• 제목/요약/키워드: KoreaMed

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국내 의학 데이테베이스의 활용 (PRACTICAL USE OF KOREAN MEDICAL DATABASE)

  • 이효설;김종수;이제호
    • 대한소아치과학회지
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    • 제39권3호
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    • pp.325-331
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    • 2012
  • 국내 의학 데이터베이스는 주관기관에 따라 다양하다. 국내 주요 의학 데이터베이스로는 대한의학회 산하 대한의학학술지 편집인협의회(KAMJE)의 KoreaMed, KoMCI, Synapse, 국가 주도의 의학연구정보센터(MedRIC)의 KMbase, 한국교육학술정보원(KERIS)의 RISS, 한국과학기술정보연구원(KISTI)의 NDSL, 한국연구재단(NRF)의 KCI가 있다. 민간 유료데이터베이스로는 한국학술정보의 KISS, 누리미디어의 DBpia가 있으며, 포털사이트인 Google과 Naver도 방대한 양의 정보를 제공하고 있다.

한국인에서 대장-직장암의 해부학적 부위별 발생률 조사 (Nationwide incidence estimation of colorectal cancer by subsite of origin in Korea)

  • 박병주;이무송;안윤옥;허대석;김동현;김헌;유하성;박태수
    • Journal of Preventive Medicine and Public Health
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    • 제29권3호
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    • pp.555-563
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    • 1996
  • Nationwide incidence survey was conducted to estimate the annual incidence rates of colorectal cancer among Koreans between Jan 1, 1988 and Dec 31, 1989. The population of the incidence survey was the beneficiaries of Korea Medical Insurance Corporation (KMIC), which were about 4,500,000 persons. The medical records of patients with diagnosis of either ICD-9 153(colon cancer), 154(rectal caner), 197(secondary malignant neoplasm of digestive and respiratory system), or 211(benign neoplasm of digestive system) were abstracted for the period with the standard format. The diagnosis was confirmed by one oncologist through the review of these abstracts. The numerator of the rate was finally defined as the incident colorectal cancer cases diagnosed between July 1, 1988 and June 30, 1989. The crude annual incidence of colorectal cancer for men was 13.1 per 100,000 and 10.6 for women, which was still low when compared with those of Japan and China during the same period. Age-adjusted sex ratio was 1.2 for right-sided colon cancer and 1.9 for left-sided colon cancer. The excess of right colon cancer among postmenopausal women was remarkable, so further analytical approach would be needed to investigate which factors are related with this phenomenon.

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Development of a new Cox-2 inhibitor as an anticancer agent

  • Park, Jeong-Ran;Hyoung, Kang-Jin;Young, Noh-Ji;Chul, Ryu-Hyung;Park, Sang-Wook;Hwan, Cho-Il;H, Hwang-Daniel;Kim, In-Kyung;Jeog, Kuh-Hyo
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.227.1-227.1
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    • 2002
  • Cyclooxygenase (Cox-2) is involved in tumorigenesis. hence. considered to be a molecular target for chemoprevention and chemomodulation. Selective Cox-2 inhibitors including Celecoxib and Nimesulide have been studied for their anticancer activity when given alone and in combination with radiation or cytotoxic agents. In this study, we synthesized more than 140 analogues of Celecoxib and Nimesulide. and evaluated their inhibitory effects on Cox-l and Cox-2 activity as well as cytotoxicity in order to find promising anticancer agents having selective Cox-2 inhibitory effect. (omitted)

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한약재 품질 표시 제도의 도입을 위한 조사 (Investigation for the Induction of Quality Inscription System with Herbal Medicine)

  • 이미영;김호경;전원경;정계진;주영승;주영송;고병섭
    • 한국한의학연구원논문집
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    • 제6권1호
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    • pp.59-68
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    • 2000
  • The purpose of this study is to encourage the circulation of good quality of oriental medicine and to improve national welfare. Investigation for the induction of quality inscription system was conducted by mail and interview. The data were analyzed by SAS. The major results were as follows: The portion of subjects agree to necessity of quality inscription was 78.5%. In the question of side effect against quality inscription, the rate of negative was 67.7%. The responses answered that the necessity of quality inscription was not economical profit but authority of knowledge and improvement on health(37.8%), established market for herbal medicine(34.7%) and effect of clinical care(23.9%), respectively These results might be useful information for establishing of quality inscription system for herbal medicine.

