• Clinical and Experimental Pediatrics
• /
• v.53 no.1
• /
• pp.41-47
• /
• 2010

Purpose : Adiponectin is an endogenous modulator of vascular remodeling that suppresses vascular inflammation. However, the role of adiponectin in Kawasaki disease (KD) has not been elucidated. The purpose of this study is to investigate the correlation between serum adiponectin level and several parameters, such as interleukin (IL)-6, tumor necrosis factor $(TNF)-{\alpha}$, lipid profile, and C reactive protein (CRP), and to clarify the association between adiponectin and cardiac function. Methods : Twenty-two KD patients (22 patients in acute phase and 20 patients in subacute phase) were enrolled in the study group. The control group consisted of 31 subjects (13 febrile patients and 18 healthy children). Both groups underwent blood sampling and tissue Doppler imaging (TDI). Results : CRP was significantly increased in the KD group compared with the control group. There were no significant differences in serum $TNF-{\alpha}$, IL-6, and adiponectin levels between groups. However, a negative correlation was found between adiponectin level and CRP level or platelet count. Systolic myocardial velocity and A myocardial velocity measured by TDI were decreased significantly in the acute KD group compared with the subacute KD group and control group. Positive correlations were found between adiponectin level and systolic myocardial velocity or A myocardial velocity. Conclusion : In acute KD patients, low adiponectin level was related to severe inflammatory reactions and decreased left ventricular functions.

• Journal of Pharmaceutical Investigation
• /
• v.19 no.2
• /
• pp.71-79
• /
• 1989

Complex formation of water-soluble polyparacyclophanes bearing two diphenylmethane or two diphenyl ether skeletons with l-anilinonaphthalene-8-sulfonate (ANS) and 2-p-toluidinylnaphthalene-6-sulfonate (TNS) was investigated quantitatively to develop useful host compounds comparing with ${\alpha}\;-\;and\;{\beta}-cyc1odextrins$$({\alpha}-\;and\;{\beta}-CyDs$) in aqueous solution. Benesi-Hildebrand type analysis of the fluorescent intensity showed that the dissociation constants (Kd) of paracyclophane-ANS complexes were $1.55\;{\times}\;10^{-4}M$ for 1,6,20,25-tetraaza[6.1.6.1]paracyclophane(CPM 44) and $1.23\;{\times}\;10^{-4}M$ for 1,7,21,27-tetraaza[7.1.7.1]paracyclophane (CPM 55), and those of paracyclophane-TNS complexes were $6.99\;{\times}\;10^{-6}M$ for CPM 44 and $6.23\;{\times}\;10^{-5}M$ for CPM 55, in 1:1 molar ratio. On the other hand, the Kd values of 1,7,21,27-tetraaza-14,34-dioxa[7.1.7.1]paracyclophane (CPE 55)-ANS, 1,8,22,29-tetraaza-15,36-dioxa[8.1.8.1]paracyclophane (CPE 66)-ANS, CPE 55-TNS, CPE 66-TNS complexes were $1.75\;{\times}\;10^{-3}M$, $3.07\;{\times}\;10^{-3}M$, $3.75\;{\times}\;10^{-3}M$ and $2.15\;{\times}\;10^{-3}M$, respectively. On the contrary, the Kd values of ${\alpha}-CyD-ANS$, ${\beta}-CyD-ANS$, ${\alpha}-CyD-TNS$ and ${\beta}-CyD-TNS$ complexes were found to be $3.98\;{\times}\;10^{-2}M$, $1.05\;{\times}\;10^{-2}M$, $1.38\;{\times}\;10^{-2}M$ and $3.52\;{\times}\;10^{-4}M$, respectively. These results mean that the complexation of CPMs with ANS or TNS is by 5.6-1,975 fold stronger than that for ${\alpha}-or\;{\beta}-CyDs$, and the complex formation of CPEs with ANS or TNS is nearly same as or somewhat stronger than that for ${\alpha}-or\;{\beta}-CyDs$. From the Kd values determined at different temperatures, thermodynamic parameters were calculated and the complexation was found to be a spontaneous exothermic reaction. The effects of pH on Kd values of CPM 44-ANS, and CPM 55-ANS complexes were negligible in the range of pH 1.2-1.8. However, the Kd values of these complexes increased significantly with increasing ionic strength.

• Applied Chemistry for Engineering
• /
• v.34 no.1
• /
• pp.69-74
• /
• 2023

As a chemical de-icing method, propylene glycol de-icing fluid is applicable for melting ice caused by snow and ice adhering to the lower part of high-speed rail rolling stock and bogie parts in winter. By spraying propylene-glycol de-icing fluid on high-speed rail rolling stock and bogie parts in advance to minimize snow adhesion, ice-melting efficiency can be further improved. In the case of high-speed rail rolling stock, even if propylene-glycol de-icing fluid is sprayed, the anti-icing performance is poor because the fluid is almost lost on the surface of the vehicle when operating at high speed. In this study, in order to prevent freezing caused by snow and ice adhering to the lower part of high-speed rail rolling stock and bogie parts, we have investigated the properties of propylene-glycol de/anti-icing fluid containing water-repellent agents that prevent surface freezing. We tried to find the optimal component for de/anti-icing fluid for high-speed rail rolling stock by evaluating the ice melting performance, contact angle, and anti-icing performance according to the types of water-repellent agent. As a result of the evaluation, it was confirmed that an de/anti-icing fluid containing an ethoxysilane-type water repellent agent was most suitable.

