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A Review of Herbal Medicinal Products Associated with Toxic Events in Korea (최근 독성 문제가 제기된 한약재에 대한 고찰)

  • Jang, In-Soo;Yang, Chang-Sop;Han, Chang-Ho
    • The Journal of Korean Medicine
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    • v.28 no.1 s.69
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    • pp.1-10
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    • 2007
  • Background : There has been renewed interest in complementary alternative medicine around the world far a decade. On the other hand, the issue of safety of herbal medicine in Korea has been continuously questioned. Issues raised have included not only chemical residue or heavy metals caused by pollution, but also the toxicity of herbal medicine itself. Objectives : The purpose of this study was to review some herbal medicines subject to controversy of toxicity and figure out what kind of problems they evidence. Methods : In this review, PubMed was used to search medical journals. Keywords such as 'herb, or herbal medicine', 'safety, or adverse events, or adverse effect, or toxicity, or liver injury' were applied. Journals were selected by four inclusion criteria, as objectives should be human, researchers should be medical doctors, literature written in the English language, and types of journals should be meta-analysis or practice guideline or reviews. Finally, 9 cases from 60 journals were included in this review. Results : We reviewed 13 herbal medicines for controversy of toxicity such as ephedra(Mahuang), Arisolochia fangchi, Aristolochia manshuriensis, licorice, skullcap , germander, Syo-saiko-to(Xiao-chai-hu-tang), Chelidonium majus, mistletoe, Dictamnus dasycarpus and madder. Conclusions : It suggested that 'who it is prescribed for' is one of the most important factors to identify the causes of toxicity in herbal medicine and dietary supplements, under specific conditions in Korea.

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Number of implants for mandibular implant overdentures: a systematic review

  • Lee, Jeong-Yol;Kim, Ha-Young;Shin, Sang-Wan;Bryant, S. Ross
    • The Journal of Advanced Prosthodontics
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    • v.4 no.4
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    • pp.204-209
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    • 2012
  • PURPOSE. The aim of this systematic review is to address treatment outcomes of Mandibular implant overdentures relative to implant survival rate, maintenance and complications, and patient satisfaction. MATERIALS AND METHODS. A systematic literature search was conducted by a PubMed search strategy and hand-searching of relevant journals from included studies. Randomized Clinical Trials (RCT) and comparative clinical trial studies on mandibular implant overdentures until August, 2010 were selected. Eleven studies from 1098 studies were finally selected and data were analyzed relative to number of implants. RESULTS. Six studies presented the data of the implant survival rate which ranged from 95% to 100% for 2 and 4 implant group and from 81.8% to 96.1% for 1 and 2 implant group. One study, which statistically compared implant survival rate showed no significant differences relative to the number of implants. The most common type of prosthetic maintenance and complications were replacement or reattaching of loose clips for 2 and 4 implant group, and denture repair due to the fracture around an implant for 1 and 2 implant groups. Most studies showed no significant differences in the rate of prosthetic maintenance and complication, and patient satisfaction regardless the number of implants. CONCLUSION. The implant survival rate of mandibular overdentures is high regardless of the number of implants. Denture maintenance is likely not inflenced substantially by the number of implants and patient satisfaction is typically high again regardless os the number of implants.

