• Bulletin of the Korean Chemical Society
• /
• 제35권1호
• /
• pp.273-276
• /
• 2014

• 미생물학회지
• /
• 제16권1호
• /
• pp.11-15
• /
• 1978

Glucose and galactose were the inhibitors of pigmentation of Serrratia marcescens. Other sugars, however, even the fructose which is the structural isomer of glucose and galactose did not affect to pigmentatioin. The yield of pigmentation was descreased when the glucose was added to culture medium. And it was known to that the antibiotics was roled as the inhibitors of pigmentation. The limit concentration of the inhibitors were as followings :rifampicin, $1{\mu}g/ml$. Addition of rifampicin$(1{\mu}g/ml)$ at 6 hrs cultures inhibited the formation of pigment completely.

• 대한화학회지
• /
• 제21권3호
• /
• pp.161-170
• /
• 1977

Glycine (또는 glycino 음이온)과 styrene을 리간드로 하는 백금(II) 착물이 합성되었다. 적외선 분광법에 의하면 N-트란스 이성체에서는 킬레이트를 이루는 glycine음이온의 질소원자가 styrene에 대하여 트란스 위치에 있음이 확인되었다.

• 한국작물학회:학술대회논문집
• /
• 한국작물학회 2004년도 춘계 학술대회지
• /
• pp.122-123
• /
• 2004

• Bulletin of the Korean Chemical Society
• /
• 제16권1호
• /
• pp.12-16
• /
• 1995

The diastereoselectivity of addition reaction of crotylmetal reagents to cobalt-complexed acetylenic aldehydes and metal-free aldehydes was examined. The anti-diastereomer was the predominant product when the crotyl metallics were Cr, Sn, and Zr. In THF, the uncomplexed aldehydes normally gave higher anti-diastereoselectivity. However, the cobalt-complex of silicon-substituted propynals with three bulky substituents produced increased proportions of syn-diastereomer. In DMF, the selectivity shifted towards syn-isomer except in the case of dimethylphenylsilyl substituent. When tributylstannane was used in the presence of BF3 etherate, moderate syn- selectivity was observed with uncomplexed aldehydes, but only decomposed products from complexed aldehydes.

• Bulletin of the Korean Chemical Society
• /
• 제1권1호
• /
• pp.23-26
• /
• 1980

Direct photoisomerizations of benzalpyrrolinones yield the corresponding E-isomers via a singlet state, since no effect of oxygen on the reaction rates was observed. The Z-oxodipyrromethene was photoisomerized to the E-isomer in a degassed system. In an aerobic system the oxodipyrromethene 3 was photoisomerized at the early stage of the reaction and photooxygenated slowly at latter stage of the reaction. For bilirubin, other (possibly Z ${\to}$ E) than self-sensitizing $^1O_2$ reaction should have occurred because of the lack of a solvent effect on the self-sensitized photooxidation reaction rate at the early stage.

• Bulletin of the Korean Chemical Society
• /
• 제9권4호
• /
• pp.195-198
• /
• 1988

(-)-(1R, 2R) and (+)-(1S, 2S)-menthyl-trans-2-phenylcyclopropanecarboxylat e have been synthesized with the aid of chiral Cu(II) complex catalyst by the addition reaction of l-menthyldiazoacetate to styrene. The yield was 75%, with the purity of trans isomer over 95% and the optical purity of 95%.

• 대한약학회:학술대회논문집
• /
• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
• /
• pp.390.2-390.2
• /
• 2002

The fruits of cardamon (family Zingiberaceae) are used in traditional medicine for the treatment of several ailments. such as stomach disorders, liver abscess, and infection of the throat, and as a common spice as well, Amomum tsao-ko Crevost et Lemarie. a Zingiberaceous plant called "초과" in korea, is an oriental folk medicinal herb for the treatment of stomach illness. The present paper reports the isolation of the constituents of the fruits of this plant and their antifungal activity. (omitted)

• Archives of Pharmacal Research
• /
• 제10권1호
• /
• pp.50-59
• /
• 1987

(E)-2-Phenylcyclopropylamine ((E)-TCP), (Z)-2-Phenylacyclopropylamine ((Z)-TCP), (E)-1-methyl-2-phenylcyclopropylamine ((E)-MTCP), and (Z)-1-methyl-2-phenylcyclopropylamine ((Z)-MTCP) were synthesized and used to determine to what extent 1-methylsubstitution and stereochemistry of 2-phenycyclopropylamines affect inhibition of monoamine oxidase (MAO). Inhibition of rat brain mitochondrial MAO-A and B by the compounds were measured using serotonin and benzylamine as the substrate, respectively and $IC_{50}$ values obtianed with 95% confidence limits by the method of computation. For the inhibition of MAO-A, (E)-MTPC ($IC_{50}$ = 6.2 * $10^{-8}$M) was found to be 37 times more potent than (Z)-MTCP ($IC_{50}$ = 7.8 * $10^{-8}$M), was 7 times more potent than (Z)-MTCP($IC_{50}$= 4.7 * $10^{-7}$M) and (E)-TCP($IC_{50}$ =7.8 * $10^{-8}$M),0.6 times as potent as (Z)- TCP ($IC_{50}$ = 4.4 * $10^{-8}$M). The results suggested that while without 1-methyl group, potency of a (Z)-isomer was comparable to that of (E)-isomer, the methyl group in its (Z)-position was very unfavorable to the inhibition of MAO and that in its (E)-position, the methyl group contributed positively to the potency as found by the fact that (E)-MTCP was 1-5 times more potent than (E)-TCP. In view of the selective inhibition of MAO-A- or B over MAO-A and 1-methyl substitution as well as the stereochemical factors did not significantly influence the selectivity.

• 공업화학
• /
• 제20권3호
• /
• pp.335-338
• /
• 2009

유기발광다이오드의 청색 발광 물질로 많은 관심을 받고 있는 디스티릴아릴렌 화합물들의 합성 과정에서 핵심적인 중간체인 브로모트리페닐에틸렌 화합물들은 브로모벤조페논과 벤질포스포네이트의 반응을 통하여 얻어진다. 이 반응은 분리하기 어려운 (Z)-와 (E)-기하이성질체가 60 : 40의 비율로 생성한다. 본 연구에서는 2-프로탄올을 이용한 재결정법을 통하여 (Z)-이성질체를 간단하게 분리하였다. X-ray를 이용하여 (Z)-이성질체의 결정 구조를 살펴본 결과, tert-부틸페닐 고리와 브로모페닐 고리 간의 dihedral angle은 $56.5(4)^{\circ}$이며 브로모페닐 고리와 페닐 고리 간의 dihedral angle은 $74.1(4)^{\circ}$였다.