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http://dx.doi.org/10.6114/jkood.2019.32.3.116

Review of Korean Medicine Treatments for Purpura and Vasculitis in Korean Journals  

Kang, Dong-Won (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
Park, Jung-Gun (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
Han, Chang-Yi (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
Kim, Kyu-Seok (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
Kim, Yoon-Bum (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University)
Publication Information
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology / v.32, no.3, 2019 , pp. 116-135 More about this Journal
Abstract
Objectives : The purpose of this study is to analyze how purpura and vasculitis have been treated with Korean medicine and potentially to present with future direction of research and treatment. Methods : We searched clinical studies from the Korean databases including Oriental medicine Advanced Searching Integrated System(OASIS), Korean Traditional Knowledge Portal(KTKP), National Discovery for Science Leader(NDSL), Research Information Sharing Service(RISS), using keywords related to "Purpura" and "Vasculitis" from January 2000 to May 2019. Results : A total of 20 studies were selected for analysis. More than half of the patients provided with detailed information were under 19 year-olds, and upper respiratory infection, stress and fatigue, seasonal factor were among the most frequently stated as predisposing factors. Among many treatment modalities, herbal medicine was the most frequently used, followed by acupuncture and herbal acupuncture. 23 basic herbal medicine formulas were retrieved from 20 articles, most frequently used being Guibi-tang(歸脾湯加味), Samul-tang(四物湯加味) and Yukmijihwang-tang(六味地黃湯加味). In total, 122 Korean medicine herbs were used, most frequently used herbs being Glycyrrhizae Radix et Rhizoma(甘草), Angelicae Gigantis Radix(當歸), Poria Sclerotium(茯?) and Paeoniae Radix(芍藥). By its category, herbs were mostly classified into Tonyfying and replenishing medicinal(補益藥), Heat-clearing medicinal(淸熱藥) and Exterior-releasing medicinal(解表藥). Patients with total treatment period of 3 months or under were 2/3 of all cases provided with detailed information. Follow up periods were short in general with only 6 cases of over 6 months. The primary motive of patients to receive Korean medicine treatments was unresponsiveness or adverse effects of western medication. Conclusion : Through this literature review, we could find out tendencies of Korean medicine treatments of purpura and vasculitis up to date and some points that may have clinical significance.
Keywords
Purpura; Vasculitis; Korean Medicine; Herbal Medicine; Literature review;
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Times Cited By KSCI : 10  (Citation Analysis)
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1 Lee YU, Kim IR, Choe CW, Lee GN, Lee YS, Gwak JJ, et al. Literature review of purpura. Herb Formula Sci. 2001;9(1):137-63.
2 The Society of Korean Dermatology. Textbook of Dermatology. 6th ed. Seoul:Daehan med. 2015:597-607.
3 Lamadrid-Zertuche AC, Garza-Rodriguez V, Ocampo-Candiani J de J. Pigmented purpura and cutaneous vascular occlusion syndromes. An Bras Dermatol. 2018;93(3):397-404.   DOI
4 Hong SH. A Case of Idiopathic Thrombocytopenic Purpura. Korean J Orient Int Med. 2000;21(4):677-82.
5 Choi IH. A Case of Progressive Pigmented Purpuric Dermatosis. J Korean Med Ophthalmol Otolaryngol Dermatol. 2001;14(2):194-7.
6 Hong SH, Kim SH. A Clinical Case of Dermatomyositis Complicated by Henoch-Schonlein Purpura. J Korean Oriental Med. 2002;23(2):225-30.
7 Chang SH. A Case of Purpura. J Somun Orient Med. 2003;8:30-1.
8 Ko SG, Jung HS. Study on the Chinese medical journal analysis about Hyeal Jeung (血證). J Orient Chr Dis. 1999;5(1):177-201.
9 Chan H, Tang YL, Lv XH, Zhang GF, Wang M, Yang HP, et al. Risk Factors Associated with Renal Involvement in Childhood Henoch-Schonlein Purpura: A Meta-Analysis. PLoS ONE. 2016;11(11):1-21.
10 Counahan R, Winterborn MH, White RHR, Heaton JM, Meadow SR, Bluett NH, et al. Prognosis of Henoch-Schonlein nephritis in children. BMJ. 1977:11-4.
11 Kwon KY. Diagnosis and treatment of purpura. Korean J Med. 2008;75(2):169-72.
12 Ahn HS. Textbook of pediatrics. 10th ed. Seoul: MiraeN. 2012:1186-7.
13 Kim JH, Yoon HJ. Study of two cases for allergic purpura. Korean J Orient Physiol Pathol. 2005;19(3):821-5.
14 Hong EJ, Ha TS. The effect of steroid on renal involvement in Henoch-Shonlein purpura. J Korean Soc Pediatr Nephrol. 2007;11(2):185-94.   DOI
15 The Department of Dermatology of Catholic College of Medicine. Current Principles and Clinical Practice of Dermatology. 1st ed. Seoul:Koonja. 2011:111.
