• The Journal of the Korea Contents Association
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• v.20 no.7
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• pp.56-65
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• 2020

The purpose of this research is to study the excellence and originality of the Joseon artillery(Jungwan-gu) through an effective restoration. Jungwan-gu that was used during the Japanese Invasion of Korea in 1592 was able to maintain its maritime dominance based on cutting-edge technology of its time. Joeson artillery(Jungwan-gu) was used in major naval/land battles during the Japanese Invasion of Korea in 1592 and is an important cultural heritage that provides a glimpse into Joeson people's will to defend the nation from foreign invasion. For further historical verification such as operational method of Jungwan-gu, extensive research in various fields including size, proportions, structure, materials, and casting method were required. Accordingly, for a more effective research on Jungwan-gu, cutting-edge technologies such as 3D scanning and 3D printing were utilized. Firstly, 3D scanning, modeling, and printing technology were applied to identify the morphological characteristics of Jungwan-gu. Through this, we were able to reach our research objective of identifying the size, internal structure, and proportionality of Jungwan-gu. In addition, by studying the form, operation, casting methods, and other characteristics, the restoration of Jungwan-gu provided us with an important opportunity to verify the dominance and originality of the Joeson era's science and technology during the Japanese Invasion of 1592. This reaserch subject participated in the "4th 3D printing BIZCON Contest" and won the Minister Prize of Science and Technology Information and Communication.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.18 no.6
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• pp.227-237
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• 2015

From January 2013 to October 2015, weed invasion control techniques was tested in the test road of Jungbunaeryuk expressway so as to collect preliminary data for the management methods of the upper exterior banking of expressway shoulders. Then, monitoring was conducted and its results are as follows. Mat (sheet), solidifying agent, and mulching (wood chips) were applied for the test and their initial effects of preventing weed invasion were all excellent. It was found that the homogeneity of the wood chip mulching method needs to improve. In the mat method and the mulching method were found to have the most excellent economic feasibility and aesthetics, respectively. The covering degree was found to be the highest at 80% in the control site, followed by the wood chip site at 20% and the solidifying agent site and the non-woven fabric site at 5% each. As for species diversity, the control had the largest variety of species. Two years after the construction, many different species of plants invaded and were growing. Plants including weed didn't tend to invade the slopes applied with non-woven fabric. In addition, weed didn't invade the solidifying agent site and the aesthetics of the upper exterior banking of expressway shoulders was found to be excellent. The wood chip site was found to require consistent management for preventing weed invasion. The mat (sheet) site, the solidifying agent site, and the wood chip mulching site were found to have excellent weed prevention effects. As time passed, the mat (sheet) site and the solidifying agent site showed better weed prevention effects. However, they need consistent monitoring for further application.

• BMB Reports
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• v.52 no.8
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• pp.490-495
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• 2019

Using tunneling nanotubes (TNTs), various pathological molecules and viruses disseminate to adjacent cells intercellularly. Here, we show that the intracellular invasion of Mycoplasma hyorhinis induces the formation of actin- and tubulin-based TNTs in various mammalian cell lines. M. hyorhinis was found in TNTs generated by M. hyorhinis infection in NIH3T3 cells. Because mycoplasma-free recipient cells received mycoplasmas from M. hyorhinis-infected donor cells in a mixed co-culture system and not a spatially separated co-culture system, direct cell-to-cell contact via TNTs was necessary for the intracellular dissemination of M. hyorhinis. The activity of Rac1, which is a small GTP binding protein, was increased by the intracellular invasion of M. hyorhinis, and its pharmacological and genetic inhibition prevented M. hyorhinis infection-induced TNT generation in NIH3T3 cells. The pharmacological and genetic inhibition of Rac1 also reduced the cell-to-cell dissemination of M. hyorhinis. Based on these data, we conclude that intracellular invasion of M. hyorhinis induces the formation of TNTs, which are used for the cell-to-cell dissemination of M. hyorhinis.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.26 no.2
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• pp.523-531
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• 2016

This paper studies the empirical relationship between various privacy protection measures and personal information invasion experience of firms and individuals using rich and heterogeneous survey data. By analyzing PSM models. we get the following results: first, the treatment group which have more technical measures and/or IS investment tends to experience more privacy invasion than the control group which have less of them. second, the reverse causality, that is firms and individuals with more experience of privacy invasion tends to take more measure for personal information protection, is found to exist. From these result, we discuss proper privacy policies implications in respects of attackers benefits and individual irrationality.

• Journal of forensic and investigative science
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• v.2 no.2
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• pp.5-20
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• 2007