Attachment systems for mandibular implant overdentures: a systematic review

  • Kim, Ha-Young;Lee, Jeong-Yol;Shin, Sang-Wan;Bryant, S. Ross
    • The Journal of Advanced Prosthodontics
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    • v.4 no.4
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    • pp.197-203
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    • 2012
  • PURPOSE. The aim of this systematic review was to address treatment outcome according to attachment systems for mandibular implant overdentures in terms of implant survival rate, prosthetic maintenance and complications, and patient satisfaction. MATERIALS AND METHODS. A systematic literature search was conducted using PubMed and hand searching of relevant journals considering inclusion and exclusion criteria. Clinical trial studies on mandibular implant overdentures until August, 2010 were selected if more than one type of overdenture attachment was reported. Twenty four studies from 1098 studies were finally included and the data on implant survival rate, prosthetic maintenance and complications, patient satisfaction were analyzed relative to attachment systems. RESULTS. Four studies presented implant survival rates (95.8 - 97.5% for bar, 96.2 - 100% for ball, 91.7% for magnet) according to attachment system. Ten other studies presented an implant survival rate ranging from 93.3% to 100% without respect to the attachment groups. Common prosthetic maintenance and complications were replacement of an assay for magnet attachments, and activation of a matrix or clip for ball or bar attachments. Prosthetic maintenance and complications most commonly occurred in the magnet groups. Conflicting findings were found on the rate of prosthetic maintenance and complications comparing ball and bar attachments. Most studies showed no significant differences in patient satisfaction depending upon attachment systems. CONCLUSION. The implant survival rate of mandibular overdentures seemed to be high regardless attachment systems. The prosthetic maintenance and complications may be influenced by attachment systems. However patient satisfaction may be independent of the attachment system.

Literature Review of Psychosocial Problems, Measurement Tools and Intervention Effects in Patients with Cancer (암환자의 심리사회적 기능, 측정 도구 및 중재 효과에 관한 고찰)

  • Choi, Eun-Ok
    • Journal of Korean Biological Nursing Science
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    • v.7 no.2
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    • pp.31-48
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    • 2005
  • Purpose: Studies focus on cancer control, prevention, or assessment of psychosocial problems and intervention methods. However, few studies exist concerning psychosocial problems, measuring tools for those problems, and interventions for cancer patients in Korea. One of the purposes of this study was to review studies in this area, to examine various psychosocial problems experienced by cancer patients. This is a crucial area to investigate, since psychosocial problems in turn negatively influence the patients' immune function, which speeds the progress of the disease. Another goal was to identify instruments used to measure psychosocial functioning and problems in cancer patients, to analyze their validity and reliability, with the aim to discover the best instruments. A final goal was to explore and compare the effects of psychosocial interventions, to determine the most effective practices. Method: Journal articles published since 1995 were searched from PubMed Data base, Google search engine, and published cancer-related studies, using search keywords "psychosocial function and intervention for the cancer patients"; whole articles of selected references were reviewed and analyzed. Result: Most common psychosocial problems were depression, fatigue, nausea, pain, distress, resulting in a low quality of life. The seven scales found in the literature to assess the psychosocial functioning were Center for Epidemiological Studies-Depression, State-Trait Anxiety Inventory, Symptom Checklist 90-R, Profile of Mood States, Psychosocial Adjustment to Illness Scale, Brief Symptom Inventory, and SF-36 HRQOL(Health Related Quality of Life). Social support interventions for cancer patients were effective in improving quality of life scores. Conclusion: It is necessary to apply support intervention strategies to help cancer patients in Korea. These strategies can help to reduce the effects of psychosocial symptoms, which in turn affect the development and control of cancer. Strategies developed in Western countries may need to be modified for use within Korea. Further studies are warranted to review the support intervention strategies that were being used to for cancer patients

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Association between dental X-ray exposure and the thyroid cancer risk: A meta-analysis of case-control studies

  • Hwang, Su-Yeon;Kim, Hae-Young;Song, Sun-Mi;Choi, Eun-Sil
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.3
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    • pp.269-279
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    • 2020
  • Objectives: Previous studies have reported inconsistent findings in the association between dental diagnostic X-ray exposure and thyroid cancer. This study was a meta-analysis of case-control studies evaluating the association between exposure to dental radiation and the thyroid cancer risk. Methods: We searched the PubMed and EMBASE databases to identify studies on dental radiation and thyroid cancer risks that were published up to September 2018. Quality of studies was assessed using the Newcastle-Ottawa scale. A fixed-effects model was used to estimate pooled odds ratios (ORs) and 95% confidence intervals (CIs) using STATA 14.0. Potential publication biases were evaluated using Egger's test and Begg's funnel plot. Results: From the literature search, we included six case-control studies in this meta-analysis. The meta-analysis using the fixed-effects model found that dental X-ray exposure was associated with 2.34 times increased risk for thyroid cancer (OR=2.34, 95% CI=1.79-3.21). There was no heterogeneity in the data (p=0.662, I2 =0%). Egger's test showed that there was no publication bias (p=0.532). Conclusions: This meta-analysis confirmed the association of dental X-ray exposure and thyroid cancer risk. The current results underscore the importance of applying safety regulations at dental clinics to protect thyroid glands during dental radiography examinations.

