• Title/Summary/Keyword: Intervention studies

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A Systematic Review of Korean Medicine for Non-Alcoholic Fatty Liver Disease (비알콜성 지방간질환의 한방치료에 대한 체계적 문헌고찰)

  • Lee, Yu-ri;Cho, Na-kyung;Choi, Hong-sik;Kim, Seung-mo;Kim, Kyung-soon
    • The Journal of Internal Korean Medicine
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    • v.40 no.1
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    • pp.13-37
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    • 2019
  • Objectives: The purpose of this study was to assess the effects of Korean medicine for non-alcoholic fatty liver disease (NAFLD). We analyzed the result of randomized controlled trials (RCTs) that applied Korean medicine to NAFLD patients through meta analysis and systematic review. Methods: The key question was to the effects of Korean medicine for NAFLD patients according to the PICO-SD (participants, intervention, comparison, outcome, study design) and we included only RCTs. We searched 10 databases including NDSL, KMBASE, KISS, KISTI, KoreaMed, Koreantk, OASIS, Cochrane, Pubmed, EMBASE without a language restriction. We assessed risk of bias by Cochrane group's Risk of Bias tool. Results: The finally selected 12 RCTs were analyzed. Total number of participants was 1189 (male 719, female 470) as 684 and 505 in the oriental medicine group (i.e. herbal drugs, acupuncture, acupoint embedding therapy) and control group (conventional drugs, placebo), respectively. The meta analysis results of examining 7 RCTs comparing the therapeutic efficacy of herbal medicine with that of Western medicine showed statistically significant (p<0.05) differences in the efficacy evaluation, liver function test results, blood lipids, and TNF-${\alpha}$. Furthermore, the meta analysis results of investigating 3 RCTs comparing the therapeutic efficacy of herbal medicine with that of a placebo showed statistically significant (p<0.05) differences in the liver function test results, blood lipids, and waist circumference. Conclusions: The research showed that Korean medicine for NAFLD can be effective treatment. But more studies are required to enhance the level of evidence and we should report on safety.

Exploring the Latent Classes in Students' Executive Function Difficulty by Mother and Teacher: Multivariate Analysis across School Adaption and Academic Performance (초등학생의 집행기능곤란에 대한 어머니와 담임교사 평정에 따른 잠재집단 탐색 및 학교적응, 학업수행 차이 검증)

  • Yeon, Eun Mo;Choi, Hyo-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.6
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    • pp.38-47
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    • 2019
  • The purpose of this study was to identify latent classes in executive function difficulty of first graders depends on evaluations from their mother and teacher and to investigate how its related with their school adaption and academic performance in second grade. Based on the model of the latent profile analysis, the 8th and 9th wave data from Korean Children and Youth Panel Survey were analyzed. The results of this study were as following. First, results showed that there were three types of latent classes in the executive function difficulty depend on evaluations from their mother and teacher: 'low executive function,' 'students who were highly evaluated by mother,' and 'students who were highly evaluated by teacher.' Second, students' executive function difficulty had a direct effect on the students' school adaption and academic performance in their second year of school. Especially students who were evaluated as having the lowest executive function difficulty showed significant higher means than students who were evaluated higher by mother and teacher. This study emphasized the importance of multiple evaluation in students' executive function difficulty to provide an educational intervention.

Characteristics of Clinical Trials in Korea for Atopic Dermatitis - Focus on ClinicalTrials.gov Registered Clinical Trials - (식약처 승인 아토피 피부염 의약품 국내 임상 시험의 특성 - ClinicalTrials.gov 등록 임상시험을 중심으로-)

  • Hwang, Mi-Lee;Ahn, Jae-Hyun;Jea, Ha-Kyung;Kim, Soo-Young;Jung, Hyun-A
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.2
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    • pp.68-93
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    • 2019
  • Objective : This study summarized the characteristics of clinical trials for atopic dermatitis medicines approved by the Ministry of Food and Drug Safety(MFDS). This study may be a reference for the design of clinical trials of atopic dermatitis herbal medicine treatment which may be carried out later. Method : The characteristics of the clinical trial were analyzed for clinical trials registered with ClinicalTrials.gov, CRIS, and the Korea Health Industry Development Institute among the clinical trial approval statuses posted on the website of the MFDS. Result : 1. Clinical trial drugs were developed in various formulations such as oral medicines, injections, dermatologic agents, and similar proportions. Relatively little clinical trials were found for herbal medicine. 2. In the control evaluation test, most of the treatments for the control group were performed with placebo using Vehicle. 3. In most clinical trials, one intervention group was in the form of a parallel assignment with only one treatment. 4. The age of the subjects was 11 out of 28 studies including minors, and clinical trials targeting minors were also found to be significant. 5. In the case of atopic dermatitis, the cases of subacute chronic or atopic dermatitis more than 6 months or more than 1 year were often used. 6. Most clinical trials were divided into mild to moderate atopic dermatitis or moderate to severe atopic dermatitis. The SCORAD index, EASI, IGA, BSA, and NRS were used as the evaluation criteria. 7. Regulations for the drugs used prior to the trial period for the treatment of atopic dermatitis vary somewhat from one clinical trial to another. 8. IGA was used most often as a primary efficacy tool, and SCORAD index, EASI, and NRS were also used.

