• 한국임상수의학회지
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• 제14권1호
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• pp.19-23
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• 1997

Ultrasonographic diagnosis of kidney and urinary bladder disease was performed in native Korea cattle. Ultrasonogaphic appearence of kidney and urinaryy baldder according to the growth were determined from 6 to 13 months by monthly examinations in 9 native Korean cattle. The kidney and urinary bladder were examined in standing position. The position, dimension, and structure of both kidneys were determined at 12 intercostal space and paralumbar fossa by use of ultrasonography. Ultrasonograms were obtained with 3.5 or 5.0-MHz sector transducer. The width and depth of the kidney, and the diameter of renal parenchyma and renal sinus were observed. Both kidneys were observedfrom the body surface until 8 months old age, but over the 9 months old age, only right kidney was easily accessible. The width of right kidney at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 5.7, 6.3, 6.9, 7.6, 8.4, 9.3, 9.8 and 10.7 cm, respectively. The depth 5.8, 6.1 and 6.6 cm, respectively. The size of left kidney was similar to right kidney until 8 months old age. After the 9 months old age, only right kidney was easily accessible. The circumference of urinary bladder at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 19.1, 21.7, 22.5, 23.0, 24.2, 25.3, 27.8 and 29.1 cm, respectively. Calculi in urinary bladder were observed by ultrasonography.

• 셀메드
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• 제10권3호
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• pp.19.1-19.6
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• 2020

The kidneys are exposed to toxicants and waste product and can be affected easily by these toxicants and by products of the metabolism. The consumption of adequate water is necessary to remove waste and to keep kidney healthy. Deficiency of liquid in the blood leads to various adverse effects on the kidney. The most common adverse deficiency of liquid in blood is deposition of solid matter in the kidney and subsequently formation of kidney stone. Nephrolithiasis (kidney stone) can be treated by drugs if it is small in size but if it blocks the route due to its big size then surgery is the only way to remove it. The recurrence rate of the problem is very high and it may reappear within 10 years. In Unani literature Hasāh wa Raml al-Kulya (nephrolithiasis) is described in detail. As per Unani literature stagnation of Ghalīz mādda (filthy and viscous matter) in the kidney is the main cause of the formation of kidney stone. Various single and compound formulations drugs are described for the management of kidney stone which are very effective as well as safe. Management is divided into two parts i.e. symptomatic treatment to relieve pain and to methods adopted to remove stone from the kidney. Musakkin-i-Waja'(analgesic) drugs are used for pain while Mufattit-i-Hasāh (lithotriptic) and Mudirr-i-Bawl (Diuretic) drugs are used to remove stone. Majoon Aqrab, Qurs Kaknaj and Dawa-e-Gurda etc. are compound drugs mentioned in literature for removal of kidney stone. Single drugs like Alu Balu, Tukhm Khayar, and Kharkhask etc. are also used for same purpose.

• 한국통신학회논문지
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• 제34권10B호
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• pp.1062-1069
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• 2009

비만으로 인해 대사증후군을 많이 앓고 있는 상황에서 후유증으로 신장 질환이 커다란 사회문제가 되고 있는 실정이다. 따라서 자각증상이 없는 신장의 이상 유무를 조기에 판단하여 적절한 조치를 취하는 것이 무엇보다 중요하다. 이를 위해 본 논문에서는 음성 분석을 통해 신장 질환을 무자각, 무구속, 무통종의 방법으로 진단할 수 있는 방법을 제안하였다. 구성하고자 하는 전체 시스템은 크게 음성 분석과 얼굴색을 살피는 방법을 결합시키는 시스템이 개발되고 있으며 이 중 본 논문은 입술소리를 기반으로 신장 질환을 진단하는 방법에 설계하였다. 이를 위해 본 논문에서는 첫째, 신장 질환을 앓고 있는 환자와 정상인을 대상으로 피실험자 집단을 각각 구성하고 입술소리의 수치학적 분석을 실험으로 출력하고 그 결과값에 대한 비교 분석을 수행하였으며 둘째, 한의학적 청진 이론과 언어학, 음성학과의 상관성을 분석하고 이를 기반으로 음성에 대한 신장의 특징 요소를 추출하여 제1포먼트 주파수와의 연관성을 도출하였다. 실험 결과 신장 질환자 집단이 정상인 집단보다 제1포먼트 주파수 대역폭이 넓게 형성되는 결과를 추출하였으며 최종적으로 입술소리만으로 신장 질환을 진단할 때의 오진 확률에 대해 계산하였다.

