• Title/Summary/Keyword: JOL

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Factors related to the pros and cons of 'Jol-hon' of workers : the application of discriminant analysis (직장인의 '졸혼' 찬반 관련 요인 : 판별분석의 적용)

  • Lee, Chang-Seek;Jang, Ha-Young;Ryu, Eun-Kyung
    • Journal of Digital Convergence
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    • v.17 no.3
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    • pp.439-448
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    • 2019
  • The purpose of this study was to investigate factors affecting the pros and cons of 'Jol-hon' among workers. For this purpose, 288 workers were surveyed in Chungnam area. The main result are as follows. First, there were positively significant correlation among a hope, growth mindset, and organizational communication. Second, according to the discrimination analysis, the lower the age, the unmarried, the lower the hope, and the lower the organizational communication, the more favorable the 'Jol-hon'. In the case of married persons, there was no difference between the groups favoring and rejecting 'Jol-hon'. In the case of unmarried people, the lower the organizational communication, the more favorable the 'Jol-hon'. Finally, this study will present the theoretical basis for studying 'Jol-hon' in the future and suggest the policy implications to solve middle and senior couple problems.

Immune Responses of BALB/c Mice Administrated via Oral Route to a Combined Salmonella Typhimurium Ghost Vaccine (복합 살모넬라 타이피무리움 고스트 백신의 마우스 구강 투여에 의한 면역 응답)

  • Kim, Pan Gil;Ha, Yeon Jo;Lee, Su Man;Kim, Sam Woong;Gal, Sang Wan
    • Journal of Life Science
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    • v.25 no.11
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    • pp.1197-1203
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    • 2015
  • Salmonella Typhimurium (ST) JOL389 and χ3339 are strong virulent strains against mouse. ST χ8554 is derived by deletion of the asd gene from ST χ3339. Plasmid pMMP184 carrying a ghost cassette was transformed into ST χ8554, and ST χ8554 ghost cells were prepared and administrated via the oral route to BALB/c mice. Change in the amount of total IgG was not elicited to boosting of single ST χ8554 ghost cells, but the content was increased from 6 weeks after the 3rd administration. However, when the ST JOL389 ghost cells is administered together with ST χ8554 ghost cells, the content of total IgG was increased in 2 weeks post primary administration. It was found that the content of total IgG of the group mixed with ST JOL389 ghost cells showed an increased value of 8 times or more at 10 weeks when compared with the group of ST χ8554 ghost cells. The content of IgG1, IgG2a, and sIgA in both groups increased from 4 weeks postprimary administration. As a challenge test of virulent ST χ3339, χ8554 (pMMP184) and χ8554 (pMMP184)/JOL389 ghost cell groups showed protection of 50% or more when compared to the control group. These results suggest that the preparation of combined ghost cells from a strong virulent ST increases immunity more than a single strain.

Construction of a live attenuated Salmonella strain expressing FanC protein to prevent bovine enterotoxigenic Escherichia coli and evaluation of its immunogenicity in mice

  • Won, Gayeon;Kim, Hee Jung;Lee, John Hwa
    • Korean Journal of Veterinary Research
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    • v.57 no.1
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    • pp.9-15
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    • 2017
  • To construct a novel vaccine candidate against bovine enterotoxigenic Escherichia coli (ETEC), FanC, the major subunit of K99 fimbriae adhesion, was inserted into secretion plasmid pYA3560 containing a ${\beta}-lactamase$ secretion system. This was then transformed into ${\Delta}asd$ ${\Delta}crp$ Salmonella (S.) Typhimurium and designated as JOL950. Secretion of recombinant fanC fimbrial antigens was confirmed by immunoblot analysis. Groups of mice were inoculated with single or double doses of JOL950. Another group was used as a negative control. Compared to control mice, all immunized mice had significantly higher levels (p < 0.05) of serum immunoglobulin (Ig)G, and secretory IgA against FanC. The IgG2a and IgG1 titer assays revealed that immunization highly induced IgG2a compared to that of IgG1, indicating that T helper-1- related cell-mediated immune responses may be elicited by JOL950. The results show that both systemic and mucosal immunities against selected fimbrial antigens of bovine ETEC expressed by a live attenuated S. Typhimurium strain are prominently produced in mice immunized with JOL950 via an oral route.

