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Vital Sign Detection in a Noisy Environment by Undesirable Micro-Motion (원하지 않는 작은 동작에 의한 잡음 환경 내 생체신호 탐지 기법)

  • Choi, In-Oh;Kim, Min;Choi, Jea-Ho;Park, Jeong-Ki;Kim, Kyung-Tae
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.30 no.5
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    • pp.418-426
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    • 2019
  • Recently, many studies on vital sign detection using a radar sensor related to Internet of Things(IoT) smart home systems have been conducted. Because vital signs such as respiration and cardiac rates generally cause micro-motions in the chest or back, the phase of the received echo signal from a target fluctuates according to the micro-motion. Therefore, vital signs are usually detected via spectral analysis of the phase. However, the probability of false alarms in cardiac rate detection increases as a result of various problems in the measurement environment, such as very weak phase fluctuations caused by the cardiac rate. Therefore, this study analyzes the difficulties of vital sign detection and proposes an efficient vital sign detection algorithm consisting of four main stages: 1) phase decomposition, 2) phase differentiation and filtering, 3) vital sign detection, and 4) reduction of the probability of false alarm. Experimental results using impulse-radio ultra-wideband radar show that the proposed algorithm is very efficient in terms of computation and accuracy.

Superhongmi bran extract improves lipid profile and menopause symptoms: a randomized, placebo-controlled clinical trial (슈퍼홍미 미강 추출물의 폐경 후 여성의 혈중 지질 농도 및 대사성 질환 개선 효과)

  • Chung, Soo Im;Nam, Su Jin;Liang, Jie;Ma, Jing Wen;Kang, Mi Young
    • Korean Journal of Food Science and Technology
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    • v.51 no.2
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    • pp.182-187
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    • 2019
  • Women who undergo natural menopause transition have increased numbers of risk factors relating to metabolic syndrome due to estrogen deficiency. This study was conducted to investigate the effect of Superhongmi bran extract on metabolic syndrome improvement in menopausal women. Thirty women, who participated in a randomized, double-blind, placebo-controlled trial, were assigned to placebo-control (n=15) or Superhongmi bran extract (n=15) groups and were asked to consume two tablets (350 mg per extract per tablet) per day. After 12 weeks, weight, body mass index (BMI), plasma triglyceride (TG) levels, and total cholesterol (TC) levels were significantly decreased, whereas HDL-cholesterol (HDL-C), apolipoprotein A1 (ApoA1), adiponectin, superoxide dismutase 1 (SOD1), and GSH (glutathione) concentrations were significantly increased in the Superhongmi bran extract group. Moreover, $17{\beta}-estradiol$, and progesterone levels in the Superhongmi group were significantly higher than those in the placebo-control group. These results suggest that Superhongmi bran extract alleviates metabolic symptom in menopausal women.

A Textile Analysis of Woolen Carpet Excavated from Seongjeonggak Hall, in Changdeokgung Palace (창덕궁 성정각 출토 모담(毛毯) 직물 분석)

  • Pak, Seonghee;Lee, Ryangmi;An, Boyeon;Cho, Misook
    • Journal of Conservation Science
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    • v.37 no.2
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    • pp.120-134
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    • 2021
  • A Woolen carpet from the late Joseon Dynasty was unearthed in the process of repairing Seongjeonggak in Changdeokgung. Since relics are rarer than documentary records, the woolen carpet is highly valued as a relics. It is presumed to have been woven in the late 19th or early 20th century because there is a record of repairing Seongjeonggak in 1907. In the carpet, a pattern is made by inserting colored yarn dyed yellow and red onto a reddish-purple ground weave. The selvage of the woolen carpet used cotton thread, and jute is used for the warp and weft of the ground weave. The colored patterns is made of wool in the form of loop pile. Cut piles may appear occasionally when the colored yarn changes, but are almost invisible from the surface because they are pressed tightly with a shuttered weft. Making carpets with jute and wool is thought to be influenced by the Brussels carpets of the mid-18th century. Furthermore, the woolen carpet is torn and the pattern is completely unclear; however, it is understandable that the pattern is partially repeated. Microscopic and Fourier transform-Infrared spectrometer(FT-IR) analyses were performed for the above investigation. To identify the dyes used in relics, we compared them with natural dyed fabric samples based on chromaticity measurements and Ultraviolet/Visible spectrophotometer(UV-Vis) analysis. These analyses revealed that the woolen carpet's dyed green yarn did not use indigo, and reddish-purple ground weave is estimated to have used Caesalpinia sappan.

