Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Cytotoxic and antimicrobial deterpene from Anisotome Iyallii

  • Choi, Eun-Young (Dept. of Beauty and Skin Care. Kimcheon Science CollegeDept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Yang, Hyun-Ok (Dept. of Cosmetics. Wonkwang Health Science Colleg) ;
  • Choi, Won-Hyung (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, Jeong-Ho (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Perry-NigelB (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Baek, Seung-Hwa (Dept. of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • Published : 2002.10.01
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Abstract

Cytotoxic activity against the P388 cell line was seen in a crude extract of Anisotome lyallii. A bioactivity guided isolation led to the isolation of a deterpene. which displayed strong Cytotoxic activity against the P388 cell line (IC50 2.3 $\mu$g/ml), as well as antimicrobial activity against Bacillus subtilis. The structure of de terpene 1 was elucidated by spectroscopic methods. (omitted)

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