• Journal of Korean Medicine for Obesity Research
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• v.19 no.2
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• pp.113-118
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• 2019

A counseling manual for the standardized management of obesity in Korean Medicine was developed. Four specialist for obesity and ten advisors participated in the development. The development process was conducted in order to investigate the needs of clinical doctors for obesity, search for related books and references, determine the contents of the manual, produce the manual, and review of the advisors. The contents of the manual were written in order of goal of obesity counseling, assessment of obesity and health risk factors, assessment of obesity-related lifestyles, counseling for weight management, and counseling for Korean Medical treatment. This manual is the first standardized counseling manual developed, and it is meaningful to provide a counseling method for comprehensive Korean Medicine obesity care. Although there were various limitations in the review of the advisory committee, it is expected that this study will be used as a basic data for the establishment of obesity-related health care policy. We hope that obesity counseling of Korean Medicine will be settled as one of the certified korean medical treatment.

• Food Science of Animal Resources
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• v.35 no.5
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• pp.604-610
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• 2015

We investigated the synergic anti-inflammatory activity of Gleditsia sinensis Lam. (GS) extract and Lactobacillus brevis KY21 both in vitro and in vivo. Western blot analysis and immunostaining showed that AKT phosphorylation that increased by the exposure of LPS were significantly decreased by the presence of either GS extract or L. brevis KY21. In addition, p65 intracellular transport was critically inhibited by GS extract and L. brevis KY21. We further studied these effects using an in vivo dextran sulfate sodium (DSS)-induced mouse model. Body weight, food intake, and clinical scores were dramatically decreased after treatment with DSS, whereas these effects were palliated by the addition of GS extract and L. brevis KY21. Importantly, transcription of genes encoding pro-inflammatory cytokines including IL-1β, TNF-α, and IFN-γ in mesenteric lymph nodes (MLN) and the spleen were increased by DSS treatment, whereas they were inhibited by the presence of GS extract and L. brevis KY21.

• The Korean Journal of Pain
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• v.25 no.1
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• pp.55-59
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• 2012

Lumbar spinal stenosis is a commonly treated with epidural injections of local anesthetics and corticosteroids, however, these therapies may relieve leg pain for weeks to months but do not influence functional status. Furthermore, the majority of patients report no substantial symptom change over the repeated treatment. Utilizing balloon catheters, we successfully treated with three patients who complained persistent symptoms despite repeated conventional steroid injections. Our results suggest that transforaminal decompression using a balloon catheter may have potential in the nonsurgical treatment of spinal stenosis by modifying the underlying pathophysiology.

• Journal of Haehwa Medicine
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• v.26 no.1
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• pp.58-67
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• 2017

Objectives:This study was designed to report treatment by Sasang Constitutional Medicine to the patients with Major Neurocognitive Disorder(Dementia) from various causes. Methods:These two patients were diagnosed as Taeeumin and Soyangin according to the result of Sasang constitutional diagnosis, and treated by Sasang constitutional medications. The progress was evaluated with the Korean version of Mini-Mentel State Exam(KMMSE) and Global Disorientation Scale(GDS). Result:The symptoms like wandering, insomnia, cognitive disorder was improved in these patients. Also, KMMSE and GDS score were highly improved. the one patient was cured with Cheongsimyeonja-tang and and the other was cured with Jihwangbaekho-tang and Yanggyuksanhwa-tang. Conclusion:This cases show that Sasang constitutional herbal medications are an effective treatment for the patients with Major Neurocognitive Disorder.

• Journal of Acupuncture Research
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• v.17 no.3
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• pp.45-56
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• 2000

Objectives : Meridian Scraping Therapy(MST: Kwal-Sa: 刮痧) has not well known in Korea. But it's a kind of Traditional Physical Therapy wide spreaded in China and Taiwan. So I want to introduce this new Therapy by summarizing the basic theories and practical manipulations. Conclusions : To analyse the meaning of the character Kwal-Sa, Kwal(刮) means scraping the skin by some tools and Sa(痧) means originally the red spots on skin of measles but in this therapy it's the red spot on skin after the treatment. Meridian Scraping Therapy is based on the meridiology and holism which are the basic theory of Oriental Medicine. The main effects of Meridian Scraping Therapy are draining of pathogenic factors, promoring the flow of ki and blood, tonify yang, balancing the harmony of intemal organs and enhancing the immuno-ability in body. Rhinoceros corpus is common matrial of MST-plate which is the tool of manipulation. And by this plate several manipulation is performed according to the symptom and the locations of pain. The merits of MST are that easily learned by practician, the effects of the treatment are very quickly manifest and no significant side-effects. And additionally this therapy performed not only for treat diseases but prevent it and preserve health.

