• Title/Summary/Keyword: KINETIC

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Quantitative risk assessment of foodborne Salmonella illness by estimating cooking effect on eggs from retail markets

  • Hyemin Oh;Yohan Yoon;Jang Won Yoon;Se-Wook Oh;Soomin Lee;Heeyoung Lee
    • Journal of Animal Science and Technology
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    • v.65 no.5
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    • pp.1024-1039
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    • 2023
  • In this study, we performed a quantitative microbial risk assessment (QMRA) of Salmonella through intake of egg consumption after cooking (dry-heat, moist-heat, and raw consumption). Egg samples (n = 201) from retail markets were analyzed for the presence of Salmonella. In addition, temperature and time were investigated during egg transit, storage, and display. A predictive model was developed to characterize the kinetic behavior of Salmonella in eggs, and data on egg consumption and frequency were collected. Eventually, the data was simulated to estimate egg-related foodborne illnesses. Salmonella was not found in any of the 201 egg samples. Thus, the estimated initial contamination level was -4.0 Log CFU/g. With R2 values of 0.898 and 0.922, the constructed predictive models were adequate for describing the fate of Salmonella in eggs throughout distribution and storage. Eggs were consumed raw (1.5%, 39.2 g), dry-heated (57.5%, 43.0 g), and moist-heated (41%, 36.1 g). The probability of foodborne Salmonella illness from the consumption of cooked eggs was evaluated to be 6.8×10-10. Additionally, the probability of foodborne illness not applied cooking methods was 1.9×10-7, indicating that Salmonella can be reduced by cooking. Therefore, the risk of Salmonella infection through consumption of eggs after cooking might be low in S. Korea.

Glutamic Acid-Grafted Metal-Organic Framework: Preparation, Characterization, and Heavy Metal Ion Removal Studies

  • Phani Brahma Somayajulu Rallapalli;Jeong Hyub Ha
    • Applied Chemistry for Engineering
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    • v.34 no.5
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    • pp.556-565
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    • 2023
  • Fast industrial and agricultural expansion result in the production of heavy metal ions (HMIs). These are exceedingly hazardous to both humans and the environment, and the necessity to eliminate them from aqueous systems prompts the development of novel materials. In the present study, a UIO-66 (COOH)2 metal-organic framework (MOF) containing free carboxylic acid groups was post-synthetically modified with L-glutamic acid via the solid-solid reaction route. Pristine and glutamic acid-treated MOF materials were characterized in detail using several physicochemical techniques. Single-ion batch adsorption studies of Pb(II) and Hg(II) ions were carried out using pristine as well as amino acid-modified MOFs. We further examined parameters that influence removal efficiency, such as the initial concentration and contact time. The bare MOF had a higher ion adsorption capacity for Pb(II) (261.87 mg/g) than for Hg(II) ions (10.54 mg/g) at an initial concentration of 150 ppm. In contrast, an increased Hg(II) ion adsorption capacity was observed for the glutamic acid-modified MOF (80.6 mg/g) as compared to the bare MOF. The Hg(II) ion adsorption capacity increased by almost 87% after modification with glutamic acid. Fitting results of isotherm and kinetic data models indicated that the adsorption of Pb(II) on both pristine and glutamic acid-modified MOFs was due to surface complexation of Pb(II) ions with available -COOH groups (pyromellitic acid). Adsorption of Hg(II) on the glutamic acid-modified MOF was attributed to chelation, in which glutamic acid grafted onto the surface of the MOF formed chelates with Hg(II) ions.

Atmospheric Boundary Layer Height Estimated based on 1.29 GHz Pulse Wave (1.29 GHz 펄스파로 산출한 대기경계층 고도)

  • Zi-Woo Seo;Byung-Hyuk Kwon;Kyung-Hun Lee;Geon-Myeong Lee
    • The Journal of the Korea institute of electronic communication sciences
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    • v.18 no.6
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    • pp.1049-1056
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    • 2023
  • The height of the atmospheric boundary layer indicates the peak developed when turbulence is generated by mixing heat and water vapor, and is generally determined through thermodynamic methods. Wind profilers produce atmospheric information from the scattering of signals sent into the atmosphere. A method for making the spectrum of turbulent components, turbulent kinetic energy dissipation rate, and refractive index structure coefficient was presented to determine the atmospheric boundary layer depth. Compared with the vertical distribution characteristics of potential temperature and specific humidity based on radiosonde data, the determination method of the atmospheric boundary layer height from wind profiler output was evaluated as very useful.