• Child Health Nursing Research
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• 제9권1호
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• pp.28-35
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• 2003

Purpose: The purpose of this study is to investigate correlations in vital sign changes, the severity of pain, signs of complications, and the duration of sandbag management in order to suggest a standardized practice related to sandbag management in children with Nephrotic Syndrome(NS). Method: From October 2000 to May 2001, seventy children with NS who underwent kidney biopsy were interviewed at one hospital in Seoul Korea, and participated in this study. Result: 1) The average sandbag applying time after kidney biopsy was 18.1 hours. 2) Systolic blood pressure and respiration increased until 15 minutes after kidney biopsy, after then, they decreased signifi- cantly (systolic BP, p= .006; respiration, p= .029). However, no significant changes were noted in diastolic blood pressure and pulse. 3) Pain was reported minimal for 1 hour after kidney biopsy. The severity of pain increased until 12 hours after the procedure, then, decreased significantly(p= .0001). 4) Reported complications were hematuria (74.7％) and abnormal sonogram (32.9％). No apparent bleeding on the biopsy region was reported in any children. Conclusion: From these findings, it is possible to change the protocols of the duration of absolute bed rest time and sandbag application management shortly after kidney biopsy. But it is needed to study the fit protocols for kidney biopsy. Several implications in nursing practice are suggested. 1) Replicated studies for more participants are needed. 2) Further research on the effect of sandbag application after kidney biopsy is required. 3) The best duration of sandbag application management after kidney biopsy need to be investigated.

• 대한한방소아과학회지
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• 제37권4호
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• pp.1-14
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• 2023

Objectives This study aimed to evaluate the correlation between pediatric weakness scale scores and growth indices. Furthermore, we intended to calculate the cut-off values for diagnosing Kidney Weak Children through growth indices. Methods A total of 193 patients, aged 6 - 12 years, underwent both the pediatric weakness scale and bone age assessment, and the correlations between the pediatric weakness scale and growth indices were analyzed. Moreover, the cut-off values for diagnosing Kidney Weak Children were calculated. Differences in bone age and predicted height between the normal group and Kidney Weak Children, classified according to the calculated cut-off values, were analyzed. Results The weakness of the Shin or kidney system was significantly correlated with the height percentile, weight percentile, differences in current height percentile and mid parental height percentile, differences in predicted height and mid parental height, and differences in bone age and chronological age. When the criteria for diagnosing Kidney Weak Children is set at "height percentile of ≤25% and weight percentile of ≤25%", the sensitivity and specificity of the cut-off value were maximized. The cut-off values for weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years. Conclusions To diagnose Kidney Weak Children, the cut-off values of weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제49권5호
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• pp.243-251
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• 2023

Objectives: Although a few studies have investigated the relationship between kidney and oral function (number of remaining teeth), their results remain inconclusive. Therefore, this study aimed to investigate the relationship between kidney function and oral health in community-dwelling healthy elderlies and examine the factors associated with kidney function. Materials and Methods: We used cross-sectional data from the Shimane prefecture cohort recruited by the Center for Community-Based Health Research and Education in 2019. We collected clinical data on dental status, background factors and kidney function (estimated glomerular filtration rate [eGFR], mL/min/1.73 m² and creatinine levels, mg/dL). Results: The study enrolled 481 participants, whose mean age was 66.7±7.4 years, and 223 (46.4%) participants were men. Multivariate analysis revealed significant correlations between eGFR (B=0.17, P=0.04), creatinine (B=-0.54, P<0.01), and the number of remaining teeth. The number of remaining teeth was associated with creatinine and eGFR, which are indicators of kidney function. Conclusion: This study suggests that preserving the teeth may prevent decline in kidney function. Dental professionals should provide instructions and professional care to reduce the risk of systemic diseases such as kidney dysfunction.

• IMMUNE NETWORK
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• 제23권2호
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• pp.15.1-15.17
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• 2023

Innate lymphoid cells (ILCs) are critical immune-response mediators. Although they largely reside in mucosal tissues, the kidney also bears substantial numbers. Nevertheless, kidney ILC biology is poorly understood. BALB/c and C57BL/6 mice are known to display type-2 and type-1 skewed immune responses, respectively, but it is unclear whether this extends to ILCs. We show here that indeed, BALB/c mice have higher total ILCs in the kidney than C57BL/6 mice. This difference was particularly pronounced for ILC2s. We then showed that three factors contributed to the higher ILC2s in the BALB/c kidney. First, BALB/c mice demonstrated higher numbers of ILC precursors in the bone marrow. Second, transcriptome analysis showed that compared to C57BL/6 kidneys, the BALB/c kidneys associated with significantly higher IL-2 responses. Quantitative RT-PCR also showed that compared to C57BL/6 kidneys, the BALB/c kidneys expressed higher levels of IL-2 and other cytokines known to promote ILC2 proliferation and/or survival (IL-7, IL-33, and thymic stromal lymphopoietin). Third, the BALB/c kidney ILC2s may be more sensitive to the environmental signals than C57BL/6 kidney ILC2s since they expressed their transcription factor GATA3 and the IL-2, IL-7, and IL-25 receptors at higher levels. Indeed, they also demonstrated greater responsiveness to IL-2 than C57BL/6 kidney ILC2s, as shown by their greater STAT5 phosphorylation levels after culture with IL-2. Thus, this study demonstrates previously unknown properties of kidney ILC2s. It also shows the impact of mouse strain background on ILC2 behavior, which should be considered when conducting research on immune diseases with experimental mouse models.