• Journal of Navigation and Port Research
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• v.33 no.2
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• pp.161-166
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• 2009

Lactobacillus sp., Acetobacter sp. and yeast were the most dominant organisms in the EM stock culture and subculture product. Lactic acid bacteria and yeast were able to grow in the fermentation process utilizing seawater. EM treatment of higher concentrations using EM stock culture and EM clay balls (1% or 4%) contributed to an early removal of malodor and an increase of DO in the polluted sediments, indicating an odor-removing activity of EM. The EM treatment of higher concentrations (1% or 4%) somewhat appeared to modify the microbial communities within the sediments, which was confirmed by existence of a few unique fragments from the stock culture based on PCR-DGGE. It still remains to be elucidated that EM cultures were directly involved in the malodor removal and potential sediment bioremediation.

• Journal of Sasang Constitutional Medicine
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• v.26 no.4
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• pp.409-421
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• 2014

Objectives The aim of this study was to report a improvement of tension type headache severity after using the Melonis Pedicus. Methods 3 Taeeumin patients, suffering from headache, treated with Melonis Pedicus, herb medicine, and acupuncture. After the treatment, Severity of headache was evaluated by Numerical Rating Scale(NRS). Also we checked the reponse of the Melonis Pedicus, and vital sign. Results & Conclusions After using the Melonis Pedicus, the severity of headache decreased from NRS 8 to NRS 1(case1), from NRS 10 to NRS 7(case 2), and from NRS 8 to NRS 6(case 3). And there was not any adverse effect. In conclusion, this study shows that using Meloni Pedicus can be effective treatment for Taeeumin tension type headache patient.

• Journal of Sasang Constitutional Medicine
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• v.28 no.4
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• pp.381-395
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• 2016

Objectives The aim of this study was to report improvements on the symptoms of Flushing for three soyangin female patients after using sasang constitutional medicines. Methods The patients were diagnosed with Soyangin Symptomatology and treated with Soyangin sasang constitutional medicines. The patient's subjective symptoms of flushing and discomfort in sleeping were observed using the Visual Analogue Scale(VAS) respectively during the treatment period. And the patient's subjective symptoms of the pain were observed using Numerical Rating Scale(NRS). The period of the patient's defecation interval were also observed. Results and Concluions The symptoms of flushing, discomfort in sleeping and the pain improved remarkedly in all respects. In conclusion, this study shows that Sasang Constitutional Medicine can be an effective treatment for Soyangin patient with Flushing.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.1
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• pp.128-137
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• 2015

Objectives: Spontaneous pregnancy is a rare event after repeated failure of in vitro fertilization (IVF) or Intrauterine insemination (IUI) treatment. So this paper is to report the natural pregnancy of Gamiseogagjihwang-tang treatments on two infertile patients who were repeatedly failed in IVF or IUI. Methods: One patient was a 35-year-old patient diagnosed with the adenomyosis and contralateral tubal obstruction, treated with 90 cc Gamiseogagjihwang-tang two times per day for 6 weeks after second failure of IVF. The other patient was a 34-year-old patient undergone induced abortion by three times, treated with 90 cc Gamiseogagjihwang-tang two times per day for 4 weeks after second failure of IUI. Results: Through taking Gamiseogagjihwang-tang without assisted reproduction techniques, two cases got pregnant naturally. Conclusions: These cases suggest that Gamiseogagjihwang-tang is effective in treating infertile female after failure in IVF or IUI and inducing spontaneous pregnancy. Therefore, there needs to be more trial on infertile patients treated with Seogagjihwang-tang.

• Laboraroty Animal Research
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• v.33 no.3
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• pp.244-250
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• 2017

${\alpha}$-Synuclein is abundantly expressed in neuronal tissue, plays an essential role in the pathogenesis of neurodegenerative disorders, and exerts a neuroprotective effect against oxidative stress. Cerebral ischemia causes severe neurological disorders and neuronal dysfunction. In this study, we examined ${\alpha}$-synuclein expression in middle cerebral artery occlusion (MCAO)-induced cerebral ischemic injury and neuronal cells damaged by glutamate treatment. MCAO surgical operation was performed on male Sprague-Dawley rats, and brain samples were isolated 24 hours after MCAO. We confirmed neurological behavior deficit, infarction area, and histopathological changes following MCAO injury. A proteomic approach and Western blot analysis demonstrated a decrease in ${\alpha}$-synuclein in the cerebral cortices after MCAO injury. Moreover, glutamate treatment induced neuronal cell death and decreased ${\alpha}$-synuclein expression in a hippocampal-derived cell line in a dose-dependent manner. It is known that ${\alpha}$-synuclein regulates neuronal survival, and low levels of ${\alpha}$-synuclein expression result in cytotoxicity. Thus, these results suggest that cerebral ischemic injury leads to a reduction in ${\alpha}$-synuclein and consequently causes serious brain damage.