• 구강회복응용과학지
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• 제16권2호
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• pp.149-159
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• 2000

Occlusal disease is comparable to periodontitis in that it is generally not reversible. Occlusal disease, however, like periodontitis, often maintainable. It does itself to treatment and when restorative dentistry is utilized it becomes, in that sense, reversible. Moreover, a systematized and integrated approach will lead to a prognosis that is favorable and predictable. This approach facilitates development of optimum oral function, comfort, and esthetics, resulting in a satisfied patient. Such a systematized approach consists of four logical phase : (1) patient evaluation, (2) comprehensive analysis and treatment planning, (3) integrated and systematic reconstruction, and (4) postoperative maintenance. An integrated treatment plan is first developed on one set of diagnostic casts, properly mounted on a semiadjustable articulator using jaw relationship records. This is accomplished by using wax to make reconstructive modifications to the casts. These modified casts become the blueprint for planned occlusal changes and the fabrication of provisional restorations. The treatment goals are : (1) comfortably functioning temporomandibular joints and stomatognathic musculature, (2) adherence to the basic principle of occlusion advocated by Schuyler, (3) anterior guidance that is in harmony with the envelope of function, (4) restorations that will not violate the patient's neutral zone. This report shows the treatment procedures for a patient whose mandibular position has been altered due to posterior bite collapse. Migration of the maxillary anterior teeth had occurred, and the posterior occlusal contacts showed pathologic interference. Precise diagnosis using mounted casts was executed and prosthodontic reconstruction by the aid of an unconventional orthodontic correction on maxillary flaring was planned. An unconventional orthodontic correction can be accomplished by using preexisting natural teeth, which can be modified for use in active tooth movement or splinted together for orthodontic anchorage. This technique has an advantage over conventional fixed appliance orthodontic therapy because it can accomplish tooth movement concurrently with restorative and periodontal therapy. On occasion, minor tooth movement can be necessary to achieve the optimum occlusal scheme, crown form, and tooth position for the forces of occlusion to be displaced down the long axis of the periodontally compromised teeth. Once the occlusion, periodontal health, and crown contours for the provisional splinted restoration are acceptable, the final splinted restoration can be similarly fabricated, and it becomes an excellent orthodontic retainer.

• 한국산학기술학회논문지
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• 제16권2호
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• pp.1153-1163
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• 2015

본 연구는 수부손상환자를 대상으로 과제 지향적 활동이 손 기능에 미치는 효과를 알아보고자 하였다. 2011년 12월부터 2012년 10월까지 경남 창원에 위치하는 C병원에 내원한 16명의 수부손상환자를 두 그룹으로 무작위 할당한 후 실험군에 과제 지향적 활동을 1일 1회, 주 3회, 4주 동안 적용하고 그룹 간 비교를 실시하였다. 과제 지향적 활동군은 캐나다 작업수행측정(Canadian Occupational Performance Measure; COPM)을 통해 대상자가 선호하는 일상생활활동영역에 대한 과제를 제공하였다. 이때 중재의 효과를 검증하기 위해 손 기능 평가로 장악력 검사, 파악력 검사, 엄지의 맞섬, 손가락의 벌림 범위와, Purdue pegboard test, Disabilities of the Arm, Shoulder, and Hand(DASH)를 사용하였다. 중재 전후 비교에서 과제 지향적활동군은 모든 손 기능 평가에 유의하게 향상되었고(p<.05), 대조군의 손 기능도 유의하게 향상되었다(p<.05). 그룹 간 비교에서 과제 지향적 활동군은 손끝집기, 측면집기, 세점집기, Purdue pegboard test, DASH에서 대조군과 유의한 차이가 있었으나(p<.05), 장악력 검사와 엄지의 맞섬 및 손가락의 벌림 범위는 그룹 간 유의한 차이가 없었다. 본 연구의 결과를 통해 과제지향적 활동이 수부손상환자의 손 기능 향상에 더 효과적임을 알 수 있었다.

• 한국어류학회지
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• 제5권1호
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• pp.68-84
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• 1993

1989년, 1990년 12월 강원도 양양군 남대천에서 체포한 연어로부터 수정난을 받아 양양내수면연구소와 한국해양연구소 부화, 사육실에서 사육한 연어의 골격 발달과정을 조사하였다. 1. 부화직후 전장 1.95~2.13cm의 자어는 두부에 부설골, 주상악골, 치골, 주새개골의 일부가 골화되어 있다. 2. 자어의 골격중 섭이활동, 호흡에 관련된 턱, 아가미 등 내장골이 먼저 골화하며 대부분의 골격은 3~4cm에서 골화가 완료된다. 3. 턱니, 인두치, 서골치, 구개골위의 이빨은 전장 3~4cm에서 급격히 증가한다. 4. 꼬리지느러미는 부화직후 개체에 이미 17개의 줄기가 골화되어 있으며 지느러미 중에서 가장 빨리 완성된다.