Improvement of blood glucose homeostasis in mice fed with Capsosiphon fulvescens extract-added whole wheat cookie (매생이 추출물 첨가 통밀 쿠키의 마우스 혈당 항상성 개선 효과)

  • Lim, Jae-Min;Chun, Su-Hyun;Jeong, Yu-Jin;Lee, Kwang-Won
    • Korean Journal of Food Science and Technology
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    • v.53 no.3
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    • pp.313-320
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    • 2021
  • The present study aimed to investigate the effect of whole wheat cookie supplemented with Capsosiphon fulvescens (CF) extract on serum glucose homeostasis in C57BL/6 mice. This study examined whether the same effect was demonstrated for whole wheat cookie in comparison to previous research documenting the glucose-lowering effect of food products combined with CF extract. Mice were divided into three groups depending on the diet administered: normal cookie (NC), whole wheat cookie (WC), and WC blended with CF extract (WCFE). After 4 weeks of administering the experimental diet, the blood glucose level, serum insulin level, and homeostatic model assessment for insulin resistance index were found to be significantly lower in the WCFE group than in the NC and WC groups. These results suggest that whole wheat cookie containing CF extract is effective in preventing insulin resistance and maintaining blood glucose homeostasis.

Preparation and Release Properties of Acetaminophen Imprinted Functional Starch based Biomaterials for Transdermal Drug Delivery (경피약물전달을 위한 아세트아미노펜 각인 기능성 전분 기반 바이오 소재 제조 및 방출 특성)

  • Kim, Han-Seong;Kim, Kyeong-Jung;Lee, Si-Yeon;Cho, Eun-Bi;Kang, Hyun-Wook;Yoon, Soon-Do
    • Applied Chemistry for Engineering
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    • v.32 no.3
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    • pp.299-304
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    • 2021
  • This study focuses on the preparation of acetaminophen (AP) imprinted functional biomaterials for a transdermal drug delivery using mung bean starch (MBS), polyvinyl alcohol (PVA), sodium benzoate (S) as a crosslinking agent, glycerol (GL) as a plasticizer, and melanin (MEL) as a photothermal agent. The prepared AP imprinted biomaterials were characterized using FE-SEM and their physical properties were evaluated. The photothermal effect and AP release property for functional biomaterials were examined with the irradiation of near infrared (NIR) laser (1.5 W/cm2). When the NIR laser was irradiated on functional biomaterials with/without the addition of MEL, the temperature of MEL added biomaterial increased from 25 ℃ to 41 ℃, whereas the biomaterial without MEL increased from 25 ℃ to 28 ℃. Results indicate that there is the photothermal effect of prepared biomaterial with the addition of MEL. Based on the results, AP release properties were evaluated using standard buffer solutions and artificial skin. It was found that AP release rates of MEL added AP loaded biomaterials were 1.2 times faster than those of MEL non-added AP loaded biomaterials when irradiating with NIR laser. We envision that the developed functional biomaterials can be utilized for an acute pain-killing treatment.

