• Title/Summary/Keyword: Intraclass Correlation

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Usefulness of intraoperative transcranial sonography in patients with traumatic brain injuries: a comparison with postoperative computed tomography

  • Mahn Jeong Ha;Seung Han Yu;Jung Hwan Lee;Hyuk Jin Choi;Byung Chul Kim
    • Journal of Trauma and Injury
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    • v.36 no.1
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    • pp.8-14
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    • 2023
  • Purpose: The aim of this study was to assess the agreement between intraoperative transcranial sonography (TCS) and postoperative computed tomography (CT) in patients with traumatic brain injuries. Methods: We performed a retrospective cross-sectional study of 35 patients who underwent TCS during surgery, among those who presented to a regional trauma center and underwent decompressive craniectomy between January 1, 2017 and April 30, 2020. Results: The mean difference between TCS and CT in measuring the midline shift was -1.33 mm (95% confidence interval, -2.00 to -0.65; intraclass correlation coefficient [ICC], 0.96; P<0.001). An excellent correlation was found between TCS and CT in assessing contralateral subdural hematomas (ICC, 0.96; P<0.001) and focal hematoma lesions (ICC, 0.99; P<0.001). A very good correlation between TCS and CT was found for measurements of ventricle width (ICC, 0.92; P<0.001). Conclusions: TCS during surgery is considered an effective diagnostic tool for the detection of intraoperative parenchymal changes in patients with traumatic brain injuries.

Comparison of Batch Assay and Random Assay Using Automatic Dispenser in Radioimmunoassay (핵의학 체외 검사에서 자동분주기를 이용한 Random Assay 가능성평가)

  • Moon, Seung-Hwan;Lee, Ho-Young;Shin, Sun-Young;Min, Gyeong-Sun;Lee, Hyun-Joo;Jang, Su-Jin;Kang, Ji-Yeon;Lee, Dong-Soo;Chung, June-Key;Lee, Myung-Chul
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.4
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    • pp.323-329
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    • 2009
  • Purpose: Radioimmunoassay (RIA) was usually performed by the batch assay. To improve the efficiency of RIA without increase of the cost and time, random assay could be a choice. We investigated the possibility of the random assay using automatic dispenser by assessing the agreement between batch assay and random assay. Materials and Methods: The experiments were performed with four items; Triiodothyronine (T3), free thyroxine (fT4), Prostate specific antigen (PSA), Carcinoembryonic antigen (CEA). In each item, the sera of twenty patients, the standard, and the control samples were used. The measurements were done 4 times with 3 hour time intervals by random assay and batch assay. The coefficient of variation (CV) of the standard samples and patients' data in T3, fT4, PSA, and CEA were assessed. ICC (Intraclass correlation coefficient) and coefficient of correlation were measured to assessing the agreement between two methods. Results: The CVs (%) of T3, fT4, PSA, and CEA measured by batch assay were 3.2$\pm$1.7%, 3.9$\pm$2.1%, 7.1$\pm$6.2%, 11.2$\pm$7.2%. The CVs by random assay were 2.1$\pm$1.7%, 4.8$\pm$3.1%, 3.6$\pm$4.8%, and 7.4$\pm$6.2%. The ICC between the batch assay and random assay were 0.9968 (T3), 0.9973 (fT4), 0.9996 (PSA), and 0.9901 (CEA). The coefficient of correlation between the batch assay and random assay were 0.9924(T3), 0.9974 (fT4), 0.9994 (PSA), and 0.9989 (CEA) (p<0.05). Conclusion: The results of random assay showed strong agreement with the batch assay in a day. These results suggest that random assay using automatic dispenser could be used in radioimmunoassay.

Comparative analysis of blood glucose test results on the forearm, finger, and vein (팔, 손가락, 정맥에서 채취한 혈액의 혈당검사결과 비교 분석)

