• Journal of Acupuncture Research
• /
• v.19 no.6
• /
• pp.256-263
• /
• 2002

Objective : This study is to report the radiological change after bee venom therapy about the patient of sequestrated disc. Methods : there was a report that the bee venom therapy was effective treatment on the patient of extruded or sequestrated disc. So we treated the patient who was diagnosed as sequestrated disc and hospitalized, and investigated the change of DITI, simple X-rays and MRI before and after treatment. Results : There was remarkable improvement in condition of the patient who had extruded or sequestrated disc after treated by bee venom therapy. It showed that the region of sequestrated L4-5 dise remarkably decreased in MRI, degree of scoliosis decreased from 17 degree to 15 degree in simple X-ray and the difference of right and left became equal in DITI through the follow-up survey. Conclusions : There was reports that bee venom therapy had antinflammatory and antalgic effect and was effective in treating patient of sequestrated disc and in curing pain, functional disorder, and clinical symptom of HIVD patients by means of grade index of lumbago. We think that the result of this study will be supporting data (that will be able to) proves more objectively the change following the improvement of condition with radiological check.

• The Journal of Churna Manual Medicine for Spine and Nerves
• /
• v.6 no.2
• /
• pp.61-70
• /
• 2011

Objectives : The purpose of this study was to investigate the effect of Bee-venom acupuncture on low back pain by traffic accidents. Methods : We included 34 patients with low back pain caused by TA for this study. The experimental group was treated by usual therapy plus Bee-venom acupuncture therapy, the control group was treated by usual therapy such as acupunture therapy and herbal medicine therapy. Oswestry Disability Index(ODI) and Visual Analog Scale(VAS) were evaluated at 4 week from baseline for the treatment effect in the both group. Results : After the subjects being treated by Bee-venom or general acupuncture therapy. It was detected that the scores of ODI and VAS in both groups decreased at the 4 week from baseline. There was significant difference between both groups in the VAS. However, there was no significant difference between both groups in the ODI. Conclusions : The results suggested that bee-venom acupuncture was effective on low back pain by traffic accidents.

• Journal of Acupuncture Research
• /
• v.20 no.3
• /
• pp.154-165
• /
• 2003

Objective : to research the trend of the study related to Bee venom and o establish the hereafter direction for the study on Bee Venom therapy. Methods : We reviewed the domestic papers published last ten years(1992-2001). Results: 1.We have searched 53 papers in 7 journals and the pattern of study was as follow: the experimental studies were 33, the clinical studies were 10 and the reviewed studies were 10. 2. The experimental studies were 2 papers of analysis of Bee Venom, 3 papers of safety assessment, 1 paper on production of antibody against Bee Venom and 26 paper of safety assessment. 3. Bee Venom used in studies was made in Korea, China and U.S.A.. There were differences of component and effect according to the place of production. 4. There were the experimental studies of LD50 in mouse, acute toxicity, local irritation test, antigenicity and pyrogen test of Bee Venom. Conclusions : We need more studies of unification of term about Bee Venom, difference according to the place of production, clinical safety and effects.

• Korean Journal of Acupuncture
• /
• v.25 no.2
• /
• pp.125-141
• /
• 2008

Objective : The aim of this study is to investigate the curative effect of Bee Venom Acupuncture Therapy for pain and limited R.O.M (range of motion) of shoulder in stroke patients. Methods : The subjects of this study were 6 patients with shoulder pain in stroke sequelae. Routine Oriental Medical programs (Acupunture, moxibustion, herbal medicine and physical therapy) were maintained for each subject throughout this study. Single subject ABABAB design was adopted. Each period was 4 days as a rule. Only during the treatment period, Bee Venom Acupuncture Therapy was provided as intervention at the acupoints of LI15(Gyeonu),　TE14(Gyeollyo), GB21(Gyeonjeong), LI14(Bino). The change of pain was measured with a Visual Analogue Scale(VAS). The pain threshold was measured using pressure algometer at the same acupoints where Bee Venom Acupuncture Therapy was provided. And the R.O.M of shoulder joint (flexion, extension, abduction, adduction, external rotation, internal rotation) was measured as well. Analysis was performed by Bayesian analysis using WinBUGS for the comparison of treatment(Bee Venom Acupuncture Therapy) and non-treatment. Results : The median overall improvement for difference in VAS was -2.219(-3.213, -1.175), for difference in external rotation of shoulder R.O.M was 9.992(-2.298, 18.49), for difference in tenderness score of LI14(Bino) by pressure algometer was 5.05(0.6283, 7.762). 95% credibility intervals being shown in brackets. However, the median overall improvement for difference in the other measurements was not significant. Conclusion : This study suggests that Bee Venom Therapy may be applicable to decrease pain and improve R.O.M of shoulder in hemiplegia patients with stroke. Further elaborated single subject designs need to be accumulated to confirm the effects of Bee Venom Acupunture Therapy on shoulder pain in patients with stroke sequelae.

