• Asian-Australasian Journal of Animal Sciences
• /
• v.32 no.12
• /
• pp.1816-1825
• /
• 2019

Objective: We tried to analyze allele-specific expression in the pig neocortex using bioinformatic analysis of high-throughput sequencing results from the parental genomes and offspring transcriptomes from reciprocal crosses between Korean Native and Landrace pigs. Methods: We carried out sequencing of parental genomes and offspring transcriptomes using next generation sequencing. We subsequently carried out genome scale identification of single nucleotide polymorphisms (SNPs) in two different ways using either individual genome mapping or joint genome mapping of the same breed parents that were used for the reciprocal crosses. Using parent-specific SNPs, allele-specifically expressed genes were analyzed. Results: Because of the low genome coverage (${\sim}4{\times}$) of the sequencing results, most SNPs were non-informative for parental lineage determination of the expressed alleles in the offspring and were thus excluded from our analysis. Consequently, 436 SNPs covering 336 genes were applicable to measure the imbalanced expression of paternal alleles in the offspring. By calculating the read ratios of parental alleles in the offspring, we identified seven genes showing allele-biased expression (p<0.05) including three previously reported and four newly identified genes in this study. Conclusion: The newly identified allele-specifically expressing genes in the neocortex of pigs should contribute to improving our knowledge on genomic imprinting in pigs. To our knowledge, this is the first study of allelic imbalance using high throughput analysis of both parental genomes and offspring transcriptomes of the reciprocal cross in outbred animals. Our study also showed the effect of the number of informative animals on the genome level investigation of allele-specific expression using RNA-seq analysis in livestock species.

• The Korean Journal of Applied Statistics
• /
• v.28 no.2
• /
• pp.343-351
• /
• 2015

We introduce how to fit random effects models via a SRC-Stat statistical package. This package has been developed to fit double hierarchical generalized linear models where mean and dispersion parameters for the variance of random effects and residual variance (overdispersion) can be modeled as random-effect models. The estimates of fixed effects, random effects and variances are calculated by a hierarchical likelihood method. We illustrate the use of our package with practical data-sets.

• Journal of Intelligence and Information Systems
• /
• v.18 no.3
• /
• pp.137-152
• /
• 2012

In the generation of Web 2.0, as many users start to make lots of web contents called user created contents by themselves, the World Wide Web is overflowing by countless information. Therefore, it becomes the key to find out meaningful information among lots of resources. Nowadays, the information retrieval is the most important thing throughout the whole field and several types of search services are developed and widely used in various fields to retrieve information that user really wants. Especially, the legal information search is one of the indispensable services in order to provide people with their convenience through searching the law necessary to their present situation as a channel getting knowledge about it. The Office of Legislation in Korea provides the Korean Law Information portal service to search the law information such as legislation, administrative rule, and judicial precedent from 2009, so people can conveniently find information related to the law. However, this service has limitation because the recent technology for search engine basically returns documents depending on whether the query is included in it or not as a search result. Therefore, it is really difficult to retrieve information related the law for general users who are not familiar with legal terms in the search engine using simple matching of keywords in spite of those kinds of efforts of the Office of Legislation in Korea, because there is a huge divergence between everyday words and legal terms which are especially from Chinese words. Generally, people try to access the law information using everyday words, so they have a difficulty to get the result that they exactly want. In this paper, we propose a term mapping methodology between everyday words and legal terms for general users who don't have sufficient background about legal terms, and we develop a search service that can provide the search results of law information from everyday words. This will be able to search the law information accurately without the knowledge of legal terminology. In other words, our research goal is to make a law information search system that general users are able to retrieval the law information with everyday words. First, this paper takes advantage of tags of internet blogs using the concept for collective intelligence to find out the term mapping relationship between everyday words and legal terms. In order to achieve our goal, we collect tags related to an everyday word from web blog posts. Generally, people add a non-hierarchical keyword or term like a synonym, especially called tag, in order to describe, classify, and manage their posts when they make any post in the internet blog. Second, the collected tags are clustered through the cluster analysis method, K-means. Then, we find a mapping relationship between an everyday word and a legal term using our estimation measure to select the fittest one that can match with an everyday word. Selected legal terms are given the definite relationship, and the relations between everyday words and legal terms are described using SKOS that is an ontology to describe the knowledge related to thesauri, classification schemes, taxonomies, and subject-heading. Thus, based on proposed mapping and searching methodologies, our legal information search system finds out a legal term mapped with user query and retrieves law information using a matched legal term, if users try to retrieve law information using an everyday word. Therefore, from our research, users can get exact results even if they do not have the knowledge related to legal terms. As a result of our research, we expect that general users who don't have professional legal background can conveniently and efficiently retrieve the legal information using everyday words.

