• The Korean Journal of Pharmacology
• /
• v.8 no.1
• /
• pp.67-75
• /
• 1972

Many studies on the mechanism of the inotropic action of cardiac glycosides have shown the possible intimate relationship between the mobilization of intracellular calcium and inotropic effect. Evidence obtained from recent studies suggests that cardiac glycosides may increase the intracellular $Ca^{++}$ concentration through the release of this ion from cellular or intracellular membrane. It seemed imperative to study the effect of ouabain on the interaction between mitochondria and $Ca^{++}$, because mitochondria are known to have a rather powerful $Ca^{++}$ pump mechanism which may have an important role on the regulation of intracellular $Ca^{++}$ concentration. The present investigations was made into the effect of ouabain on $Ca^{++}$ untake of mitochondria in the presence of ATP and its dependence on $K^+$ and $Na^+$ in the medium. The results are summarized as follows: 1. The rate of rise in the turbidity of superprecipitation was solely influenced by ionic strength of the medium, not by the species of ion, i.e. $Na^+$ or $K^+$. The higher ionic strength suppressed and the lower enhanced the rate of superprecipitation respectively. 2. No effect of ouabain was found on the rate of superprecipitation. 3. Mitochondria depressed the rate of superpretipitation, and the depressed rate of superprecipitation by mitochondria was reversed by ouabain, and the degree of this reversal was almost identical in $Na^+$ and $K^+$ medium. 4. $Ca^{++}$ uptake of mitochondria was inhibited by ouabain in the presence of ATP and the degree of inhibition showed the dose-response manner in terms of concentration of ouabain. 5. In the absence of ATP, mitochondria took or the $Ca^{++}$ in initial period but released it later. Such uptake and release of $Ca^{++}$ was not influenced by ouabain. 6. It is suggested that intracellular calcium mobilization by ouabain through the action upon the mitochondria was due to inhibition on ATP-dependent $Ca^{++}$ uptake by this agent, not to the action upon so called binding.

• Journal of Korean Medical classics
• /
• v.11 no.1
• /
• pp.224-307
• /
• 1998

The above study is based upon the Theory of Five Woon(Reasons) and Six Qi(Climates), namely Five dynamic Yin and Yang, the principle of five-six combination, the rules of ten periodically changing Woon and twelve periodically changing Qi, and its reference to the main chapters of the theory by several experts. After careful, comprehensive research and study, the followings are concluded. 1. The Theory of Five Woon and Six Qi controls all of the physical phenomena of the universe, yet it originates from Essence of the Sky that is replete and in constant motion within the abysmal expanse of the universe. So it is natural to claim that it is the Essence of the universe that is the source of the variety of phenomena in nature. 2. There is order of dynamics in the Essence and it is Yin Yang Five Movement and expressed by Five Woon and Six Qi. Therefore the Five Woon and Six Qi, which is the climatic changes of nature, is the basis and condition for all of the natural, physical occurrences including the organic phenomena of human beings. 3. Since the Sky embodied the number Five, and the Earth the number Six, Qi of the Sky itself is consequently Five Woon and Qi of the Earth itself is Six Qi. 4. In Sixty Repetition Intervals (Yuk Sip Kap Ja), the Sky took the number Six, designating the six times repetition of the ten Intervals of the Sky and the Earth chose the number Five, symbolizing five times recurrence of the twelve Intervals of the Earth. Though the number for the Sky is Five and the number for the Earth is Six, the two combine and interact in order for the Sky to exploit the number Six and for the Earth to use the number Five. This interplay implies the relationship of operation and principle of Yin in Yang and Yang in Yin. 5. There seems to be clear and intimate association between five dynamics, five bearings and five Qi' in nature and five organs, five stamina, and five emotions in physiological activities of human beings. Such an correlation apparently demonstrates the idea of climatic changes of the universe in balance among human beings, the Sky, and the Earth. 6. Because nature is of an endlessly dynamic organism itself, to have changes must mear there being movements. Thus the climatic changes in nature are the subsequent consummation of the interaction in mutual balance and unbalance of the rise and fall of the Five Woon and Six Qi. 7. The interpretation, by Chang Ji Chong of "Yin and Yang of the Sky are for birth and growth and Yin and Yang of the Earth for demise and interment" as an explanation that the first half is mainly for life and the second half for death, appears to be correct by his view that there is balance and harmony between the long and short and the strong and weak. 8. In addition to Three Yang and Three Yin, as attributes of the Intervals of the Sky and the twelve Intervals of the Earth, Five Woon and Six Qi are utilized in the annual observation of the perpetual changes of climates.

