• Title/Summary/Keyword: Iridium-192

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The Clinical Application of Radioactive Iridium (Ir-192) Brachytherapy (방사선 이리디움(Ir-192) 근접치료의 임상적 응용)

  • Yoo, Seong-Yul
    • The Journal of Korean Society for Radiation Therapy
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    • v.3 no.1
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    • pp.11-18
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    • 1989
  • Brachytherapy is known to be a good modality to achieve local control as a boost treatment following limited external irradiation, which may reduce the external beam related complication particularly in head and neck cancer. The authors developed iridium-192 ribbons recently to replace the radium needles in the field of brachytherapy. Total of 48 cases of head and neck and pelvic-perineal cancer patients had been treated with Ir-192 ribbons during last two years from October 1986 to September 1988, and the results were analyzed to assess the applicability of the fabricated sources. The conclusion is as follows; 1. Iridium implant resulted excellent tumor control effect in clinical application. 2. Iridium is superior than radium and cecium in brachytherapy because of easier to use and lesser exposure to the personnel. 3. Afterloading technique is useful to modify dose distribution, to expand treatment site and method, and to develop interstitial hyperthermia.

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The Effect of Iridium-192 Implant in the Treatment of Head and Neck Cancer (두경부암에서 방사성이리디움 삽입치료의 효과)

  • Yoo Seong-Yul;Koh Kyoung-Hwan;Cho Chul-Koo
    • Korean Journal of Head & Neck Oncology
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    • v.4 no.1
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    • pp.13-19
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    • 1988
  • Brachytherapy is known to be a good modality to achieve local control as a boost treatment following limited external irradiation, which may reduce the external beam related acute radiation sickness, particularly in head and neck cancer. The authors developed iridium-192 ribbons recently to replace the radium needles. Total of 13 head and neck cancer patients had been treated with Ir-192 ribbons during last one year from October 1986 to September 1987, and the results were analysed to assess the applicability of the fabricated sources. The conclusion is as follows; 1) Iridium implant achieved 54% (7/13) of complete response and 69% (9/13) of overall response rate in head and neck cancer. 2) Iridium is superior to radium and cecium in brachytherapy because of easier to use and lesser exposure to the personnel. 3) Afterloading technique is useful to modify dose distribution, to expand treatment site and method, and to develop interstitial hyperthermia.

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Spectrophotometric Determination of Iridium After Extraction of the Stannous-Chloro Complex by High Molecular Weight Amine (고분자량 아민에 의한 이리듐 제1염화주석 착물에 추출 및 분광광도법에 의한 이리듐의 정량법)

  • Kang Hyung Kun;Koo Soon Chung
    • Journal of the Korean Chemical Society
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    • v.19 no.5
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    • pp.343-350
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    • 1975
  • About 20${\sim}$100${\mu}g$ iridium have been extracted quantitatively as stannous-chloro Complex from aqueous solution by Alamine-336, a high molecular weight tertiary amine, dissolved in benzene. The extractability was confirmed by radioactive tracer of iridium-192. The spectrophotometric measurements of the extracted species at 322.5 nm indicate the feasibility of this method to be used as an analytical procedure for the determination of micro amount of iridium. An anion model of stannous-chloro complex of iridium has been postulated to account for the extraction mechanism.

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A Study on the Evaluation of Radiation Safety in Opened-Ceiling-Facilities for Radiography Testing (천장 개방형 RT 사용시설의 방사선 안전성 평가 연구)

  • Sung-Hoe, Heo;Won-Seok, Park;Seung-Uk, Heo;Byung-In, Min
    • Journal of the Korean Society of Radiology
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    • v.16 no.6
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    • pp.741-749
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    • 2022
  • Radiography-Testing that verify the quality of welding structures without destruction are overwhelmingly used in industries, but many safety precautions are required as radiation is used. The workers for Radiography-Testing perform the inspection by moving the Iridium-192 radiation source embedded in the transport container of the gamma-ray irradiator within or outside the facility. The general facility is completely blocked about radiation from the outside with thick concrete, but if it is difficult for worker to handle object of inspection, facilities ceiling can be opened. A general facility may be constructed using a theoretical dose evaluation method because all exterior facilities are blocked, but if the ceiling is open, it is not appropriate to evaluate radiation safety with a simple theoretical calculation method due to the skyshine effect. Therefore, in this study, the radiation safety of the facility was evaluated in the actual field through an ion chamber survey-meter and an accumulated dose-meter called as OSLD, and the actual evaluation environment was modeled and evaluated using the Monte Carlo simulation code as FLUKA. According to the direction of the irradiation, the radiation dose at the facility boundary was difficult to meet the standards set by the regulatory authority, and radiation safety could be secured through additional methods. In addition, it was confirmed that the simulation results using the Iridium-192 source were valid evaluation with the actual measured results.