• Proceedings of the KSRS Conference
• /
• v.1
• /
• pp.297-300
• /
• 2006

The knowledge of fuel load and composition is important for planning and managing the fire hazard and risk. However, fuel mapping is extremely difficult because fuel properties vary at spatial scales, change depending on the seasonal situations and are affected by the surrounding environment. Remote sensing has potential of reduction the uncertainty in mapping fuels and offers the best approach for improving our abilities. This paper compared the results of object-oriented classification to a pixel-based classification for fuel type map derived from Hyperion hyperspectral data that could be enable to provide this information and allow a differentiation of material due to their typical spectra. Our methodological approach for fuel type map is characterized by the result of the spectral mixture analysis (SMA) that can used to model the spectral variability in multi- or hyperspectral images and to relate the results to the physical abundance of surface constitutes represented by the spectral endmembers. Object-oriented approach was based on segment based endmember selection, while pixel-based method used standard SMA. To validate and compare, we used true-color high resolution orthoimagery

• Journal of the Institute of Convergence Signal Processing
• /
• v.6 no.3
• /
• pp.112-119
• /
• 2005

In this paper, a model of neural circuit was proposed, which abstracts the depth information in two images gotten from right and left retinas. The proposed neural circuit corresponds to binocular stereo vision based on psychologic and physiological knowledge, and we examine a restoration method of three-dimensional surface. In case of drawing a disparity based on characteristics of images, we can not abstract the depth information correctly if resemblant characteristics are repeated on the boundary region of an object. A binocular disparity is decided in a model of neural circuit by abstraction, synthesis, and correction of a disparity. And we propose a method which restores three-dimensional shape by correcting a depth information, and also restores a three-dimensional surface by mapping a left input image on the restored three-dimensional shape. And we confirmed that the computation time for disparity abstraction can be greatly reduced through the simulation.

• The Transactions of the Korean Institute of Electrical Engineers A
• /
• v.48 no.11
• /
• pp.1382-1387
• /
• 1999

This paper presents an optimal fuzzy power system stabilizer to damp out low frequency oscillation. So far fuzzy controllers have been applied to power system stabilizing controllers due to its excellent properties on the nonlinear systems. But the design process of fuzzy logic power system stabilizer requires empirical and heuristic knowledge of human experts as well as many trial-and-errors in general. This paper presents and optimal design method of the fuzzy logic stabilizer using the genetic algorithm. Non-symmetric membership functions are optimally tuned over an evaluation function. The present inputs of fuzzy stabilizer are torque angle error and the change of torque angle error without loss of generality. The coding method used in this paper is concatenated binary mapping. Each linguistic fuzzy variable, defined as the peak of a membership function, is assigned by the mapping from a minimum value to a maximum value using eight bits. The tournament selection and the elitism are used to keep the worthy individuals in the next generation. The proposed system is applied to the one-machine infinite-bus model of a power system, and the results showed a promising possibility.

• Korean Journal of Remote Sensing
• /
• v.21 no.5
• /
• pp.393-404
• /
• 2005

As multi-source spatial data fusion mainly deal with various types of spatial data which are specific representations of real world with unequal reliability and incomplete knowledge, proper data representation and uncertainty analysis become more important. In relation to this problem, this paper presents and applies an advanced data representation methodology for different types of spatial data such as categorical and continuous data. To account for the uncertainties of both categorical data and continuous data, fuzzy boundary representation and smoothed kernel density estimation within a fuzzy logic framework are adopted, respectively. To investigate the effects of those data representation on final fusion results, a case study for landslide hazard mapping was carried out on multi-source spatial data sets from Jangheung, Korea. The case study results obtained from the proposed schemes were compared with the results obtained by traditional crisp boundary representation and categorized continuous data representation methods. From the case study results, the proposed scheme showed improved prediction rates than traditional methods and different representation setting resulted in the variation of prediction rates.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.9 no.4
• /
• pp.165-175
• /
• 2006

