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Comparative Estrogenic Effects of Yak-Kong and Soy Bean on the Proliferation of Human Osteoblastic Cell Line, MG-63 (MG 63 조골세포에서 약콩과 대두의 천연 에스트로겐 효과 비교)

  • 조윤희;박수진;신호정;장기효;강순아;조여원
    • Journal of Nutrition and Health
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    • v.34 no.8
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    • pp.905-911
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    • 2001
  • Phytoestrogens, especially soy-derived isoflavones, are receiving great scrutiny as a food supplement for preventing hormone dependent diseases such as cardiovascular diseases, cancer, and osteoporosis. These beneficial effects of phytoestrogens are caused by functioning as partial agonists or antagonists of estrogens. In contrast to the common usage of soy bean, Yak-kong(Rhynchosia Molubilis ; ) has been used as supplements of estrogen fir preventing postmenopausal osteoporosis in Oriental medicine. To investigate estrogenic effects of Yak-kong and soy bean on the proliferation of MG-63 osteoblastic cells, each bean was extracted with 70% methanol and dried by freeze-drying. Yak-kong treatment of MG-63 cells resulted in an increase of cell proliferation to a maximum of 76% compared to 68% of soy bean treatment. Treatment of MG-63 cells with Yak-kong extract also resulted in an increase of transactivation of an ERE(estrogen response element)-luciferase reporter plasmid and IGF-I expression selectively. Despite increased effects of both bean treatments on the expression of estrogen receptor $\alpha$(ER$\alpha$) and $\beta$(ER$\beta$), soy bean treatment decreased transactivation of an ERE-luciferase reporter plasmid and did not further enhance IGF-I expression. Together, our data demonstrates that the greater estrogenic response of Yak-kong extract for MG-63 cell proliferation is mediated by ER derived transactivation of ERE and selective induction of IGF-I expression.

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Bright and Efficient Electrophosphorescence from Polymer Based LED

  • Xie, Zhiliang;Qiu, Chengfeng;Peng, Huajun;Chen, Haiying;Wong, Man;Tang, Ben Zhong;Kwok, Hoi Sing
    • 한국정보디스플레이학회:학술대회논문집
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    • 2003.07a
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    • pp.984-987
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    • 2003
  • The electrophosphorescent emission properties were investigated in polymer light-emitting diodes (PLEDs) based on a poly(9-vinylcarbazole) (PVK) doped with a green phosphorescent dye of fac-tris(2-phenylpyridine) iridium (III) [$Ir(ppy)_3$]. A green light peaked at 516 nm was emitted from devices with a configuration of ITO/PEDOT:PSS/PVK:$Ir(ppy)_{3}$/BCP/$Alq_{3}$/LiF/Al. The optimal doping concentration of $Ir(ppy)_{3}$ in PVK was found at 2% by weight, under which maximum current efficiency of 24.3 cd/A and peak external quantum efficiency of 6.8% were achieved at the high luminance of 4240 $cd/m^{2}$. The external quantum efficiency of 5% and current efficiency of 18 cd/A can be sustained even at the very high luminance of 35000 $cd/m^{2}$.

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Regulating Natural Lighting and Ventilation of Residential Buildings in Hong Kong Policy Implications for High-rise, High-density Housing Environments in South Korea

  • Seo, Bokyong;Kim, Sung-Hwa;Lee, Jae-Hoon
    • Architectural research
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    • v.16 no.3
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    • pp.81-92
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    • 2014
  • This study discusses the features of the lighting and ventilation regulations for residential buildings in Hong Kong. Given the compact built environment and public concerns about the environmental quality of housing, various lighting and ventilation regulations have been enacted in Hong Kong. The application of building regulations on the micro scale and incentive systems on the macro scale are present, and the governments' calls for more active participation of the private sector and use of the building environmental assessment tools were also noted. Unlike South Korea, however, Hong Kong was found to adopt more performance-based standards, consider the external factors of the lighting and ventilation conditions together with the indoor elements, and provide specific design guidelines. Notwithstanding the different climatic conditions and socio-political contexts of Hong Kong and South Korea, these findings provide some policy implications for the South Korean government in its efforts to achieve a healthy environment for high-rise, high-density housing. It is suggested that the South Korean government adopt more on-site measurement methods to reflect the environmental conditions accurately and broaden the scope and scale of the implementation of the lighting and ventilation regulations with more specific, practical planning and design guidelines.

