• Title/Summary/Keyword: KCI

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Effect of $Ca^{++}$ on High K-induced Contracture of Isolated Frog Ventricular Muscle (적출 심근의 칼륨경축에 대한 칼슘이온 효과)

  • Choi, Youn-Baik;Kim, Ki-Whan
    • The Korean Journal of Physiology
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    • v.20 no.1
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    • pp.31-41
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    • 1986
  • The sufficient myoplasmic $Ca^{++}$ to react with the contractile proteins is necessary to induce contraction of a cardiac muscle. These $Ca^{++}$ for the production of muscle contraction are supplied from the three recognized $Ca^{++}$ sources; internal $Ca^{++}$ release via the sarcoplasmic reticulum(SR), $Ca^{++}$ influx through a gated Ca-channel in the membrane as a Isi, and $Ca^{++}$ transport by the mechanism of Na/ca exchange. However, it is still controversial which $Ca^{++}$ sources act as a main contributor for myoplasmic $Ca^{++}$, Therefore, this study was undertaken in order to examine the $Ca^{++}$ sources for the contraction of frog ventricle. There is evidence that the SR is sparse in frog ventricular fibers, and that T-tubules are absent. Isolated ventricular strips of frog, Rana nigromaculata, were used in this experiment. Isometric tension was recorded by force transducer, and membrane potentials of ventricular muscles were measured through the intracellular glass microelectrodes, which were filled with 3M KCI and had resistance of $30{\pm}50M{\Omega}$. All experiments were performed at room temperature in a tris·buffered Ringer solution which was aerated with 100% $O_2$. Isotonic high K, low Na solution was used to induce K-contracture, K-contracture appeared at the concentration of 20 to 30mM-KCI and was potentiated in parallel with the increase in KCI concentration. The contracture had two components: an initial rapid phasic and a subsequent slow tonic contractile responses. Membrane Potentials measured at normal Ringer solution(2.5mM KCI) was -90 to -100 mV, and decreased linearly as the KCI concentration increased; -55mV at 20mM.KCI, -45mV at 30 mM.KCI, -30 mY at 50 mM.KCI, and -12 mV at 100 mM.KCI. K-contracture was evoked firstly at the membrane potential of -45 mV. The contracture was potentiated by the increase of bathing extracellular $Ca^{++}$ concentration. However, in the absence of $Ca^{++}$ the contracture was almost not induced by 50 mM.KCI solution. Caffeine(20mM) in normal Ringer solution, which is known to release $Ca^{++}$ from SR without substantial effects on the $Ca^{++}$ fluxes across the surface membrane, did not affect membrane potential and also not initiate contracture, but the caffeine in 20 mM-KCI Ringer solution produced a contracture. Above results suggest that the main $Ca^{++}$ source for the K·contracture of frog ventricle is $Ca^{++}$ influx through the voltage-dependent Ca-channel, and that in the K-contracture at the concentration of 100 mM-KCI, the mechanism of Na/ca exchange also partly contributs, in addition to the $Ca^{++}$ influx.

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2008-2014 KCI indicators trend analysis (2008-2014 KCI 인용지표 변화 분석)

  • Lee, Jae Yun
    • Proceedings of the Korean Society for Information Management Conference
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    • 2016.08a
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    • pp.9-13
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    • 2016
  • 한국학술지인용색인 KCI의 인용지표가 본격 서비스된 것은 2008년 이후로서 최근 2014년 인용지수가 발표되었다. 7년 동안의 영향력 지수를 비롯하여 KCI가 제공하는 IF 지수와 자기인용율 등의 인용지표 변화 추세를 인문학, 사회과학, 예술체육, 복합학의 4개 인문사회 계열과 자연과학, 공학, 농수해양, 의약학의 4개 공학 계열로 나누어 분석하여 국내 학술지 생태계의 변화를 부분적으로 살펴보고자 하였다.

