• The Journal of Korean Medicine
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• v.25 no.2
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• pp.173-183
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• 2004

Objectives : Oxidative stress can induce negative responses such as growth inhibition or cell death by necrosis or apoptosis due to the intensity of the oxidative stress, as well as positive responses such as cellular proliferation or activation. We examined the effect of Jihwangeumja on this process. Methods and Results : We analyzed the influence of oxidative stress and agents that modify its effect in human umbilical vein endothelial cell (HUVEC). Oxidative stress was induced by $B_2O_2$. With induced oxidative stress the results obtained indicate that it has a harmful effect over cell function and viability, and that this effect is dose and time dependent. When oxidative stress increased, Jihwangeumja reduced cell damage and had protective functions. $B_2O_2$, induced the apoptosis of HUVEC through the activation of intrinsic caspases pathway as well as mitochondrial dysfunction. A significant increase in cell survival was observed in culture cells with oxidative stress when they were treated with Jihwangeumja. Conclusions : These results suggest that Jihwangeumja may be potentially useful to treat HUVEC against oxidative damages mediated by modulation of caspase protease and mitochondrial dysfunction.

• Transactions of Materials Processing
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• v.15 no.8 s.89
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• pp.544-549
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• 2006

In this work, we have employed the strain gradient plasticity theory to investigate the effect of material size on the deformation behavior in metal forming process. Flow stress is expressed in terms of strain, strain gradient (spatial derivative of strain) and intrinsic material length. The least square method coupled with strain gradient plasticity was used to calculate the components of strain gradient at each element of material. For demonstrating the size effect, the proposed approach has been applied to plane compression process and micro rolling process. Results show when the characteristic length of the material comes to the intrinsic material length, the effect of strain gradient is noteworthy. For the microcompression, the additional work hardening at higher strain gradient regions results in uniform distribution of strain. In the case of micro-rolling, the strain gradient is remarkable at the exit section where the actual reduction of the rolling finishes and subsequently strong work hardening take places at the section. This results in a considerable increase in rolling force. Rolling force with the strain gradient plasticity considered in analysis increases by 20% compared to that with conventional plasticity theory.

• Journal of Preventive Medicine and Public Health
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• v.13 no.1
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• pp.19-25
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• 1980

The Occupational Job Stress Indicies Questionnaire is a selfadministered instrument consisting of 48 questions which are designed to collect the perceived Job stress about individual. This questionnaire was translated into Korean and applied to the selected groups of 300 blue collar workers musical manufacture industy for the purpose of assessing the it's reliability from April 1. to July 30, 1980. The results obtained were as follows; 1. The range of reliability coefficients for all indices was. 45-.75 which was lower than .54-.87 of original. 2. The inter-item correlation matrix for all items comprising an index along with the intercorrelation of these items with the items comprising closely related indices. 3. The reliability of JOB SATISFACTION, INTRINSIC REWARDS and IMPORTANCE REWARDS revealed .14-.20 lower than that of original. On the point of view, some items should be adjusted in parallel with acutual situation of Korea through making a cultural comparative study and item factor analysis.

• Proceedings of the Korean Geotechical Society Conference
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• 2000.11a
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• pp.361-368
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• 2000

In other to examine the compressibility characteristics of cohesive soils in the mouth of the Nakdong river, the oedometer tests were peformed on undisturbed and reconstituted samples obtained by continuous boring typically at 3 different sites. It is meaningful to compare the consolidation behavior of natural clays with a reference state because the natural clays are depending on the stress history, sedimentary environment and geological history. In this study, the insitu state of the Pusan clays was investigated using the concepts of ISL(Nagaraj, 2000) and ICL and SCL(Burland, 1990). And for the purpose of confirming the existence of the underconsolidated clays, a standpipe type piezometer test and a dissipation test by piezocone were performed at their sites. Consequently, the Pusan clays were evaluated as normally consolidated clays.

• Archives of Plastic Surgery
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• v.32 no.5
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• pp.656-659
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• 2005

Plantar corn is a circumscribed and sharply demarcated hard mass of traumatic hyperkeratosis, which has a central core impacting the dermis deeply and causes pain while walking. The cause of the corn is the mechanical stress to the skin induced by several causative factors; extrinsic(tight shoes) or intrinsic(bony prominence), or combined(the claw toe). We found 7 cases of patients with a painful recurrent plantar corn which had an epidermal cyst under its lesion. These corns and cysts were excised totally and there was no recurrence in all cases during two to four months follow-up period. We think that an epidermal cyst may be another intrinsic factor for the development of a plantar corn. So, an epidermal cyst should be considered once in a recurrent plantar corn to be recalcitrant against popular treatments.

