• Title/Summary/Keyword: Kimcheon

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Lsolation of Diterpene acid from Anisotome Lyallii

  • Lim Jin A;Choi Young;Oh In Kio;Kim Hyung Min;Kim Young Ok;Perry Nigel B;Baek Seung Hwa
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.4
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    • pp.1112-1115
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    • 2003
  • The diterpene acid 1 was isolated from the roots of Anisotome lyallii(Apiaceae/Umbelliferae). The structure of the compound was elucidated as anisotomenoic acid 1 on the basis of spectroscopic methods. This compound was evaluated against P388 murine leukaemia and B 16/F10 melanoma cells.

Cytotoxic and antimicrobial deterpene from Anisotome Iyallii

  • Choi, Eun-Young;Yang, Hyun-Ok;Choi, Won-Hyung;Lee, Jeong-Ho;Perry-NigelB;Baek, Seung-Hwa
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.392.2-392.2
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    • 2002
  • Cytotoxic activity against the P388 cell line was seen in a crude extract of Anisotome lyallii. A bioactivity guided isolation led to the isolation of a deterpene. which displayed strong Cytotoxic activity against the P388 cell line (IC50 2.3 $\mu$g/ml), as well as antimicrobial activity against Bacillus subtilis. The structure of de terpene 1 was elucidated by spectroscopic methods. (omitted)

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Analysis of Q Values on the Crust of the Kimcheon and Mokpo Regions, South Korea (남한 김천.목포 일대 지각의 Q 값 분석)

  • Do, Ji-Young;Lee, Yoon-Joong;Kyung, Jai-Bok
    • Journal of the Korean earth science society
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    • v.27 no.4
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    • pp.475-485
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    • 2006
  • The physical properties of the central and southwestern crust of South Korea were estimated by comparing values of ${Q_P}^{-1}\;and\;{Q_S}^{-1}$ in the Kimcheon and Mokpo areas. In order to get ${Q_P}^{-1}\;and\;{Q_S}^{-1}$ values, seismic data were collected from two stations of the KIGAM network (KMC and MUN) and four stations of the KMA network (CPN, KUC, MOP, and WAN). An extended coda-normalization method was applied to these data. Estimates of ${Q_P}^{-1}\;and\;{Q_S}^{-1}$ show variations depending on frequency. As frequencies vary from 3 Hz to 24 Hz, the estimates decrease from $(1.4{\pm}3.9){\times}10^{-3}\;to\;(2.3{\pm}3.5){\times}10^{-4}\;for\;{Q_P}^{-1}\;and\;(1.8{\pm}1.3){\times}10^{-3}\;to\;(1.9{\pm}1.5){\times}10^{-4}\;for\;{Q_S}^{-1}$ in central South Korea, and $(5.9{\pm}4.8){\times}10^{-3}\;to\;(2.2{\pm}3.8){\times}10^{-4}\;for\;{Q_P}^{-1}\;and\;(0.5{\pm}2.8){\times}10^{-3}\;to\;(1.8{\pm}1.6){\times}10^{-4}\;for\;{Q_S}^{-1}$ in southwestern South Korea. According that a frequency-dependent power law is applied to the data, the best fits of ${Q_P}^{-1}\;and\;{Q_S}^{-1}\;are\;0.003f^{-0.49}\;and\;0.005f^{-1.03}$ in central South Korea, and $0.026f^{-1.47}$ and $0.001f^{-0.49}$ in southwestern South Korea, respectively. These values almost correspond to those of seismically stable regions although ${Q_P}^{-1}$ values of southwestern South Korea are a little high due to lack of data used.

Screening of Cytotoxicity and Antimicrobial Effects of Extracts from Atractylodes macrocephala Koidz (백출 추출물의 세포독성과 항균효과검색)

