• 제목/요약/키워드: Investigation and analysis

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Quantitative Analysis of amphetamines in hair by EI-GC-MS using SIM mode with uncertainty estimation

  • Yang, Won-Kyung;Han, Eun-Young;Lee, Jae-Sin;Park, Yong-Hoon;Kim, Eun-Mi;Lim, Mi-Ae;Chung, Hee-Sun
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.169.2-169.2
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    • 2003
  • A method using EI-GC-MS is described for the determination of amphetamines in hair. The method is applied to simultaneous quantify amphetamines (methamphetamine, amphetamine, MDMA and MDA). Drugs were extracted in 1 % HCl in methanol from hair. After derivertization with TFAA, the resulting drugs were separated on HP-5MS column during a 16 min program and identified by mass spectrometry with the SIM mode(EI-GC-MS). (omitted)

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한강(고양시) 고수부지의 환경변화에 따른 곤충 및 저서성대형무척추동물의 분포변화에 관한 분석 (Transformation analysis of environment in downstream Han river (Goyang - shi) by biodiversity and distribution of insect and Benthic Macro-Invertebrates)

  • 송영주;김종갑;배양섭
    • 한국습지학회지
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    • 제7권4호
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    • pp.51-65
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    • 2005
  • The insects and Benthic Macro-Invertebrates are very important for index of investigation. This reserch is executed a field investigation with a date analysis of the laboratory under such as above hypothesis and we have grasped the change of the creature according to the season through the executing of field investigation(We executed six times about the insects, seven times about the Benthic Macro-Inbertebrates each expending from Apr. to Oct. 2004). The result of summary in 2004 show that, we have grasped 12 orders 56 familys 116 species on 2001 and 10 orders 42 familys 78 species on 2002 through the investigation. Also we have grasped 13 orders 53 familys 114 species on 2003 and 12 orders 63 familys 121 speceies on 2004 through the investigation. In the case of enthic Macro-Invertebrates, we executed the analysis through the investigation result expending from 2003 to 2004 due to there is no literature investigation record from 2001 to 2002. We have grasped 8 orders 17 familys 24 species on 2003 and 7 orders 11 familys 24 species on Aug. 2004 through the investigation. We executed the analysis about an each condition due to it is difficult to compare the above result simply by the various variable at the investigation. We expect that it become the fundamental reference data to establish a efficient mode of life undo plan after grasped the inhabitation and movement route of creature inside the river through this reserch.

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모발에서 마약류 분석의 법과학적 고찰 - 마약류 범죄수사에서 모발 감정결과의 증거사용에 대해서 - (Forensic Study about Hair Analysis as Legal Evidence of Drug Abuse Crime)

  • 박용훈;한은영;이수연
    • 약학회지
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    • 제52권6호
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    • pp.452-465
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    • 2008
  • Hair analysis for drugs of abuse offers the crucial potential advantage when compared to urine, such as the longer time window of drug intake, which makes retrospective investigation of chronic and/or past consumption. This paper reviews the physiological basis of hair growth, mechanism of drug incorporation, analytical methods, result interpretation and practical application of hair analysis. Moreover, to facilitate the court's decision regarding specific circumstances surrounding the crime, this review demonstrated that the results of hair analysis not only should be admitted as scientific evidence of drug use but also could legally improve reliability of the evidence.

GC/MS를 이용한 혈액 중 유기인제류 농약의 동시 분석에 관한 방법의 유효화 (Method Validation for the Simultaneous Analysis of Organophosphorous Pesticides in Blood by GC/MS)