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한국산 "재첩"이 "이전고환극구흡충" 의 제 2 패류중간숙주가 될 수 있는가 (Corbicula fluminea (Bivalvia: Corbiculidae): a possible second molluscan intermediate host of Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea)

  • Chung, Pyung-Rim;Soh, Chin-Thack;Younghun Jung;Hwang, Myung-Gi
    • 한국어업기술학회:학술대회논문집
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    • 한국어업기술학회 2000년도 춘계수산관련학회 공동학술대회발표요지집
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    • pp.502-502
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    • 2000
  • Corbicula fluminea Muller 1884 is the commonest freshwater bivalve in Asian countri including Korea. This clam is easily found in the freshwater systems, and edible as a food source in Korea. This study was aimed to confirm natural infection of C. fluminea collected from various localities with Echinostoma cinetorchis, an important hum intestinal fluke in Korea. (omitted)

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파킨슨성 완서증의 손가락 마주치기 속도와 크기에 대한 약물과 뇌심부자극의 효과 (Effects of Medication and Deep Brain Stimulation on the Finger-tapping Speed and Amplitude of Parkinsonian Bradykinesia)

  • 김지원;권유리;박상훈;엄광문;고성범;장지완;이혜미
    • 대한의용생체공학회:의공학회지
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    • 제33권1호
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    • pp.47-52
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    • 2012
  • The purpose of this study is to investigate whether medication and deep brain stimulation (DBS) have differential effects on the speed and amplitude of bradykinesia in patients with Parkinson's disease (PD). Five PD patients with implanted DBS electrodes (age: $60.6{\pm}7.4yrs$, H&Y stage: $3.1{\pm}0.2$) participated in this study. FT (finger tapping) movement was measured using a gyrosensor system in four treatment conditions: Med (Medication)-off/DBS-off, Med-off/DBS-on, Med-on/DBS-off and Med-on/DBS-on. Quantitative measures representing average speed and amplitude of FT movement included root-mean-squared (RMS) angular velocity and RMS angle. One-way repeated measures ANOVA showed that RMS angular velocity of Med-on/DBS-on was significantly greater than those of Med-off/DBS-off and Med-off/DBS-on (p < 0.01) whereas RMS angle was not different among conditions (p = 0.06). Two way repeated measures ANOVA showed that only medication improved RMS angular velocity (p < 0.01), whereas both medication and DBS had no significant effect on RMS angle (p > 0.02). Effect size of RMS angular velocity was greater than that of RMS angle in both medication and DBS. This suggests that medication and DBS have differential effects on FT bradykinesia and velocity and amplitude impairments may be associated with different functional aspects in PD.

INVOLVEMENT OF CYP2C9 ON CHLORPROPAMIDE 2-HYDROXYLATION IN HUMAN: IN VITRO AND IN VIVO EVIDENCE.

  • Shon, Ji-Hong;Yoon, Young-Ran;Kim, Min-Jung;Cha, In-June;Shin, Jae-Gook
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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    • pp.198-198
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    • 2001
  • No report has been addressed to the CYP isoforms catalyzing chlorpropamide, a structural analogue of tolbutamide. To evaluate enzyme(s) mediating formation of 2-hydroxycWorpropamide, a major metabolite and identified by LC/Mass and NMR, incubation studies using human liver microsomes and cDNA expressed CYP were performed on the presence or absence of selective inhibitors of each CYP isoform. (omitted)

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