Developmental Difference in Metacognitive Accuracy between High School Students and College Students (메타인지 정확성의 발달 차이 연구: 고등학생과 대학생 데이터)

  • Bae, Jinhee;Cho, Hye-Seung;Kim, Kyungil
    • Korean Journal of Cognitive Science
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    • v.26 no.1
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    • pp.53-67
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    • 2015
  • Metacognitive monitoring refers to high dimensional cognitive activities. Understanding one's own cognitive processes accurately can make effective controls for their performance. Brain area related with metacognition is PFC which is completed the order of late and it can be inferred that monitoring abilities is developing during late adolescent. In this study, we explored the developmental difference in monitoring accuracy between high school students and college students using by measuring JOL(Judgment of Learning). Participants was asked that they study Spanish-Korean word pairs and judge their future performance of memory. In the result, people in both groups thought that they could remember word pairs better than their actual performance. Absolute bias scores which mean the degree to predict their performance apart from true scores showed the interaction between subject groups and task difficulty. Specifically, people judged their learning state quite accurately in easy task condition. However, in difficult task condition, both groups showed inaccuracy for predicting their learning and the magnitude of the degree was bigger in the group of high school students.

A Study on the Constructional Intention and Aesthetic Consciousness in the Architecture of Tongdosa Jajang-temple (통도사(通度寺) 자장암(慈藏庵)의 건축에 내재된 조영의도(造營意圖)와 미의식(美意識)에 관한 연구)

  • Lee, Kweon-Yeong;Seo, Chi-Sang
    • Journal of architectural history
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    • v.11 no.4 s.32
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    • pp.117-128
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    • 2002
  • This paper aims at proposing constructional intention and aesthetic consciousness in the architecture of Jajang-temple, which was originally built by the great monk, Jajang in 7c. The results are as follows : 1) The layout and form of buildings in Jajang-temple were remarkably followed the situations and shapes of natural rocks related to Gumwa legend about the original establishment of the temple. 2) As natural rocks were penetrated into both the inner and outer space of buildings and so artificial skills were more or less restrained, it seems to be short of geometrical regularity, symmetry and formal integrity. 3) However it can be said that these architectural treatments were based on the aesthetic consciousness, so called In-Cha and Jol-Bak, which were conceived by intellectual elites in Chosun dynasty.

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Ghost Vaccine Prepared from Strong Virulent Salmonella typhimurium Does not Improve Immune Responses of BALB/c Mice (독력이 강한 S. typhimurium으로부터 유도된 고스트 백신으로 면역응답 개선에 관한 연구)

  • Ha, Yeon Jo;Kim, Tae Wan;Kim, Seung Tae;Gal, Sang Wan;Kim, Sam Woong
    • Journal of Life Science
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    • v.24 no.1
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    • pp.39-45
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    • 2014
  • Salmonella typhimurium MMP13 and S. typhimurium ${\chi}8554$ were derived from weak JOL401 and strong ${\chi}3339$ virulent strains. Heat-labile subunit B (LT-B) was used as an adjuvant to increase the effectiveness of the vaccine. Plasmid pMMP184 carrying a ghost cassette was transformed into MMP13 and ${\chi}8554$ to produce the ghost, and the prepared ghost cells were administered into the muscles of BALB/c mice. In the absence of the adjuvant, the total IgG content showed a tendency to increase contrary to the original virulent strength. In contrast, in the presence of the adjuvant, the strain that originated from the strong virulent showed a tendency to promote the immune more than that of weak virulent strain. However, the final concentration of total IgG was similar between the compared groups, indicating that the originated virulent strength does not affect a specific immune. Other elements of the immunoglobulins IgG1, IgG2a, and sIgAs did not show a specific trend. The results of Salmonella challenge showed a similar tendency to regardless of the originated virulence. Taken together, the results suggest that the Salmonella ghost cells promoted the immune system of BALB/c mice, irrespective of the virulence applied to create the ghost cells.

Home Economic View in Literatures and Documents of Cho-sun Dynasty (조선시대 문헌에 나타난 가족경제생활관)

  • 이길표
    • Journal of Families and Better Life
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    • v.13 no.4
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    • pp.115-124
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    • 1995
  • The purpose of this study was to accept its contents as lessons for today and to search for the correct way to lead home economy of the future by way of retranslating home economic view in literatures and documents of Cho-sun Dynasty(1392-1910) Through studying Cho-sun's literatures and documents: 「Ne-hun」 by the queen So He 「Kyou-dyoung-yo-ram」by Lee Whang 「Kyung-mong-yo-kul」by Lee Yul 「Song-ho-sa-sul」by Lee IK 「Sa-so-jol」by Lee Duk Moo「Buk-hak-ee」 by Park Je Ka 「Mok-min-sim-su」 by Jung Yak Yong. The results of this study can be summarized as follows : 1. The view of income: 1) Cut down on the too much greed of property (property income) 2) Work hard with diligence(earned income). 2. The view of expense : 1) Get food clothing and housing with frugality 2) Spend money for home rites and reception of guests with manner and truth without extravagnace. 3. The view of buying and selling: Buy and sell with credit. 4. The view of borrowing and lending: Borrow and lend money honestly,. 5. The view of home book-keeping : Keep home book-keeping every day. 6. The view of economic preparation : Save for a rainy day wisely.