• Culinary science and hospitality research
• /
• v.15 no.3
• /
• pp.344-355
• /
• 2009

This study is to set up a hypothesis and a research model based on how much the relational benefits can affect customer satisfaction and long-term relationship with the theoretical and practical results of established precedent researches, to analyze the structural equation model on casual dining restaurant diners, to evaluate the research model and subsequently to provide marketing implications. First of all, social and psychological factors prove to be influential among relational benefits felt by diners-out. Secondly, customer satisfaction has influence on long-term commitment for a restaurant. In other words, the higher customer satisfaction level for a restaurant is, the stronger willingness a customer has to recommend or revisit the restaurant, as several precedent studies support. As demonstrated in indirect advantages, these social and psychological benefits felt by diners-out have mighty effects on long-term relationship orientation, and satisfaction levels prove to be an important medium which can make these influences. As a result, restaurant employees' attitude toward customers is the most important factor rather than economic benefits such as reduced price, free gifts and coupons are, since customers put social and psychological benefits forward like intimate terms with restaurant workers, a sense of stability, and a relief from uneasiness. Therefore, constant service education should be done from the start to cope with customers' demands fast and flexibly and increase customer satisfaction.

• Journal of Korean Academy of Nursing
• /
• v.22 no.4
• /
• pp.620-635
• /
• 1992

This study identified correlations between perceived family support and hopelessness in patients admitted to Neuro - surgical Intensive Care Units. The purpose was to enhance theoretical understanding of the relationships of these two variables. The subjects of this study were 51 patients admitted to N-lCU, at three general hospitals in Seoul. Data were collected by researcher in structured interviews from Aug. 12 to Oct. 13, 1992. The research tools were parts of the Moos Family Environment Scale and the Beck Hopelessness Scale. The general characteristic data were analyzed for frequency and percentage ; the hypothesis was tested by the pearson product Moment Correlation Coefficient. After normality tests by using Kolmogorov - Sminorvtest, and T- test, ANOVA and Mann-Whitney U test, Kruskal -Wallis test were used on the Family Support and the Hopelessness about general charcteristics. The results of the above analysis were as follows 1) The average family support score for the group was 63.61 (tool average 51) and item average was 3.74 (tool item average 3) : the family support score of this sample was higher than average. The average family cohesion score of family support was 35.25 (tool average 27) and item average was 3.91 (tool item average 3). The average family expression score of family support was 28.35 (tool average 24) and item average was 3.57 (tool average 3). In this sample, perceived family expression was lower than family cohesion. 2) The average hopelessness score was 45.88 (tool average 60) and item average was 2.29 (tool item average 3) : the hopelessness score of this sample was low in comparison to the average. 3) The hypothesis in this study was supported. The main hypothesis that the higher the perceived family support level, the lower the level Of the hopelessness, was Supported (r＝-.3869 p＝.003). The sub-hypothesis that the higher the perceived family cohesion level, the lower the level of hopelessness, was supported(r＝-.3688 p＝.004). The sub-hypothesis that the higher the perceived family expression level, the lower the level of hopelessness, was supported (r＝-.3068 p＝.014). 4) General characteristics of the objects related to family support were ‘economic status’(p＝.025) and ‘helping person’(P＝.044) : the higher the economic status, the greater the family support. When the patient identified the helping person as a spouse, family support was rated more highly. The only general characteristic related to family cohesion was ‘helping person’(p＝.041). No general characteristics were related to family expression. 5) The one general characteristic related to hopelessness was ‘education’(p＝.002) : the higher their education, the lower their hopelessness. For these ICU patients, were related perceived family support and hopelessness, and family expression level was low in comparison to family cohesion level. The perceived family support of these seriously ill patients in situational crisis may have influenced the patient's emotional reaction of hopelessness. This study concluded that nurses in the ICU confirm the family support of the patient, and involve the family as the most intimate support systems in the care of the patient to help reduce the patient's hopelessness.