Measurement of Sulfur Dioxide Concentration Using Wavelength Modulation Spectroscopy With Optical Multi-Absorption Signals at 7.6 µm Wavelength Region (7.6 µm 파장 영역의 다중 광 흡수 신호 파장 변조 분광법을 이용한 이산화황 농도 측정)

  • Song, Aran;Jeong, Nakwon;Bae, Sungwoo;Hwang, Jungho;Lee, Changyeop;Kim, Daehae
    • Clean Technology
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    • v.26 no.4
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    • pp.293-303
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    • 2020
  • According to the World Health Organization (WHO), air pollution is a typical health hazard, resulting in about 7 million premature deaths each year. Sulfur dioxide (SO2) is one of the major air pollutants, and the combustion process with sulfur-containing fuels generates it. Measuring SO2 generation in large combustion environments in real time and optimizing reduction facilities based on measured values are necessary to reduce the compound's presence. This paper describes the concentration measurement for SO2, a particulate matter precursor, using a wavelength modulation spectroscopy (WMS) of tunable diode laser absorption spectroscopy (TDLAS). This study employed a quantum cascade laser operating at 7.6 ㎛ as a light source. It demonstrated concentration measurement possibility using 64 multi-absorption lines between 7623.7 and 7626.0 nm. The experiments were conducted in a multi-pass cell with a total path length of 28 and 76 m at 1 atm, 296 K. The SO2 concentration was tested in two types: high concentration (1000 to 5000 ppm) and low concentration (10 ppm or less). Additionally, the effect of H2O interference in the atmosphere on the measurement of SO2 was confirmed by N2 purging the laser's path. The detection limit for SO2 was 3 ppm, and results were compared with the electronic chemical sensor and nondispersive infrared (NDIR) sensor.

Verification of GEO-KOMPSAT-2A AMI Radiometric Calibration Parameters Using an Evaluation Tool (분석툴을 이용한 천리안2A 기상탑재체 복사 보정 파라미터 검증)

  • Jin, Kyoungwook;Park, Jin-Hyung
    • Korean Journal of Remote Sensing
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    • v.36 no.6_1
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    • pp.1323-1337
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    • 2020
  • GEO-KOMPSAT-2A AMI (Advanced Meteorological Imager) radiometric calibration evaluation is an essential element not only for functional and performance verification of the payload but for the quality of the sensor data. AMI instrument consists of six reflective channels and ten thermal infrared ones. One of the key parameters representing radiometric properties of the sensor is a SNR (Signal-to-Noise Ratio) for the reflective channels and a NEdT (Noise Equivalent delta Temperature) for the IR ones respectively. Other important radiometric calibration parameters are a dynamic range and a gain value related with the responsivity of detectors. To verify major radiometric calibration performance of AMI, an offline radiometric evaluation tool was developed separately with a real-time AMI data processing system. Using the evaluation tool, validation activities were carried out during the GEO-KOMPSAT-2A In-Orbit Test period. The results from the evaluation tool were cross checked with those of the HARRIS, which is the AMI payload vendor. AMI radiometric evaluation activities were conducted through three phases for both sides (Side 1 and Side 2) of AMI payload. Results showed that performances of the key radiometric properties were outstanding with respect to the radiometric requirements of the payload. The effectiveness of the evaluation tool was verified as well.

Upregulation of adiponectin by Ginsenoside Rb1 contributes to amelioration of hepatic steatosis induced by high fat diet

  • Li, Yaru;Zhang, Shuchen;Zhu, Ziwei;Zhou, Ruonan;Xu, Pingyuan;Zhou, Lingyan;Kan, Yue;Li, Jiao;Zhao, Juan;Fang, Penghua;Yu, Xizhong;Shang, Wenbin
    • Journal of Ginseng Research
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    • v.46 no.4
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    • pp.561-571
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    • 2022
  • Background: Ginsenoside Rb1 (GRb1) is capable of regulating lipid and glucose metabolism through its action on adipocytes. However, the beneficial role of GRb1-induced up-regulation of adiponectin in liver steatosis remains unelucidated. Thus, we tested whether GRb1 ameliorates liver steatosis and insulin resistance by promoting the expression of adiponectin. Methods: 3T3-L1 adipocytes and hepatocytes were used to investigate GRb1's action on adiponectin expression and triglyceride (TG) accumulation. Wild type (WT) mice and adiponectin knockout (KO) mice fed high fat diet were treated with GRb1 for 2 weeks. Hepatic fat accumulation and function as well as insulin sensitivity was measured. The activation of AMPK was also detected in the liver and hepatocytes. Results: GRb1 reversed the reduction of adiponectin secretion in adipocytes. The conditioned medium (CM) from adipocytes treated with GRb1 reduced TG accumulation in hepatocytes, which was partly attenuated by the adiponectin antibody. In the KO mice, the GRb1-induced significant decrease of TG content, ALT and AST was blocked by the deletion of adiponectin. The elevations of GRb1-induced insulin sensitivity indicated by OGTT, ITT and HOMA-IR were also weakened in the KO mice. The CM treatment significantly enhanced the phosphorylation of AMPK in hepatocytes, but not GRb1 treatment. Likewise, the phosphorylation of AMPK in liver of the WT mice was increased by GRb1, but not in the KO mice. Conclusions: The up-regulation of adiponectin by GRb1 contributes to the amelioration of liver steatosis and insulin resistance, which further elucidates a new mechanism underlying the beneficial effects of GRb1 on obesity.

