• Title/Summary/Keyword: Knowledge Discovery

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Systematic Review of Korean Medicine for the Treatment of Sixth Cranial Nerve Palsy (외전신경마비의 한의학 치료에 대한 체계적 문헌 고찰)

  • Won, Seo-young;Kim, Min-ji;Cha, Ji-yun;Jung, Eun-sun;Cho, Hyun-kyoung;Yoo, Ho-ryong;Seol, In-chan;Kim, Yoon-sik
    • The Journal of Internal Korean Medicine
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    • v.40 no.3
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    • pp.409-424
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    • 2019
  • Objectives: This research aimed to confirm the efficacy of oriental medicine in sixth cranial nerve palsy and to evaluate the quality of the studies. Methods: Using the medical subject heading (MeSH) keywords "abducens nerve palsy", "abducens nerve paralysis", "sixth nerve palsy", "herbal medicine", "Chinese medicine", "oriental medicine" and "acupuncture", we collected the research papers through an electronic database search in Oriental Medicine Advanced Searching Integrated System (OASIS), National Discovery for Science Leaders (NDSL), PubMed, Cochran Library, and China National Knowledge Infrastructure (CNKI). Results: A total of 136 papers were searched from the databases. Among these, 15 case reports and 8 randomized controlled trials (RCTs) met our criteria. 17 articles were found on the use of acupuncture as the main intervention, 11 on the use of herbal medicine as the main intervention, and 9 on the use of electroacupuncture as the main intervention. The frequently used acupoints were LI4, EX-HN5, GB1, BL2, TE23, LR3, BL1, ST2, GB20, and ST36. All 23 studies confirmed the efficacy of Korean medicine. According to the assessment using the risk of bias, the overall quality of the RCTs was low. Conclusions: Twenty-three papers suggested that Korean medicine treatment for abducens nerve palsy was effective in many cases. Analyzing the potential bias was difficult.

Review of Korean Medicine Treatments for Purpura and Vasculitis in Korean Journals (혈관염 및 자반증의 한의학적 치료에 대한 국내 임상 논문 분석)

  • Kang, Dong-Won;Park, Jung-Gun;Han, Chang-Yi;Kim, Kyu-Seok;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.3
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    • pp.116-135
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    • 2019
  • Objectives : The purpose of this study is to analyze how purpura and vasculitis have been treated with Korean medicine and potentially to present with future direction of research and treatment. Methods : We searched clinical studies from the Korean databases including Oriental medicine Advanced Searching Integrated System(OASIS), Korean Traditional Knowledge Portal(KTKP), National Discovery for Science Leader(NDSL), Research Information Sharing Service(RISS), using keywords related to "Purpura" and "Vasculitis" from January 2000 to May 2019. Results : A total of 20 studies were selected for analysis. More than half of the patients provided with detailed information were under 19 year-olds, and upper respiratory infection, stress and fatigue, seasonal factor were among the most frequently stated as predisposing factors. Among many treatment modalities, herbal medicine was the most frequently used, followed by acupuncture and herbal acupuncture. 23 basic herbal medicine formulas were retrieved from 20 articles, most frequently used being Guibi-tang(歸脾湯加味), Samul-tang(四物湯加味) and Yukmijihwang-tang(六味地黃湯加味). In total, 122 Korean medicine herbs were used, most frequently used herbs being Glycyrrhizae Radix et Rhizoma(甘草), Angelicae Gigantis Radix(當歸), Poria Sclerotium(茯?) and Paeoniae Radix(芍藥). By its category, herbs were mostly classified into Tonyfying and replenishing medicinal(補益藥), Heat-clearing medicinal(淸熱藥) and Exterior-releasing medicinal(解表藥). Patients with total treatment period of 3 months or under were 2/3 of all cases provided with detailed information. Follow up periods were short in general with only 6 cases of over 6 months. The primary motive of patients to receive Korean medicine treatments was unresponsiveness or adverse effects of western medication. Conclusion : Through this literature review, we could find out tendencies of Korean medicine treatments of purpura and vasculitis up to date and some points that may have clinical significance.