During the period from 2001 to 2005, 29,892 burglaries took place in Korea with the approximate average annual number - 5,978 cases. This study was conducted to analyze the reported burglaries and the result was summarized as follows. There were 8,605 residential invasion burglaries (28.8%) as the most frequent characteristic pattern. The exit was used as the most frequent invasion route for 4,031 invasion burglaries (64.3%), and an unlocked exit door or window was used as the most frequent invasion method for 2,462 invasion burglaries (28.6%). The hours just after midnight (between 00:00 and 04:00) were the most frequent time for invasion burglary to occur. Also, 5,652 burglaries occurred on Wednesday which was twice higher than on Sunday (2,988 burglaries). It was shown that the number of persons injured during burglaries were 260 deaths and 10,610 injuries. The places of the highest occurrence were the street with 10,183 burglaries (34%) and then residential place with 7,527 burglaries (approximately 25%). One-man burglary was the highest complicity: 15,012 offenders (56.1%). The knife was used as the most frequent instrument for 6,498 burglaries (24,3%) what is rare, while no criminal tool or instrument was used for 15,631 burglaries (58.4). During the period from 2001 to 2006, 1,506 burglaries occurred in Daegu and the average annual number was 251 burglaries. Among those,515 residential invasion burglaries (34.2%) took place and the average annual number was approximately 86 cases. The hours just after midnight (between 00:00 and 04:00) were the most frequent time for invasion burglary to occur (194 cases, 37.7%), the place of the highest invasion occurrence was the residential place (259 cases, 50.3%), and the exit was used as the most frequent invasion route (87 cases, 37.7%). An unlocked exit door or window was the most frequent invasion method (65 cases, 25.1%). In addition, pretending to be a delivery man, visitor or following the victim methods were used for 26 burglaries (10%). It is apparent that personal preventive measures against crimes, as well as governmental and social measures, play an important role in preventing burglaries. In particular, based on the analyzed result that an unlocked window or exit door was most frequently used for reported burglaries, it seems that there is a lack of understanding of crime prevention while little effort has been made to prevent crimes. Although everyone knows that locking a door is one of the basic measures to prevent crimes, many people tend to pay little attention to lock a door properly so burglary takes place. This study, therefore, is intended to encourage people to pay more careful attention to crime prevention, in order to help reduce the probability of burglary. With the recent improvement in social understanding of scientific crime investigation, a wide variety of police professions, including crime analysts, crime victim police counselors and coroners, have been prepared to develop the scientific crime investigation and crime analysis. In addition, it is hoped that further this study will contribute to encourage studies on crime prevention to be carried out in the future.

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.177-177
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• 2003

Tumor cell invasion and metastasis are a complex multistep process that involves the degradation of extracellular matrix proteins by matrix metalloproteinases (MMPs). Tissue inhibitor of metalloproteinase-1 (TIMP-1) acts as a negative regulator of matrix metalloproteinase and thus prevents tumor cell invasion and metastasis by preserving extracellular matrix integrity.(omitted)

• Journal of Gastric Cancer
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• v.7 no.2
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• pp.74-81
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• 2007

Purpose: Routine pancreatico-splenectomy with total gastrectomy should no longer be considered as the standard surgical procedure for gastric cancer because of the lack of proven surgical benefit for survival. The aim of this study is to evaluate the clinicopathologic factors and the survival of patients with locally advanced gastric cancer and they had undergone combined pancreatico-splenectomy with a curative intent. Material and Methods: We retrospectively reviewed a total of 118 patients who had undergone total gastrectomy with distal pancreatico-splenectomy from 1990 to 2001. The patients were divided into 2 groups: 90 patients who were free from cancer invasion (group I), and 28 patients with histologically proven cancer invasion into the pancreas (group II). The various clinicopathologic factors that were presumed to influence survival and the survival rates were analyzed. Results: The rate of pathological pancreatic invasion was 23.7%. The tumor stage, depth of invasion, pancreas invasion, lymph node metastasis, lymph node ratio, curability and the hepatic and peritoneal metastasis were statistically significance on univariate analysis. Among these factors, the tumor stage, lymph node ratio and curability were found to be independent prognostic factor on multivariate analysis. The 5-years survival rates were 36.2% for group I and 13.9% for group II. The morbidity rate was 22.1%, and this included pancreatic fistula (5.1%), intra-abdominal abscess (4.2%) and bleeding (4.2%). The overall mortality rate was 0.8%. Conclusion: Combined distal pancreatico-splenectomy with total gastrectomy with a curative intent was selectively indicated for those patients with visible tumor invasion to the pancreas, a difficult complete lymph node dissection around the distal pancreas and spleen, and no evidence of liver metastasis or peritoneal dissemination.

• Journal of Korean Neurosurgical Society
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• v.30 no.3
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• pp.263-271
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• 2001

Objective : Glioblastomas, the most common type of primary brain tumors, are highly invasive and cause massive tissue destruction at both the tumor invading edges and in areas that are not in direct contact with glioma cells. As a result, patients with high-grade gliomas are faced with a poor prognosis. Such grim statistics emphasize the need to better understand the mechanisms that underlie glioma invasion, as these may lead to the identification of novel targets in the therapy of high grade gliomas. Protein kinase C(PKC) is a family of serine/threonine kinases and an important signal transduction enzyme that conveys signals generated by ligand-receptor interaction at the cell surface to the nucleus. PKC appears to be critical in regulating many aspects of glioma biology. The purpose of this study was to assess accurately the role of PKC in the invasion regulation of human gliomas based on hypothesis that protein kinase C(PKC) is functional in the process of glial tumor cell invasion. Method : To test this hypothesis, U-87 malignant glioma cell line intracellular PKC levels were up and down regulated and their invasiveness was tested. Intracellular PKC level was characterized using PKC activity assays. Invasion assays including barrier migration and spheroid confrontation were used to study the relationship between PKC concentration and invasiveness. Result : The cell line which were treated by PKC inhibitor tamoxifen and hypericin exhibited decreased PKC activity and decreased invasive abilities dose dependently both in matrigel invasion assay and tumor spheroid fetal rat brain aggregates(FRBA) confrontation assay. However, the cell line that was treated by PKC activator 12-O-tetradecanylphorbol-13acetate(TPA) did not exhibit increases in either PKC activity or invasive ability. Conclusion : These studies suggest that PKC may be a useful molecular target for the chemotherapy of glioblastoma and other malignancies and that a therapeutic approach based on the ability of PKC inhibitors may be helpful in preventing invasion.

• Proceedings of the PSK Conference
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• 2002.04a
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• pp.59-59
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• 2002

• 대한치과보철학회:학술대회논문집
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• 1999.04a
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• pp.93.2-94
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• 1999