LOW REGULARITY SOLUTIONS TO HIGHER-ORDER HARTREE-FOCK EQUATIONS WITH UNIFORM BOUNDS

  • Changhun Yang
    • Journal of the Chungcheong Mathematical Society
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    • v.37 no.1
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    • pp.27-40
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    • 2024
  • In this paper, we consider the higher-order HartreeFock equations. The higher-order linear Schrödinger equation was introduced in [5] as the formal finite Taylor expansion of the pseudorelativistic linear Schrödinger equation. In [13], the authors established global-in-time Strichartz estimates for the linear higher-order equations which hold uniformly in the speed of light c ≥ 1 and as their applications they proved the convergence of higher-order Hartree-Fock equations to the corresponding pseudo-relativistic equation on arbitrary time interval as c goes to infinity when the Taylor expansion order is odd. To achieve this, they not only showed the existence of solutions in L2 space but also proved that the solutions stay bounded uniformly in c. We address the remaining question on the convergence of higherorder Hartree-Fock equations when the Taylor expansion order is even. The distinguished feature from the odd case is that the group velocity of phase function would be vanishing when the size of frequency is comparable to c. Owing to this property, the kinetic energy of solutions is not coercive and only weaker Strichartz estimates compared to the odd case were obtained in [13]. Thus, we only manage to establish the existence of local solutions in Hs space for s > $\frac{1}{3}$ on a finite time interval [-T, T], however, the time interval does not depend on c and the solutions are bounded uniformly in c. In addition, we provide the convergence result of higher-order Hartree-Fock equations to the pseudo-relativistic equation with the same convergence rate as the odd case, which holds on [-T, T].

Protective Effects of Changbudodam-tang on Cell Death Signals on the Bone Marrow-Derived Human Mesenchymal Stem Cells via Regulation of MKK7/JNK/c-Jun Signaling Pathway

  • Hee-Jae Yoon;Si-Yoon Cho;Hyeong-Geug Kim;Ji-Yeon Lee
    • Journal of Pharmacopuncture
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    • v.27 no.2
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    • pp.131-141
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    • 2024
  • Objectives: Polycystic ovary syndrome (PCOS) is one of the most common disorders and it shows up to 20% prevalence in reproductive-aged women populations, but no cures are available to date. We aimed to investigate the protective effects of Changbudodam-tang (CBD) on cell death signaling pathways, inflammation, and oxidative stress observed in Bone-Marrow derived human mesenchymal stem cell (BM-hMSC) by means of PCOS therapeutics in the future. Methods: BM-hMSCs were applied with cell deaths and injuries. Apoptosis and pyroptosis signals were quenched with their related signaling pathways using quantitative PCR, Western blot, and fluorescence image analysis. Results: Our data clearly displayed hydrogen peroxide- and nigericin-treated cell death signaling pathways via regulations of mitochondrial integrity and interleukin (IL)-1β at the cellular levels (p < 0.01 or 0.001). We further observed that pre-treatment with CBD showed protective effects against oxidative stress by enhancement of antioxidant components at the cellular level, with respect to both protein and mRNA expression levels (p < 0.05, 0.01 or 0.001). The mechanisms of CBD were examined by Western blot analysis, and it showed anti-cell death, anti-inflammatory, and antioxidant effects via normalizations of the Jun N-terminal kinase/mitogen-activated protein kinase kinase 7/c-Jun signaling pathways. Conclusion: This study confirmed the pharmacological properties of CBD by regulation of cellular oxidation and the inflammation-provoked cell death condition of BM-hMSCs, which is mediated by the MKK7/JNK/c-Jun signaling pathway.

