• Title/Summary/Keyword: Intervention studies

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Pharmacological Action of Radix Scutellariae on Nicotine-Induced Locomotor Activity and C-Fos Expression in Rats. (황금의 니코틴 약물투여에 의한 유전자 발현과 행동적 변동에 미치는 약리작용)

  • Lee Bom-Bi;Chae Youn-Byoung;Kwon Young-Kyu;Yang Chae-Ha;Kim Mi-Ryeo;Kim Kwang-Jung;Seo Yong-Min;Kim Jang-Hyun;Hahm Dae-Hyun;Lee Hye-Jung;Pyun Kwang-Ho;Shim In-Sop
    • The Journal of Korean Medicine
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    • v.26 no.3 s.63
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    • pp.1-12
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    • 2005
  • Objectives : Substantial evidence suggests that reinforcing effects of nicotine can be mediated by the mesolimbic dopaminergic system. It has been shown that repeated injections of nicotine produce an increase in locomotor activity and expression of the immediate-early gene, c-fos, in the dopaminergic target areas. Herbal medicine as a therapeutic intervention has been widely used for the treatment of mental dysfunction. Many studies have shown that Radix Scutellariae (RS) can affect the biochemical balance in the central nervous system. Tn order to investigate whether RS has an influence on nicotine-induced behavioral sensitization, we examined the effect of RS on nicotine-induced locomotor activity and c-fos expression in the striatum and nucleus accumbens utilizing the fos-tike immunohistochemistry (FLI). Methods : Male SD rats received RS (200mg/kg, i.p.) 30min before repeated daily injections of nicotine (0.4mg/kg, s.c.) for 7 days. This was followed by withdrawal for 3 days and one challenge for 1 day. Results : System challenge with nicotine produced a much larger increase in locomotor activity and accumbal FLI. Pretreatment with RS significantly inhibited nicotine-induced locomotor activity and FLI in the striatum and nucleus accumbens. Conclusions : These results demonstrate that reduction in locomotor activity by RS may be reflected by reduction of dopamine release and postsynaptic neuronal activity in the striatum and nucleus accumbens. Our results suggest that RS may have therapeutic effect on nicotine addiction.

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Effects of Limited Hyperextension at Knee Joint Using Limited Motion Knee Brace on Balance, Walking in Patients with Hemiplegia (슬관절 움직임 제한 보조기를 이용한 슬관절 과신전 제한이 편마비 환자의 균형과 보행에 미치는 영향)

  • Lee, Eun-Hyuk;Min, Kyung-Ok;Lee, Kang-Sung
    • The Journal of the Korea Contents Association
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    • v.10 no.3
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    • pp.258-265
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    • 2010
  • The purposes of this study was to determine the effects of limited hyperextension at knee joint using Limited Motion Knee Brace on balance and walking in patients with hemiplegia. The subjects of this study were 20 post-stroke hemiplegic patients admitted. Subjects were randomly assigned to either experimental group (Limited Motion Knee Brace group) or control group (manual restriction group). Both groups received traditional physical therapy intervention. The effects of each therapeutic method were evaluated by measurements of gait ability assesment, Berg balance scale (BBS), 10-meter walk speed (10MWS), Timed Up & Go (TUG) Test. The results of this research were as followings: (1) After treatment, there were significant BBS scores differences in both experimental and control group compared with pre-treatment(p<0.05). (2) After treatment, there were significant TUG test scores differences in both experimental and control group compared with pre-treatment (p<0.05). (3) After treatment, there were significant 10MWS differences in both experimental and control group compared with pre-treatment (p<0.05). (4) There were significant BBS scores differences in third and fourth week between experimental and control group (p<0.05). It was concluded that Limited Motion Knee Brace was effective for improving balance and for reducing fatigue for experimental group. Therefore, further studies are required to investigate the effect of knee orthosis for improving balance and walking in patients with hemiplegia.