Scientific Significances of the Seongryu Cave (Natural Monument No. 155) (성류굴(천연기념물 제155호)의 과학적 중요성)

  • Kim, Lyoun(Ryeon);Woo, Kyung Sik;Kim, Bong Hyeon;Park, Jae Suk;Park, Hun Young;Jeong, Hae Jeong;Lee, Jong Hee
    • Korean Journal of Heritage: History & Science
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    • v.43 no.1
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    • pp.236-259
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    • 2010
  • The examination of sediment distribution in Seongryu Cave shows existence of rocks contrasting with Joseon Supergroup contrary to existing knowledge. Contrasting especially with the Taeback Group, Daegi Formation, Hwajeol Formation, and Dongjeom Formation has been observed. Unlike Taeback area where Dumugol Formation and Makgol Formation are observed on top of Dongjeom Formation, the rocks of this area are not clear in its separation between the two, so that it was named Geunnam Formation. Seongryu Cave has been developed in this Ordovician Geunnam Formation of the Joseon Supergroup. The cave, mostly horizontal, runs in the NE-SW direction, and contains three lakes. The main passage and branches are about 330 m and 540 m, respectively, making the total length of the cave about 870 m (show cave area = 270 m). Through underwater examination, about 85 m-long underwater passage was newly discovered. Various speleothem such as soda straw, stalactite, stalagmite, column, flowstone, rimston, cave shield, cave coral, curtain, bacon sheet, cave pearl, cave flower, helictite and calcite raft can be found in the cave. There are sections with constant flow of cavern water, but the majority of cavern water in the cave come from the ceiling. The most important discovery in this study is the presence of various speleothem in the submerged part of cave passages. Traces of corrosion and/or erosion can be observed in the speleothem in the submerge passage.

Analysis of Case Studies of Treating Atopic Dermatitis - focusing on Korean Herbal Medicine Used in Cases - (아토피 피부염 증례 연구 분석 - 한약 처방을 중심으로 -)

  • Han, Chang-Yi;Park, Jung-Gun;Kang, Dong-Won;Park, So-Young;Kim, Bong-Hyun;Kim, Yoon-Bum;Kim, Kyu-Seok
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.3
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    • pp.151-163
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    • 2019
  • Objectives : The purpose of this study is to investigate the use of herbal medicine for the treatment of atopic dermatitis in cases and to find the general tendency of herbal medicine treatment and to establish the primary treatment direction of Atopic dermatitis. Methods : In the domestic databases, Oriental medicine Advanced Searching Integrated System(OASIS), Korean Traditional Knowledge Portal(KTKP), National Discovery for Science Leader(NDSL), Research Information Sharing Service(RISS), we selected among the papers published in the last 20 years using search terms related to "Atopic dermatitis & Cases". Reports based on Sasang constitutional medicine and Six meridian pattern identification were excluded and a total of 21 papers were finally selected. Results : 113 herbal medicines were retrieved from 21 papers. The most commonly used herbs are Scutellariae Radix(黃芩), Rehmanniae Radix(地黃), and Glycyrrhizae Radix et Rhizoma(甘草). Atractylodis Rhizoma(蒼朮), Akebiae Caulis(木通), Smilacis Rhizoma(土茯?), Paeoniae Radix(芍藥) used mostly when Oozing exists, Trichosanthis Radix (瓜蔞), Asparagi Radix(天門冬), Persicae Semen(桃仁), Carthami Flos(紅花) used mostly when Dryness, Lichenification, and Pigmentation exist. The average score of SCORAD index was improved after Herbal medicine treatment. Conclusion : Through this study, we could find out the tendency of herbal medicine to treat Atopic dermatitis along with Symptoms.

Frequent Origin-Destination Sequence Pattern Analysis from Taxi Trajectories (택시 기종점 빈번 순차 패턴 분석)

  • Lee, Tae Young;Jeon, Seung Bae;Jeong, Myeong Hun;Choi, Yun Woong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.3
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    • pp.461-467
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    • 2019
  • Advances in location-aware and IoT (Internet of Things) technology increase the rapid generation of massive movement data. Knowledge discovery from massive movement data helps us to understand the urban flow and traffic management. This paper proposes a method to analyze frequent origin-destination sequence patterns from irregular spatiotemporal taxi pick-up locations. The proposed method starts by conducting cluster analysis and then run a frequent sequence pattern analysis based on identified clusters as a base unit. The experimental data is Seoul taxi trajectory data between 7 a.m. and 9 a.m. during one week. The experimental results present that significant frequent sequence patterns occur within Gangnam. The significant frequent sequence patterns of different regions are identified between Gangnam and Seoul City Hall area. Further, this study uses administrative boundaries as a base unit. The results based on administrative boundaries fails to detect the frequent sequence patterns between different regions. The proposed method can be applied to decrease not only taxis' empty-loaded rate, but also improve urban flow management.