The multigroup library processing method for coupled neutron and photon heating calculation of fast reactor

  • Teng Zhang;Xubo Ma;Kui Hu;GuanQun Jia
    • Nuclear Engineering and Technology
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    • v.56 no.4
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    • pp.1204-1212
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    • 2024
  • To accurately calculate the heating distribution of the fast reactor, a neutron-photon library in MATXS format named Knight-B7.1-1968n × 94γ was processed based on the ENDF/B-VII.1 library for ultrafine groups. The neutron cross-section processing code MGGC2.0 was used to generate few-group neutron cross sections in ISOTXS format. Additionally, the self-developed photon cross-section processing code NGAMMA was utilized to generate photon libraries for neutron-photon coupled heating calculations, including photo-atom cross sections for the ISOTXS format, prompt photon production cross sections, and kinetic energy release in materials (KERMA) factors for neutrons and photons, and the self-shielding effect from the capture and fission cross sections of neutron to photon have been taken into account when the photon source generated by neutron is calculated. The interface code GSORCAL was developed to generate the photon source distribution and interface with the DIF3D code to calculate the neutron-photon coupling heating distribution of the fast reactor core. The neutron-photon coupled heating calculation route was verified using the ZPPR-9 benchmark and the RBEC-M benchmark, and the results of the coupled heating calculations were analyzed in comparison with those obtained from the Monte Carlo code MCNP. The calculations show that the library was accurately processed, and the results of the fast reactor neutron-photon coupled heating calculations agree well with those obtained from MCNP.

Long-Term Science Goals with In Situ Observations at the Sun-Earth Lagrange Point L4

  • Dae-Young Lee;Rok-Soon Kim;Kyung-Eun Choi;Jungjoon Seough;Junga Hwang;Dooyoung Choi;Ji-Hyeon Yoo;Seunguk Lee;Sung Jun Noh;Jongho Seon;Kyung-Suk Cho;Kwangsun Ryu;Khan-Hyuk Kim;Jong-Dae Sohn;Jae-Young Kwak;Peter H. Yoon
    • Journal of Astronomy and Space Sciences
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    • v.41 no.1
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    • pp.1-15
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    • 2024
  • The Korean heliospheric community, led by the Korea Astronomy and Space Science Institute (KASI), is currently assessing the viability of deploying a spacecraft at the Sun-Earth Lagrange Point L4 in collaboration with National Aeronautics and Space Administration (NASA). The aim of this mission is to utilize a combination of remote sensing and in situ instruments for comprehensive observations, complementing the capabilities of the L1 and L5 observatories. The paper outlines longterm scientific objectives, underscoring the significance of multi-point in-situ observations to better understand critical heliospheric phenomena. These include coronal mass ejections, magnetic flux ropes, heliospheric current sheets, kinetic waves and instabilities, suprathermal electrons and solar energetic particle events, as well as remote detection of solar radiation phenomena. Furthermore, the mission's significance in advancing space weather prediction and space radiation exposure assessment models through the integration of L4 observations is discussed. This article is concluded with an emphasis on the potential of L4 observations to propel advancements in heliospheric science.

A Case Study on Near-Cloud Turbulence around the Mesoscale Convective System in the Korean Peninsula (한반도에서 발생한 중규모 대류계의 구름 주변 난류 발생 메커니즘 사례 연구)

  • Sung-Il Yang;Ju Heon Lee;Jung-Hoon Kim
    • Atmosphere
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    • v.34 no.2
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    • pp.153-176
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    • 2024
  • At 0843 UTC 30 May 2021, a commercial aircraft encountered severe turbulence at z = 11.5 km associated with the rapid development of Mesoscale Convective System (MCS) in the Gyeonggi Bay of Korea. To investigate the generation mechanisms of Near-Cloud Turbulence (NCT) near the MCS, Weather Research and Forecasting model was used to reproduce key features at multiple-scales with four nested domains (the finest ∆x = 0.2 km) and 112 hybrid vertical layers. Simulated subgrid-scale turbulent kinetic energy (SGS TKE) was located in three different regions of the MCS. First, the simulated NCT with non-zero SGS TKE at z = 11.5 km at 0835 UTC was collocated with the reported NCT. Cloud-induced flow deformation and entrainment process on the downstream of the overshooting top triggered convective instability and subsequent SGS TKE. Second, at z = 16.5 km at 0820 UTC, the localized SGS TKE was found 4 km above the overshooting cloud top. It was attributed to breaking down of vertically propagating convectively-induced gravity wave at background critical level. Lastly, SGS TKE was simulated at z = 11.5 km at 0930 UTC during the dissipating stage of MCS. Upper-level anticyclonic outflow of MCS intensified the environmental westerlies, developing strong vertical wind shear on the northeastern quadrant of the dissipating MCS. Three different generation mechanisms suggest the avoidance guidance for the possible NCT events near the entire period of the MCS in the heavy air traffic area around Incheon International Airport in Korea.

