• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.6
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• pp.85-90
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• 2013

In this paper, 6bit SAR ADC tolerant to ionizing radiation is presented. Radiation tolerance is achieved by using the Dummy Gate Assisted (DGA) MOSFET which was proposed to suppress the leakage current induced by ionizing radiation and its comparing sample is designed with the conventional MOSFET. The designed ADC consists of binary capacitor DAC, dynamic latch comparator, and digital logic and was fabricated using a standard 0.35um CMOS process. Irradiation was performed by Co-60 gamma ray. After the irradiation, ADC designed with the conventional MOSFET did not operate properly. On the contrary, ADC designed with the DGA MOSFET showed a little parametric degradation of which DNL was increased from 0.7LSB to 2.0LSB and INL was increased from 1.8LSB to 3.2LSB. In spite of its parametric degradation, analog to digital conversion in the ADC with DGA MOSFET was found to be possible.

• Korean Journal of Food Science and Technology
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• v.22 no.5
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• pp.509-513
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• 1990

Browning and color characteristics of stored mushrooms (Agaricus bisporus)following ionizing irradiation were investigated in connection with quality deterioration. The phenolic compounds of stored mushrooms showed a gradual decreasing tendency, while extractable browning pigments apparently rose from around 3days of storage under the conditions of $9{\pm}1^{\circ}C,\;80{\pm}7%$ RH and packaging with a corrugated paper box wrapped up in PE. ${\gamma}-irradiation$ at 2 to 3 kGy resulted in a significant reduction of their changes. Immediately after treatment, irradiated mushrooms were more discolored, i.e. a lower Hunter L value and higher Hunter a and b values than control. However, the subsequent storage for 15 days resulted in a preventive influence of ionizing energy on mushroom discoloration. This beneficial effect of ionizing energy was somewhat higher in the pilei than in the stipes of mushrooms and was found to increase lineally with increasing doses up to 3 kGy.

• Progress in Medical Physics
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• v.23 no.4
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• pp.285-291
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• 2012

In the present study, we measured the pure beta particle energy spectra of $^{147}Pm$, $^{85}Kr$, $^{90}Sr+^{90}Y$ radionuclide sources. We confirmed the residual maximum energies of KRISS sources meet the requirement of ISO 6980 and calculated mass collision stopping power ratio, which is essential for absolute measurement of absorbed dose from the reference ${\beta}$-rays. The residual maximum energies of KRISS $^{147}Pm$, $^{85}Kr$, $^{90}Sr+^{90}Y$ sources are 0.14, 0.57 and 0.93 MeV, respectively and the mass collision stopping power ratios are 1.123, 1.120 and 1.109, respectively.

• Journal of Radiation Industry
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• v.5 no.1
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• pp.7-13
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• 2011

The present study has been performed to compare the physiological analysis of monocot model plant (rice) in response to ionizing irradiations (cosmic-ray, gamma-ray, and Ion beam). Ionizing radiations were implanted into monocot model plant (rice) seed. After irradiation, the seeds were planted in the plastic pots for a growth period of one month. Thereafter, the morphological and physiological characteristics including malondealdehyde (MDA) and chlorophyll content, activities of antioxidant enzymes in irradiation samples were investigated. We are confirmed that the activity level of MDA and chlorophyll content were not changed by ionizing irradiation samples. However, the free radical contents were increased in all irradiated plants. And the activities of SOD, POD, and APX were significantly increased by irradiation compared with non-irradiation plant.

• Progress in Medical Physics
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• v.33 no.4
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• pp.72-79
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• 2022

Purpose: The proficiency test was conducted to assess the performance of the dosimetry audit service provider in the readout practice of the dose delivered to patients in medical institutions. Methods: A certain amount of the absorbed dose to water for the high-energy X-ray from the medical linear accelerator (LINAC) installed in the Korea Research Institute of Standards and Science (KRISS) was delivered to the postal dose audit package given by the dosimetry audit service provider, in which the radio-photoluminescence (RPL) glass dosimeters were mounted. The dosimetry audit service provider read the RPL glass dosimeters and sent the readout dose value with its uncertainty to KRISS. The performance of the dosimetry audit service provider was evaluated based on the E_n number given in ISO/IEC 17043:2010. Results: The evaluated E_n number was -0.954. Based on the ISO/IEC 17043, the performance of the dosimetry service provider is "satisfactory." Conclusions: As part of the conformity assessment, the KRISS performed the proficiency test over the postal dose audit practice run by the dosimetry audit service provider. The proficiency test is in line with confirming the traceability of the medical institutions to the primary standard of absorbed dose to the water of the KRISS and ensuring the confidence of the dosimetry audit service provider.