The development of the 2020 Dietary Reference Intakes for Korean population: Lessons and challenges (2020 한국인 영양소 섭취기준 제·개정: 교훈과 도전)

  • Kwon, Oran;Kim, Hyesook;Kim, Jeongseon;Hwang, Ji-Yun;Lee, Jounghee;Yoon, Mi Ock
    • Journal of Nutrition and Health
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    • v.54 no.5
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    • pp.425-434
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    • 2021
  • The discovery of the relationship between nutrients and deficiency diseases during the 100 years from the mid-1800s to the mid-1900s was a breakthrough that led to advances in the study of nutrition. The Recommended Dietary Allowances (RDA) were created as a quantitative standard for avoiding diseases caused by nutrient deficiency. In addition, a reductionism paradigm has become generally accepted among nutrition scholars in health and disease, which focused on the properties of individual nutrients, content in foods, cellular levels, and mechanisms of action. The reductionist paradigm worked very well for the prevention and treatment of malnutrition diseases. However, as the incidence of nutrient deficiencies decreased and that of chronic diseases increased, the nutrition goals have been changed to secure safe and adequate nutrient intake and to reduce chronic disease risks. Accordingly, Dietary Reference Intakes (DRIs), a set of nutrient-based reference values, were designed to replace the RDA. The revised Korean DRIs were published for 40 nutrients in 2020. However, there is still room for improvement in the reference intake levels targeted at reducing the risk of chronic disease. The reductionist approach can no longer be practical because chronic diseases are related to the interactions between multi-components in the foods and multi-targets in the body. Therefore, a second innovative leap is needed following the nutrition development breakthrough made over 100 years ago. To this end, the nutrition paradigm must evolve from reductionism to a holism approach. Cutting-edge scientific technologies, such as metabolomics, transcriptomics, microbiomics, and bioinformatics, should also be acceptable in nutrition science based on the knowledge gained from basic nutrition studies.

Oedipa's Quest and Two Americas (에디파의 탐구와 두 개의 미국)

  • Son, Dongchul
    • English & American cultural studies
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    • v.9 no.1
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    • pp.273-295
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    • 2009
  • As Oedipa Mass, the heroine of Thomas Pynchon's The Crying of Lot 49, is apparently associated with Oedipus, the hero in Sophocles' tragedy, this paper aims to show some of their similarities in quest theme and plot development as well as in the use of dramatic irony. Oedipus the King opens with a priest's pleas to relieve the Theban people from a plague and the king's promise to rid its cause by avenging the murder of the former king, as told by the oracle. Lot 49 begins as a Los Angeles law firm informs Oedipa that she is named as the executrix in her former lover Inverarity's will to sort out the mogul's estate. Ironically, however, Oedipus' investigation reveals himself to be the very cause of the national disaster, the murderer for whom he searched. Likewise, Oedipa starts her inquiry dedicating herself to make sense out of what Inverarity had left behind, only to find that the legacy was America. Sophocles and Pynchon both employ dramatic irony to provide a controlling principle for plot development in their works. In Oedipus the King, Sophocles creates mounting tension as well as distance between the reader's knowledge and the protagonist's ignorance, compressing the play's action into the moment that Oedipus discovers his real identity. For dramatic irony, however, Pynchon tends to work through authorial comments and utilize allegorical meanings of the characters' names, directing his novel at illuminating Oedipa's discovery of Inverarity's legacy as well as the meaning of Tristero, an underground postal service system. Unlike Oedipus the King that proceeds on a single line of action, Lot 49 develops in esoteric, multi-layered allusions and intricately-interrelated double strains involving Oedipa's roles as executrix and quester. At the end of Sophocles' tragedy, Oedipus stabs his eyes and decides to live in exile, realizing that, blinded, he begot his children through his mother; Oedipa comes to a painful realization that she allowed her former lover to create death-orienting America without her diversity and moral system in old times. As Oedipa now discovers herself through her search for Tristero, her tragic spirit lies in her determination to confront her binary choices between two Americas: transcendence or entropy, the Tristero possibility or Inverarity's America. Ultimately, Oedipa tries to find who will be the bidder for the Tristero forged stamps designated as lot 49, awaiting the auctioneer's cry and the "crying" of a new-born America.