The discussion about capacity development (CD) has been spotlighted as significant drivers for sustainable development in recent years. Multi-dimensional natures of capacities would lead to various definitions of CD in international institutes and organizations. CD is perceived as an endogeneous process to improve actionable learning and knowledge, but most of core capacities still remain abstract notion and might be unreliable in sustainable development (SD). The paper first explicates international perspectives of CD in association with SD. An agent-based model is especially proposed to portray more details of CD. It illuminates the role of assets (or capitals, resources) in agents to impact on ingredients of CDs that are drivers or enablers for improvement of SD. A definition of sustainable capacity development is firstly articulated in international society and its conceptual framework is also creatively designed to assist concerned international organizations. The paper concludes by proposing practical spatial asset mapping linking to agent-based organizational capacity as a tool for measuring sustainable capacity development.

• Proceedings of the Botanical Society of Korea Conference
• /
• 1995.07a
• /
• pp.57-86
• /
• 1995

Molecular mapping of plant genomes has progressed rapidly since Bostein et al.(1980) introduced the idea of constructing linkage maps of human genome based on restriction fragment length polymorphism (RFLP) markers. In recent years, the development of protein and DNA markers has stimulated interest for the new approaches to plant improvement. While classical maps based on morphological mutant markers have provided important insights into the plant genetics and cytology, the molecular maps based on molecular markers have a number of inherent advatages over classical genetic maps for the applications in genetic studies and/or breeding schemes. Isozymes and DNA markers are numerous, discrete, non-deleterious, codominant, and almost entirely free of environmental and epistatic interactions. For these reasons, they are widely used in constructing detailed linkage maps in a number of plant species. Plant breeders improve crops by selecting plants with desirable phenotypes. However a plant's phenotyes is often under genetic control, positioning at different "quantitative trait loci" (QTLs) together with environmental effects. Molecular maps provide a possible way to determine the effect of the individual gene that combines to produce a quantitative trait because the segregation of a large number of markers can be followed in a single genetic cross. Using market-assisted selection, plants that contain several favorable genes for the trait and do not contain unfavourable segments can be obtained during early breeding processes. Providing molecular maps are available, valuable data relevant to the taxonomic relationships and chromosome evolution can be accumulated by comparative mapping and also the structural relationships between linkage map and physical map can be identified by cDNA sequencing. After constructing high density maps, it will be possible to clone genes, whose products are unknown, such as semidwarf and disease resistance genes. However, much attention has to be paid to level-up the basic knowledge of genetics, physiology, biochemistry, plant pathology, entomology, microbiology, and so on. It must also be kept in mind that scientists in various fields will have to make another take off by intensive cooperation together for early integration and utilization of these newly emerging high-techs in practical breeding. breeding.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2004.03b
• /
• pp.113-120
• /
• 2004

Grouting works in fractured rocks have been performed to reinforce the underground and/or to block ground water flow at the foundation site of dam, bridge and so on. For the efficient grouting design, a prior knowledge of the fracture pattern of underground area to be grouted in very important. For the practical use, aperture sizes of open fractures that will be filled up with grouting materials will be kind of valuable information. Thus, the main purpose of this study is to develop a new technique (so called "GenFT") enable to form a three dimensional image of fracture aperture density distribution from Televiewer data. For this, the study is to focus on dealing with (1) estimating aperture size of each fracture automatically from Televiewer time image, (2) mapping extension of fracture planes on a given section, (3) evaluating aperture density distribution on the section by using both aperture size and fracture face mapping result of each fracture, (4) developing an algorithm that can transfer the previous results to any arbitrary(vertical and/or horizontal) section around the borehole. Since 3D imaging means "a strategy used to form an image of arbitrarily subdivided 2D sections with aperture density distribution", it will help avoid ambiguities of fracture pattern interpretation and hence will be of practical use not only for the design and assessment of grouting works but also for various engineering works. Examples of fields experiments are illustrated. It would seem that this technique might lead to reflecting future trend in underground survey.