• Journal of Ginseng Research
• /
• v.32 no.1
• /
• pp.1-7
• /
• 2008

Ginseng saponin has been shown to inhibit the development of dependence on morphine, cocaine, methamphetamine, but the antinarcotics effects of ginseng on nalbuphine remains still largely unknown. Ginseng administration attenuated the naloxone-induced jumping behavior on nalbuphine dependent mice. The development of morphine dependence was mediated through ${\mu}-opioid$ receptor, however, development of nalbuphine dependence was mediated through ${\kappa}-opioid$ receptor. However, it was found that the efficacy of analgesic antagonism of GTS was mediated through the serotonergic mechanism, not mediated through the opioid receptor. In addition, ginseng administration modulated cellular signal transduction in the brain. The increased NMDA receptor subunit (NR1, pNR1), phosphate extracellular signal regulated protein kinase (pERK), phosphate cAMP response element binding protein (pCREB) expression by nalbuphine was decreased by the administration of ginseng powder in cortex, hippocampus, striatum of rat brain. These results suggest that ginseng could be one of the targets of antinarcotic therapies to reduce the development of tolerance and dependence on nalbuphine as well as morphine.

• The Transactions of the Korean Institute of Electrical Engineers D
• /
• v.51 no.12
• /
• pp.571-576
• /
• 2002

This paper is to develop jumping ring system with three sensor arrays and to control levitated ring using dynamic neural mode. Placing an aluminum ring on the core and switching on an AC source causes the ring to jump in the air due to induced currents. The educational system is composed of 40th optical sensor array, encode circuit, 89C51 microprocessor and control board. The control board consists of power IC, and phase controller. Real time process is present to obtain a height of levitated ring for three different sensor arrays. Based on the educational system and the proposed dynamic neural mode, the height of levitation of the ring is controlled by reference signals. This paper focuses on real system controls using the dynamic neural mode with on line learning algorithm.

• YAKHAK HOEJI
• /
• v.29 no.1
• /
• pp.27-31
• /
• 1985

The administraction of ginseng butanol fraction(GBF) inhibited the development of tolerance to and physical dependence on morphine induced by morphine multiple injections in mice. Each group of mice was injected with morphine hydrochloride (40mg/kg s.c.) three times at 8 hr intervals for a period of 6 days. GBF (25, 50, 100, 200mg/kg) was injected (i.p.) to mice 1hr prior to the third morphine injection daily. Inhibition of morphine tolerance by GBF was evidenced by the increase in analgesic response to morphine hydrochloride (10mg/kg) as estimated by the tail flick method and the reduction in morphine dependence was estimated by the decreased number of the naloxone induced withdrawal jumping mice. Further evidenced that GBF reduced the development of morphine dependence was indicated by the fact that GBF decreased the loss in body weight.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2007.11a
• /
• pp.117-120
• /
• 2007

The floor slabs of building structures are often subjected to the periodic force which is induced by vibrating machines or human activity(walking, jumping, running etc). These periodic forces cause excessive oscillation. In order to examine the dynamic characteristics of floor slabs, the dynamic characteristics test is accomplished. Generally, the Impact Hammer and Dynamic Exciter test is used to dynamic characteristics test. But the Impact Hammer test is not suitable to apply in building slabs. In this paper, It compared the performance of the Exciter and Impact Hammer test for dynamic characteristics analysis of floor slabs.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2006.11a
• /
• pp.366-370
• /
• 2006

In this study, characteristics of impact force and impact sound of impact source such as bang machine, impact ball, and children's jumping were review. Results of review showed that impact ball has most similar characteristic to real impact sources in terms of objective properties such as impact force and impact sound. The effects of various isolator on floor impact sound were also investigated in apartment building and test facilities building using bang machine an impact ball. From the field measurement, it was found that the difference in reduction sound level between bang machine and impact ball was relatively large and the reduction sound level by impact ball was much larger than bang machine.

• Proceedings of the Korean Institute of Intelligent Systems Conference
• /
• 2001.12a
• /
• pp.153-156
• /
• 2001

This paper discusses a stochastic stabilization of Takagi-Sugeno (75) fuzzy system with Markovian input delay. The finite Markovian process is adopted to model the input delay of the overall control system. It is assumed that the zero and hold devices are used for control input. The continuous-time 75 fuzzy system with the Markovian input delay is discretized for easy handling delay, accordingly, the discretized 75 fuzzy system is represented by a discrete-time 75 fuzzy system with jumping parameters. The stochastic stabilizibility of the jump 75 fuzzy system is derived and formulated in terms of linear matrix inequalities (LMls).

• Korean Journal of Mathematics
• /
• v.17 no.4
• /
• pp.419-428
• /
• 2009

We show the existence of at least one nontrivial solution of the homogeneous mixed type nonlinear elliptic problem. Here mixed type nonlinearity means that the nonlinear part contain the jumping nonlinearity and the critical growth nonlinearity. We first investigate the sub-level sets of the corresponding functional in the Soboles space and the linking inequalities of the functional on the sub-level sets. We next investigate that the functional I satisfies the mountain pass geometry in the critical point theory. We obtain the result by the mountain pass method, the critical point theory and variational method.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.28 no.1
• /
• pp.31-39
• /
• 2004

This paper presents design solutions for cam type transfer unit in which feeding, lifting, and clamping motions are generated by cams. In order to achieve faster transfer motion, each designed cam must satisfy the given specifications such as velocity, acceleration, jerk, pressure angle, cam thickness, and torque. To reduce absolute torque magnitude and torque variation, a conjugate cam and a torque reduction cam are used respectively. The conjugate cam eliminates the redundant pre-load by using complementary cam to avoid jumping between a cam and a follower. The torque reduction cam reduces the torque variation by applying opposite torque to a cam shaft. The experimental result shows the reductions of the absolute torque value and torque variation. The improvement of working speed and life span of cam type transfer unit can be expected.

• Proceedings of the KSME Conference
• /
• 2007.05a
• /
• pp.399-402
• /
• 2007

In the previous research, it has been found that water strider's legs are strongly water repellent due to hierarchical structure of hydrophobic setae on the legs. Here we propose an answer why they should be so hydrophobic by showing that the work required to remove a floating hydrophobic cylinder from an interface depends very sensitively on the contact angle of the cylinder: superhydrophobic cylinders require relatively little work to remove them from an interface. Also we experimentally study the work required to lift a leg out of water with different contact angles and compare our experimental results with a theoretical prediction.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2002.11b
• /
• pp.468-473
• /
• 2002

The purpose of this study was to present the possible use of a new standard impactor, the rubber ball(so called, impact ball), and to assess its evaluation method as for heavy-weight impact in multi-story residential buildings, Several experiments were carried out to investigate the effect of the impact on noise propagation in reinforced concrete buildings. Then, the noise from the impact ball was psychoacoustically evaluated. The correlation between the L-value evaluation methods and auditory responses was also investigated. Results show that the ball noise is quite similar to the jumping noise. The noise level of ball is even higher than the bang machine noise, although it has much lower impact force. It was also found that L-indexing seems to bge inappropriate for evaluation of ball noise.