• 한국HCI학회:학술대회논문집
• /
• 2008.02b
• /
• pp.239-244
• /
• 2008

We lead a life in our community, beginning a new relationship with a stranger or maintaining or stopping existing relationships. Relationships with others are sustained through social activities based on communication. Generally speaking, by exchanging feelings and information through communication, relationships are formed and continued, and strengthened through active communication As a result of the development of technologies and information technology over the recent 10 years, a mobile phone has stood as a communication channel, and now it has become such a universal, and highly intimate and important means of communication that almost all the Koreans use more often than wired phones. Today, people have their communication channel available for others, by using a mobile phone at any time and anywhere. Like this, mobile phones have been playing a key role in helping people maintain, repair and strengthen their personal relationship, but from the perspective of personal relationship management, they still remain as an aid to help communication, failing to provide a positive help for actual relationship management. This study was designed to provide services supporting user's personal relationship management, focusing on the use of mobile phones as a major tool of communication, aiming to enable users to understand current state of their relationship and make relationship management efforts, or communication behaviors, by informing who needs communication, on the basis of data on mobile phone calls. To this end, the study established a method to extract intimacy between users and callers and develop a prototype of services supporting personal relationship management, using relationship characteristics in terms of mobile communication.

• Journal of Hydrogen and New Energy
• /
• v.18 no.3
• /
• pp.230-237
• /
• 2007

Titania nanotube(TiNT) and CdS sol were synthesized by hydrothermal reaction under strongly basic condition and by precipitation reaction of $Cd(N0_3)_2$ and $Na_2S$ aqueous solutions, respectively. After preparing a series of CdS-TiNT composite films on $F:SnO_2$ conducting glass with variation of the mole ratio (r) of TiNT/(CdS+TiNT), their visible light absorption, photocatalytic activities for hydrogen production, and the photocurrent generation were examined. In general, this CdS-TiNT series showed lower photocatalytic activities and photocurrent generation under Xe light irradiation compared to their counterparts, i.e., CdS-$TiO_2$ particulate series. It appeared that TiNTs are not so effective photocatalyic material in spite of their larger specific surface areas compared to $TiO_2$ nanoparticles, because they indicate a poor crystallinity and less intimate interaction or contact with CdS particles owing to the tubular morphology and an easy agglomeration among themselves.

• Journal of Environmental Science International
• /
• v.20 no.12
• /
• pp.1585-1598
• /
• 2011

Emission reduction program for in-use diesel vehicles (ERPDV) has been enacted since 2004 over the Seoul metropolitan area, and diesel emission reduction is forced to fulfill this regulation. This study was performed to evaluate the ERPDV using $PM_{10}$ concentrations of both road-side monitoring and national background network during the period of 2004-2010. In order to assess the pure road emission, we first eliminated the long range transport effect by deducting the trend of annual national background concentrations from the road-side $PM_{10}$ concentrations, and then analyzed the time series of the resultant $PM_{10}$ concentrations over Seoul metropolitan area. The annual rates of variations of road-side $PM_{10}$ with the deduction of trend of background level show -3.2, +0.4, and -2.4 ${\mu}g/m^3$/year, in Seoul, Incheon, and Gyonggi province, respectively. There are steadily decreasing trend in Seoul with all of statistic parameters such as mean, mediam, 5%ile, 10%ile, 25%ile, 75%ile, 90%ile, and 95%ile concentrations. Incheon shows some fluctuations with positive with no significant trend, and Gyonggi province shows overall decreasing but not consistent. Student-t test shows 95% significant level of ERPDV effect in Seoul, but there exists no significant level greater than 90% in both Incheon, and Kyonggi province. Total annual averaged trend over the whole Seoul metropolitan area is estimated to lie in approximately $-2.9{\mu}g/m^3$/year in this study, implying the intimate involvement of ERPDV to a large extent. This is also suggesting that the further research cost-effectiveness of ERPDV with consideration of the long range transport process would be needed over the Seoul metropolitan area.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.33 no.3
• /
• pp.189-198
• /
• 2017