  • 박미정;양자열;김기욱;박유신;정희선;이상기
    • Environmental Analysis Health and Toxicology
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    • 제20권4호통권51호
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    • pp.297-302
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    • 2005
  • The purpose of this study was to provide the standard method for the analysis of organophosphorous pesticides such as chlorpyrifos, diazinon, malathion and parathion in blood. We performed method validation for these pesticides in blood according to EURACHEM (A focus For Analytical Chemistry in Europe) guide. For the analysis of the pesticides, we used solid-phase extraction ,column (Waters Oasis $HLB^{(R)}$. After the extraction, the supernatants were evaporated to dryness under the nitrogen stream. They were analyzed by gas chromatography/mass spectrometry (GC/MS) after reconstituting with ethanol. Terbufos was used as an internal standard. To validate this method, we performed verification procedures with the following parameters: selectivity, linearity of calibration, accuracy, precision, limit of detection and quantification. Validation data according to Eurachem guide were adequate for our purpose for the analysis of chlorpyrifos, diazinon, malathion and parathion in blood.

시스템 보안 강화를 위한 로그 분석 도구 ILVA와 실제 적용 사례 (ILVA: Integrated audit-log analysis tool and its application.)

  • 차성덕
    • 정보보호학회논문지
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    • 제9권3호
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    • pp.13-26
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    • 1999
  • 인터넷의 급속한 발전과 함께 정보 시스템의 보안 위협인 침입 사고도 급증하고 있다. 보다 강 화된 보안 메커니즘이 요구되고 있다. 시스템 로그 분석은 이런 침입 사실을 탐지하고 침입 자를 추적하 기 위해 필수적인 과정이나 로그 자료의 종류와 형태의 다양함으로 인해 자동화된 로그 수 집 및 분석이 현실적으로 어려운 상태이다. 우리는 침입 추적에 필요한 로그 자료의 형태를 정의하고 방 대한 로그 자 료로부터 효율적으로 로그수집, 분석할수 있는 도구를 설계 및 구현하였다. 이 논문에서는 개발된 도구 를 사용하여 실제 침입 추적을 한 경험을 소개하고 도구의 향후 개선 방향을 제시한다 Widespread use of Internet despite numerous positive aspects resulted in increased number of system intrusions and the need for enhanced security mechanisms is urgent. Systematic collection and analysis of log data are essential in intrusion investigation. Unfortunately existing logs are stored in diverse and incompatible format thus making an automated intrusion investigation practically impossible. We examined the types of log data essential in intrusion investigation and implemented a tool to enable systematic collection and efficient analysis of voluminous log data. Our tool based on RBDMS and SQL provides graphical and user-friendly interface. We describe our experience of using the tool in actual intrusion investigation and explain how our tool can be further enhanced.

주성분분석을 이용한 환경영향평가와 사후환경조사의 비교 및 평가에 관한 사례연구 (A Case Study on the Comparison and Assessment between Environmental Impact Assessment and Post-Environmental Investigation Using Principal Component Analysis)

  • 조일형;김용섭;조경덕
    • 한국환경보건학회지
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    • 제31권2호
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    • pp.134-146
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    • 2005
  • Environmental monitoring system has been adopted and supplemented as inspection measures for the quantitative and qualitative changes of environmental impact assessment (EIA). This study compares the results of environmental impact assessment with the results of post-environmental investigation using a correction and principal component analysis (PCA) in the housing development project. Correlation analysis showed that most of air quality variables including TSP, $PM_{10},\;NO_2$, CO were linearly correlated with each other in the environmental impact assessment and the post-environmental investigation. In the water quality, pH and BOD were well correlated with the DO and SS, respectively. As a result of correlation analysis in the noise and vibration, noise in day and night and vibration in day and night were related to each other between EIA and the post-environmental investigation. From the results of analysis of soil, Cu with Cd, Cu with Pb, and Cd with Pb were related to each other in EIA. Principal component analysis (PCA) showed a powerful pattern recognition that had attempted to explain the variance of a large dataset of inter-correlated variable with a smaller set of independent variables (principal components). Principal component (PC1) and principal component (PC2) were obtained with eigenvalues> 1 summing almost $90\%$ of the total variance in the all of the items(air, water, noise, vibration and soil) in EIA and post-environmental investigation.