• Journal of Nutrition and Health
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• v.53 no.1
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• pp.54-67
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• 2020

Purpose: This study examined the relationship between job stress, attributes of health functional food (HFF) selection, and consumption values for information technology (IT) workers, and analyzed the factors influencing the selection of HFF to improve health by making the right choice of HFFs. Methods: Three hundred forty IT workers in Gyeonggi area participated in the study. The participants were divided into low or high job stress group. The differences in participants' general characteristics, attributes of HFF selection, and HFF consumption values were investigated, and the mediating effects of HFF consumption values on the relationship between job stress levels and the HFF selection attributes were analyzed. Results: Job stress levels were high in those IT workers with a length of service < 5 years (p = 0.013). The group with lower job stress levels had a higher tendency to consider the ingredients contained in HFF products (p < 0.001), and their efficacy (p = 0.047). They also showed greater emotional value for a sense of security from consuming HFFs to stay healthy (p = 0.047). The group with higher job stress levels had greater epistemic value in that their choice of HFFs differentiated them from the other workers (p = 0.036). Higher job stress was associated with less consideration of the intrinsic attributes such as ingredients and efficacy of the HFF selection attributes (p = -0.113), emotional value of the HFF consumption values (p = -0.136), and the functional value such as practicality, price, and safety (p = -0.134). The job stress level influenced the intrinsic attributes through the functional and emotional values, demonstrating that the functional and emotional values had appropriate mediating effects on the relationship between job stress levels and intrinsic attributes. Conclusion: Education needs to be provided for workers to relieve job stress and improve the functional and emotional values, which contributes to choosing the appropriate HFFs.

• Journal of Korean Clinical Nursing Research
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• v.29 no.1
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• pp.1-11
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• 2023

Purpose: The purpose of this study was to identify the influencing effects of job stress, professional autonomy, and reciprocity on the job embeddedness among comprehensive nursing care unit nurses. Methods: The participants in this study were 147 nurses who have worked for over 6 months in Comprehensive Nursing Care Unit. Data were collected from January 3 to January 31, 2022 from six general hospitals with more than 300 beds in three cities in G, G and P. Results: As the results of hierarchical regression analysis, job embeddedness was lower when nurses had clinical experiences for 1 to under 5 years (β=-.49, p<.001), 5 to under 10 years (β=-.27, p=.035), 10 to under 20 years (β=-.54, p<.001) compared to those who had clinical experiences for more than 20 years. Also, job embeddedness was higher when there was greater balance within team caregiving of reciprocality (β=.27, p<.001) and intrinsic reward (β=.22, p=.003), and lower role conflict (β =-.27, p<.001). Conclusion: The results of the study showed that job embededness would increase if the role conflict of comprehensive nursing care unit nurses reduces, if there was a culture that the members can make cooperative relationship with other health care professionals and, if there was an appropriate intrinsic reward depending on their work experience.

• Corrosion Science and Technology
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• v.5 no.2
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• pp.69-76
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• 2006

Premature cracking of the epoxy coatings applied on ship's ballast tanks(BT) can lead to damage of ship's hulls. To avoid this, it's important to have clear understanding of the underlying mechanism and primary factors of the coating crack. In this study, the efforts were made to clarify the integrated effects of main factors, i.e., initial coating shrinkage, thermally induced strain, steel-structural strain and the intrinsic coating flexibility at the initial and after aging, to the early cracking phenomena of epoxy coating in the ship's ballast tank. The coating crack is caused by combination of thermal stress, structural stress, and internal stresses which is closely related to chemical structures of the coatings. On the other hand, thermal stresses and dimensional stabilities would rarely play a major role in coating crack for ballast tank coatings with rather large flexibility. Crack resistance of the coatings at early stages can be estimated roughly by measuring internal stress, FT-IR and $T_g$ value of the coatings. A new screening test method was also proposed in this study, which can be possibly related to the long-term resistance of epoxy-based paints to cracking.

• Molecules and Cells
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• v.25 no.3
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• pp.438-445
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• 2008

Leaf senescence is a highly regulated genetic process that constitutes the last stage of plant development and provides adaptive fitness by relocating metabolites from senescing leaves to reproducing seeds. Characterization of various senescence mutants, mostly in Arabidopsis, and genome-wide analyses of gene expression, have identified a wide array of regulatory components, including transcription factors and enzymes as well as signaling molecules mediating growth hormones and environmental stress responses. In this work we demonstrate that a membrane-associated NAC transcription factor, NTL9, mediates osmotic stress signaling in leaf senescence. The NTL9 gene is induced by osmotic stress. Furthermore, activation of the dormant, membrane-associated NTL9 is elevated under the same conditions. A series of senescence-associated genes (SAGs) were upregulated in transgenic plants overexpressing an activated form of NTL9, and some of them were slightly but reproducibly downregulated in a T-DNA insertional NTL9 knockout mutant. These observations indicate that NTL9 mediates osmotic stress responses that affect leaf senescence, providing a genetic link between intrinsic genetic programs and external signals in the control of leaf senescence.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1997.10a
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• pp.16-23
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• 1997

The Reproducing Kernel Particle Method (RKPM), one of the popular meshless methods, is developed and applied to stress concentration problems. Since the meshless methods require only a set of particles (or nodes) and the description of boundaries in their formulation, the adaptivity can be implemented with much more ease than finite element method. In addition, due to its intrinsic property of multiresolution, the shape function of RKPM provides us a new criterion for adaptivity. Recently, this multiple scale Reproducing Kernel Particle Method and its adaptive procedure have been formulated for large deformation problems by the authors. They are also under development for damage materials and localization problems. In this paper the multiple scale RKPM for linear elasticity is presented and the adaptive procedure is applied to stress concentration problems. Therefore, this work may be regarded as the edition of linear elasticity in the complete framework of multiple scale RKPM and the associated adaptivity.