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Modeling of Health-Promoting School - Based on Health Center of University - (건강증진학교 모형개발 - 대형 보건소 활동을 중심으로 -)

  • Ha, Eunhee;Jol, Heuisug;Yun, Youngok;Kang, Myunggeun
    • Journal of the Korean Society of School Health
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    • v.14 no.1
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    • pp.83-93
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    • 2001
  • Objectives: The purpose of this study is to develop a health-promoting program centered on the university-health center and to provide a developed program for students and faculties. Methods: A survey was conducted of 719 female students and 238 faculties concerning their health-promoting programs. Based on the results of the survey, we developed programs that could be applied to students and faculties. After operating the programs, we developed further models by evaluating the effectiveness and satisfaction. Conclusions: We selected a comprehensive health-promoting program that included weight control, preventive inoculation, sex education and control of disease based on repsective needs. We also applied programs developed through collaboration with other departments from September 1998 to August, 1999. Users of the preventive inoculation-program increased by one point five during the year. Also, participants were generally satisfied with the weight control program and succeeded in reducing weight. We hope that we can set up this program and expand it by developing various other projects in Korea.

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Hens immunized with live attenuated Salmonella strains expressing virulence-associated genes in avian pathogenic Escherichia coli passively transfer maternal antibodies to chicks

  • Won, Gayeon;Lee, John Hwa
    • Korean Journal of Veterinary Research
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    • v.56 no.3
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    • pp.167-176
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    • 2016
  • We investigated whether maternal antibodies (mAbs) elicited by dams immunized with recombinant vaccine candidates against avian pathogenic Escherichia coli (APEC) can passively confer protective immunity to chicks. In the present study, pBP244 plasmids carrying selected antigens of APEC were transformed into Salmonella Typhimurium JOL912, which was used as a vaccine candidate against APEC. The hens were immunized with the vaccine candidates using prime or booster doses. The levels of IgG and sIgA specific to the selected antigens increased significantly following prime immunization. To evaluate the persistence of passively transferred mAbs, the levels of IgY and IgA were determined in egg yolks and whites, respectively. The eggs from the immunized group showed consistently increased levels of IgY and IgA until week 16 post-laying (PL) and week 8 PL, respectively, relative to the control group. The presence of mAbs was observed in chicks that hatched from the hens, and titers of plasma IgY were consistently raised in those from the immunized hens by day 14 post-hatching. Further, chicks from the immunized hens were protected from challenge with a virulent APEC strain, whereas those from non-immunized hens showed acute mortality.

The fucose containing polymer (FCP) rich fraction of Ascophyllum nodosum (L.) Le Jol. protects Caenorhabditis elegans against Pseudomonas aeruginosa by triggering innate immune signaling pathways and suppression of pathogen virulence factors

  • Kandasamy, Saveetha;Khan, Wajahatullah;Kulshreshtha, Garima;Evans, Franklin;Critchley, Alan T.;Fitton, J.H.;Stringer, Damien N.;Gardiner, Vicki-Anne;Prithiviraj, Balakrishnan
    • ALGAE
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    • v.30 no.2
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    • pp.147-161
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    • 2015
  • Brown algal extracts have long been used as feed supplements to promote health of farm animals. Here, we show new molecular insights in to the mechanism of action of a fucose containing polymer (FCP) rich fraction from the brown seaweed Ascophyllum nodosum using the Caenorhabditis elegans-Pseudomonas aeruginosa PA14 infection model. FCP enhanced survival of C. elegans against pathogen stress, correlated with up-regulation of key immune response genes such as: lipases, lysozyme (lys-1), saponin-like protein (spp-1), thaumatin-like protein (tlp-1), matridin SK domain protein (msk-1), antibacterial protein (abf-1), and lectin family protein (lfp). Further, FCP caused down regulation of P. aeruginosa quorum sensing genes: (lasI, lasR, rhlI, and rhlR), secreted virulence factors (lipase, proteases, and elastases) and toxic metabolites (pyocyanin, hydrogen cyanide, and siderophore). Biofilm formation and motility of pathogenic bacteria were also greatly attenuated when the culture media were treated with FCP. Interestingly, FCP failed to mitigate the pathogen stress in skn-1, daf-2, and pmk-1 mutants of C. elegans. This indicated that, FCP treatment acted on the regulation of fundamental innate immune pathways, which are conserved across the majority of organisms including humans. This study suggests the possible use of FCP, a seaweed component, as a functional food source for healthy living.