Mediating Effect of Innovative Behavior on the Relationship between Awareness of Nursing Manager's Leadership type in General Hospital Nurses and Future Use of Evidence-based Practice (종합병원 간호사의 간호관리자 리더십 유형 인식과 근거기반실무 적용의도와의 관계: 혁신행동의 매개효과)

  • Cho, Hyang-Sun;Kim, Yun-Hee;Kim, Hyo-Youn
    • Journal of the Korea Convergence Society
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    • v.10 no.11
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    • pp.511-521
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    • 2019
  • This study was conducted to examine the mediating effect of innovative behavior in the relationship between nurse manager's leadership and nurses' future use of evidence-based practice. Participants were 183 nurses working at general hospitals with over 500 beds in Korea. Nurse manager's transformational leadership was positively correlated with innovative behavior and nurses' future use of evidence-based practice. Innovative behavior showed partial mediating effects in the relationship between nurse manager's leadership and nurses' future use of evidence-based practice. These findings suggest that in order to enhance nurses' future use of evidence-based practice, the educational strategies to promote nurses' innovative behavior should be developed and provided in nursing field.

Research Trend Analysis of Oral Health Literacy in South Korea (구강건강 분야의 헬스리터러시 국내연구경향 분석)

  • Lee, Ju-Yul;Park, Soo-Auk
    • The Journal of Korean Society for School & Community Health Education
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    • v.21 no.1
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    • pp.33-45
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    • 2020
  • Objectives: The purpose of this study is to analyze the research trends on oral health literacy in South Korea and to suggest the direction of future research, Methods: The literatures were searched using KISS, RISS, KMBASE, KoreaMed, Nanet and NDSL. A total of 17,433 documents were retrieved by database searching. The final 34 literatures that satisfied the inclusion criteria were selected for analyzing. A content analysis was performed on 34 literatures on the topics of oral health literacy which had been published from 2012 to 2019. Results: Most of the 34 literatures, 23 articles and 11 thesises were descriptive-correlation studies, but there was no intervention study. The participants studied in the selected literatures were mostly adults followed by elderly and other groups including foreigner. More troubling sufficient samples and sampling methods were lacking at the population level. The validation of the used health literacy instruments was not sufficient. Conclusions: The unification of translation terminology for oral health literacy and the standardized instrument to test oral health literacy are needed. And to improve the level of oral health literacy, studies should be conducted using various variables. It is also necessary to develop the oral health education programs that can improve the level of oral health literacy. In the future, meta-analysis on the oral health literacy are needed for cumulating findings and drawing more reliable and general conclusions.

Dental alloplastic bone substitutes currently available in Korea

  • Ku, Jeong-Kui;Hong, Inseok;Lee, Bu-Kyu;Yun, Pil-Young;Lee, Jeong Keun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.45 no.2
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    • pp.51-67
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    • 2019
  • As dental implant surgery and bone grafts were widely operated in Korean dentist, many bone substitutes are commercially available, currently. For commercially used in Korea, all bone substitutes are firstly evaluated by the Ministry of Health and Welfare (MOHW) for safety and efficacy of the product. After being priced, classified, and registration by the Health Insurance Review and Assessment Service (HIRA), the post-application management is obligatory for the manufacturer (or representative importer) to receive a certificate of Good Manufacturing Practice by Ministry of Food and Drug Safety. Currently, bone substitutes are broadly classified into C group (bone union and fracture fixation), T group (human tissue), L group (general and dental material) and non-insurance material group in MOHW notification No. 2018-248. Among them, bone substitutes classified as dental materials (L7) are divided as xenograft and alloplastic bone graft. The purpose of this paper is to analyze alloplastic bone substitutes of 37 products in MOHW notification No. 2018-248 and to evaluate the reference level based on the ISI Web of Knowledge, PubMed, EMBASE (1980-2019), Cochrane Database, and Google Scholar using the criteria of registered or trademarked product name.