Geometry optimization of a double-layered inertial reactive armor configured with rotating discs

  • Bekzat Ajan;Dichuan Zhang;Christos Spitas;Elias Abou Fakhr;Dongming Wei
    • Advances in Computational Design
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    • v.8 no.4
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    • pp.309-325
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    • 2023
  • An innovative inertial reactive armor is being developed through a multi-discipline project. Unlike the well-known explosive or non-explosive reactive armour that uses high-energy explosives or bulging effect, the proposed inertial reactive armour uses active disc elements that is set to rotate rapidly upon impact to effectively deflect and disrupt shaped charges and kinetic energy penetrators. The effectiveness of the proposed armour highly depends on the tangential velocity of the impact point on the rotating disc. However,for a single layer armour with an array of high-speed rotating discs, the tangential velocity is relatively low near the center of the disc and is not available between the gap of the discs. Therefore, it is necessary to configure the armor with double layers to increase the tangential velocity at the point of impact. This paper explores a multi-objective geometry design optimization for the double-layered armor using Nelder-Mead optimization algorithm and integration tools of the python programming language. The optimization objectives include maximizing both average tangential velocity and high tangential velocity areas and minimizing low tangential velocity area. The design parameters include the relative position (translation and rotation) of the disc element between two armor layers. The optimized design results in a significant increase of the average tangential velocity (38%), increase of the high tangential velocity area (71.3%), and decrease of the low tangential velocity area (86.2%) as comparing to the single layer armor.

The preparation of surface-modified granular activated carbon (GAC) to enhance Perfluorooctanoic acid (PFOA) removal and evaluation of adsorption behavior (입상 활성탄 표면 개질을 통한 과불화옥탄산 (PFOA) 제거 향상 및 특성 평가)

  • Jeongwoo Shin;Byungryul An
    • Journal of Korean Society of Water and Wastewater
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    • v.37 no.4
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    • pp.177-186
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    • 2023
  • Perfluorooctanoic acid(PFOA) was one of widely used per- and poly substances(PFAS) in the industrial field and its concentration in the surface and groundwater was found with relatively high concentration compared to other PFAS. Since various processes have been introduced to remove the PFOA, adsorption using GAC is well known as a useful and effective process in water and wastewater treatment. Surface modification for GAC was carried out using Cu and Fe to enhance the adsorption capacity and four different adsorbents, such as GAC-Cu, GAC-Fe, GAC-Cu(OH)2, GAC-Fe(OH)3 were prepared and compared with GAC. According to SEM-EDS, the increase of Cu or Fe was confirmed after surface modification and higher weight was observed for Cu and Fe hydroxide(GAC-Cu(OH)2 and GAC-Fe(OH)3, respectively). BET analysis showed that the surface modification reduced specific surface area and total pore volumes. The highest removal efficiency(71.4%) was obtained in GAC-Cu which is improved by 17.9% whereas the use of Fe showed lower removal efficiency compared to GAC. PFOA removal was decreased with increase of solution pH indicating electrostatic interaction governs at low pH and its effect was decreased when the point of zero charges(pzc) was negatively increased with an increase of pH. The enhanced removal of PFOA was clearly observed in solution pH 7, confirming the Cu in the surface of GAC plays a role on the PFOA adsorption. The maximum uptake was calculated as 257 and 345 ㎍/g for GAC and GAC-Cu using Langmuir isotherm. 40% and 80% of removal were accomplished within 1 h and 48 h. According to R2, only the linear pseudo-second-order(pso) kinetic model showed 0.98 whereas the others obtained less than 0.870.