  • Kim, Kyung-Ah;Lee, In-Kwang;Shin, Eun-Young;Kim, Yang-Mi;Kim, Kyoung-Oak;Cha, Eun-Jong;Park, Kyung-Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.4
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    • pp.1751-1758
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    • 2012
  • Capillary blood sampling on the forearm reduces pain caused by skin puncture. The present study compared the blood glucose test results performed at different sampling sites of the forearm, finger, and vein to evaluate clinical validity of this alternative site blood sampling technique. Subjects numbered 555 including 61 diabetic patients participated to measure the glucose concentration on the finger ($G_F$) and the forearm ($G_A$) with a portable glucometer under overnight fasting state. Then, the venous glucose concentration ($G_V$) was measured in 514 subjects in less than 1 hour. The test results were analyzed by simple linear regression, intraclass correlation, and Passing-Bablok regression techniques. $G_A$ was highly correlated with $G_F$ or $G_V$ showing the correlation coefficients (r) of approximately 0.97 (P<0.0001) in the normal group. The patient group also resulted similarly high correlation with only slightly lower r value. The mean differences in glucose concentration were less than ${\pm}10mg/dL$ regardless of the sampling sites. Intraclass correlation coefficients were slightly smaller than r but very much similar in value in both groups. The 95% confidence intervals of the slope as well as the intercept in the Passing-Bablok regression analysis were < ${\pm}20%$ and < ${\pm}20mg/dL$, respectively, which were within the clinically acceptable ranges. These three statistical techniques introduced in the present study well demonstrated the consistency of $G_A$ with $G_F$ and $G_V$. Therefore, the forearm blood glucose test could be considered as clinically valid under fasting condition.

The Reliability and Validity of Figure-of-8 Walk Test in Patients with Stroke (뇌졸중 환자에서 Figure-of-8 walk test의 신뢰도와 타당도)

  • Kim, Yang-Ho;Lim, Jae-Heon
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.10 no.1
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    • pp.29-37
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    • 2012
  • Purpose : The purpose of this study was to establish intra-rater, inter-rater, test-retest reliability, and concurrent validity of figure-of-8 walk test in people with stroke. Methods : The subjects of this study were 17 patients who were diagnosed with a stroke. Subjects were tested twice by the same raters, with 1 day between tests. Subjects were assessed by two physical therapists. Test-retest reliability was calculated using intraclass correlation coefficients (ICC). The concurrent validity was demonstrated by spearman correlation of F8WT with 10m walking test (10MWT), timed up and go test (TUG), Berg balance scale (BBS), dynamic gait index (DGI) and four square step test (FSST). Results : Intra-rater, inter-rater, test- retest of F8WT time, showed high reliability. Intra-rater, inter-rater, test-retest of F8WT steps demonstrated high reliability. Intra-rater, inter-rater, test-retest of F8WT total smoothness score showed below moderate reliability. There was a significant positive correlation of F8WT time with 10MWT, TUG, FSST. There was a significant negative correlation of F8WT time with DGI, BBS. There was a significant positive correlation of F8WT steps with 10MWT, TUG, FSST. There was a significant negative correlation of F8WT steps with DGI. There was a significant positive correlation of F8WT test total smoothness score with BBS. Conclusion : The time, and number of steps in F8WT show high inter, intra-rater, test-retest reliability. The F8WT smoothness shows below moderate reliability. The F8WT shows high concurrent validity with other comparable balance, and walking tests. The F8WT is a valid and reliable measure for assessing walking function in patients with a stroke.

Identifying Key Factors to Affect Bus Headway Deviation using Hierarchical Linear Model (Seoul Case Study) (HLM을 이용한 버스차두간격 편차에 미치는 요인분석 (서울시사례를 중심으로))

  • Lee, Ho-Sang;Kim, Do-Gyeong;Kim, Yeong-Chan;Hwang, Gyeong-Su
    • Journal of Korean Society of Transportation
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    • v.27 no.6
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    • pp.119-127
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    • 2009
  • It has been known that bus route and company related characteristics have influences on punctuality, but fewer research have been conducted. Independent variables used in this study were selected using correlation analysis, and OLS(Ordinary Least Square) and HLM(Hierarchical Linear Model) were employed to identify factors affecting bus punctuality(headway deviation). The results showed that ICC(intraclass Correlation Coefficient) is 0.10, indicating that hierarchical linear models are more adequate for these data because there is effective variation in the subjects between companies. Punctuality was found to be negatively associated with the number of vehicles, the number of persons per vehicle, and total travel time. On the other hand, average headway and company size have a positive relationship with punctuality. Therefore, the number of vehicles per route, average headway, and the number of vehicles managed by a company should be considered for more accurately evaluating the management of piunctuality.

A Clinical Study on the Pattern-Specific Cut-Point for the Pattern Identification Diagnostic Tool for Climacteric and Postmenopausal Syndrome (갱년기장애 및 폐경기증후군 변증진단 도구의 진단결과 도출을 위한 변증별 절단점 연구)