Life-cycle Cost Analysis of Using Rainwater Harvesting Systems in Hong Kong Residential Buildings (홍콩 주거건물에서 우수활용시스템의 생애주기비용분석)

  • Gao, Xing;Kim, Youngchul;Lee, Hyun Woo
    • Journal of the Korean housing association
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    • v.25 no.3
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    • pp.53-62
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    • 2014
  • This paper investigates whether the use of Rainwater Harvesting Systems (RWHSs) to provide water for washing machines in Hong Kong residential buildings would be financially attractive. In such systems, rainwater is accumulated and reused for doing laundry, garden irrigation, flushing toilets, and even drinking. Thus, the analysis of RWHSs' financial feasibility is essential for construction projects. RainCycle is used to validate financial feasibility, considering particular circumstances and data relevant to the Hong Kong context. A range of different scenarios by adjusting three factors are evaluated: catchment area, water demand, and discount rate. It is suggested that $2,000m^2$ would be a suitable catchment area in a typical Hong Kong residential building and it is demonstrated how water demand and discount rate influence the financial performance of RWHSs. In particular, the financial performance of RWHSs is sensitive to discount rates. The results suggest that the RWH system would be worthwhile for buildings with a lower number of floors, but would barely achieve financial validation in Hong Kong's super high-rise residential buildings.

The Mathematical Knowledge of Elementary School Teachers: A Comparative Perspective

  • Wong, Ngai-Ying;Rowland, Tim;Chan, Wing-Sum;Cheung, Ka-Luen;Han, Ngai-Sze
    • Research in Mathematical Education
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    • v.14 no.2
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    • pp.173-194
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    • 2010
  • This study examines the differences and similarities of mathematics teachers' subject matter knowledge among England, the Chinese mainland and Hong Kong. Data were collected from a ten-item test in the SKIMA subject matter audit instrument [Rowland, T.; Martyn, S.; Barber, P. & Heal, C. (2000). Primary teacher trainees' mathematics subject knowledge and classroom performance. In: T. Rowland & C. Morgan (eds.), Research in Mathematics Education, Volume 2 (pp.3-18). ME 2000e.03066] from over 500 participants. Results showed that participants from England performed consistently better, with those from Hong Kong being next and then followed by those from the Chinese mainland. The qualitative data revealed that participants from Hong Kong and the Chinese mainland were fluent in applying routines to solve problems, but had some difficulties in offering explanations or justifications.

Cross-Cultural Study on the Pregnant and Childbirth Practices in Mother-Grandmother Generations of Korea, Hong-Kong, and the United States (임신 및 출산 풍습에 관한 비교문화연구: 한국, 홍콩 및 미국의 어머니-할머니 세대를 중심으로)

  • 민하영;유안진
    • Journal of the Korean Home Economics Association
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    • v.41 no.4
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    • pp.157-168
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    • 2003
  • This study was to investigate differences or similarities in pregnant and childbirth practices of Korea, Hong Kong and the United States and of mother-grandmother generations in each culture. The subjects were young mothers(YM) have baby from 2 to 2.5 years and their mothers or mothers-in-law(GM) in Korea(YM=118, GM=118), Hong Kong(YM=126, GM=78) and the United States(YM=105, GM=105). The subjects answered the questionnaires on pregnant and childbirth practices were constructed by specialists of child study in Korea, Hong Kong and the United States. Statistical analyses were by Frequencies, Percentages, Crosstabs, One-wav ANOVA, Scheffe' test, t-test. The results of this study were as follows. 1. Mother and grandmothers of Korea more tended to believe in supernatal being of pregnancy, to expect son, to eat a resortive and a food to help conceive, to inhibit attending a funeral at the time of childbearing, to practice fetal education than of Hong Kong and the United States did. 2. Relating sexual intercourse at the time of ovulation, maternal health care during the pregnancy, childbirth in hospital, husband's being in the hospital waiting room when their wife gave birth were much more prevailant in mothers than grandmothers did in Korea and Hong Kong.

Hong Kong Chinese Breast Cathexis and Brassiere Design Preferences (홍콩 성인 여성의 유방에 대한 카텍시스 및 브래지어 선호도 연구)

  • Cha, Su-Joung;Shin, Kristina
    • The Research Journal of the Costume Culture
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    • v.19 no.4
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    • pp.780-793
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    • 2011
  • This study investigates the breast cathexis and brassiere design preferences of Chinese citizens living in Hong Kong in order to provide marketing intelligence for bra manufacturers whose target customers are from this group of potential customers. A questionnaire composed of questions concerning breast shape evaluations, brassiere design preferences, and brassiere purchase and wear practices was administered to 165 Hong Kong Chinese female undergraduates(N=165). For an analysis of our data, we used the SPSS program(version 14.0). The results indicate that a majority of Hong Kong Chinese female undergraduates perceive their breasts as 'slightly smaller than normal' (n=59, 35.8%) or 'normal'(n=78, 47.3%) in volume, and 'conical'(n=77, 46.7%) or 'flat'(n=46, 27.9%). The results also suggest that Hong Kong Chinese women possess positive breast cathexis, with only a third of the respondents reporting dissatisfaction with their breasts. Women with dome-shaped breasts expressed the most positive breast cathexis, followed by those with cone-shaped breasts. The results also show that Hong Kong Chinese typically purchase 2 brassieres per year, which is a lower purchasing rate than their counterparts in Korea(Cha & Sohn, 2010) and Taiwan(ICT Life Style Research Center, 2004). The findings also demonstrate that the preferred brassiere color is black(57%), unlike in Korea, where women prefer skin-colored brassieres.

