• 한국IT서비스학회:학술대회논문집
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• 한국IT서비스학회 2006년도 추계학술대회
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• pp.593-599
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• 2006

Including technical device and general information system, the information-technical(IT) system is defined as the technical system for acquiring, processing, storing and transferring information to a person. This paper presents Knowledge-based Heuristic Evolution Model for creating the advanced information-technical system. This Evolution Model is derived from the historical review on definition of evolution, the research on the architecture of the general IT system, history of IT system, technology innovation theory and multi-case study research. The evolution model is applicable to the conceptual creation of the advanced product in R&D organization requiring development methodologies like rapid-prototyping to develop next generation product. For the detailed theoretical construction and practical application of Evolution Model, the case study research based on action research is performed. the object of the case study is mobile device, especially mobile hand-held phone. Thus, we obtain the Evolution Model for creating the advanced information-technical system.

• Proceedings of the Korea Information Processing Society Conference
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• 한국정보처리학회 2019년도 추계학술발표대회
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• pp.898-900
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• 2019

SPARQL(SPARQL Protocol and RDF Query Language)은 지식 베이스를 위한 표준 시맨틱 질의 언어이다. 최근 인공지능 분야에서 지식 베이스는 질의 응답 시스템, 시맨틱 검색 등 그 활용성이 커지고 있다. 그러나 SPARQL 과 같은 질의 언어를 사용하기 위해서는 질의 언어의 문법을 이해하기 때문에, 일반 사용자의 경우에는 그 활용성이 제한될 수밖에 없다. 이에 본 논문은 신경망 기반 기계 번역 기술을 활용하여 자연어 질의로부터 SPARQL 을 생성하는 방법을 제안한다. 우리는 제안하는 방법을 대규모 공개 지식 베이스인 Wikidata 를 사용해 검증하였다. 우리는 실험에서 사용할 Wikidata 에 존재하는 영화 지식을 묻는 자연어 질의-SPARQL 질의 쌍 20,000 건을 생성하였고, 여러 sequence-to-sequence 모델을 비교한 실험에서 합성곱 신경망 기반의 모델이 BLEU 96.8%의 가장 좋은 결과를 얻음을 보였다.

• Journal of the Korean Institute of Intelligent Systems
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• 제5권4호
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• pp.18-32
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• 1995

Fuzzy rules, developed by experts thus far, may be often inconsistent and incomplete. This paper proposes a new methodology for automatic generation of fuzzy rules which are nearly complete and not inconsistent. This is accomplished by simulating a knowledge gathering process of humans from control experiences. This method is simpler and more efficient than existing ones. It is shown through simulation that our method even generates better rules than those generated by experts, under fine tuned parameters.

• Dementia and Neurocognitive Disorders
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• 제17권4호
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• pp.131-136
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• 2018

Alzheimer's disease (AD) related genes have been elucidated by advanced genetic techniques. Familial autosomal dominant AD genes founded by linkage analyses are APP, PSEN1, PSEN2, ABCA7, and SORL1. Genome-wide association studies have found risk genes such as ABCA7, BIN1, CASS4, CD33, CD2AP, CELF1, CLU, CR1, DSG2, EPHA1, FERMT2, HLA-DRB5-HLA-DRB1, INPP5D, MEF2C, MS4A6A/MS4A4E, NME8, PICALM, PTK2B, SLC24A4, SORL1, and ZCWPW1. ABCA7, SORL1, TREM2, and APOE are proved to have high odds ratio (>2) in risk of AD using next generation sequencing studies. Thanks to the promising genetic techniques such as CRISPR-CAS9 and single-cell RNA sequencing opened a new era in genetics. CRISPR-CAS9 can directly link genetic knowledge to future treatment. Single-cell RNA sequencing are providing useful information on cell biology and pathogenesis of diverse diseases.

• The Journal of Korea Robotics Society
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• 제14권4호
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• pp.348-356
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• 2019

The backdrivable servovalve is a desirable component for force and interaction control of hydraulic actuation systems because it provides direct force generation mechanical impedance reduction by its own inherent backdrivability. However, high parametric uncertainty and friction effects inside the hydraulic actuation system significantly degrade its advantage. To solve this problem, this letter presents a disturbance-adaptive robust internal-loop compensator (DA-RIC) to generate ideal interactive control performance from the backdrivable-servovalve-based system. The proposed control combines a robust internal-loop compensator structure (RIC) with an explicit disturbance estimator designed for asymptotic disturbance tracking, such that the controlled system provide stable and ideal dynamic behavior for impedance control, while completely compensating the disturbance effects. With the aid of a backdrivable servovalve, we show that the proposed control structure can be implemented based on a simplified nominal model, and the controller enables implementation without accurate knowledge of the target system parameters and disturbances. The performance and properties of the proposed controller are verified by simulation and experiments.