Purpose: This study aims to analyze the stress distribution of mandibular molar restoration supported by the implants with external hex and internal taper abutment connection design. Materials and Methods: Models of external connection (EXHEX) and internal connection (INCON) implants, corresponding abutment/crowns, and screws were developed. Supporting edentulous mandibular bony structures were designed. All the components were assembled and a finite element analysis was performed to predict the magnitude and pattern of stresses generated by occlusal loading. A total of 120 N static force was applied both by axial (L1) and oblique (L2) direction. Results: Peak von Mises stresses produced in the implants by L2 load produced 6 - 15 times greater than those by L1 load. The INCON model showed 2.2 times greater total amount of crown cusp deflection than the EXHEX model. Fastening screw in EXHEX model and upside margin of implant fixture in INCON model generated the peak von Mises stresses by oblique occlusal force. EXHEX model and INCON model showed the similar opening gap between abutment and fixture, but intimate sealing inside the contact interface was maintained in INCON model. Conclusion: Oblique force produced grater magnitudes of deflection and stress than those by axial force. The maximum stress area at the implant was different between the INCON and EXHEX models.

• The Korean Journal of Elementary Counseling
• /
• v.8 no.1
• /
• pp.95-107
• /
• 2009

The purpose of this study was to investigate the effect of social skill training on the class cohesiveness of Elementary School students. The experimental group received 12 times of the social skills training for 6 week period. And each training session which lasted for 40 minutes took place twice a week. A total of 59 5th grade students in randomly selected two classes of D Elementary School in N. Gyongsang participated in this study. They were divided into the two groups, again at random; an experimental group(N=30, Male=18, Female=12) and a control group(N=29, Male=15, Female=14). In this study, the class cohesiveness performance test reorganized into 20 items for the level of elementary students by Shin-suk Gang, was applied, after complemented. And, the collected data were analysed through SPSS 14.0. T-test was applied to find out the difference of the average between the experimental group and the control group and the average difference in the pre-and post-test of the experimental group alone, and to see whether the control group and the experimental group are homogeneous. The research design of this study is pre-and post-test control group design. The result of this study is as follows: The result of Independent t-test and Paried t-test on the cohesiveness score and sub-factor scores tells us that the experimental group which received the social skills training showed better achievement that deserves our attention compared to the control group. This result suggests that student's class cohesiveness(class atmosphere, mutual trust, morale, a sense of unity, communication) is positively affected by the social skill training. Accordingly, social skill training which develops class cohesiveness can be an effective strategy for elementary school students to make them more intimate and cooperative with their classmates.

• Journal of the Korean School Mathematics Society
• /
• v.15 no.1
• /
• pp.81-108
• /
• 2012

One of the keyword in every nation's recent educational policy is key competencies. Considering national competitiveness originating from educational competitiveness, educational policy has been driven to identify key competencies and realize them through school education. Within this context some countries have developed competencies-based curriculum and discussed ways to relate key competencies and subject matter areas. However, there have been few researches on how to reflect or integrate key competencies into subject matter areas. Because of this reason, the ways to incorporate and integrate key competencies into three subject areas including mathematics were investigated. The recent trends of curriculum, teaching and learning, and assessment of domestic and foreign cases were explored by the subject of one Korean international middle school, one British foreign school in Seoul, one French foreign school in Seoul, and four middle schools in New Zealand. To establish competencies-based school education, there should be intimate connection system among curriculum, teaching and learning, assessment, and teacher education. Through analysis of domestic and foreign cases, some conclusions regarding how these aspects have changed with the emphasis of key competencies were drawn. In this paper, through classroom observation and teacher interview, a case of the competencies-based mathematics lessons of one French foreign school was investigated. As a result, summaries and recommendations related to ways to improve subject teaching and teacher education in light of key competencies were presented. In these recommendations, the ways to reconstruct subject-based curriculum, the content-specific teaching and learning, and educational assessment were included.