A Study on Environmental Applications of Subway Line Color as Place Indicating Cues - Focused on Subway Transfer Stations of Seoul and Hong Kong - (장소지시단서로서 지하철 노선색 활용에 관한 연구 - 서울과 홍콩의 지하철환승역 사례를 중심으로 -)

  • Park, Hey-Kyung
    • Korean Institute of Interior Design Journal
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    • v.18 no.6
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    • pp.229-238
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    • 2009
  • Currently, subway is becoming a major part of transportation and living environment in large cities such as Seoul or Hong Kong. As the numbers of subway lines and stations increase, visual cues indicating places are needed for users with various destinations, and environmental colors as well as line colors can be expected as effective informations for easy wayfinding. The purpose of this study is to understand the current color applications in terms of creating regional differentiation and informing subway lines in the transfer stations of Seoul and Hong Kong, by field investigation. The investigation has been proceed on 24 transfer stations from February to April, 2009 by taking photos and measuring environmental colors using Minolta spectrophotometer CM-2600d. As a result, regional differentiation in color application appeared generally low in both Seoul and Hong Kong but various 'hues' differing each station are used in Hong Kong, compared to limited use of 'hues' in Seoul, In terms of 'value', the rate of Seoul appeared lightly higher than that of Hong Kong, and the use of medium high rate of 'saturation' of main and secondary colors are shown as a remarkable character of Hong Kong.

Early-life exposure to endocrine disrupting chemicals associates with childhood obesity

  • Yang, Chunxue;Lee, Hin Kiu;Kong, Alice Pik Shan;Lim, Lee Ling;Cai, Zongwei;Chung, Arthur C.K.
    • Annals of Pediatric Endocrinology and Metabolism
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    • v.23 no.4
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    • pp.182-195
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    • 2018
  • Increasing prevalence of childhood obesity poses threats to the global health burden. Because this rising prevalence cannot be fully explained by traditional risk factors such as unhealthy diet and physical inactivity, early-life exposure to endocrine disrupting chemicals (EDCs) is recognized as emerging novel risk factors for childhood obesity. EDCs can disrupt the hormone-mediated metabolic pathways, affect children's growth and mediate the development of childhood obesity. Many organic pollutants are recently classified to be EDCs. In this review, we summarized the epidemiological and laboratory evidence related to EDCs and childhood obesity, and discussed the possible mechanisms underpinning childhood obesity and early-life exposure to non-persistent organic pollutants (phthalates, bisphenol A, triclosan) and persistent organic pollutants (dichlorodip henyltrichloroethane, polychlorinated biphenyls, polybrominated diphenyl ethers, per- and polyfluoroalkyl substances). Understanding the relationship between EDCs and childhood obesity helps to raise public awareness and formulate public health policy to protect the youth from exposure to the harmful effects of EDCs.

POTENTIAL PROBLEMS OF RUNNING BUILDING MAINTENANCE PROJECTS IN CONSTRUCTION

  • Edmond W.M. Lam;Albert P.C. Chan;Daniel W.M. Chan
    • International conference on construction engineering and project management
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    • 2009.05a
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    • pp.856-863
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    • 2009
  • The problem of urban decay in Hong Kong has drawn much attention of both practitioners and academics. Poorly managed buildings not just give a negative image to the Pearl of the Orient in the region, but also pose potential risk hazards to the health and safety of the general public. While it is necessary to devise a comprehensive plan on redevelopment and urban planning, preserving the existing buildings to maintain their conditions for habitation can be a short-term option to safeguard quality standard. With the increasing number of ageing buildings in Hong Kong, a lot of research efforts have been devoted to managing repair and maintenance projects properly (for example those initiated and funded by the Construction Industry Institute, Hong Kong; and the current study financially supported by The Hong Kong Polytechnic University). Given the short duration and more diversified nature of work, building repair and maintenance works are found to be more difficult to monitor and regulate when compared with new works. This paper aims to provide a comprehensive analysis on the problems of running building maintenance projects. An extensive review of contemporary literature was firstly conducted, which forms a solid basis for developing an empirical study on the problems and difficulties of running building maintenance projects from the viewpoints of industrial practitioners with a view to formulating effective strategies for managing maintenance projects successfully.

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