• Pediatric Infection and Vaccine
• /
• v.30 no.3
• /
• pp.139-144
• /
• 2023

Purpose: Children with incomplete Kawasaki disease (KD) and pyuria may be misdiagnosed with urinary tract infection (UTI) during the early phase of the prodrome. We investigated the percentage of UTI diagnoses preceding a KD diagnosis. Methods: Using the National Health Insurance data of South Korea, we assessed differences in UTI diagnoses made during the week preceding a KD diagnosis, according to demographic and geographic factors from November 2007-October 2019. Results: A total of 53,822 KD cases were identified, including 304 patients (0.56%) diagnosed with a UTI during the week preceding a KD diagnosis. The younger age group (0-11 months) showed the highest percentage of preceding UTI diagnoses (0.95%), with higher odds than 4-year-old children (3.12; 95% confidence interval, 2.05-4.77). Conclusions: These findings suggest a potentially misleading presentation of incomplete KD, a clinical conundrum requiring further investigation and validation, particularly in infants.

• Journal of applied mathematics & informatics
• /
• v.31 no.1_2
• /
• pp.229-239
• /
• 2013

This paper studies the generalized fifth-order KdV equation with variable coefficients using Lie symmetry methods.Lie group classification with respect to the time dependent coefficients is performed. Then we get the similarity reductions using the symmetry and give some exact solutions.

• 한국전산유체공학회:학술대회논문집
• /
• 1995.10a
• /
• pp.126-131
• /
• 1995

In this paper we study steady capillary-gravity waves in a two-layer fluid bounded above by a free surface and below by a horizontal rigid boundary with a small obstruction, Two critical speeds for the waves are obtained. Near the smaller critical speed, the derivation of the usual forced KdV equation (FKdV) fails when the coefficient of the nonlinear term in the FKdV vanishes. To overcome this difficulty, a new equation called a forced extended KdV equation (FEKdV) governing interfacial wave forms is obtained by a refined asymptotic method. Various solutions and numerical results of this equation are presented.

• Proceedings of the KIEE Conference
• /
• 2015.07a
• /
• pp.1090-1091
• /
• 2015

사막은 일조량이 많고, 세계적으로 넓은 규모를 가지고 있어 대규모 태양광 발전소 건설에 주목받고 있지만, 태양광 모듈 표면에 쌓이는 모래먼지로 인하여 발전효율 저하가 발생되고 있는 실정이다. 이에 태양광 모듈 표면의 모래먼지를 제거할 수 있는 태양광 모듈 크리닝 시스템을 개발 하였다. 본 논문에서는 사막 환경을 고려하여 물을 필요로 하지 않는 압축공기 및 회전하는 브러쉬로 모듈 표면을 세척하는 Solar Module Cleaning System을 제안한다.

• The Korean Journal of Ecology
• /
• v.21 no.6
• /
• pp.771-777
• /
• 1998

Aqueous extracts of Pinus rigida changed the electrophoretic patterns of total proteins and of hydrolytic enzymes such as peroxidase, esterase and amylase during the germination of radish (Raphanus sativus var. hortensis for. acanthiformis). When the extract treatment was finished, at the late stage of radish germination, aqueous extracts of P. rigida had suppressed the expression of 24 KD and 60 KD proteins. the extract induced new isozyme bands, indicating concomitant activity of peroxidases, esterase activities were stimulated in the cathodic region. The activity of amylase was enhanced by the extract.

• Journal of the Chungcheong Mathematical Society
• /
• v.24 no.2
• /
• pp.359-370
• /
• 2011

In this work, we obtain new solitary wave solutions for some nonlinear partial differential equations. The Jacobi elliptic function rational expansion method is used to establish new solitary wave solutions for the combined KdV-mKdV and Klein-Gordon equations. The results reveal that Jacobi elliptic function rational expansion method is very effective and powerful tool for solving nonlinear evolution equations arising in mathematical physics.

• Clinical and Experimental Pediatrics
• /
• v.62 no.4
• /
• pp.119-123
• /
• 2019

Kawasaki disease (KD) is a systemic vasculitis that mainly affects younger children. Intravenous immunoglobulin (IVIG) resistant cases are at increasing risk for coronary artery complications. The strategy on prediction of potential nonresponders and treatment of IVIG-resistant patients is now controversial. In this review the definition and predictors of IVIG-resistant KD and current evidence to guide management are discussed.