The Analysis of Exercise Therapy in Nursing Research (운동중재에 관한 국내 간호학 논문 분석)

  • 전점이
    • Journal of Korean Academy of Nursing
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    • v.30 no.2
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    • pp.319-330
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    • 2000
  • This study is aimed at analyzing the trend of research on the use of exercise in nursing research, through suggesting directions for future research and implementation of the various exercise therapies. Research studies were taken from dissertations and theses selected from the Academic Society Journals of nursing science, Journals from universities, medical and nursing schools, research institutes in various universities, the Central Journal of Medicine, and the New Medical Journal. The research published between 1970 and 1997 in Korea were analyzed, 51 research were selected. The research are analyzed according to: published time, source of the research, research design, subjects, sample size, dependant variables, exercise therapy, and effect of exercise therapy. The results were as follows: 1. Research on exercise therapy increased rapidly in the 1990's. At this time, 88.2% of research was published. 2. Research areas included: 54.9% non- degree research, 27.5% Doctoral theses, and 17.6% Master's theses. 3. The experimental design included: 66.7% non- equivalent control group pre-test/ post-test design and 29.4% one group pre-test/post- test design. 4. Out of the Subjects: 52.9% were patients with various health problems, and 47.1% were healthy individuals. 5. Sample size included: 52.9% with above 31 subjects, 11.8% with 11~15 and 26~30. 6. Exercise therapy was analyzed by type, intensity, frequency, duration, and period. 1) The Types: Aerobic exercise at 60.8% was the most common, active exercise for muscle strengthening and building made up 21.6%. 2) Exercise with 40~65% intensity comprised 25.5%, 70~85% with 7.8%, and no description of the intensity was 66.7%. 3) Frequency of 3~5 per week was the most common at 78.4%. 4) Duration: 15~60 minutes was the most common length of time at 76.5%. 5) Periods: More than 5 weeks at 82.3% were the most common in their categories. 7. Dependant variables: Psychological response was measured as a dependant variable in 92.2%, Cardio-pulmonary function 88.2%, Body Composition was 86.3%, Physical Response was 60.8%, Lipid Metabolism was 58.8%, Physical Strength was 49.0%, Glucose Metabolism was 25.5%, Activities of Daily Living was 17.6% and others added to be 3.9%. 8. The effect of Exercise Therapy was categorized into 'positive', 'partially positive', and 'no effect' according to dependant variables: Having a positive effect - Glucose Metabolism (93.3%), Physical Response (85.0%), Activities of Daily Living (81.8%), Psychological Response (71.6%), Lipid Metabolism (67.6%), Cardio- pulmonary Function (63.6%), Physical Strength (68.1%), and Body Composition (56.4%). The following suggestions can be made on the above findings: 1. Research findings on Exercise Therapy as a Nursing Intervention need to be described by their elements of type, intensity, frequency, duration and period. 2. Toproperly study the positive effects of Exercise Therapy, there needs to be ⑴ appropriate research design, ⑵ selection criteria for the subjects ⑶ contents of exercise prescription to individuals or groups ⑷ measurement criterion for the dependent variables. 3. Meta-analysis on exercise therapy also needs to be done to analyze and integrate the various results.

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The Diagnosis and Treatment of Anterior Openbite Malocclusion (전치부 개방교합의 진단과 치료)

  • Chang, Young-Il;Moon, Seong-Cheol
    • The korean journal of orthodontics
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    • v.28 no.6 s.71
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    • pp.893-904
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    • 1998
  • There are varieties of severe malocclusions, which can be treated orthodontically, but with a great deal of effort. Anterior openbite, in particular, is one malocclusion thought to be more difficult to treat, and therefore, most of them have to be corrected by means of surgical intervention. To solve these problems, numerous studies pertinent to treatment modalities have been introduced with controversies on the effectiveness of treatment. Suggested treatment modalities for anterior openbite are based directly or indirectly on the neuromuscular and morphological features and on the etiologic and/or the environmental factors. Even though the vertical relationship of the face is increased due to the growth variation, the normal occlusal relationship can be achieved by the adequate dentoalveolar compensatory mechanism, but in the case of inadequate or negative dentoalveolar compensation, openbite is likely to be present. If the skeletal dysplasia is too severe to be solved by orthodontic treatment alone, combined treatment with surgery should be done to restore the function and the esthetics of the orofacial complex. In many cases, however, orthodontic alteration of the dentition pertinent to the given skeletal pattern with the proper diagnosis and treatment planning can bring satisfactory results. The treatment changes with the Multiloop Edgewise Archwire(MEAW) therapy occurred mainly in the dentoalveolar region and showed a considerable similarity to the natural dentoalveolar compensatory mechanism. In other words, the MEAW technique allows orthodontists to produce the natural dentoalveolar compensation orthodontically. Even if an openbite is corrected by the orthodontic dentoalveolar compensation suitable for the skeletal pattern, relapse may still occur by the persisting etiologic factors which originally prohibited the natural dentoalveolar compensation. The etiologic factors should be determined at the time of initial diagnosis and should be controlled during treatment and retention.