Effects of State-Anxiety and Dyadic Adjustment on Pregnant Women's Pregnancy Stress (임부의 상태불안, 부부적응이 임신스트레스에 미치는 영향)

  • Hwang, Ran Hee
    • Journal of Digital Convergence
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    • v.17 no.5
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    • pp.225-233
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    • 2019
  • The purpose of this study was to investigate state-anxiety, dyadic adjustment and pregnancy stress in pregnant women and to identify factors influencing pregnancy stress. Data were collected 158 pregnant women. Data were analyzed using t-test, ANOVA, Scheffe's test, Pearson's correlation coefficient, stepwise regression analysis. There was statistically significant difference in state-anxiety on variable such as age. There were statistically significant difference in dyadic adjustment on variables such as education, religion, income. There was not statistically significant difference in pregnancy stress on variables. Pregnancy stress was positively correlated with state-anxiety. Pregnancy stress was negatively correlated with dyadic adjustment. State-anxiety was negatively correlated with dyadic adjustment. Factor influencing pregnancy stress was state-anxiety, which explained 25.1%. Findings provide useful information for further studies in pregnancy stress of pregnant women. Therefore, to reduce pregnancy stress of pregnant women, it is necessary to standardized nursing intervention program.

Development of Growth Model Using Ecological Momentary Assessment: Based on Senior Vitality Quotient (생태순간평가를 이용한 성장모형개발: 노년 활력 지수를 활용하여)

  • Jeon, Hee Jin;Song, Hye Sun;Lee, Ji Hyun;Park, Kiho;Choi, Kee-Hong;Seo, Dong Gi
    • Journal of the Korea Convergence Society
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    • v.12 no.5
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    • pp.313-326
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    • 2021
  • This study was to introduce ecological momentary assessment and show how to apply it to real-world research. As preliminary study for sustainable development, the result explained growth model using senior's longitudinal data and suitability of multi-level model in EMA data with regression analysis. The total variance of dependent variable was determined through a base model with only intercept and approximately 47% of total variance was caused by individual differences and 53% by time point differences. Second model was used to verified that each individual has a different effect on the senior vitality and effect on time was not significant. This is because it is the result of a preliminary stage where treatment is not involved and there is no significant change in process of collecting EMA data without external intervention. Third model that add gender as an independent variable showed significant change in both time and gender. Finally compared the PRD for each model and found models that without gender variables fit the data more effectively. This suggests that studies dealing with longitudinal data such as EMA data should adopt multi-level model that can measure individual characteristics, taking into account respondents' time and context.

A Convergence Structural Model for Self-leadership among Female Freshmen in Health Majors Studying TOEIC (TOEIC을 학습하는 보건계열 신입 여대생의 셀프리더쉽에 관한 융복합적 구조모형)

  • Hong, Soo-Mi;Bae, Sang-Yun
    • Journal of Digital Convergence
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    • v.17 no.11
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    • pp.269-278
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    • 2019
  • This study ascertained convergent influence on self-leadership and its association with self-competence, self-efficacy and locus of control among female freshmen in health majors studying TOEIC. Data collection was carried out using a self-administered questionnaire from April 29, 2019 to May 10, 2019 and the target was randomly selected 201 female freshmen in health majors in TOEIC class from college located in J city. Self-leadership was positively correlated with self-competence, self-efficacy and locus of control. The covariance structure analysis showed that the higher self-competence, the higher self-efficacy and the lower locus of control tend to increase self-leadership. The results of the study indicate that the efforts, to increase self-competence and self-efficacy, to decrease locus of control, are required to improve self-leadership of female freshmen in health majors studying TOEIC. These results are expected to be used for educational counseling and intervention efforts to enhance self-leadership among female freshmen in health majors studying TOEIC. In future studies, further research on additional factors affecting self-leadership is needed.

Latent Profiles of Perceived Changes and Difficulties in Single-Parent Family: Focusing on Depression Level (한부모가 된 후의 변화 및 어려움에 대한 잠재프로파일 분석: 우울 수준의 차이를 중심으로)

  • Yeon, Eun Mo;Choi, Hyo-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.550-557
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    • 2021
  • This study examined the latent groups regarding the changes and difficulties after becoming a single parent and analyzed the differences in the backgrounds and depressive levels according to each group. The data of 2,500 single parents from the 2018 Single Parent Family Survey were analyzed by Latent Profile Analysis (LPA). LPA indicated four-profile groups: 1) parenting stability group, 2) normal group, 3) economic stability group, and 4) potential-risk group. Its determinants included gender and economic status, including government funding type and employment status rather than academic status. Specifically, female single parents with an unemployed or low-income support household were more likely to be linked to the potential-risk group. In addition, the potential-risk group showed a higher depressive level than the parenting stability group, normal group, and economic stability group. The significance of this study is that distinguished intervention based on the characteristics of each group can promote the effectiveness of single-parent family support policy.