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Sensory Characteristics of Low Sodium Kakdugi (저염 깍뚜기의 관능적 특성)

  • Kim, In-Hye;Kim, Kwang-Ok
    • Korean Journal of Food Science and Technology
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    • v.22 no.4
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    • pp.380-385
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    • 1990
  • This study was conducted to determine the relative saltiness of $MgCl_2,\;K_{2}SO_4$ and KCl and evaluate the sensory characteristics of solutions and Kakdugi (Korean seasoned pickles of cubed radish roots) prepared with reduced amount of sodium chloride by replacement with varying levels of KCI. The relative saltiness of $MgCl_2$ and $K_{2}SO_4$, were $0.11{\sim}0.12(0.115)$ and $0.08{\sim}0.09(0.085)$ respectively, at the reference level of 0.5% NaCl. The relative saltiness of KCI varied from 0.52 to 0.76 as the reference level increased from 0.5 to 2.0% NaCl. The result of sensory evaluation on the mixed solutions of NaCl and KCI indicated that bitterness, metallic flavor and astringency increased with the increased levels of KCI. The addition of KCI slightly increased the firmness of kakdugi but there was no significant difference in firmness by the amount of substitution. Bitterness and off-flavor was enhanced with the increased levels of replacement especially when the level was higher than 50%. Saltiness, sourness and overall desirability decreased as the extent of the replacement increased. There were no significant difference in pH, acidity and firmness measured with Universal Testing Machine. The result of this study indicate that the replacement of NaCl with KCI at not more than 50% does not affect greatly the characteristics of kakdugi.

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Regeneration of Yeast Protoplast in Hansenula anomala var. anomala and Saccharomyces cerevisiae (Hansenula anomala var. anomala와 Saccharomyces cerevisiae의 원형질체 재생에 관한 연구)

  • 구영조;박완수;신동화;유태종
    • Microbiology and Biotechnology Letters
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    • v.13 no.2
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    • pp.145-149
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    • 1985
  • Studies were conducted on the conditions for yeast protoplast regeneration in Hansenula anomala var.anomala FRI YO-32 and Saccharomyces cerevisiae. Protoplasts lysed when suspended in hypotonic solutions of KCI, and the least degree of osmolysis was shown in the hypertonic solution containing 1.4M KCI for the strain FRI YO-32 or 0.8M KCI for S. cerevisiae. It was considered that the concentration of agrar and KCI, and protoplast plating method were the main factors influencing regeneration of yeast protoplasts. Yeast protoplasts were regenerated very favorably when embedded in the complete protoplast regeneration media containing 3% agar as well as 0.4M KCI for the strain FRI YO-32 or 1.0M KCI for S. cerevisiae. It was shown from the relationship between protoplast formation and regeneration that the higher extent of protoplast formation, the lower extent of protoplast regeneration.

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A Study on the Flexural Minimum Reinforcement for Prevention of Brittle Failure Specified in KCI and EN Codes (유럽과 국내기준에 규정된 취성파괴 방지를 위한 휨 최소철근량 고찰)

  • Park, Sung-Jae;Kang, Tae-Sung;Moon, Do-Young
    • Journal of the Korea Concrete Institute
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    • v.26 no.2
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    • pp.211-218
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    • 2014
  • In the design of reinforced rectangular concrete beam structure, the minimum amount of flexural reinforcement is required to avoid brittle failure. KCI code is based on concept of ultimate strength and usually used as a model code. But bridge design code enacted by Ministry of land, transportation and maritime affairs in 2012 is based on concept of limit state and similar to Euro code EN 1992-2. This means that the minimum reinforcement presented in both design codes has different origination and safety margin. When rectangular concrete beams with minimum reinforcement are designed according to EN and KCI codes, the amount of minimum reinforcement specified in EN code is only 76% of that in KCI code. This makes the design engineers to be confused. In this study, flexural tests were conducted on nine beams with the two different minimum reinforcement specified in KCI and EN design codes. In results, the measured ratios of nominal strength to crack strength from the test were about 25% greater than those evaluated from the equations presented in KCI and EN codes. The EN beams having only 76% of the minimum reinforcement for the KCI beams were fractured by rupture of steel reinforcement but in ductile manner. It is confirmed that the minimum reinforcement concrete beams designed according to both codes have enough safety margin in flexural capacity and moreover in ductility.

Analysis of Research Trends in Home Economics Education by Language Network Analysis: Focused on the KCI Journals (2000-2019) (언어 네트워크 분석에 기반 한 가정과교육 연구 동향 분석: 2000-2019년 KCI 등재지를 중심으로)