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Development of morning bread fortified citrus peels powders and its evaluation of biological activity by human trial (귤피가루를 첨가한 모닝빵 개발 및 인체시험을 통한 생리활성 효과 평가)

  • Lee, Ha-Neul;Park, Tae-Sun;Yu, Ok-Kyeong;Byun, Moon-Sun;Cha, Youn-Soo
    • Journal of Nutrition and Health
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    • v.49 no.3
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    • pp.144-152
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    • 2016
  • Purpose: This study was conducted in order to develop morning bread using powdered citrus peels and to examine the effect of its several biological activities for 12 weeks in overweight adults ($$BMI{\geq_-}23$$) living in dormitories of Chonbuk National University. Methods: Control bread was prepared using the same formula except for replacing the wheat flour with 3% citrus peel powder. Subjects were classified according to two groups: Intake group of 3% citrus peel powder fortified morning bread (n = 30) and general morning bread (n = 30). Results: The results of our study showed no significant effects of citrus peel powdered morning bread on anthropometric indices and biochemical characteristics among overweight adults. Despite the slight reduction in total-cholesterol, LDL-cholesterol, GOT, and GPT (p < 0.05), no significant differences in changes of these values were observed between the two groups. Conclusion: The short duration of our intervention might have resulted in the lack of any significant effect. Therefore, conduct of further studies with longer duration is warranted in order that the results from this study can be utilized as a basis for the development of food products with citrus peel powder.

Adaptation Experiences of Male Students in the Department of Nursing (간호학과 남학생들의 학과 적응 경험)

  • Kim, Seong-Hyuk;Kim, Soon-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.8
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    • pp.113-126
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    • 2016
  • The main purpose of this study is to provide the necessary information for educational intervention by discovering the components and factors related to the adaptation experience of male students in the department of nursing. The participants were seven male nursing students. Data were collected from in-depth interviews, and the results were analyzed by the Giorgi's phenomenological analysis method. The main components of adaptation experience of participants were summarized into four categories: 'hopes and expectations for the future careers,' 'conflicts and wandering under realistic issues,' 'compromise and emotion management,' and 'efforts for self-growth.' Causative, accelerative, and recursive characteristics were shown among these components. The adaptation process was structured in the temporal context. The results suggest that for amicable adaptation, internal controls, such as 'improving willpower,' 'inspiring solid career awareness,' and 'selecting adaptation strategy' were all critical. Moreover, the support of families, relatives, college seniors, and department professors were revealed as the factors that help in the adaptation experiences. Based on the results, further studies are required to identify the dropout rates by maladaptation of male nursing students, and analyze possible factors that contribute to dropout and maladaptation. In addition, it is necessary to construct various coping methods and practical support systems, as well as to develop appropriate educational programs.

Relationship between Digital Informatization Capability, Digital Informatization Accessability and Life Satisfaction of Disabled People: Multigroup Analysis of Perceived Social Support Network (장애인의 디지털정보화역량, 디지털정보화활용 수준, 일상생활만족도 간 관계: 지각된 사회적 지지망 수준에 따른 다집단 분석)

  • Yeon, Eun Mo;Choi, Hyo-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.636-644
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    • 2019
  • The purpose of this study is to explore practical intervention strategies by identifying the relationships among digital informatization capacity, level of digital informatization accessability and life satisfaction of disabled people and to determine differences among these relationships depending on perceived level of social support networks. The participants were 1,639 disabled people from the 2017 digital information gap survey and the results, based on structural equation modeling and multi-group analysis, are as follows. First, digital informatization capacity has a positive influence on the level of digital informatization accessability(β=.65), and life satisfaction(β=.08). The level of digital informatization accessability also has positive influence on life satisfaction(β=.44). Second, the analysis result of the mediated effects of digital informatization accessability level between digital informatization capacity and life satisfaction was significant at a level (β=.29) even greater than the direct effect of digital informatization capacity on life satisfaction. Third, digital information capacity and digital informatization accessability have an influence on life satisfaction regardless of their perceived level of social support. The findings suggest that creating online environments where disabled people can enjoy leisure, culture, and social interaction with high accessibility and utility are as important as providing education for improving their digital informatization capacity.