  • Choi Eun Young;Oh Hyun Ju;Park Nang Kyu;Chun Hyun Ja;Ahn Jong Woog;Jeon Byung Hun;Han Du Seok;Lee Hyun Ok;Baek Seung Hwa
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.2
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    • pp.348-352
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    • 2002
  • This study was carried out to evaluate cytotoxic effects of Atractylodes macrocephala Koidz. (A. macrocephala Koidz.) extract on NIH 3T3 fibloblast. SK-MEL-3 (HBT 69) and KB (ATCC No, OCL 17) cell lines. Disruptions in cell organelles were determined by 3-(4,5-dimethylthiazol-2-y1)-2,5-diphenyl-2H-tetrazoliumbromide (MTT) assay. 10.2 mg/ml Concentration of A. macrocephala Koidz. extracts in SK-MEL-3 showed that their susceptibility (sensitivity) to these compounds decreased in the following order ; adriamycin > H₂O > ethyl acetate > ethyl alcohol > chloroform > n-hexane in SK-MEL-3 cell lines ; 5-FU > H₂O > n-hexane > ethyl acetate > ethyl alcohol > chloroform in KB cell lines. In order to develop an antimicrobial agent, A. macrocephala Koidz. was extracted with solvents. The minimal inhibitory concentrations (MICs) of each solvent extract of A. macrocephala Koidz. against microogranisms were also examined. Antimicrobial activities of ampicillin and ketoconazole as references were compared to those of each solvent extract of A. macrocephala Koidz. The antimicrobial activity of the ethyl acetate soluble extract of A. macrocephala Koidz. had growth inhibition activity against S. mutans and P. putida (MICs. 500 ㎍/ml). These results suggest that the ethyl acetate soluble extract of A. macrocephala Koidz. possessed antitumorous and antimicrobial agents

High Power-Factor Single-Stage Half-Bridge High Frequency Resonant Inver (고역률을 가지는 Single-Stage Half-Bridge 고주파 공진 인버터)

  • Won, Jae-Sun;Kim, Dong-Hee;Seo, Cheol-Sik;Cho, Gyu-Pan;Oh, Seung-Hoon;Jung, Do-Young;Bae, Yeong-Ho
    • Proceedings of the KIEE Conference
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    • 2002.07b
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    • pp.1196-1198
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    • 2002
  • A novel single-stage half-bridge high frequency resonant inverter using ZVS(Zero Voltage Switching) with high input power factor suitable for induction heating applications is presented in this paper. The proposed high frequency resonant inverter integrates half-bridge boost rectifier as power factor corrector(PFC) and half-bridge resonant inverter into a single stage. The input stage of the half-bridge boost rectifier is working in discontinuous conduction mode (DCM) with constant duty cycle and variable switching frequency. So that a high power factor is achieved naturally. Simulation results through the Pspice have demonstrated the feasibility of the proposed inverter. This proposed inverter will be able to be practically used as a power supply in various fields as induction heating applications, DC-DC converter etc.

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Effects of a Robot Pet-assisted Program for Elderly People with Dementia (치매노인에 대한 동물로봇 매개 중재 프로그램의 효과)

  • Song, Jung-Hee
    • Journal of Korean Academy of Nursing
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    • v.39 no.4
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    • pp.562-573
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    • 2009
  • Purpose: The purpose of this study was to identify the effects on the cognitive function, Activities of Daily Living (ADL), mood, social behaviors, and problematic behaviors of robot pet-assisted program for elderly people with dementia. Methods: This study was a nonequivalent control group pretest-posttest design. The participants were 32 elders with dementia. Seventeen were assigned to the experimental group and 15 to the control group. The intervention was conducted twicea week for 6 weeks. Results: 1) After the program, cognitive function, ADL, and social behaviors did not show significant differences. 2) After the program, mood of experimental group was significantly better than that of the control group. 3) After the program, problematic behaviors of the experimental group were significantly more diminished than those of control group. 4) As a result of analyzing the response, robot pet-assisted program was effective such as inducing a positive emotional state and increasing communication and interaction. Conclusion: The robot pet-assisted program was effective in changing the mood and diminishing problematic behaviors and had positive effects such as increasing communication and interaction for elders with dementia. Therefore, this program should be considered as a positive program for physical and emotional support for elders with dementia.

Performance Evaluation and Design of Zoom Lens Systems (Zoom Lens계의 성능 평가 및 설계)

  • Ji, Taek Sang
    • Journal of Korean Ophthalmic Optics Society
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    • v.7 no.2
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    • pp.113-121
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    • 2002
  • Nowadays, developed camera, camcorder, CCTV and copier system accept a wide angle and a telephoto lens, and have an excellent capacity. Also, it is small as using aspheric surface. In this paper, after we evaluate and analyze two-group zoom lens system and three-group zoom lens system for camera, we refer to it, and design three-group zoom lens system for camera. Therefore, when we design a zoom lens system for camera, we use a symmetrical system. As using an aspheric surface, we can try to a miniaturization and an efficient improvement. We use optical valuable measure methods, a ray intercept plot, MTF and Seidel coefficient. So, we can confirm to have a similar level to compare with reference model.