  • Lee, In-Seon;Kim, Jong-Won;Jeon, Soo-Hyung;Chi, Gyoo-Yong;Kang, Chang-Wan
    • The Journal of Korean Obstetrics and Gynecology
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    • v.32 no.2
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    • pp.29-49
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    • 2019
  • Objectives: This study was a methodological study to verify the reliability and validity and to make a diagnosis of a diagnostic tool for climacteric and postmenopausal syndrome pattern identification (CaPSPI). Methods: This study was conducted from June 1, 2018 to October 18, 2018 with ${{\bigcirc}{\bigcirc}}$ University Korean Medicine Hospital IRB's approval (2018-3). To make a diagnosis using CaPSPI, we decided the cut-points for the tool. Three professors of ${{\bigcirc}{\bigcirc}}$Korean Medical University conducted pattern identification diagnosis. The result is marked from 0 to 3, 0 is 'No', 1 is 'Slightly Yes', 2 is 'Yes' and 3 is 'Very Yes'. And if two or more professors' diagnoses are the same, we took the diagnoses as a diagnostic criteria. The decision of pattern by three experts converted to 0-1 scores in two ways. In "method 1", if the diagnosis was zero points, the score was 0 (have no such identification), and the rest was 1 (have such identification). In "method 2", if the diagnosis was zero or 1 point, the score was 0, and the rest was 1. After that, intraclass correlation was calculated for experts agreement. And logistic regression was conducted. A response variable was the results of the experts' diagnosis and an explanatory variable was the results of the pattern identification diagnostic tool. Results: The diagnosis of the three experts showed excellent concordance of more than 0.794 and showed a significant correlation with the diagnostic tool. Both 'Method 1' and 'Method 2' showed statistically significant effects with the diagnosis of 3 experts and the results of the diagnostic tool. The frequency of cumulative pattern identification diagnosis in 'Method 1' and 'Method 2' were found to be 578 occasions and 203 occasions, respectively. The average number of pattern held by participants in 'Method 1' and 'Method 2' were found to be 5.26 and 1.85, respectively. In both "Method 1" and "Method 2," the yield frequency of liver qi depression was the highest, and the frequency of kidney yin deficiency and liver-kidney yin deficiency was relatively high. Conclusions: Based on the above results, it is thought that, in diagnosis using CaPSPI of menopausal women, 'method 1' could be used for the health diagnosis and prevention, 'method 2' could be used for the pattern diagnosis. On the conclusion, CaPSPI is thought to be available for pattern diagnosis of menopause women.

Effect of forearm length applied on empirical models of maximum endurance time during isometric elbow flexion (등척성 팔굽 굽힘시 최대근지구력시간의 실증적 모델에 적용한 전완길이의 영향)

  • Sang-Sik Lee;Kiyoung Lee
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.16 no.5
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    • pp.338-346
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    • 2023
  • During isometric elbow flexion, forearm length should be an important factor to determine not only joint torque but also maximum endurance time (MET), when the forearm is perpendicular to the direction of the force. The purpose of this paper is to examine the effect of forearm length as an additional factor on empirical models of MET such as an exponential model and a power model during isometric elbow flexion. Thirty volunteers participated in our experiment to measure factor variables such as circumferences and lengths of their upper and lower arms. Their METs were measured according to the percent of maximum voluntary contraction intensity (%MVC). For the multiple linear regression model of ln(MET) using these measurements, significant variables could be observed in %MVC and forearm lengths (P<0.05). The empirical models were assessed by these models using forearm length as the additional factor. Mean absolute deviations (MAD) between the measured METs amd the two empirical models were about 19.4 [s], but MAD using models applied forearm lengths were reduced to about 16.2 [s]. The correlation coefficients and intraclass correlation coefficients were about 0.87, but those applied forearm lengths were increased to about 0.91. These results demonstrated that forearm length was a significant additional factor to the empirical model.

Correlation of responsiveness to pain intensity and functional status measurements after lumbar epidural steroid injection in patients with lower back pain

  • Park, Sun Kyung;Lee, Aeryoung;Cho, Suk Ju;Park, Sang Hyun;Yun, So Hui;Lee, Bang Won;Na, Changrock;Choi, Yun Suk
    • Journal of Medicine and Life Science
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    • v.19 no.1
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    • pp.20-25
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    • 2022
  • This study aimed to examine the changes in the Numerical Rating Scale (NRS), Oswestry Disability Index (ODI), and Roland Morris Disability Questionnaire (RMDQ) scores before and after epidural steroid injection (ESI) in patients with lower back pain, and the correlation between the three scales in patients with reduced scores on these scales. Patients completed the NRS, ODI, and RMDQ before and after receiving ESI. A paired t-test was performed to compare the mean scores obtained before and after ESI. The correlations between the scores were estimated by calculating the difference between the baseline and follow-up scores. Of the 49 patients, 37 completed both questionnaire assessments. Among them, 26 patients (70%) presented a post-ESI decrease in scores obtained on all three scales. The NRS score decreased from 6.81±1.91 points at baseline to 3.66±2.22 points at follow-up (P<0.0001); similarly, the ODI score decreased from 41.65±14.76 to 30.38±16.16 points (P=0.0025); and the RMDQ score decreased from 11.11±5.68 to 7.64±5.74 points (P=0.011). Of the 37 patients who completed the two questionnaires, 26 had reduced NRS, ODI, and RMDQ scores. The intraclass correlation coefficients between the NRS and ODI, NRS and RMDQ, and ODI and RMDQ scores were 0.7943, 0.6615, and 0.7182, respectively. The concordance correlation coefficients between the NRS and ODI, NRS and RMDQ, and ODI and RMDQ scores were 0.6020, 0.4938, and 0.5202, respectively. Among the measurements, the correlation between the NRS and ODI scores was the highest, and a moderate correlation was found between the scores obtained using the other instruments.