• Korean Journal of Biological Psychiatry
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• 제28권1호
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• pp.1-6
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• 2021

Pharmacogenetics is opening a new era of precision medicine in psychiatry. Drug-metabolizing enzymes are characterized by genetic polymorphisms, which render a large portion of variability in individual drug metabolism. Dose adjustment based on pharmacogenetics knowledge is a first step to translate pharmacogenetics into clinical practice. However, diverse factors including cost-effectiveness should be addressed to provide clinical recommendation. To address current challenges in pharmacogenetics testing in psychiatry, this review provides an update regarding genotyping (SNP analysis, array, and next-generation sequencing), genotype-phenotype correlations, and cost-effectiveness. The current updates on pharmacogenetics in psychiatry will provide guidance for both clinician and researchers to have a consensus in harmonizing efforts to advance the pharmacogenetics field in a part of precision medicine in psychiatry.

• The Transactions of The Korean Institute of Electrical Engineers
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• 제68권1호
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• pp.8-12
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• 2019

Combined Cycle Unit(CC) generates the primary power from the Gas Turbine(GT) and supplies the remaining heat of the GT to the Steam Turbine(ST) to generate the secondary power from the ST. It plays a major role in terms of energy efficiency and Load Frequency Control(LFC). Incremental Heat Rate(IHR) curves of economic dispatch(ED) of CC is applied differently by GT/ST combination. But It is practically difficult because of performance test by all combinations. This paper suggests a reasonable method for estimating IHR curves for partial combinations(1:1~(N-1):1) using IHR curves when operating with GT alone(1:0) and with all(N:1) combinations of CC.

• Proceedings of the Korean Society for Information Management Conference
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• 한국정보관리학회 2013년도 제20회 학술대회 논문집
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• pp.101-104
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• 2013

본 연구에서는 웹 환경에 적합한 서지 기술을 위해 LC에서 개발한 BIBFRAME을 분석하고, BIBFRAME이 개방형 서지 데이터의 생성에 적합한지를 검토하였다. 그리고 BIBFRAME의 등장 배경 및 특징을 FRBR 모형과 비교하였다. 그 결과 BIBRAME은 1)서지 객체의 지적 내용과 물리 매체를 구분하고 있었는데, FRBR의 제1그룹보다 단순한 구조를 지니고 있었다. 2) 인명전거와 주제전거를 포함하는 넓은 개념으로 전거를 정의하고 있었으며, 서지데이터 작성자의 관점과 이용자의 관점을 함께 고려하였다. 3) 다양한 외부 데이터와의 연계 및 개별 도서관에 특화된 데이터를 추가할 수 있는 주석 개념을 도입하였다. BIBFRAME은 MARC 레코드에서 변환하거나 직접적으로 서지데이터를 작성하는 방안이 모두 가능하며, 웹 환경에 적합하다고 판단된다.

• Journal of the Korea Society of Computer and Information
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• 제24권5호
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• pp.11-17
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• 2019

In this study, we propose an ensemble engine, which is a framework for game engine optimized for visual novels genre, focusing on storytelling among various game genres. The game of Visual Nobel genre is based on multi-ending story and features branching of various scenarios according to user's choice. The proposed engine supports various multi-scenarios and multi-endings based on nodes according to the characteristics of these genres. In addition, it provides a convenient and intuitive user interface that not only enhances user immersion but also provides VR function to maximize the sense of presence. We will demonstrate the usefulness of the proposed game engine by designing the framework of a game engine suitable for this feature and actually creating variety stories automatically.

• Animal Bioscience
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• 제34권8호
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• pp.1271-1282
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• 2021

Genome-wide studies provide considerable insights into the genetic background of animals; however, the inheritance of several heritable factors cannot be elucidated. Epigenetics explains these heritabilities, including those of genes influenced by environmental factors. Knowledge of the mechanisms underlying epigenetics enables understanding the processes of gene regulation through interactions with the environment. Recently developed next-generation sequencing (NGS) technologies help understand the interactional changes in epigenetic mechanisms. There are large sets of NGS data available; however, the integrative data analysis approaches still have limitations with regard to reliably interpreting the epigenetic changes. This review focuses on the epigenetic mechanisms and profiling methods and multi-omics integration methods that can provide comprehensive biological insights in animal genetic studies.