• 대한소아치과학회지
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• 제30권3호
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• pp.477-482
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• 2003

하악과두부는 하악골에서 자주 발생하는 골절부위 중의 하나로 특히, 하악골의 성장이 완성되지 않은 소아의 경우 하악과두골절이 적절히 치료되지 않으면 안면 기형, 악관절 강직종, 부정교합, 그리고 하악골 발육이상 등을 초래할 수 있다. 소아에서의 하악과두골절의 치료목적은 동통없이 악기능을 정상적으로 회복시켜 악안면골의 성장발육을 정상적으로 유도하는 것이다. 치료방법의 선택은 환자의 나이, 골절된 위치, 골절부위의 이물질의 유무 등에 의해 이루어지나 소아의 경우 가능한 한 비수술적, 기능적 치료가 선호된다. 본 증례에서는 activator를 이용한 하악과두골절의 기능적 요법을 시행하고 골절부위의 기능적 재형성을 유도하면서 10개월간 관찰해 본 결과, 골절 부위의 동통 감소, 정상적 교합관계의 회복, 최대개구량의 증가, 하악의 편위 감소 등의 기능적 회복을 보였고 특이한 자각증상을 보이지 않았다. 소아에서 하악과두골절의 처치법으로 activtor를 이용한 기능적 치료는 동통없이 악기능을 회복시키고, 정상적인 교합관계로 유도할 수 있을 것으로 사료된다.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.81.2-82
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• 2003

Plants have evolved along with pathogens, and they have developed sophisticated defense systems against specific microorganisms to survive. G-protons are considered one of the upstream signaling components working as a key for the defense signal transduction pathway. For activation and inactivation of G-protein, GTP-biding proteins are involved. GTP -binding proteins are found in all organisms. Small GTP-binding proteins, having masses of 21 to 30kD, belong to a superfamily, often named the Ras supefamily because the founding members are encoded by human Ras genes initially discovered as cellular homologs of the viral ras oncogene. Members of this supefamily share several common structural features, including several guanine nucleotide binding domains and an effector binding domain. However, exhibiting a remarkable diversity in both structure and function. They are important molecular switches that cycle between the GDP-bound inactive form into the GTP-bound active form through GDP/GTP replacement. In addition, most GTP-binding proteins cycle between membrane-bound and cytosolic forms. such as the RAC family are cytosolic signal transduction proteins that often are involved in processing of extracellular stimuli. Plant RAC proteins are implicated in regulation of plant cell architecture secondary wall formation, meristem signaling, and defense against pathogens. But their molecular mechanisms and functions are not well known. We isolated a RacB homolog from rice to study its role of defense against pathogens. We introduced the constitutively active and the dominant negative forms of the GTP-hinging protein OsRacB into the wild type rice. The dominant negative foms are using two forms (full-sequence and specific RNA interference with RacB). Employing southern, and protein analysis, we examine to different things between the wild type and the transformed plant. And analyzing biolistic bombardment of onion epidermal cell with GFP-RacB fusion protein revealed association with the nucle.

• 통상정보연구
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• 제5권2호
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• pp.19-45
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• 2003

The main issues addressed in this paper are as follows : First, this paper makes a distinction among types of e-money, IC card type versus Network type, open-loop type versus closed-loop type, online type versus offline type and accountable type versus unaccountable type, and analysis the clear and accurate criterion. Second, generally speaking, e-money is a claim on originator of e-money and not legal tender, so, delivery of e-money by itself does not relieve of monetary obligation. Between it is not easy to define e-money, by now there are many definitions of e-money, there is a legal uncertainty accordingly and then it is not easy to find proper law applicable to resolve a particular issue. As a result. many problems relating to e-money would be solved through analogical application of the moot proper law among the laws that apply to the cash, check, credit card, or fund transfer after analyzing type of e-money at issue. This paper studies the methods on diffusion of the utilization of electronic money. To diffuse the usage of electronic money, it need; prerequisitely as a basic conditions independence of electronic money, non-reusability, and anonymity. And also as a additional conditions it need; usability in the offline commerce, transferability, divisibility. And now electronic money is used very actively, but still has many Jaw problems such as protections of consumer, law enforcement, supervisory, etc. So electronic money has called as money, but it is sure that electronic money is not a legal tender. So to facilitate the economic function of the electronic monel it is need to supplement the electronic money in the legal sides.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제32권1호
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• pp.16-22
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• 2010

