• 한방재활의학과학회지
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• 제23권4호
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• pp.251-259
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• 2013

The purpose of this study is to observe the effect of Korean medicine treatment in combination with intra-articular bee venom injection and needle-embedding therapy on recurrent patellar dislocation in patient. The Patient, diagnosed as recurrent patellar dislocation, was treated by Korean medicine treatment in combination with intra-articular bee venom injection and needle-embedding therapy. Visual analogue scale (VAS), knee flexion range of motion (ROM), Korean Western Ontario and Mcmaster Universities arthritis index (K-WOMAC) were used to measure changes during treatment. After treatment, VAS, knee flexion ROM, K-WOMAC were improved significantly. The Korean medicine treatment in combination with intra-articular bee venom injection and needle-embedding therapy was proved to be helpful to improve the symptoms of the recurrent patellar dislocation.

• 혜화의학회지
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• 제22권2호
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• pp.111-117
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• 2014

Objective : This is a case series reporting degree of response to bee venom ointment as a symptom-control therapy for chemotherapy-induced peripheral neuropathy (CIPN). Methods : Four consecutive patients with CIPN were referred to the East-West Cancer Center from October 7th, 2013, to November 9th, 2013. Patients with CIPN were treated with bee venom ointment 1-2 times per day for 7-25 days. Visual Analog Score (VAS) pain scale was compared before and after treatment. All patients were closely examined for any allergenic responses following each treatment session. Results : Using each patient as their own comparator, marked improvements of VAS were observed in 4 patients. Most important, there were no related adverse side effects found. Conclusion : Bee venom Ointment may be considered as an complementary therapy for managing CIPN symptoms.

• Journal of Acupuncture Research
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• 제18권3호
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• pp.227-238
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• 2001

Objective : There was no report on the treatment of Fascioscapulohumeral (FSH) Muscular Dystrophy by Oriental medicine. But the treatment conducted on the patient admitted to the Sangji Oriental Medicine Hospital from January 9, 2001 to February 23, 2001, a significant treatment result was yielded and would like to suggest treatment plan for the future treatments. Methods : Under the assumption that Korean Bee-Venom Therapy may be affective for treating FSH Muscular Dystrophy, the following points were administered : SI10(노유), SI11(天宗), BL23(腎兪), BL26(關元兪), ST36(足三里), LI4(合谷), Liv3(太衝), SI9(肩貞). CFC(Carthami Flos;紅花 and Cervi Pantotrichum Cornu;鹿茸) herbal extract was treated on the other acupuncture points. Sa-Am(Four needle technique) Acupuncture (tonifying SI5 and ST42, sedating GB41 and ST43) was done every day. For herbal medicine, TaeEumIn ChoWiSeungChung-Tang was given based on the constitutional diagnosis. Results : After 7 weeks of treatment, a remarkable improvement was made for facial muscular movement and muscular strength of the scapular and another regions. Conclusions : 1. Significant improvement in the muscular strength for the case of FSH Muscular Dystrophy was obtained with through Korean Bee-Venom Therapy, Four needle technique, and herbal medication. 2. For progressive muscular dystrophy, it is necessary to practice muscular strength recovery exercise in conjunction with Korean Bee-Venom Therapy. 3. Although this case yielded favorable result, further observation and study must be made to concretely prove the effectiveness of Korean Bee-Venom Therapy for treating muscular dystrophies.

• 대한한의학회지
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• 제25권2호
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• pp.207-219
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• 2004

Objectives : We investigated to find the relationship between single-nucleotide polymorphism (SNP) of IL4R, IL-10 and bee venom therapy efficacy in patients with RA treated with bee venom for 8 weeks. Methods : Korean RA patients (n=114) and healthy subjects (n=109) were included in this prospective study. Korean bee venom was dissolved in saline (diluted 1:3000) and administrated into acupuncture points. Bee venom therapy was applied twice a week and continued for 8 weeks. The clinical response was evaluated using various assessments before and after treatment. Disease severity was measured by determining the number of tender joints and swollen joints. Laboratory studies included ESR, CRP, and rheumatoid factor. Genotyping for IL-4R and IL-10 polymorphism was done by pyrosequencing analysis. Results : 1. In IL4R genotypes, there was significant difference between RA ptitients tind controls group. 2. In IL4R genotypes, there was significant difference among Good, Mild and Bad responders to in RA patients, but in the frequency of alleles and carriers, there were no significant difference. 3. There was no significant difference between RA patients and controls group in IL-10 gene genotypes. 4. In IL-10 genotypes, there was no significant difference among Good, Mild and Bad responders to in RA patients. 5. There was no significant difference in the improvement of ESR, CRP and KHAQ scores after bee venom therapy in RA patients among the IL4R or IL-10 genotypes. Conclusions : In IL-4R genotypes, there was significant difference between RA patients and control group, and among Good, Mild and Bad responders in RA patients. However, in IL-10 genotypes, there was no significant difference between RA patients and controls group and among Good, Mild and Bad responders in RA patients.