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Effects of Tai Chi Exercise in Elderly with Knee Osteoarthritis (슬골관절염 노인환자의 타이치운동 효과)

  • Lee, Hea-Young;Lee, Keum-Jae
    • Journal of Korean Academy of Nursing
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    • v.38 no.1
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    • pp.11-18
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    • 2008
  • Purpose: This study was to determine whether the Sun-style 24 forms of Tai Chi exercise improve pain, stiffness, disability, knee joint motion, mobility, balance or falling. Method: Forty-six community-dwelling elderly subjects (mean age, $75.46{\pm}6.28$) voluntarily participated in an intervention group of either 24 forms of Sun-style T ai Chi for 60 min, 2 times per week for 12 weeks or a control group. A non-equivalent pretest-posttest design was used. Independent t-test and ANCOVA were used to examine group differences by using SPSS12.0. Result: The experimental group had significantly less pain (F=7.60, p=.008) and stiffness (t=-3.19, p=.003) than the control group. Also there were significant improvements in knee joint motion on the right knee (t=2.44, p=.019), left knee (t=2.30, p=.026), rising time (F=8.03, p=.07), balance on the left single leg test (t=2.20, p=.033), and fear of falling (t=-2.33, p=.024) in the Tai Chi exercise group. No significant group differences were found in disability and falls efficacy. Conclusion: The Sun-style 24 forms Tai Chi exercise is effective in decreasing pain, stiffness, fear of falling and it improves balance, rising time, and knee joint motion. We suggest a continuing long term intervention to decrease disability and increase efficacy concerning falls.

Effect of Postpartum Breast-feeding Support by Nurse on the Breast-feeding Prevalence (간호사의 모유 수유 지지가 모유 수유 실천에 미치는 효과)

  • Jang, Gun-Ja;Kim, Sun-Hee;Jeong, Kyung-Soon
    • Journal of Korean Academy of Nursing
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    • v.38 no.1
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    • pp.172-179
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    • 2008
  • Purpose: The purpose of this study was to investigate the effects of the professional nurse's postpartum breast-feeding support on breast-feeding prevalence for mothers who delivered in Baby-Friendly Hospitals (BFH). Methods: This quasi experimental study was designed with a nonequivalent control group post test. The subjects of this study were 55 mothers who were hospitalized in the delivery room of a university hospital which was selected as a BFH in Daegu from October 1, 2005 to June 30, 2006. Twenty nine mothers were assigned to the experimental group and 26 mothers to the control group. Postpartum breast-feeding support by nurses' telephone calls to the experimental group was provided once a week for 4 weeks postpartum and then once a month for 16 weeks postpartum. Four post tests were given at postpartum week 8, 12, and 16. The control group was given a telephone call at postpartum week 4, 8, 12, and 16. Results: The breast-feeding prevalence of the experimental group was significantly higher than that of the control group for each period. Conclusion: Postpartum breast-feeding support by nurses may be a useful intervention to increase breast-feeding prevalence.

The Effects of Weight Control Program on Body Composition, Blood Pressure, Serum Lipid and Self-Regulation Behavior in Obese College Women (비만중재프로그램이 비만 여대생의 신체구성, 혈압, 혈중지질 및 자기조절행위에 미치는 효과)

  • Kim, Kyung Hae;Chung, Bok Yae;Byun, Hye Sun
    • Korean Journal of Adult Nursing
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    • v.19 no.3
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    • pp.339-352
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    • 2007
  • Purpose: The purpose of this study was to investigate the effect of weight control program on body composition(body mass index and waist-hip ratio), blood pressure, serum lipids(total cholesterol, triglyceride, high density lipoprotein and low density lipoprotein) and self-regulation behavior in obese college women. Methods: Forty seven obese subjects were divided into experimental(22) and control(25) groups. The weight control program lasting 12 weeks consisted of a traffic-light diet, jumping-rope exercises, and behavior modification methods with e-mail counseling. The data were collected from 29 March to 17 September of 2004. The variables were assessed before and after intervention for 12 weeks in two groups. Then, those were repeated after a 12 week suspension of intervention in the experimental group. The data were analysed by the SPSS computer program. Results: BMI, HDL, LDL and self-regulation behavior levels showed significant differences between the experimental and control groups. While there were no significant differences in waist-hip ratio, blood pressure, total cholesterol and triglyceride. Conclusion: The weight control program had a positive effect on obese college women, and can be used to control obesity.

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