Relationship between Suppression Strategy of Emotional Expression and Posttraumatic Growth: Serial Multiple Mediating Effects of Self Disclosure on Traumatic Event and Social Support (정서표현억제전략과 외상후 성장의 관계: 외상사건에 대한 자기개방과 사회적 지지의 순차적 다중매개효과)

  • Sull, Keon-Hye;Kim, Min-Hee
    • The Journal of the Korea Contents Association
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    • v.21 no.6
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    • pp.392-403
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    • 2021
  • The purpose of this study was to examine the effect of emotion regulation strategy on posttraumatic growth and to confirm serial multiple mediating effects of self disclosure on a traumatic experience and social support in relationship between suppression strategy of emotional expression and posttraumatic growth. A survey was conducted for adults over the age of 18. Data of 663 adults (222 men, 441 women) were analyzed. According to analysis by using SPSS Process Macro, the less suppression strategy of emotional expression was used, the higher posttraumatic growth was. Simple mediating effect of self disclosure was confirmed between suppression strategy of emotional expression and posttraumatic growth. Serial multiple mediating effects of self disclosure and social support were shown in relationship between suppression strategy of emotional expression and posttraumatic growth. It means that the more people who use less suppression of emotional expression as their emotion regulation strategy, the more they disclose on their traumatic experience, then, they will receive emotional comfort and support from the people around, finally reaching posttraumatic growth. The importance of self disclosure and social support on posttraumatic growth was verified. Counseling intervention method was suggested for involuntary clients who usually suppress emotional expression, to enhance their posttraumatic growth. Lastly, significance and limitations of this study were suggested for follow-up studies.

Effects of Music Therapy on Cognitive function and Agitation, Anxiety and Depression in Dementia Elderly: a Systematic Review and Meta-analysis of Randomized Controlled Trials (음악요법이 치매노인의 인지기능, 초조행동, 불안 및 우울에 미치는 효과: 체계적 고찰 및 메타분석)

  • Chai, Gong Ju;Lee, Mi-Kyung;Nam, Eun Sook;Lee, Ho Yeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.1
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    • pp.520-530
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    • 2021
  • Objectives: This study aimed to identify the effects of music therapy on cognitive function, agitation, anxiety and depression in the elderly with dementia. Method: A comprehensive literature search was performed on PubMed, EMBASE, Cochrane Library, CINAHL, Web of Science, Google scholar and PsycINFO, for the period 2010 to 2019. In the meta-analysis, the standardized mean difference (Hedges' g) and 95% confidence interval were calculated as summary measure, and the random effect model and inverse variance method were applied using the RevMan 5.4 program. A total of 13 studies were included; all were determined to be acceptable, based on the Cochrane collaboration's tool for assessing risk of bias. Results: The effect size (Hedges' g) was 0.31 (95% CI: -0.02, 0.65) for cognition and -0.03 (95% CI: -0.17, 0.11) for agitation behavior as the primary outcomes, and 0.61 (95% CI: -1.17, -0.05) for anxiety and -0.44(95% CI: -0.88, 0.00) for depression as the secondary outcomes. Subgroup analysis by type of music intervention revealed that combined music therapy has a significantly increasing beneficial effect on cognition of dementia patients (g=0.45[95% CI: 0.03, 0.87]). Conclusion: Music therapy was determined to exert beneficial effects in reducing anxiety and depression, and combined music therapy demonstrated improved cognitive functions in elderly patients with dementia.

Longitudinal Influence of Chronic Intimate Partner Violence on Suicidal Ideation among Korean Married Woman (한국 기혼 여성에서 만성적인 친밀한 관계에서의 폭력이 자살사고에 미치는 장기적인 영향)

  • Park, Hyein;Lee, Jinhee;Han, Jaehyun;Min, Seongho
    • Korean Journal of Psychosomatic Medicine
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    • v.28 no.2
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    • pp.108-115
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    • 2020
  • Objectives : This study looked at the effects of chronic IPV on suicide ideation among married women in the country. Methods : This study used data from the five-year-old Korea Welfare Panel and analyzed using questions about verbal and physical violence, depression and suicide ideation that were investigated every year. Age, education, and economic levels, drinking, religion, chronic disease, satisfaction with family relationship, satisfaction with social relationship, were included as variables. Results : The five-year cumulative score of verbal violence had a statistically significant effect on the depressive symptom, and the relative risk was 1.180. The relative risk of five-year-old cumulative score of verbal violence in suicidal ideation was 1.276, and it was also significant even if they exclude the effects of depressive symptom. On the other hand, the five-year cumulative score of physical violence was found to have no significant impact on suicide ideation if they excluded the effects of depressive symptom. Conclusions : Unlike previous studies, this study found that chronic verbal IPVs increase suicide ideation, even though they do not contain effects of depression. Such findings suggest that intervention in IPV in married women may help reduce the nation's suicide rate.