and 22.1% had abnormal head circumference and most of them were distributed below 50 percentile of growth chart. 2. 53.8% of infants in orphanage had normal, 27.9% had qustionable, and 18.3% had abnormal developmental screening test results, especially, 31.5% of infants in orphanage ages 3 to 5 years had abnormal developmental screening test results, according to the Denver Developmental Screening Test(DDST). There was a significant developmental delay noted in the language and fine motor-adaptive sector. 3. It is anticipated that developmental delays would increase in severity by older the mean age of orphanage infants and longer the time being raised in orphanage. It would be concluded that the physical growth and developmental status of orphaned infants were very vulnerable and serious and it is suggested that there needed an effective intervention strategies to promote growth and development of infants in orphanage.

• Toxicological Research
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• 제35권4호
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• pp.343-351
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• 2019

Many in vitro developmental toxicity assays have been proposed over several decades. Since the late 1980s, we have made intermittent attempts to introduce in vitro assays as screening tests for developmental toxicity of inhouse candidate products. Two cell-based assays which were developed two decades apart were intensively studied. One was an assay of inhibitory effects on mouse ascites tumor cell attachment to a concanavalin A-coated plastic sheet surface (MOT assay), which we studied in the early days of assay development. The other was an assay of inhibitory effects on the differentiation of mouse embryonic stem cell to beating heart cells (EST assay), which we assessed more recently. We evaluated the suitability of the assays for screening in-house candidates. The concordance rates with in vivo developmental toxicity were at the 60% level. The EST assay classified chemicals that inhibited cell proliferation as embryo-toxic. Both assays had a significant false positive rate. The assays were generally considered unsuitable for screening the developmental toxicity of our candidate compounds. Recent test systems adopt advanced technologies. Despite such evolution of materials and methods, the concordance rates of the EST and MOT systems were similar. This may suggest that the fundamental predictivity of in vitro developmental toxicity assays has remained basically unchanged for decades. To improve their predictivity, in vitro developmental toxicity assays should be strictly based on elucidated pathogenetic mechanisms of developmental toxicity.

• Child Health Nursing Research
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• 제14권3호
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• pp.261-268
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• 2008

Purpose: This study was conducted to estimate the prevalence of questionable development according to developmental screening testing for children, and to explore biological and environmental risk factors of developmental delays. Method: The study participants were 153 children under two years of age. A questionnaire and Home Observation for measurement of the Environment (HOME) inventory were used to collect data, and Korean Denver II was administered. Results: The overall prevalence of questionable development was 11.1%. Significant differences in biological factors between the normal development group and questionable development group were the rate of prematurity, twins, the educational level of mother and father's and the presence of an illness in the mother (p<.10). Maternal acceptance in HOME was significantly different between the two groups. The factors related to questionable development that were significant in the logistic regression analysis were prematurity (OR=3.56, p=.026), and maternal acceptance in HOME score (OR=.629, p=.028). Conclusion: Early developmental screening tests seem necessary for all children, especially for prematurely born children. Also, child rearing environments were identified as significant factors in the development of all children. These findings suggest that the HOME scores might be useful in identifying children at risk for developmental delays, and that interventions for these children will probably be more effective if their mothers are helped to provide a more appropriate social environment.

• 대한감각통합치료학회지
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• 제5권1호
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• pp.41-49
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• 2007

Objective: To evaluate the effectiveness of the home-based program composed of sensory diet for child with sensory modulation disorder. Method: The subject underwent the home-based program composed of sensory diet for 8 months. Evaluation tools we used are the Developmental Screening Test II(DDSTII) for developmental screening; the Short Sensory Profile(SSP), clinical observation and the clinical history record form for sensory integrative function; the Motor-Free Visual Perception Test(MVPT) and draw a person test for visual perception. Evaluation was executed before and after the program is provided. Results: The subject has showed remarkable improvement in developmental level, sensory integrative function and visual perceptual ability after went through the home-based program. Conclusion: The home-based program composed of sensory diet is effective for children with sensory modulation disorder when it is difficult to apply classical sensory integrative approach.