Reliability and validity of pelvic mobility measurement using a cushion sensor in healthy adults

  • Jung, Seung-Hwa;Kim, Su-Kyeong;Lee, Ji-Hyun;Choi, Soo-Ih;Park, Dae-Sung
    • Physical Therapy Rehabilitation Science
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    • v.9 no.2
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    • pp.74-81
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    • 2020
  • Objective: To prevent low back pain, an objective evaluation tool to evaluate pelvic mobility and exercise to improve the flexibility of the lumbar region is needed. The purpose of this study was to compare the results of pelvic mobility measurements using the Wii Balance Board (WBB) and Sensbalance Therapy Cushion (STC), evaluate the usefulness of the STC as a tool for measuring pelvic mobility. Design: Cross-sectional study. Methods: Fifty healthy subjects participated in this study. The subjects performed pelvic mobility range, proprioception, reaction time and reach of the arm using the STC. The pelvic movement parameter was measured two times to determine the intra-rater reliability. To measure the correlation between lumbar muscle tension and pelvic mobility, Myovision was used to measure tension of L4, L5 level erector spinae muscle. Correlations between measured variables were checked to determine the validity of the pelvic mobility assessment tool. Results: STC showed high test-retest reliability in pelvic tilt measurement and reaching task [intraclass correlation coefficients (3,1)=0.804-0.915]. The relationship between WBB and STC showed a significant positive correlation with the pelvic tilt and reaching task (p<0.05). Posterior tilt and erector spinae activation (Lt. L5) showed a significant negative correlation (p<0.05). Left, right tilt and erector spinae activation (L5) showed a significant negative correlation (p<0.05). Conclusions: This study confirmed the advantages of the STC and found efficiency as an objective measuring device of pelvic mobility.

Correlation Between Knee Muscle Strength and Maximal Cycling Speed Measured Using 3D Depth Camera in Virtual Reality Environment

  • Kim, Ye Jin;Jeon, Hye-seon;Park, Joo-hee;Moon, Gyeong-Ah;Wang, Yixin
    • Physical Therapy Korea
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    • v.29 no.4
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    • pp.262-268
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    • 2022
  • Background: Virtual reality (VR) programs based on motion capture camera are the most convenient and cost-effective approaches for remote rehabilitation. Assessment of physical function is critical for providing optimal VR rehabilitation training; however, direct muscle strength measurement using camera-based kinematic data is impracticable. Therefore, it is necessary to develop a method to indirectly estimate the muscle strength of users from the value obtained using a motion capture camera. Objects: The purpose of this study was to determine whether the pedaling speed converted using the VR engine from the captured foot position data in the VR environment can be used as an indirect way to evaluate knee muscle strength, and to investigate the validity and reliability of a camera-based VR program. Methods: Thirty healthy adults were included in this study. Each subject performed a 15-second maximum pedaling test in the VR and built-in speedometer modes. In the VR speedometer mode, a motion capture camera was used to detect the position of the ankle joints and automatically calculate the pedaling speed. An isokinetic dynamometer was used to assess the isometric and isokinetic peak torques of knee flexion and extension. Results: The pedaling speeds in VR and built-in speedometer modes revealed a significantly high positive correlation (r = 0.922). In addition, the intra-rater reliability of the pedaling speed in the VR speedometer mode was good (ICC [intraclass correlation coefficient] = 0.685). The results of the Pearson correlation analysis revealed a significant moderate positive correlation between the pedaling speed of the VR speedometer and the peak torque of knee isokinetic flexion (r = 0.639) and extension (r = 0.598). Conclusion: This study suggests the potential benefits of measuring the maximum pedaling speed using 3D depth camera in a VR environment as an indirect assessment of muscle strength. However, technological improvements must be followed to obtain more accurate estimation of muscle strength from the VR cycling test.