• Journal of Pharmacopuncture
• /
• v.5 no.2
• /
• pp.109-115
• /
• 2002

Objective : This study was performed to evaluate the treatment of Acupuncture therapy including Herbal Acupuncture theraphy and Korean Bee Venom Theraphy in Klippel-Trenaunay-Weber Syndrome. Methods : We treated 1 case of Klippel-Trenaunay-Weber Syndrome patient with mainly Korean Bee Venom Theraphy, and herbal Acupuncture, acupuncture theraphy from 27th August, 2001 to February, 2003. Results : After 3 weeks of Korean Bee Venom Theraphy, and herbal Acupuncture, acupuncture theraphy, a remarkable improvement was made for Klippel-Trenaunay-Weber Syndrome. Conclusions : Korean Bee Venom Theraphy and other acupuncture therapies were effective in reducing the symptoms. We think that it need the further study and clinical trial for Klippel-Trenaunay-Weber Syndrome.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.22 no.3
• /
• pp.703-707
• /
• 2008

To examine the efficacy of electrical acupuncture combined bee venom in controlling low back with leg pain induced Herniated Intervertebral Disc (HIVD). 13 patients (men 8, women 5; age $41.30\;{\pm}\;17.27$) diagnosed as HIVD by CT or MRI had low back and leg pain as a chief complaint and diseases such as spinal tumor, infection and fracture were excluded. They were treated by electrical acupuncture (8 Hz) combined bee venom therapy three times a week in Wonkwang University Hospital, and pain intensity with VAS and functioning with Roland-Morris Disability Qestionnaire(RDQ) were measured at the baseline(B), and 4 weeks after treatment. The data were analyzed with Wilcoxon signed ranks test(SPSS12.0) and the level set for statistical significance was P<0.05. The pain was significantly reduced by two combined treatments (=0.002;$B7.69{\pm}2.06$,4Wks$4.70{\pm}2.72$). The function was also significantly improved by both treatments(=0.001;$B12.15{\pm}6.85$,4Wks$6.85{\pm}5.15$). The results suggest that a combination of acupuncture and bee venom therapy may be beneficial for low back pain from HIVD. In future, randomized clinical trials including follow-up are needed to examine the effects of these therapies.

• Journal of Korean Medicine Rehabilitation
• /
• v.18 no.3
• /
• pp.201-210
• /
• 2008

Objectives : This report was performed to evaluate the treatment of acupuncture therapy, Bee venom acupuncture therapy and herbal medication in Baastrup's disease. Methods : We treated 1 case of Baastrup's disease with acupuncture therapy, Bee venom acupuncture therapy one times a week and took herbal medicine after a meal two times daily. The patients' symptoms were assessed 3 month, 6 month, 9 month by Visual analogue scale(VAS), Oswestry disability index(ODI). Results : Visual Analog Scale(VAS), Oswestry Disability Index(ODI) was significantly improved after treatment for 9 months. Conclusions : This study suggested that acupuncture therapy, Bee venom acupuncture therapy and herbal medicine can be effective for decreasing pain and improving functional recovery. We think that it need the further study and clinical trial for Baastrup's disease.

• Korean Journal of Acupuncture
• /
• v.37 no.2
• /
• pp.76-87
• /
• 2020

Objectives : Bee venom has been widely practiced in many countries around the world. The number of clinical trials and biochemical researches on bee venom has been constantly increasing. The objective of this study is to analyze the trend of research on bee venom using bibliometric approach, a quantitative analytical method. Methods : We searched articles about bee venom which were published from 2000 to 2019 from Web of Science Database. Original and review articles published in English were included and data were extracted in terms of publication year, country, journal, keywords, organizations, and authors. Trends in bee venom research were visualized using VOSviewer program. Results : 1,547 English articles about bee venom were identified and analyzed. South Korea is a main hub in the field of bee venom research. Research organizations in South Korea showed high link strength with domestic organizations as well as with international organizations. A keyword analysis showed the following three major types of studies: studies on components of bee venom, studies on allergy and immune response, and clinical research of bee venom therapy. Conclusions : This study provides a macroscopic overview of the research on bee venom. This bibliometric analysis has identified influential authors and organizations in the field on bee venom research and provides a useful guideline to researchers who are in search of contributory research topics.

• Journal of Pharmacopuncture
• /
• v.8 no.2
• /
• pp.17-22
• /
• 2005

Objective : This study was performed to evaluate the treatment of acupuncture therapy including. Bee Venom and Hominis Placenta herbal acupuncture on the patient with Transverse myelitis. Methods : We treated the patient with Transverse myelitis by Bee Venom herbal acupuncture at beginning, since then we treated him adding to Hominis Placenta herbal acupuncture. Conclusions: The patient was effectively reduced symptoms with Bee Venom herbal acupuncture, since then he get more effective improvement of symptoms by adding Hominis Placenta herbal acupuncture. Therefore we are able to expect Bee Venom and Hominis Placenta herbal acupuncture will be more effective than simply acupuncture on the patient with Transverse myelitis.

• Journal of Acupuncture Research
• /
• v.27 no.3
• /
• pp.159-166
• /
• 2010

Objectives : This study was to observe the effect of Hapgok needling and Bee Venom Acupuncture on a patient with neuralgia caused by Carpal Tunnel Syndrome. Methods : The patient were treated by Hapgok needling and Bee Venom Acupuncture at acupuncture points following diagnosed as Carpal Tunnel Syndrome. Improvement of the symptoms was evaluated by VAS. Results : Carpal Tunnel Syndrome related symptoms of the patient were remarkably improved by Hapgok needling and Bee Venom Acupuncture therapy. Conclusions : These results suggested that Hapgok needling and Bee Venom Acupuncture should be one of the useful treatment methods for relieving the symptoms of Carpal Tunnel Syndrome.