• Journal of Institute of Control, Robotics and Systems
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• v.17 no.11
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• pp.1125-1131
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• 2011

This paper presents a control theoretic approach to realizing fault tolerance in asynchronous sequential circuits. The considered asynchronous circuit is assumed to work in space environment and is subject to faults caused by total ionizing dose (TID) effects. In our setting, TID effects cause permanent changes in state transition characteristics of the asynchronous circuit. Under a certain condition of reachability redundancy, it is possible to design a corrective controller so that the closed-loop system can maintain the normal behavior despite occurrences of TID faults. As a case study, the proposed control scheme is applied to an asynchronous arbiter implemented in FPGA.

• Radiation Oncology Journal
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• v.33 no.2
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• pp.66-74
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• 2015

Trace elements play crucial role in the maintenance of genome stability in the cells. Many endogenous defense enzymes are containing trace elements such as superoxide dismutase and metalloproteins. These enzymes are contributing in the detoxification of reactive oxidative species (ROS) induced by ionizing radiation in the cells. Zinc, copper, manganese, and selenium are main trace elements that have protective roles against radiation-induced DNA damages. Trace elements in the free salt forms have protective effect against cell toxicity induced by oxidative stress, metal-complex are more active in the attenuation of ROS particularly through superoxide dismutase mimetic activity. Manganese-complexes in protection of normal cell against radiation without any protective effect on cancer cells are more interesting compounds in this topic. The aim of this paper to review the role of trace elements in protection cells against genotoxicity and side effects induced by ionizing radiation.

• Korean Journal of Environmental Biology
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• v.21 no.4
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• pp.321-327
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• 2003

Differences between the principles for the radiological protection of man and the environment are compared. The derived levels of exposure for man and biota recommended by the international agencies with dose rates for chronic radiation producing effects at different levels of biological organization were given in terms of the biological effects. Cytogenetic effects on plants after an exposure to ionizing radiation at low doses alone and in combination with other factors are discussed. A wide range of experimental data were analysed and the general conclusions were extracted to cover the topics such as non-linearity of dose response, synergistic and antagonistic effects of the combined exposure of different factors, radiation-induced genomic instability, and the phenomena of radioadaptation.

• ALGAE
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• v.31 no.4
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• pp.403-414
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• 2016

The use of ionizing radiation and radioactive elements is becoming increasingly popular with the rapid developments in nuclear technology, radiotherapy, and radio diagnostic methods. However, ionizing radiation can directly or indirectly cause life-threatening complications such as cancer, radiation burns, and impaired immunity. Environmental contamination with radioactive elements and the depletion of ozone layer also contribute to the increased levels of radiation exposure. Radioprotective natural products have particularly received attention for their potential usefulness in counteracting radiation-induced damage because of their reduced toxicity compared with most drugs currently in use. Moreover, radioprotective substances are used as ingredients in cosmetic formulations in order to provide protection against ultraviolet radiation. Over the past few decades, the exploration of marine algae has revealed the presence of radioprotective phytochemicals, such as phlorotannins, polysaccharides, carotenoids and other compounds. With their promising radioprotective effects, marine algae could be a future source for discovering potential radioprotective substances for development as useful in therapeutics.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.1905-1907
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• 2014

Increasingly it is being realized that despite considerable advancements in therapeutic interventions related to treatment of cancer, satisfactory results are still difficult to achieve. Rapidly accumulating evidence has started to shed light on the fact that cancer cells escape from death via constitutive activation of pro-survival signaling cascades. Cell biology and genetics have extensively enhanced our current understanding of the molecular mechanisms that underlie loss of apoptosis in cancer cells. This review is focused on ionizing radiation mediated restoration of TRAIL mediated apoptosis as evidenced by cell culture and animal model studies. Moreover, we also bring to the limelight radiation induced expression of miRNAs and how miRNAs further control response of cancer cells to radiation.