Synthesis and Characterization of Collagen Peptide Based Copolymer from Shaving Scrap (셰이빙 스크랩으로부터 콜라겐 펩타이드계 공중합체 합성과 특성)

  • Park, Min Seok;Shin, Soo Beom;Kim, Ho Soo;Kim, Min Soo;Kim, Ha Sun;Jang, Jae Hyeok;Lee, Jin Kye;Lee, Dong Kuk
    • Applied Chemistry for Engineering
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    • v.33 no.6
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    • pp.581-587
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    • 2022
  • The leather industry generates a large amount of hazardous leather waste of various types every year. Among them, shaving scrap is difficult to recycle because it contains chromium ions. Many studies in recent years have shown that shaving scraps can be processed into various types of valuable products, such as adsorbent, filler, and poultry feed. In this study, collagen peptides were extracted from shaving scraps and structurally modified to be developed as new materials with improved physicochemical properties. First, the chromium ions contained in the shaving scraps were removed using a sodium hydroxide solution, and purified through concentration and low-temperature crystallization. The purified collagen peptide was used to prepare the powder using a spray dryer. The extracted collagen peptides were structurally modified by introducing double bonds by reacting with methacrylic anhydride (MAA), and the product was confirmed by 1H NMR spectroscopy. Next, a copolymer was prepared by redox polymerization of the modified collagen peptide (MCP) and 2-ethylhexyl acrylate (2-EHA). The structure of the copolymer was qualitatively confirmed by FT-IR. In conclusion, this study confirmed that collagen peptides can be extracted from shaving scrap and converted into new eco-friendly materials through certain treatments.

Development of Proto-type Program for Automatic Change Detection and Cueing of Multi-temporal KOMPSAT-5 SAR Imagery (다중시기 KOMPSAT-5 SAR 위성영상의 자동변화탐지알림 프로토타입 프로그램 개발)

  • Chae, Sung-Ho;Oh, Kwan-Young;Lee, Sungu
    • Korean Journal of Remote Sensing
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    • v.38 no.6_4
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    • pp.1955-1969
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    • 2022
  • Most of the public and private users who use national satellite information such as the KOMPSAT series mainly use Electro-Optical and Infrared (EO/IR) satellite images, and the utilization of Synthetic Aperture Radar (SAR) images is relatively insufficient. As KOMPSAT-5 currently in operation, KOMPSAT-6 and micro SAR satellite constellation systems are scheduled to be launched in the future, the demand for utilization of SAR satellite information is increasing in various fields. Accordingly, it is necessary to possess core technology for SAR utilization that can support the utilization of SAR satellite information for users. Due to the all-weather properties of SAR system, change detection technology is a key application technology. However, until now, the development of technology that automatic change detection and cueing using SAR images is insufficient. Through this study, the requirements of automatic change detection and cueing function using multi-temporal KOMPSAT-5 SAR satellite images were derived and a prototype program was developed. This prototype program aims to secure independent SAR utilization technology and promote the utilization of domestic SAR satellite information by practitioners in public sector organizations in Korea.