A Comparative Study of Mongolian and Korean Traditional Medicine (몽골과 한국 전통의학의 비교 연구)

  • Purevjav, Oyanga-Bileg;Ha, Won-Bae;Geum, Ji-Hye;Lee, Jung-Han
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.87-103
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    • 2021
  • Objectives The purpose of this study was to investigate the development process and describe the diagnosis methods, theories and treatments of Mongolian traditional medicine and Korean traditional medicine through literature records and prior studies. Methods Literature records and previous studies on traditional medicine of both countries were collected through various sites in Mongolia (Esan, Mongoliajol, Kok, Yumpu, Scribd, Science and Technology Foundation [STF]) and Korea (Koreanstudies Information Service System [KISS], Korea Institute of Science and Technology Information [KISTI], National Digital Science Library [NDSL], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]). Also the English database was searched through PubMed. In the case of Mongolian traditional medicine, medical books published in Mongolia were mainly referenced and used for research. Results Studying the development process, basic concepts and the system of diagnosis and treatment of the two traditional medicine, several commonalities and differences were revealed. Conclusions This study showed that the scope of diagnosis methods between Mongolian and Korean traditional medicine were slightly different, and that the medical terminology for the diagnosis method had slightly different contents from each other. Although there were many similarities in treatments of Mongolian and Korean traditional medicine, the Chuna therapy is found in Korean traditional medicine only. The basic theories constituting traditional medicine were the same, but the five-element theory used by the two countries differs in the following two factors. Mongolia uses elements of air and space as the theory of five elements, while Korea uses elements of wood and iron.

Psychosocial support interventions for women with gestational diabetes mellitus: a systematic review

  • Jung, Seulgi;Kim, Yoojin;Park, Jeongok;Choi, Miyoung;Kim, Sue
    • Women's Health Nursing
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    • v.27 no.2
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    • pp.75-92
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    • 2021
  • Purpose: This study aimed to analyze the content and effectiveness of psychosocial support interventions for women with gestational diabetes mellitus (GDM). Methods: The following databases were searched with no limitation of the time period: Ovid-MEDLINE, Cochrane Library, Ovid-Embase, CINAHL, PsycINFO, NDSL, KoreaMed, RISS, and KISS. Two investigators independently reviewed and selected articles according to the predefined inclusion/exclusion criteria. ROB 2.0 and the RoBANS 2.0 checklist were used to evaluate study quality. Results: Based on the 14 selected studies, psychosocial support interventions were provided for the purpose of (1) informational support (including GDM and diabetes mellitus information; how to manage diet, exercise, stress, blood glucose, and weight; postpartum management; and prevention of type 2 diabetes mellitus); (2) self-management motivation (setting goals for diet and exercise management, glucose monitoring, and enhancing positive health behaviors); (3) relaxation (practicing breathing and/or meditation); and (4) emotional support (sharing opinions and support). Psychosocial supportive interventions to women with GDM lead to behavioral change, mostly in the form of self-care behavior; they also reduce depression, anxiety and stress, and have an impact on improving self-efficacy. These interventions contribute to lowering physiological parameters such as fasting plasma glucose, glycated hemoglobin, and 2-hour postprandial glucose levels. Conclusion: Psychosocial supportive interventions can indeed positively affect self-care behaviors, lifestyle changes, and physiological parameters in women with GDM. Nurses can play a pivotal role in integrative management and can streamline the care for women with GDM during pregnancy and following birth, especially through psychosocial support interventions.