• 한국임상수의학회지
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• 제1권1호
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• pp.33-40
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• 1984

The number of dairy cows diagnosed and treated at Hyup-dong Animal Hospital from July 1983 to June 1984 was amounted to 3,073 heads of Holstein breed and the result of analysis of diseases was as follows : 1. In the topographic diagnostic categories, 41.23% of all cases involved the urogenital system and were observed most prominent. Next were digestive system (22.10%), general and regional (14.55 %), respiratory system (8.20%) and musculoskeletal system (7.06%) in decreasing order. 2. In urogenital system 50.20% of all diagnosis involved metritis and this were most prominent disease. Next were repeat breeder(15.31%), retained placenta (12.79%) and ovary disfunction(9.40 %) in decreasing order. 3. In digestive system 36.82% of all diagnosis involved enteritis and were most prominent. Next were abomasal displacement (29.31%), lumen indigestion (20.32%) and lumen bloat (9.57%) in decreasing order 4. In general and regional diseases, 52.80% of all diagnosis involved ketosis and were most prominent. Next were milk fever (25.50%), downer cow (5.82%) and omphalitis (4.47%) in decreasing order. 5. In respiratory system, 82.54% of all diagnosis involved upper respiratory tract infections and were most prominent. Next were pneumonia (15.87%). 6. In musculoskeletal system, 49.31% of all diagnosis involved foot rot and were most prominent. 7. In milk secreting system, 61.64% of all diagnosis involved mastitis and ere most prominent. Next were stenosis of teat canal (16.35%). 8. Among the individual disease entities, endometritis marked 20.7%, enteritis 8.13%, ketosis 7.68% upper respiratory tract infection 6.77%, repeat bheeder 6.31%, retained placenta 5.27%, abomasal displacement 4.69%, and lumen impaction 4.49%, respectively of total 3,073 cases in decreasing order.

• 한국직업건강간호학회지
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• 제18권1호
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• pp.98-105
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• 2009

Purpose: This study was to analyze the current preventive measures on alcohol-involved accident and the factors that affect such preventive measures in the construction industry. Method: The survey was administered to examine how the preventive measures on alcohol-involved accident were executed using the data of '2005 Occupational Safety and Health Survey' conducted in 2005 by the Occupational Safety and Health Research Institute. For this study, we analyzed 944 work places in the construction industry. Result: The preventive measures on alcohol-involved accident were being executed in 62.1% of construction companies. As for the number of actual preventive measures on alcohol-involved accident, work places in Jeolla-do executed 2.63 times more frequently than those in Chungcheong-do, and work places with the Occupational Safety and Health Conference executed 2.22 times more frequently than those without such a measure. Conclusion: Joining the Occupational Safety and Health Conference was to be one of the most influential ways of preventive measures on alcohol-involved accident in the construction industry. Accordingly, if workers and employers look for active measures and administer them through the Occupational Safety and Health Conference, it will reduce alcohol-involved accident in the construction industry and contribute to the better preventive measures on alcohol-involved accident in the construction and other industries.

• 한방안이비인후피부과학회지
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• 제21권3호
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• pp.36-51
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• 2008

Objective : This study investigated the effects of PR(Pinelliae Rhizoma) on gene expression of lung tissue resected from asthma induced mice using intra-nasal instillation. Methods : Gene expression levels were measured using a microarray technique, and a functional analysis on these genes was conducted. Results : A total of 3270 genes were up-regulated or down-regulated, 860 genes which were lowered by induction of asthma were restored to those of naive animals, Furthermore hand, 1235 genes were lowered to normal levels, which were elevated by induction of asthma. Most of changed genes were involved in signalling pathways. Genes in which expression levels were restored by oral administration of PR were involved in MAPK pathway, focal adhesion, and regulation of actin cytoskeleton etc. Genes of which expression levels were lowered by oral administration of PR were involved in rhodopsin-like receptor activity, zinc ion binding and ATP binding. These genes were also involved in neuroactive ligand receptor interaction, the JAK-STAT signaling pathway and also the T-cell receptor signaling pathway. Conclusion : These results demonstrate the strong possibility that the mechanisms of PR on asthma are involved in neuroactive ligand receptor interaction pathway or related molecules.

• Journal of Periodontal and Implant Science
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• 제46권1호
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• pp.2-9
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• 2016

Purpose: Porphyromonas gingivalis and Tannerella forsythia have been implicated as the major etiologic agents of periodontal disease. These two bacteria are frequently isolated together from the periodontal lesion, and it has been suggested that their interaction may increase each one's virulence potential. The purpose of this study was to identify proteins on the surface of these organisms that are involved in interbacterial binding. Methods: Biotin labeling of surface proteins of P. gingivalis and T. forsythia and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis was performed to identify surface proteins involved in the coaggregating activity between P. gingivalis and T. forsythia. Results: It was found that three major T. forsythia proteins sized 161, 100, and 62 kDa were involved in binding to P. gingivalis, and P. gingivalis proteins sized 35, 32, and 26 kDa were involved in binding to T. forsythia cells. Conclusions: LC-MS/MS analysis identified one T. forsythia surface protein (TonB-linked outer membrane protein) involved in interbacterial binding to P. gingivalis. However, the nature of other T. forsythia and P. gingivalis surface proteins identified by biotin labeling could not be determined. Further analysis of these proteins will help elucidate the molecular mechanisms that mediate coaggregation between P. gingivalis and T. forsythia.