  • Gham, Kyoung Won;Park, Mi Jeong
    • Journal of Korean Home Economics Education Association
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    • v.32 no.3
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    • pp.179-197
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    • 2020
  • This study analyzed the trends in home economics education research using the language network analysis method, focusing on papers published in the KCI list for 20 years from 2000 to 2019. A total of 501 home economics education papers analyzed through word cloud, centrality analysis, and topic modeling using NetMiner 4.4, and the results are as follows. First, the number of papers in home economics education published in the KCI listing increased gradually to 186 in the 2000s and 315 in the 2010s. The academic journals in which home economics education papers were published have been diversified to 16 in the 2000s and 22 in the 2010s. 60% of all papers were published in the 'Journal of Korean Home Economics Education Association', and since 2018, the number of papers published in the 'Journal of Learner-Centered Curriculum and Instruction' has increased dramatically. Second, in the 2000s and 2010s, home economics education studies published in KCI were categorized into home economics education content analysis, home economics educational program development & application, curriculum analysis, perception survey & direction exploration. In the 2000s, 'Home Economics Teacher' appeared as the main keyword, and a lot of perception survey & direction exploration were conducted. Relatively, the influence of 'development' increased in the 2010s, and many studies were conducted to analyze home economics education contents and develop and apply home economics programs. This study has significance in that it analyzed the research trend of HEE by expanding the analysis target and analysis period of the existing studies.

Improved Method for Considering Citation Measures in Evaluating Korean Journals (국내 학술지평가에서 인용지수 반영 방법의 개선방안)

  • Lee, Jae Yun
    • Journal of the Korean Society for information Management
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    • v.37 no.1
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    • pp.197-220
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    • 2020
  • Recently, the National Research Foundation of Korea (NRF) announced new plan to reflect the KCI citation measures in journal evaluation. In principle, Journal evaluation should reflect each journals situation and characteristics through various indicators. In this study, three improvement plans were proposed by reviewing the announced journal evaluation plan of NRF. The first improvement is to consider the five-year IF as an additional citation measure; the second improvement is to allow flexible selection of the category level on which to rank journals; and the last improvement is to combine the previous two methods and apply them together. The improvement methods proposed in this study are expected to contribute to minimizing side effects of KCI journal evaluation.

Uniaxial Behavior of Reinforced Concrete Column with Replacement Levels of Recycled Aggregate (순환골재 치환율에 따른 철근콘크리트 기둥의 압축거동 특성)

  • Nam, Sang-Hyun;Jang, Gwang-Soo;Yun, Hyun-Do;Choi, Ki-Sun;You, Young-Chan;Kim, Keung-Hwan
    • Proceedings of the Korea Concrete Institute Conference
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    • 2009.05a
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    • pp.33-34
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    • 2009
  • In this paper, Recycled aggregate replacement levels were considered. Five columns are tested under axial load. Compressive strength of reinforced concrete columns with recycled aggregate showed higher than that provided in KCI 2007. The KCI provision were conservative and subsequently can be used for design of reinforced recycled aggregate concrete column.

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Periods of Cold Weather Concrete Determined by Korean and Japanese Codes with Climate Data Obtained from Korea (우리나라 한중콘크리트 적용 기간의 KCI와 AIJ 규정에 따른 비교)

  • Lee, Myung-Ho;Zhao, Yang;Park, Jun-Hee;Han, Min-Cheol;Han, Cheon-Goo
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2013.05a
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    • pp.326-328
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    • 2013
  • This study compares the periods of cold weather concrete determined by the codes regulated by KCI (Korean Concrete Institute) and AIJ (Architectural Institute of Japan). For the calculation of the periods of cold weather concrete, the climate data for last 5 years obtained from Korean weather forecast station is used. Calculated data indicated that the period of cold weather concrete by AIJ code is longer than that by KCI code. Although global warming causes the decrease of the period of winter season, the temperature differences are large in Korea. Therefore, it is required that the current KCI code should be accordingly upgraded to reflect the weather variation in Korea over time.

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Calibration of Load and Resistance Factors in KCI Code Based on Domestic Data (국내 통계자료를 이용한 설계기준의 하중저항계수 검증)

  • Kim, Jee-Sang;Kim, Jong-Ho
    • Journal of the Korea Concrete Institute
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    • v.23 no.4
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    • pp.495-501
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    • 2011
  • The load combinations in current KCI Design Code are determined with reference to those in ACI 318-05, which adopts the LRFD (load and resistance factor design) format. The load and resistance factors in LRFD format should be determined to meet the required levels of reliability index or probability of failure for various predetermined failure modes, which are also based on the statistical data reflecting locality and contemporary situation. However, the current KCI Design Code has been written utilizing foreign data, because of insufficiency in accrued data in Korea. This study considered the current safety levels of KCI Code based on published domestic data to evaluate appropriateness of the current KCI regulations. Based on the calibrated reliability index of the existing Code, the new resistance factors are suggested. The results presented in this paper can be considered as a basic research for establishment of unique design format for future Korean Codes.