Comparison of Activities of Daily Living Differences with Dementia Stage (치매 단계별 일상생활수행능력의 차이 비교)

  • Jang, Jong-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.12
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    • pp.557-563
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    • 2017
  • This study aims to obtain information about the ADL and I-ADL functions of people with dementia living in the community and nursing care facilities regarding their dementia stages for the purpose of supporting occupational therapists working in dementia care centers. The information was collected from 100 people with dementia living in the community and 100 people with dementia staying in care facilities from October 1 to November 20, 2015. 15 facilities participated in this study, including nursing homes, day care centers, health centers, geriatric hospitals and metropolitan dementia centers. All of the assessors were trained in the use of the instruments, ADCS-ADL, S-IADL, S-ADL and MMSE-K, by the researcher before conducting any evaluations or interviews. In order to compare the differences in the levels of ADL according to the dementia stage, an analysis was made via the post-hoc test after conducting a one-way ANOVA. An analysis of the residence type and dementia stage was made through the independent t-test. The comparison of the level of ADL between the people with dementia living in the community and those living in nursing homes showed differences in the moderate level of dementia for all items of the I-ADL and ADL (p<.01). The post-hoc test showed that there is a difference among the minimum, mild, and moderate levels. When the differences in ADL according to the residence type were examined, there were no significant differences in any of the stages (p>.05). Considering these results, it may be critical to identify the changes in the I-ADL rather than those in the ADL for the outcome index when conducting future intervention studies on dementia.

Longitudinal Transition of Adolescents' Psychological Character Profiles and its Predictors in Multicultural Families (다문화 가정 청소년의 심리적 특성 잠재프로파일의 종단적 변화 및 영향 요인)

  • Yeon, Eun Mo;Choi, Hyo-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.3
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    • pp.164-172
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    • 2020
  • This study investigated the longitudinal transition of adolescents' psychological character profiles, which includes self-esteem, acculturative stress, depression, and social withdrawal, and the predictive effects of parental efficacy, families' support, and friends' support in multicultural families. The sample consisted of 1,188 adolescents in elementary school, who were re-examined in three years, when they were in middle school from the part of waves 2 and 6 of the Multicultural Adolescents Panel Study. A latent profile analysis identified three distinct profiles of psychological character among adolescents in elementary school and middle school: stable, social withdrawal, and unstable. As compared to elementary school, adolescents' psychological characteristics stayed stable and played critical roles on the latent classes. Parental efficacy, and supports from family and friends played critical roles on the latent classes. Specifically, as adolescents perceived full of supports from friends, they were more likely to make transitions to the stable group. Implications for intervention in multicultural families are discussed.

The effects of emotional labor of dental hygienist on the job stress, anxiety and sleep (치과위생사의 감정노동이 직무스트레스와 불안, 수면에 미치는 영향)

  • Park, Hye-Young;Jang, Gye-Won;Lee, Gung-Hwa;Lee, Min-Kyung;Lee, Geong-Won;Iim, Yong;Lee, Jong-Ryol;Kim, Hye-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.17 no.3
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    • pp.449-463
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    • 2017
  • Objectives: The objective of this study was to identify the relationship between emotional labor and occupational stress of the dental hygienists, and the effects of emotional labor on their occupational stress and health problems including depression, anxiety and sleep. Methods: The survey was conducted using the questionnaires about dental hygienists' working in medical institutions in Busan, Gyeongsangnam-do from August 19th and October 7th, 2016. Total of 225 participants were selected for data analyses. Frequency analysis, t-test, ANOVA, Pearson's correlation coefficient analysis, and regression analysis were conducted using SPSS Windows ver. 21.0 program(SPSS Inc., Chicago, IL. USA). Results: The analysis of the factors affecting emotional labor, occupational stress, anxiety, and sleep by participants' characteristics showed that those with higher education level, work position and annual salary had higher emotional labor. In addition, participants who worked 5 days every other week and were responsible for patient consultation had higher emotional labor. The analysis of correlations among emotional labor occupational stress, anxiety, and sleep showed positive correlations between emotional experience and emotional expression, occupational stress and emotional expression, and anxiety and emotional expression. On the other hand, negative correlation was found between anxiety and emotional experience. Regression analysis was conducted to examine the effect of emotional labor on job stress. Emotional labor was a factor affecting job stress and anxiety. Conclusions: In order to improve emotional control and vulnerability to stress among dental hygienists, intra-organizational training opportunities and mental health care strategies are needed. Additional broad-based studies are required to identify the factors affecting the occupational stress and emotional labor and to develop relevant intervention measures.