16 Kim JS, Choi JH, Kim JH, Jeong MY, Park SY. A Case of Allergic Pupura treated with Korean Medicine - Two Cases. Herb Formula Sci. 2016;24(1):63-70.   DOI
17 Reamy BV, Williams PM, Lindsay TJ. Henoch-Shonlein Purpura. Am Fam Physician. 2009;80(7):697-704.
18 Kim HS, Kim IH. A Case Study of Taeumin Yangdokbalban Patient diagnosed as Allergic Purpura. J Sasang Const Med. 2003;15(3):139-46.
19 Kim HJ, Kim TY, Lee CW, Kim CH. A Case Report of Progressive Pigmented Purpuric Dermatosis improved with Jibaekjihwang-tang. J Korean Med Ophthalmol Otolaryngol Dermatol. 2013;26(2):109-16.   DOI
20 Kim BNR, Pa가 JM, Chae JW. A Case Report of Allergic Purpura. J Pediatr Korean Med. 2014;28(4):108-17.   DOI
21 Kim NE, Jee SY, Hwangbo M. A Case Report of Polyarteritis Nodosa Treated With Korean Medical Treatment. J Korean Med Ophthalmol Otolaryngol Dermatol. 2018;31(2):143-51.   DOI
22 Moon YJ, Kim CH, Chu HM, Lee JY, Song BK, Won JH. A Case Report of Hypersensitivity Vasculitis Improved by Korean Medecine Treatment. J Int Korean Med. 2018;39(5):964-72.   DOI
23 National Korean Medicine University Textbook Editing Board. Herbology. Seoul:Younglimsa. 2011:10-8.
24 Yang YH, Yu HH, Chiang BL. The diagnosis and classification of Henoch-Schonlein purpura: An updated review. Autoimmun Rev. 2014;13(4-5):355-8.   DOI
25 Kim HW, Hur JW. Update on the Classification Criteria for Vasculitis. Korean J Med. 2014;87(4):401.   DOI
26 Chen KR, Carlson J. Clinical Approach to Cutaneous Vasculitis. Am J Clin Dermatol. 2008;9(2):71-92.   DOI
27 Kim JH, Yoon HJ. Study of Two Cases for Allergic Purpura. Korean J Orient Physiol Pathol. 2005;19(3):821-5.
28 Na WK, Kim HH, Park YJ, So KS, Cho YK, Park EJ. A Case Report of Henoch-Schonlein Purpura. J Korean Orient Pediatr. 2003;17(2):75-83.
29 Yang JS, Yeom SR, Yun KH, Lee JH, Yoon JC, Lee JD et al. Case Report of Takayasu's Arteritis. Korean J Orient Physiol Pathol. 2004;18(1):301-5.
30 Kim CH, Yeon KJ, Roh SS. A Clinical Review of Henoch-Schonlein Purpura - Two Cases. J Korean Med Ophthalmol Otolaryngol Dermatol. 2005;18(3):127-34.
31 Han DH. Clinical Analysis on 106 Cases of Henoch-Schonlein Purpura. Korean J Orient Int Med. 2007;28(3):570-85.
32 No HS, Kim JB. Case Report of Oriental Medicine Treatment of Idiopathic Thrombocytopenic Purpura. Korean J Orient Physiol Pathol. 2007;21(5):1303-6.
33 Jo JK, Kim HY, An CG, Yun CS, Choi EH, Park MC. Two Case Report of Allergic Purpura. J Korean Med Ophthalmol Otolaryngol Dermatol. 2007;20(3):260-7.
34 Lee ES, Kam CW, Youn HM, Jang KJ, Song CH, Kim YK et al. Case Report of Polyarteritis Nodosa Treated with Oriental Treatments Including Acupotomy. J Acupuct Res. 2012;29(3):129-37.
35 Lee JH, Yu SA, Lee SY. A Case Report of Allergic Purpura. J Korean Orient Pediatr. 2012;26(3):12-9.   DOI
36 Suk YH, Min SY, Kim JH. A Literature Study Based on Traditional Chinese Medical Journal about Treatment of Allergic Purpura-Based on Traditional Chinese Medical Journal-. J Pediatr Korean Med. 2013;27(4):77-86.   DOI
37 Gardner Medwin JM, Dolezalova P, Cummins C, Southwood TR. Incidence of Henoch-Schonlein purpura, Kawasaki disease and rare vasculitis in children of different ethnic origins. Lancet. 2002;360(9341):1197-202.   DOI
38 The National College of Korean Medicine Textbook Compilation Committee. Text of Traditional Korean Dermatology & Surgery. Pusan:Sunwoo Publishing. 2007:463-6.