• 제목/요약/키워드: Kaplan-Meier Method

검색결과 320건 처리시간 0.028초

THE EMPIRICAL LIL FOR THE KAPLAN-MEIER INTEGRAL PROCESS

  • Bae, Jong-Sig;Kim, Sung-Yeun
    • 대한수학회보
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    • 제40권2호
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    • pp.269-279
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    • 2003
  • We prove an empirical LIL for the Kaplan-Meier integral process constructed from the random censorship model under bracketing entropy and mild assumptions due to censoring effects. The main method in deriving the empirical LIL is to use a weak convergence result of the sequential Kaplan-Meier integral process whose proofs appear in Bae and Kim [2]. Using the result of weak convergence, we translate the problem of the Kaplan Meier integral process into that of a Gaussian process. Finally we derive the result using an empirical LIL for the Gaussian process of Pisier [6] via a method adapted from Ossiander [5]. The result of this paper extends the empirical LIL for IID random variables to that of a random censorship model.

경쟁적 위험하에서의 신뢰성 분석 (Reliability Analysis under the Competing Risks)

  • 백재욱
    • 한국신뢰성학회지:신뢰성응용연구
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    • 제16권1호
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    • pp.56-63
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    • 2016
  • Purpose: The purpose of this study is to point out that the Kaplan-Meier method is not valid to calculate the survival probability or failure probability (risk) in the presence of competing risks and to introduce more valid method of cumulative incidence function. Methods: Survival analysis methods have been widely used in biostatistics division. However the same methods have not been utilized in reliability division. Especially competing risks cases, where several causes of failure occur and the occurrence of one event precludes the occurrence of the other events, are scattered in reliability field. But they are not noticed in the realm of reliability expertism or they are analysed in the wrong way. Specifically Kaplan-Meier method which assumes that the censoring times and failure times are independent is used to calculate the probability of failure in the presence of competing risks, thereby overestimating the real probability of failure. Hence, cumulative incidence function is introduced and sample competing risks data are analysed using cumulative incidence function and some graphs. Finally comparison of cumulative incidence functions and regression type analysis are mentioned briefly. Results: Cumulative incidence function is used to calculate the survival probability or failure probability (risk) in the presence of competing risks and some useful graphs depicting the failure trend over the lifetime are introduced. Conclusion: This paper shows that Kaplan-Meier method is not appropriate for the evaluation of survival or failure over the course of lifetime. In stead, cumulative incidence function is shown to be useful. Some graphs using the cumulative incidence functions are also shown to be informative.

단조 서포트벡터기계를 이용한 카플란-마이어 생존함수의 평활 (Smoothing Kaplan-Meier estimate using monotone support vector regression)

  • 황창하;심주용
    • Journal of the Korean Data and Information Science Society
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    • 제23권6호
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    • pp.1045-1054
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    • 2012
  • 서포트벡터 기계는 분류 및 비선형 함수추정에서 유용하게 사용되고 있는 통계적 기법이다. 본 논문에서는 두 개의 입력변수와 회귀함수의 단조 관계를 이용하여 단조 서포트벡터기계를 제안하고, Kaplan-Meier의 방법에 의해서 생존함수의 추정값이 주어진 경우 제안된 방법을 이용하여 생존 함수를 평활하는 방법 또한 제안한다. 모의실험에서는 실제 생존함수를 이용하여 Kaplan-Meier의 방법에 의한 생존함수의 추정값과의 성능을 비교함으로써 제안된 방법의 우수성을 보이기로 한다.

Comparison of the Kaplan-Meier and Nelson Estimators using Bootstrap Confidence Intervals

  • Cha, Young Joon;Lee, Jae Man
    • 품질경영학회지
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    • 제23권4호
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    • pp.42-51
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    • 1995
  • The bootstrap confidence intervals are a computer-based method for assigning measures of accuracy to statistical estimators. In this paper we examine the small sample behavior of the Kaplan-Meier and Nelson-type estimators for the survival function using the bootstrap and asymptotic normal-theory confidence intervals. The Nelson-type estimator is nearly always better than the Kaplan-Meier estimator in the sense of achieved error rates. From the point of confidence length, the reverse is true. Also, we show that the bootstrap confidence intervals are better than the asymptotic normal-theory confidence intervals in terms of achieved error rates and confidence length.

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전이성 폐암에 대한 외과적 치험 (Surgical treatment of Metastatic Lung Cancer)

  • 이종호;임용택;신용철;정승혁;김병열
    • Journal of Chest Surgery
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    • 제32권1호
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    • pp.27-31
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    • 1999
  • 배경: 최근 항암화학요법의 발달에도 불구하고 전이성폐암에 대한 예후는 불량하다. 이에비해 전이성폐암에 대한 외과적 요법후 좋은 결과를 보이는 보고가 증가하고 있다. 그래서 전이성 폐암에 대한 치료에 도움이 되고자 본원의 경우를 관찰하였다. 대상 및 방법: 1983년부터 1997년까지 수술적 치료를 했던 17례를 분석하였고 Kaplan-Meier 방법으로 5년생존률을 구하였다. 결과: 평균연령은 42.8세였고 남녀비는 10:7이었다. 수술은 단일폐엽절제술이 8례, 전폐적출술이 3례, 부분절제술이 1례, 쌍폐엽절제술이 1례, 폐엽절제술 및 부분절제가 3례있었다. 술후 5명이 사망하였고 이중 재발로 인한 것은 3례였다. 나머지 12례의 환자들중 3명은 재발하여 현재 외래추적관찰중이며 9명은 재발없이 건강한 상태로 외래추적 관찰중에 있다. 술후 평균 생존기간은 40.5개월이었다. Kaplan-Meier 방법으로 구한 5년생존율은 60.4%였다. 결론: 앞으로 더많은 경험이 필요하지만 전이성폐암에 대해서 더 적극적인 수술적치료를 하는 것이 필요하다고 생각한다.