• 지역사회간호학회지
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• 제13권1호
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• pp.89-97
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• 2002

Purpose: The purpose of this study is to explore the validity of the application of the Denver II developmental screening test to Korean children. This screening test. which was developed and standardized in United States. was designed to screen for developmental delay in Korea. and to compare the levels of development of Korean children with the development of children from the U.S. Method: Quota sampling. NP To facilitate field sampling. the age range used from 0 to 6 years old. was split into 10 different age groups. Sample size was estimated according to residence. 1.054 children were recruited from Seoul's metropolitan. urban and rural areas. NP To fill the quota established. the Recruitment and testing of children was done at public health centers, pediatric outpatient clinics of general hospitals and a child care center. The 25, 50, 75 and 90 percentiles were identified by using logistic regression analysis and were calculated as norms. The items in which the ages of both 50 and 90 percent passing differed more than 20 percent by the calculation was identified for comparison. NP Result: There were significant differences found in 45 items between Korean children and the children from the City of Denver as it relates to age differences. 90% of the sample passed items among 125 items from 4 sectors, e.g., personal- social. fine motor adaptive, language, and gross motor sectors. Korean children were found to be advanced in 9 items, whereas there were significant differences found in 38 items in our comparison of the two countries for age differences when 50% of sample pass items. Korean children were found to be advanced in 16 items. NP Conclusion: The result showed that there was a discrepancy in the developmental norms. It could be explained by the differences in the developmental environment. including child rearing patterns and ethnicity. Therefore, a restandardization of the Denver Screening Test is necessary as it relates to its application on Korean children. This restandardization is necessary in order to avoid both under and over-referrals of children with developmental abnormality. The modification of items in the language sector is especially suggested.

• Clinical and Experimental Pediatrics
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• 제59권12호
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• pp.483-489
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• 2016

Purpose: We investigated the number of test takers of the Korean-Developmental Screening Test (K-DST) in a single children's hospital within a year, according to age, referral rate, and follow-up percentage. Methods: For this study, 4,062 children who visited and received K-DST at Woorisoa Children's Hospital between January and December 2015 were enrolled. Seven test sets were used according to the Korean National Health Screening Program for infants and children in the following age groups: 4 to 6, 9 to 12, 18 to 24, 30 to 36, 42 to 48, 54 to 60, and 66 to 71 months. The results of the K-DST were categorized into 4 groups as follows: further evaluation (<-2 standard deviation [-2SD]), follow-up test (-2SD to -1SD), peer level (-1SD to 1SD), and high level (>1SD). Results: The test participants' population and follow-up population were concentrated before the age of 24 months (2,532, 62.3%). The children most commonly referred for further evaluation were those in the 30- to 41-month age group. A mismatch was found between the results of the K-DST and the additional questions. Most of the infants and children with suspicious developmental delays showed catch-up development in their follow-up tests (43 of 55, 78.2%). Conclusion: The use of K-DST should be encouraged, especially among children aged over 24 months. Multiple-choice question format for the additional questions is recommended to avoid confusion. We suggest a nationwide study to evaluate and revise the K-DST.

• 지역사회간호학회지
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• 제12권1호
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• pp.49-59
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• 2001

Purpose: This study was intended to develop the framework of public health center based 'Child growth and developmental clinic' and analyze the efficiency of services. This was the part of Mother-Child Health Guidance Project by the Public Health Center in Seoul. The purposes of this project were to improve children's health and development with early detection of developmental delay by screening test, and to assist and guide the parent for child care and rearing, so that children can reach their maximum potential. Method: Framework and standards for operation of 'Child growth and development clinic' were developed. We selected screening tool. developed parent education materials, and educated the personnel of public health center. Result: 243 children were enrolled for developmental screening, and we detect the children with developmental delay and referred them for further evaluation. The proportion of developmental delayed children was approximately 2% of the enrolled children. Also, we analyzed the characteristics of enrolled children, and their parental needs and attitude on child rearing. Some problems in operation of developmental clinic were discussed. Conclusion: Though we can found some limitations, we are confident that pubic health center can be charge of important role for improving child development for the majority. This study will be the basis of children's developmental clinic running by public health center.