• 대한방사선기술학회지:방사선기술과학
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• 제32권2호
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• pp.153-160
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• 2009

소아 요로 감염의 초음파 검사 유용성검토에 대한 연구결과 다음과 같은 결론을 얻었다. 1. 요로 감염으로 진단된 환 아 122명 중 1세 미만이 100명으로 82%였고 남여 성비는 1.7 : 1로 남아가 높았으며 122명 중 신장초음파 검사(Kidney sonography), 배뇨성방광요도조영술(Voiding cystourethrography), 신주사검사($^{99m}TC$ DMSA-scan), 3가지 영상의학적 검사를 시행한 환 아는 77명이였으며, 3가지 영상의학적검사중 진단율은 신장초음파검사(Kidney Sonography) 51%, 신주사 검사($^{99m}TC$ DMSA-scan) 42% 배뇨성방광요도 조영술 (VCUG) 22%의 순으로 나타났다. 2. 신장초음파검사기술(Kidney Sonography)과 배뇨성 방광요도 조영술(VCUG)의 상관관계 비교에서 민감도 (sensitivity) 82% 특이도(specificity)는 58%였으며, 신장초음파검사(Kidney Sonography)와 신주사검사 $^{99m}TC$(DMSA-scan) 상관관계 비교에서는 민감도(sensitivity) 66%, 특이도(specificity)는 67%로 나타났다. 3. 소아 요로 감염 검사에서 환 아의 고통과 불쾌감, 수치심, 정신적인 스트레스유발, 검사 후 조영제에 대한 부작용, 방사선 피폭 등 검사와 관련된 합병증을 고려할 때 신장초음파검사(Kidney Sonography)의 유용성이 가장 높은 것으로 나타났다.

• 한국해양바이오학회지
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• 제13권2호
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• pp.86-93
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• 2021

A high salt diet contributes to kidney damage by causing hypoxia and oxidative stress. Recently, an increase in dietary salt has been reported to induce an inflammatory phenotype in immune cells, further contributing to kidney damage. However, studies on the exact mechanism and role of a high salt diet on the inflammatory response in the kidneys are still insufficient. In this study, a cisplatin-induced acute kidney injury model using C57BL/6 mice was used to analyze the effect of salt intake on kidney injury. Results showed that high salt administration aggravated kidney edema in mice induced by treatment with cisplatin. Moreover, the indicators of kidney and liver function impairment were significantly increased in the group cotreated with high salt compared with that treated with cisplatin alone. Furthermore, the exacerbation of kidney damage by high salt administration was also associated with a decrease in the number of cells in the immune regulatory system. Additionally, high salt administration further decreased renal perfusion functions along with increased cisplatin-induced damage to proximal tubules. This was accompanied by increased expression of T cell immunoglobulin, mucin domain 1 (a biomarker of kidney injury), and Bax (a pro-apoptotic factor). Moreover, cisplatin-induced expression of proinflammatory mediators and cytokines, including cyclooxygenase-2 and tumor necrosis factor-α in kidney tissue, was further increased by high salt intake. Therefore, these results indicate that the kidney's inflammatory response by high salt treatment can further promote kidney damage caused by various pathological factors.

• 한국콘텐츠학회논문지
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• 제22권9호
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• pp.561-569
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• 2022

우리나라 신장암 발생을 소득 수준에 따라 확인하고 병기별로 분석하여 소득 수준에 따른 지연된 진단 정도의 차이를 확인하기 위하여 2015년부터 2017년까지 중앙암등록자료 및 국민건강보험공단, 건강보험심사평가원 데이터베이스를 연계하여 국가 단위 신장암 코호트를 구축하여 병기별, 소득수준별 신장암 발생률을 산출하였다. 연구 기간 중 우리나라 신장암 발생률은 모든 소득 분위에서 증가하나 의료보장인구에서만 감소하는 양상을 보였다. 신장암 발생률은 인구 10만 명 당 7.35 명이었고 이 중 83.54%가 국한 및 국소 신장암으로 소득 상위 20%에서 인구 10만 명 당 21.46명의 높은 발생률을 보였다. 그 중 국한 및 국소 신장암이 18.37명으로 소득 수준이 높을수록 국한 및 국소 신장암 발생률이 높은 것으로 확인된 반면 소득 수준이 낮을수록 원격 전이된 상태로 신장암을 진단받을 위험이 높음(소득 하위 20% adj.OR 1.807, 95% CI 1.411-2.222)을 확인하였고 의료보장인구에서는 병기 미상으로 진단받을 위험비가 1.926(95% CI 1.317, 2.816)으로 관찰되었다. 소득 수준이 높을수록 조기에 암을 진단하는 빈도가 높지만 소득 수준이 낮을수록 전이 신장암으로 진단받거나 병기 미상으로 진단받을 위험이 높아 소득 수준에 따른 건강 불평등이 관찰되었다.