A Study on the Conceptual Changes of Extra-solar Planet in University Students Using Text-Mining Techniques (텍스트마이닝을 활용한 대학생들의 외계행성 개념 변화 연구)

  • Han, Shin;Kim, Yong-Ki;Kim, Hyoungbum
    • Journal of the Korean Society of Earth Science Education
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    • v.13 no.3
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    • pp.305-316
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    • 2020
  • This study aimed to analyze the conception of an extra-solar planet perceived by university students. To conduct this, we developed an extra-solar planet education program and questionnaires which help to figure out changes between before and after the program, and then applied them to the targeted students. The results of the study are as follows. First, as to the conception of an extra-solar planet, participants understood it merely as a planet outside the solar system before they got training. However, they expanded it to the one revolving around a star that appears outside the solar system based on keywords after the training. Second, they gave brief responses regarding exploration strategies (e.g., observing the extra-solar planet by using the Doppler effect, dietary phenomenon, and gravitational lens) based on indirect experiences they encountered in the media. The responses indicated their lack of concept of the extra-solar planet exploration methods. However, their recognition of the extra-solar planet observation became concrete while students learned about the exploration of the extra-solar planet. Third, they were expanding the importance of the exoplanet observation simply beyond the discovery of extraterrestrial life to the creative process and research methods, including the solar system and the development of humanity. Fourth, they recognized that exoplanet education is necessary for curriculum as it will be able to bring about students' interest and curiosity as well as scientific knowledge if contents related to the extra-solar planet appear in the earth science curriculum.

Analysis of the Importance and Satisfaction of Viewing Quality Factors among Non-Audience in Professional Baseball According to Corona 19 (코로나 19에 따른 프로야구 무관중 시청품질요인의 중요도, 만족도 분석)

  • Baek, Seung-Heon;Kim, Gi-Tak
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.2
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    • pp.123-135
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    • 2021
  • The data processing of this study is focused on keywords related to 'Corona 19 and professional baseball' and 'Corona 19 and professional baseball no spectators', using text mining and social network analysis of textom program to identify problems and view quality. It was used to set the variable of For quantitative analysis, a questionnaire on viewing quality was constructed, and out of 270 survey respondents, 250 questionnaires were used for the final study. As a tool for securing the validity and reliability of the questionnaire, exploratory factor analysis and reliability analysis were conducted, and IPA analysis (importance-satisfaction) was conducted based on the questionnaire that secured validity and reliability, and the results and strategies were presented. As a result of IPA analysis, factors related to the image (image composition, image coloration, image clarity, image enlargement and composition, high-quality image) were found in the first quadrant, and the second quadrant was the game situation (support team game level, support player game level, star). Player discovery, competition with rival teams), game information (match schedule information, player information check, team performance and player performance, game information), interaction (consensus with the supporting team), and some factors appeared. The factors of commentator (baseball-related knowledge, communication ability, pronunciation and voice, use of standard language, introduction of game-related information) and interaction (real-time communication with the front desk, sympathy with viewers, information exchange such as chatting) appeared.

Development of Regional Problem Solving Entrepreneurship Education Program: Based on Competency-Based Curriculum Design (지역사회 문제해결형 기업가정신 교육과정 개발: 역량 기반 교육과정 설계를 기반으로)

  • Choi, Yong Seok;Part, Jong Seok;Baek, Bo Hyun
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.5
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    • pp.187-203
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    • 2022
  • As the economic, social, and environmental problems of the local community reach a serious level, our society is realizing the need to foster young talents who discover opportunities in local issues through entrepreneurship education and create social values through creative challenges. However, entrepreneurship education programs are generally focused on commerciality, so customized education programs to solve regional problems are insufficient. Therefore, this study aimed to develop a community problem-solving entrepreneurship curriculum. In this study, a competency based curriculum model was applied to develop the curriculum, and regional problem-solving entrepreneurship competencies were derived through expert advice from a total of 10 people. In the process, the Delphi methodology was additionally used to reduce the possibility of errors in the competency model. As a result of the study, a total of 23 regional problem-solving entrepreneurship competencies were confirmed, and knowledge(K) - skill(S) - attitude(A) by competency consisted of 5, 9, and 9, respectively. By applying this to Dunham's problem-solving six-step model, modular learning support measures were developed in the order of phase 1(problem discovery), phase 2(problem analysis), phase 3(plan), phase 4(measure), and phase 5(evaluation). This study is meaningful in that it integrated theory and practice by developing specific entrepreneurship curriculum and learning support measures based on the theoretical model devised in social welfare. In addition, it has implications in that it developed a regional problem-solving entrepreneurship competency model based on expert advice and proposed a specific curriculum based on this.