• 아동학회지
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• 제27권4호
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• pp.39-53
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• 2006

The Korean version of the Child Development Inventory (K-CDI) is a developmental screening test for children functioning in the one-six year range. Based on parent-report, the inventory assesses child developmental functioning in the areas of social, self-help, gross motor, fine motor, expressive language, language comprehension, letter and number skills, general development, and various symptoms and behavior problems. Participants were recruited from childcare centers and private groups and finally 1,143 children and their mothers from 4 locations nationwide participated in this study. Through analysis of item response rate of 270 items in 9 areas, new norm was formed. Reliability determined by internal consistency were relatively high (Cronbach ${\alpha}=.95$). Intercorrelations among sub-scales (range: .49-.96) indicated the construct validity, and the correlation between K-CDI and other screening tests supported the concurrent validity.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제34권2호
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• pp.141-149
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• 2023

Objectives: Most developmental screening tests have been built as parent-performed questionnaires. However, they often do not guide parents on how to answer the questionnaire. This study aimed to develop easily applicable parent guidelines. Methods: We implemented the Delphi procedure with 20 panelists. The development of the initial questionnaire was based on the results of two surveys of parents and experts provided by a policy research report that investigated the item adequacy of the Korean Developmental Screening Test. Round one included 33 items comprising all possible measurements in six categories that were identified as difficult to understand or confusing. Round two merged and modified some items and included 32 items. We defined consensus as a median agreement value of one or less and convergence and stability values of 0.5 or less. The subjective usefulness of the parent guidelines was examined based on their previous test experiences. Results: Consensus was reached after the second round, reflecting the items with the highest level of accuracy in each category. Of the 167 parents who participated in the survey, 113 (67.7%) affirmed the usefulness of the guidelines, while 10 (6.0%) answered that they were not useful. Items that recommended a different scoring strategy in answering the questionnaire from their previous measurements were found to be more useful by the parents. Conclusion: The parent guidelines, composed of five bullet points, drew on the consensus of the experts. Further studies are required to assess whether these guidelines improve the accuracy of screening tests in clinical settings.

• Clinical and Experimental Pediatrics
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• 제48권12호
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• pp.1337-1341
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• 2005

목 적 : 한국형 영유아 발달검사는 발달 선별 검사의 하나로 조대운동, 미세운동, 개인-사회성, 언어, 인지-적응 등의 5가지 영역으로 검사가 이루어지며 본 연구에서는 한국형 영유아 발달검사를 미숙아에게 실시하여 발달지연의 추적 관찰에 있어서 선별 검사로 사용할 수 있는지를 검토하고자 하였다. 방 법 : 2002년 8월부터 2004년 7월까지 고려대학교 의과대학 안산병원에서 태어난 미숙아를 대상으로 하였으며, 한국형 영유아 발달검사를 1번 이상 시행한 환아 74명을 대상으로 하였다. 후에 신경학적 이상이 있는 것으로 판명된 경우(환아군)와 아닌 경우(정상군) 두 그룹으로 나누어 4개월, 7개월, 12개월, 18-24개월에 발달지수를 비교하였으며 80점 미만인 경우 비정상으로 판정하였다. 결 과 : 정상아군과 환아군에서 7개월경에는 미세운동(P<0.05)과 조대운동영역(P<0.01)에서 유의한 차이를 나타내었다. 12개월 및 12개월 이후에는 미세운동, 조대운동, 개인-사회성, 언어, 인지-적응 등 5가지 영역에서 환아군에서 유의한 차이를 나타내었다(P<0.05). 결 론 : 본 연구에서는 미숙아에서 한국형 영유아 발달검사가 후에 영유아의 신경학적 이상을 예측하는데 선별검사로 의미가 있는지를 알아본 결과 지속적인 관찰과 반복검사로 유용하게 사용될 수 있겠다.