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Regression Quantiles Under Censoring and Truncation

  • Park, Jin-Ho;Kim, Jin-Mi
    • Communications for Statistical Applications and Methods
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    • 제12권3호
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    • pp.807-818
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    • 2005
  • In this paper we propose an estimation method for regression quantiles with left-truncated and right-censored data. The estimation procedure is based on the weight determined by the Kaplan-Meier estimate of the distribution of the response. We show how the proposed regression quantile estimators perform through analyses of Stanford heart transplant data and AIDS incubation data. We also investigate the effect of censoring on regression quantiles through simulation study.

Conditional Bootstrap Methods for Censored Survival Data

  • Kim, Ji-Hyun
    • Journal of the Korean Statistical Society
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    • 제24권1호
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    • pp.197-218
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    • 1995
  • We first consider the random censorship model of survival analysis. Efron (1981) introduced two equivalent bootstrap methods for censored data. We propose a new bootstrap scheme, called Method 3, that acts conditionally on the censoring pattern when making inference about aspects of the unknown life-time distribution F. This article contains (a) a motivation for this refined bootstrap scheme ; (b) a proof that the bootstrapped Kaplan-Meier estimatro fo F formed by Method 3 has the same limiting distribution as the one by Efron's approach ; (c) description of and report on simulation studies assessing the small-sample performance of the Method 3 ; (d) an illustration on some Danish data. We also consider the model in which the survival times are censered by death times due to other caused and also by known fixed constants, and propose an appropriate bootstrap method for that model. This bootstrap method is a readily modified version of the Method 3.

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이종 환경에서 운용되는 부품의 신뢰도 평가 방법 연구 (Study on the Reliability Evaluation Method of Components when Operating in Different Environments)

  • 황정택;김종학;전주연;한재현
    • 한국안전학회지
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    • 제32권5호
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    • pp.115-121
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    • 2017
  • This paper is to introduce the main modeling assumptions and data structures associated with right-censored data to describe the successful methodological ideas for analyzing such a field-failure-data when components operating in different environments. The Kaplan - Meier method is the most popular method used for survival analysis. Together with the log-rank test, it may provide us with an opportunity to estimate survival probabilities and to compare survival between groups. An important advantage of the Kaplan - Meier curve is that the method can take into account some types of censored data, particularly right-censoring. The above non-parametric method was used to verify the equality of parts life used in different environments. After that, we performed the life distribution analysis using the parametric method. We simulated data from three distributions: exponential, normal, and Weibull. This allowed us to compare the results of the estimates to the known true values and to quantify the reliability indices. Here we used the Akaike information criterion to find a suitable life time distribution. If the Akaike information criterion is the smallest, the best model of failure data is presented. In this paper, no-nparametrics and parametrics methods are analyzed using R program which is a popular statistical program.

모 한방병원에 내원한 뇌혈관 질환자들의 예후 (Survival Probability of the Patients with Cerebral Vascular Disease Who Visited an Oriental Hospital)

  • 김지용;서운교
    • 대한한의학회지
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    • 제23권4호
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    • pp.91-97
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    • 2002
  • Objective: This study was conducted to know the survival probability of the patients with cerebrovascular disease. Method: 1,341 patients who were suspected of having cerebrovascular disease clinically were investigated by telephone and NHIC (National Health Insurance Corporation) data. Conclusion: 1. The study population was grouped as 'Negative Brain CT findings' (11.8%), 'Hemorrhage' (12.4%) and 'Infarction' (75.7%). 2. The survival probabilities calculated by the Life Table method were statistically significant among brain CT finding groups (P<0.01). 3. The mean survival time calculated by the Kaplan-Meier method were also statistically significant among brain CT finding groups (P<0.01). 4. The result of Cox regression model was that sex (OR=0.7), age (OR=1.07), diabetes mellitus (OR=1.38), and heart disease (OR=1.69) affected the survival of the patients with cerebrovascular disease.

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기술평가 자료를 이용한 중소기업의 생존율 추정 및 생존요인 분석 (A Study on the Survival Probability and Survival Factors of Small and Medium-sized Enterprises Using Technology Rating Data)

  • 이영찬
    • 지식경영연구
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    • 제11권2호
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    • pp.95-109
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    • 2010
  • The objectives of this study are to identify the survival function (hazard function) of small and medium enterprises by using technology rating data for the companies guaranteed by Korea Technology Finance Corporation (KOTEC), and to figure out the factors that affects their survival. To serve the purposes, this study uses Kaplan-Meier Analysis as a non-parametric method and Cox proportional hazards model as a semi-parametric one. The 17,396 guaranteed companies that assessed from July 1st in 2005 to December 31st in 2009 are selected as samples (16,504 censored data and 829 accident data). The survival time is computed with random censoring (Type III) from July in 2005 as a starting point. The results of the analysis show that Kaplan-Meier Analysis and Cox proportional hazards model are able to readily estimate survival and hazard function and to perform comparative study among group variables such as industry and technology rating level. In particular, Cox proportional hazards model is recognized that it is useful to understand which technology rating items are meaningful to company's survival and how much they affect it. It is considered that these results will provide valuable knowledge for practitioners to find and manage the significant items for survival of the guaranteed companies through future technology rating.

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