• Journal of Acupuncture Research
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• 제20권3호
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• pp.217-228
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• 2003

Objective : Spinal meningeal cysts can be the cause of the low back pain and sciatica. We tried to manage the low back pain and sciatica caused by other disease besides intervertebral disc herniation. Methods : We treated the patient who diagnosed as spinal meningeal cyst and hospitalized. And we investigate the progress of physical condition, VAS, modified VAS, PRS by treatment and MRI before and after treatment. Results : There was remarkable improvement in condition of the patient who has spinal meningeal cyst after bee venom therapy. We found the size of cyst decreased in MRI and also progress in VAS modified VAS PRS physical view improved. Conclusions : We think that the result of this case can be a pilot study that proves the effect of bee venom therapy the low back pain and sciatica caused by variable disease.

• 한국임상수의학회지
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• 제16권1호
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• pp.145-149
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• 1999

This study was designed to examine therapeutic effect of natural honeybee (Apis mellifera) venom in pigs with arthritis. Pigs were assigned to treated and nontreated control groups. In treated group, 51 pigs were given natural honeybee venom once a day for 5 consecutive days. Acupoints of Sam-li, Jok-su and Pal-ja were stung by the natural honey bees. In control group, 46 pigs were intramuscularly injected with a standard dosage of penicillin G (400,000 IU/kg of body weight) once a day for 5 consecutive days. On day 5 following bee venom therapy, 73.9% of control pigs and 86.2% of pigs in treated group recovered from arthritis. Bee acupuncture therapy did not show any side effects such as allergy, intoxication, hemorrhage, or infection. It might be concluded that honeybee venom therapy was effective in controlling of pig with arthritis.

• 한국임상수의학회지
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• 제17권1호
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• pp.57-61
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• 2000

This study was designed to examine therapeutic effect of bee(Apis mellifera L.) venom in calves with bacterial diarrhea. Calves with bacterial diarrhea were administered with bee venom and therapeutic drug, respectively. In the bee venom-treated group, 69 calves were acupunctured once a day for 3 conseutive days. Two local acupoints of Jiao-chao(GV-1, at the indentation between the base of tail and the anus) and Bai-hui(GV -20, in the dorsal midline of the lumbo-sacral space) were stung by the bee. In the therapeutic drug-treated group, 55 claves were intramuscularly injected with a standard dosage of antibiotic (ciprofloxacin, 2.5 mg/kg of body weight) and antidiarrheal drug (berberine cholride, 10mg/head) once a day for 3 consecutive days. At post-treatment, 81.2% of the bee venom-treated calves and 76.4% of the therapeutic drugtreated calves were recovered from bacterial diarrhea. Bee acupuncture therapy showed in calves without side effects such as allergy hemorrhage, or infection. It might be concluded that apitherapy was affective in controlling of calves with bacterial diarrhea.

• Journal of Acupuncture Research
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• 제27권2호
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• pp.155-160
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• 2010

Objectives : The purpose of this study is to investigate the efficacy of Bee venom Pharmarcopuncture on facial palsy in Herpes Zoster otiucus. Methods : We used the acupuncture and Bee venom Pharmarcopuncture complex therapies on facial palsy in Herpes Zoster otiucus occurred in pregnancy. The improvement of the symptom and facial movement was evaluated by VAS and Yanagihara scale. Results & Conclusions : After treatment, both VAS and Yanagihara's scale were significantly improved. In this case, we found that the acupuncture and Bee venom Pharmarcopuncture complex therapy is effective for facial palsy in Herpes Zoster otiucus.

• 척추신경추나의학회지
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• 제7권2호
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• pp.75-81
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• 2012

장요인대 염좌 환자 2명에게 전열침 치료를 시행하여 통증 강도가 증가하였지만 봉독약침 치료를 시행한 후 통증 강도와 요추 가동범위 및 이학적 검진상에서 호전되었음을 보고한다. 이와 같이 봉독약침에 의해 호전 될 수 있는, 염증성 병변을 내재하였거나 진행 될 가능성이 있는 환자에 대한 사전의 감별 진단에 대한 연구 및 전열침 치료의 효과 및 부작용에 대한 체계적인 연구가 추후에 필요할 것으로 사료된다.

• 대한약침학회지
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• 제3권2호
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• pp.233-244
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• 2000

After observing a patient diagnosed with Progressive Muscular Dystropies from the August, 31, 2000 to the January, 2001, the following results are obtained. Method and Result: Under our assumption that the Korean Bee Venom Therapy is a good method to treat Progress Muscular Dystropies. Korean Bee Venom Therapy was applied on the following acupuncture points: BL23(Shinsu:腎兪), BL26(Guanyuanshu:關元兪), ST36(Chok-Samni:足三里), LI4(Hapkok:合谷), LV3(Taechung:太), SP10(Hyolhae:血海), SI9(Sojang-Kyonjong:貞). In addition CFC(Carthami Flos;紅花: and Cervi Pantotrichum Cornu;) Herbal-Acupuncture is also treated on the other acupuncture points. For herbal medication was given to the patient based on the Sasang Constitution, Taeyangin Ogapijangchuk-tang. Following these treatments in this case of Progressive Muscular Dystropies, the skeletal muscle functions made remarkable improvement. Conclusion: Based on the clinical results, traditional Korean Medical treatment is believed to be effective for treating Progressive Muscular Dystropies, and further studies should be conducted to provide more valuable information.