Evaluation of Absorbed Dose for the Right Lung and Surrounding Organs of the Computational Human Phantom in Brachytherapy by Monte Carlo Simulation (근접방사선치료 시 몬테카를로 전산모사를 이용한 인체전산팬텀의 우측 폐와 주변 장기 선량평가)

  • Lee, Jun-Seong;Kim, Yang-Soo;Kim, Min-Gul;Kim, Jung-Soo;Lee, Sun-Young
    • Journal of radiological science and technology
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    • v.43 no.6
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    • pp.443-451
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    • 2020
  • This study is to evaluate absorbed dose from right lung for brachytherapy and to estimate the effects of tissue heterogeneities on dose distribution for Iridium-192 source using Monte Carlo simulation. The study employed Geant4 code as Monte Carlo simulation to calculate the dosimetry parameters. The dose distribution of Iridium-192 source in solid water equivalent phantom including aluminium plate or steel plate inserted was calculated and compared with the measured dose by the ion chamber at various distances. And the simulation was used to evaluate the dose of gamma radiation absorbed in the lung organ and other organs around it. The dose distribution embedded in right lung was calculated due to the presence of heart, thymus, spine, stomach as well as left lung. The geometry of the human body was made up of adult male MIRD type of the computational human phantom. The dosimetric characteristics obtained for aluminium plate inserted were in good agreement with experimental results within 4%. The simulation results of steel plate inserted agreed well with a maximum difference 2.75%. Target organ considered to receive a dose of 100%, the surrounding organs were left the left lung of 3.93%, heart of 10.04%, thymus of 11.19%, spine of 12.64% and stomach of 0.95%. When the statistical error is performed for the computational human phantom, the statistical error of value is under 1%.

Microscopic Examination of Fracture Particles on the Surface of Ir-192 Sealed Source and Ultrasonic Cleaning (Ir-192 밀봉선원의 표면오염 방지)

  • Kuk, Il Hiun;Park, Chun Deuk;Koo, Ja Ho
    • Journal of Radiation Industry
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    • v.9 no.2
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    • pp.91-102
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    • 2015
  • The iridium disc, generally used in industrial radiography, is examined to find the fracture morphology and fine particles remaining on the shear blank surface. Randomly selected 1,200 discs were observed under a scanning electron microscope tilted more than $45^{\circ}$. Fracture surfaces are classified into three groups: (1) surface fall-out, (2) fracture on the edge and (3) multi-step brittle fracture, which shows the mutual relationship between the fracture morphology and remaining particles. Fracture particles were removed by cleaning the discs in a ultrasonic bath with acetone and collected at the bottom. Removed number of the particles were counted for each different group of fracture surfaces. Followings are conclusions: (1) About 80.5% of discs (966/1,200), have sound plastic shear surfaces with particles remained. (2) About 2% discs accompany surface fall-out's having large particles tens of ${\mu}m$, which is stable not to be pulled out even after the considerably long time of ultrasonic cleaning. (3) About 5% discs contain the fractures on the edge and the particles are removed thoroughly within 30 minutes. (4) 234 discs out of 1,200 discs have multi-step fracture surfaces whose particles never removed in a short period of time but come out very slowly. Such a disc having multiple-step fracture is attributed to the promate cause to the 'leaker'. It is noted here that the discs having mutiple-step fractures should be treated separately with special care, and it is need to study how to treat them.

Comparison of Non-Destructive Testing Images using $^{192}Ir$ and $^{75}Se$ with Computed Radiography System (Computed Radiography 시스템에 $^{192}Ir$$^{75}Se$ 동위원소를 적용하여 촬영한 비파괴검사 영상 비교)

  • Kang, Sang-Mook;Chol, Chang-Il;Lee, Seung-Kyu;Park, Sang-Ki;Kim, Yong-Kyun
    • Journal of Radiation Protection and Research
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    • v.35 no.1
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    • pp.26-33
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    • 2010
  • A computed Radiography (CR) system by use of reusable Image Plate (IP) offers a convenient and reliable way to replace a conventional film-screen system for NDT (non-destructive testing) field. The quality of a radiography to detect a defect of welded objects depends on the procedure embracing several factors such as measurement conditions, image plate type/class, radiation energy, radiation type, and source to image plate distance. Also, the ability of images to detect a flaw reduces with increasing object thickness. In the study, the properties of gamma ray source were summarized for NDT field and inspection images of CR image system manufactured by FUJI were acquired using $^{75}Se$ and $^{192}Ir$ with welded objects. We analyzed the gray scale of hole defect image by using XCAP image processing program and calculated the image contrast and SNR in definition. Also the sesitivities of image quality indicator(IQI) were calculated for hot and cooling tube image of $^{75}Se$ and $^{192}Ir$.