• Genomics & Informatics
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• 제15권2호
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• pp.56-64
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• 2017

We have previously reported that NS-398, a cyclooxygenase-2 (COX-2)-selective inhibitor, inhibited replicative cellular senescence in human dermal fibroblasts and skin aging in hairless mice. In contrast, celecoxib, another COX-2-selective inhibitor, and aspirin, a non-selective COX inhibitor, accelerated the senescence and aging. To figure out causal factors for the senescence-modulating effect of the inhibitors, we here performed cDNA microarray experiment and subsequent Gene Set Enrichment Analysis. The data showed that several senescence-related gene sets were regulated by the inhibitor treatment. NS-398 up-regulated gene sets involved in the tumor necrosis factor ${\beta}$ receptor pathway and the fructose and mannose metabolism, whereas it down-regulated a gene set involved in protein secretion. Celecoxib up-regulated gene sets involved in G2M checkpoint and E2F targets. Aspirin up-regulated the gene set involved in protein secretion, and down-regulated gene sets involved in RNA transcription. These results suggest that COX inhibitors modulate cellular senescence by different mechanisms and will provide useful information to understand senescence-modulating mechanisms of COX inhibitors.

• Journal of Animal Science and Technology
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• 제63권4호
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• pp.673-680
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• 2021

The purpose of this study was to establish a basic principal procedure for the processing of cultured meat. The first stage involved isolating satellite cells from the desired muscle of an animal using enzymatic digestion (i.e., by using proteases, collagenases, and pronases). The second stage involved culturing the isolated muscle satellite cells in a growth medium containing fetal bovine serum and penicillin/streptomycin with growth factors for an optimal period of time. The second stage involved a basic method for the isolated muscle cells to proliferate while sub-culturing to further induce differentiation in gelatin-coated culture dishes with the general culture medium. The third stage involved the induction of differentiation of muscle satellite cells or formation of myotubes using myogenic medium. Lastly, the fourth stage involved the identification of cell differentiation or myotube formation (myogenesis) using fluorescent dyes. Moreover, the principle of these protocols can be applied to perform primary culture of animal cells. This study will assist beginners with the technical aspects of culturing meat (isolation, cultivation, and differentiation of muscle satellite cells as well as identification of myotube formation for myogenesis).

• 대한치과의사협회지
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• 제13권3호
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• pp.231-234
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• 1975

The true cementoma (attached cementoma) is an unusual benign jaw neoplasm fused to the root of the involved tooth. The authors have treated a true cementoma occurs at the right mandibular first molar. The 26 years old male patient who has complained of sweeling and discomfort of the involved tooth. The radiograph showed that the tumor represents a dense radiopacity bordered by a well demarcated peripheral radiolucent zone. Treatment was performed by extraction of the involved tooth with complete enucleation of the tumor. So the operation was done without any complications.

• 한국정밀공학회지
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• 제24권1호
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• pp.93-100
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• 2007

In this study, an investigation was made on bristles for the prosthetic and periodontally involved patients based on the previous studies. The purpose of this study was to investigate the ideal location and dimensions of bristles for the patients who were installed with fixed prostheses and severely involved periodontitis. 3D scanner was used to develop 3D visual models of bristles and teeth. These models were developed to be used for designing the ideal bristles for the prosthetic and periodontally involved patients. For the ideal design of bristle, interproximal area of dental arch and bristle must get into maximum and standard teeth may have to be chosen from many gypsum molds. During the design process the factors should be considered that influence the removal of plaque by bristle.

• Asia Marketing Journal
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• 제18권3호
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• pp.19-34
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• 2016

Product involvement is an important factor in consumer evaluation of co-branding. However, academic discussions over this factor have largely been neglected. This paper bridges this gap and investigates how product involvement moderates the strength of the reciprocal effect on each brand partner. We validate two theory-driven propositions by using a theoretical modeling approach. Proposition 1 explains that the negative reciprocal effect on partnering brands is stronger in the scenario of higher-involved categories than in lower-involved categories. Proposition 2 argues that the positive reciprocal effect on partnering brands can be more significant in the case of lower-involved categories than in higher-involved categories. To the best of our knowledge, we are the first to explore the influence of product involvement on reciprocal effects in the scenario of a moderately-incongruent co-branding alliance.

• 한국디자인학회:학술대회논문집
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• 한국디자인학회 2002년도 가을학술발표대회 디자인학 연구
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• pp.66-67
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• 2002