Objective: Bisphosphonate related osteonecrosis of the jaw (BRONJ) is reported in patients taken bisphosphonate for a long time, however, the mechanism of osteonecrosis in BRONJ was not clarified yet. This study was designed to investigate the effect of short administraion zoledronate on the healing pattern of periosteum and sinus membrane after iliac bone graft into maxillary sinus. Methods: In this study, 18 Newzeland rabbits were used. The animals were divided into 2 group. In the experimental group, rabbits were treated with weekly peritoneal injection (0.06 mg/kg/week) of zoledronate for three times. In the control group, rabbits were treated with saline solution injection instead of zoledronate. Periosteum and sinus membrane were harvested from one rabbit of the experimental group and one of the control group in the fourth week. The autogeneous bone was harvested from ilium and grafted into maxillary sinus. The rabbits were sacrificed at 1, 2, 4 and 8 weeks after bone graft. The healing pattern of periosteum and sinus membrane were evaluated histologically. Results: Inflammatory reaction in the periosteum was less conspicuous and healing process appeared earlier in experimental group compared with control group at 1, 2, 4 weeks. There were no differences of microscopic findings of sinus membrane between both groups at any weeks. Conclusion: Short-term use of zoledronate decreased the inflammatory reaction and enhanced healing process in the periosteum. These findings suggest the possibility that zoledronte suppress the function of macrophages.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권1호
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• pp.41-48
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• 2020

Objectives: One of the most common complications of bilateral sagittal split ramus osteotomy (BSSRO) is neurosensory impairment of the inferior alveolar nerve (IAN). Accurate preoperative determination of the position of the IAN canal within the mandible using cone-beam computed tomography (CBCT) is recommended to prevent IAN dysfunction during BSSRO and facilitate neurosensory improvement after BSSRO. Materials and Methods: This randomized clinical trial consisted of 86 surgical sites in 43 patients (30 females and 13 males), including 21 cases (42 sides) and 22 controls (44 sides). Panoramic and lateral cephalographs were obtained from all patients. In the experimental group, CBCT was also performed from both sides of the ramus and mandibular body. Neurosensory function of the IAN was subjectively assessed using a 5-point scale preoperatively and 7 days, 1 month, 3 months, 6 months, and 12 months post-surgery. Data were analyzed using Fisher's test, Spearman's test, t-test, linear mixed-model regression, and repeated-measures ANCOVA (α=0.05, 0.01). Results: Mean sensory scores in the control group were 1.57, 2.61, 3.34, 3.73, and 4.20 over one year and were 1.69, 3.00, 3.60, 4.19, and 4.48 in the CBCT group. Significant effects were detected for CBCT intervention (P=0.002) and jaw side (P=0.003) but not for age (P=0.617) or displacement extent (P=0.122). Conclusion: Preoperative use of CBCT may help surgeons to practice more conservative surgery. Neurosensory deficits might heal faster on the right side.

• 대한치과보철학회지
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• 제56권1호
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• pp.50-55
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• 2018

무치악 환자에서 악간관계의 부조화는 자주 관찰되며, 의치에서 인공치의 교합접촉 시 안정의 결여는 환자의 불편감과 점막 외상, 나아가서는 근육과 신경의 변화나 감정적 장애를 일으킬 수 있다. 따라서 기능 시 의치에 가해지는 교합력을 고려하여 적절한 교합을 설정하는 것이 성공적인 의치 치료에 중요한 요소라고 할 수 있다. 본 증례에서는 하악 전돌로 인한 상하악 악궁간의 심한 부조화를 가진 완전무치악 환자를 양악총의치로 수복하였다. 비정상적인 악간 관계를 보상하기 위해 구치부 교차교합으로 인공치를 배열함으로써 의치의 안정과 유지를 확보하였고, 환자 또한 기능적, 심미적으로 만족하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제28권2호
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• pp.136-142
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• 2006

Temporomandibular joint(TMJ) disorders have characteristic clinical findings such as pain, joint sound, and abnormal jaw function. With the rapid progress in TMJ imaging techniques, magnetic resonance imaging(MRI) especially provides the clinician and researcher with the ability to evaluate TMJ disorders(effusion, anterior disk displacement) and the hard and soft tissue of the TMJ. In order to manage the internal derangement of TMJ such as anterior disk displacement, the so-called appliance therapy is commonly used. This technique became the treatment of choice before surgical intervention by many practitioners. The purpose of the present study was to evaluate and determine the efficacy of anterior repositioning splint by means of the change of the position of the disk through pre- and post-treatment MRI. MRI and clinical symptom were carefully recorded in TMJ disorder patients. The relationship between TMJ symptoms such as pain, clicking sound, and disk displacement and effusion in MRI were analyzed. Then, splint therapy was applied for 3 months according to our protocol; at day 1, patients should wear 24 hours, in order to accomodate the splint and then, wearing time is reduced to 12 hours per day for one month. During next 2 months, it is tapered to 8 hours per day according to the evaluation of the clinical symptoms. Post-treatment MRI was obtained after 3 month protocol. This treatment strategy improved the clinical symptoms of TMJ disorder, and effusion and articular disk position showed a significant change. In conclusion, a treatment modality using an anterior repositioning splint therapy is an appropriate method for temporomandibular disorder patients.