A Study on the Sediment Transport using Radioisotope Tracer (방사성동위원소 추적자를 이용한 표사이동 추적실험)

  • Choi Byung-Jong;Jung Sung-Hee;Kim Jong-Bum;Lee Jong-Sup
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.16 no.3
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    • pp.162-170
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    • 2004
  • On the basis of the radiotracer technology and the related equipments which have been developed for its industrial application through the nuclear long-term research project, a radiotracer study on sediment transport was carried out as a part of the development of the radiotracer technology for a coastal environment. The crystalline material doped with iridium having a similar composition and specific gravity as those of the bedload sand collected from the research area was produced by the oxide-route method. A radioisotope container was specially designed to inject the radiotracer from 1 m above the sea bedload without radioactive contamination during the transport from the nuclear reactor at KAERI. The position data from the DGPS and the radiation measurement data were collected concurrently and stored by means of the application software programmed with the LabVIEW of the National Instrument. The position data was reprocessed to represent the real position of the radiation probe under water and not that of the DGPS antenna on board. The time dependency of the spatial distribution of the sediment was studied in the area through three tracking measurements after the iridium glass was injected. This trial application showed the potential of the radiotracer technology as an important role for maintaining and developing the coastal environment in the future.

Dose modeling and its Application of Ir-192 for substitution of Ralstron Brachytherapy source (Ralstron 선원대체형 Iridium-192 선원의 선량모델링과 응용)

  • 김옥배;최태진;김진희;이호준;박정호;김성규;조운갑;한현수
    • Progress in Medical Physics
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    • v.11 no.2
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    • pp.131-139
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    • 2000
  • We designed high dose rate Ir-192 source which was prepared for substitute the Co-60 source in Ralstron unit (Simatsu, Japan) which is supplied for cervical cancer treatment. The source dimension is 1.5 mm in a diameter and 1.5mm thickness of cylinder and encapsulated with 3 mm diameter of stainless steel(SUS316L) to substituted for the Co-60 source size. The Ir-192 source was prepared the dose model for tissue dose computation through the experimental determination of apparent activity and applied the empirical tissue correction factors extended to 20cm distance. The tissue dose model was applied the 4.69 R/cm-mCi-hr gamma constant and the ratio of energy absorption coefficient of water to that of air showed 1.112 include filteration of the self-absorptions. In this experiments, we prepared the dose computation software to clinical usefulness.

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Determination of Exposure Dose Rate and Isotropic Distributions of Substitute High Dose Rate Ir-192 Source for Co-60 Brachytherapy Source (원격강내조사용 Co-60 선원의 대체용 Ir-192 선원의 조사선량결정 및 선량 등방성조사)

  • 최태진;원철호;김옥배;김시운;김금배;조운갑;한현수;박경배
    • Progress in Medical Physics
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    • v.9 no.1
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    • pp.55-64
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    • 1998
  • In recent, the demand of development of the high dose rate brachytherapy source increased for substitute for Co-60 source by iridium source, since the supplying Co-60 source is very depressed and the high dose rate brachytherapy sources are entirely imported from the abroad. This study investigated the exposure rates and isotropic dose distributions for the Ir-192 source produced from $\^$191/Ir(n,r)$\^$192/Ir by nuclear reactor in Korea Atomic Energy Research Institute. The activity of source was obtained an 1.012 Ci (the initial activity without encapsulation was 2,87Ci) by measurement with encapsuled stainless steel. The exposure rate of provided Ir-192 source was determined on 6.36 ${\pm}$ 0.147 Rm$^2$/h-GBq (2.350 ${\pm}$ 0.054 Rcm$^2$/mCi-hr) within ${\pm}$ 2.2% discrepancy with IC-10 ion chamber (0.14 cc) which was mounted on the acrylic jig to 5, 10 and 20 cm from the center of source. The calculated doses with 22 most significant spectrum lines were corrected with intrinsic efficiency of the germanium detector were compared to measured exposure dose rates within ${\pm}$3.8 % discrepancy. The authors confirmed the high dose rate Ir-192 source could be replaced the long decayed Co-60 source via investigation of the isotropic dose distributions in lateral, source axis and diagonal direction of source center are very closed to within 3% uncertainties. Especially, this exposure rate constant and isotropic dose distribution will be fundamental to build the high dose rate source and develop the computed therapy planning system.

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