• The Journal of the Korea Contents Association
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• v.18 no.4
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• pp.586-600
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• 2018

The purpose of this study attempted to collect basic data for development of an integrated self-management program for cancer survivors who completed cancer treatment. Self-management programs are divided into symptom management and physical activity management. Symptom management includes fatigue, sleep disturbance, pain, depression and anxiety. PubMed, CINAHL and EMBASE were used for searching guidelines. Based on the guideline quality evaluation, the final 8 guidelines were analyzed. The structured table was used to extract the screening subjects, timing, contents, subjects for comprehensive assessment and contents, and summarized contents related to the physical activity and exercise in non-pharmacological approach. As a result, after the completion of cancer treatment, all cancer survivors should be screened regularly using reliable and validated tools. In the case of fatigue, physical activity was recommended as the primary intervention, but it was recommended for other symptoms as adjuvant therapy. Therefore, Cancer survivors should be encouraged to be active in their physical activity, and maintain the moderate intensity physical activity as long as they have no complication related to the cancer treatment. Motivation strategies for physical activity need to be developed and applied.

• Journal of the Korean association of regional geographers
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• v.8 no.2
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• pp.170-183
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• 2002

Recently it is supposed to be a shift to regional geography. To understand the emergence of the new regional geography, It must be remarked that the progress of capitalist production and consumption change our conceptional apparatus such as representation of space. Region is one of the important mode of representations of space and time. In the Fordist capitalism of 20th century, development is regarded as diffusion of capitalist expansion of western worlds. State must support capitalist growth through regional policies which include constructing of infrastructure and regionalization of spatial division of labour. The regional development theories contributed as ideology and policy tools for state intervention. The region was simply one of the most logical classification tools of organizing geographical informations. In the theories of regional development, the concept of region was reduced to the formal unit of classification. As the transition from Fordism to flexible accumulation, the region is again acquiring its 'identity' and 'authenticity'. In this tendency of the revival of region, it is expected that good achievement could be made in the field of regional geography through relevant research methods. It is also believed one of the available means are historical approaches to the cultural and ecological regions. The historical approaches to cultural and ecological regions are not only correspondent with cultural development strategies of local governments, but also could convey regional identities through both narrativization of place and aestheticization of landscape.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.5
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• pp.225-235
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• 2018

This study was conducted to investigate the relationship among clinical nurses' emotional labor, health promoting behaviors and premenstrual syndrome (PMS), as well as to clarify factors that affect nurses' PMS. This was a descriptive study of 195 clinical nurses working in one university hospital and two general hospitals in the C region. Data collection was conducted from Jul 3 until Jul 21, 2017. T-test, ANOVA, Pearson's correlation coefficient and multiple regression were used for analysis. The mean score of emotional labor was $3.35{\pm}0.63$ out of 5, that of health promoting behavior was $2.08{\pm}0.40$ out of 4 and that of PMS was $2.94{\pm}1.09$ out of 6. Premenstrual syndrome was significantly positively correlated with emotional labor (r=0.292, p<0.001) and interpersonal relationships in health promotion behavior (r=0.208, p=0.004). Factors influencing PMS were interpersonal relationships (${\beta}=0.54$, p=0.001), emotional labor (${\beta}=0.40$, p=0.001) and degree of menstrual pain (${\beta}=0.14$, p<0.001), which explained 30.0% of PMS (F=9.33, p <0.001). The results of this study suggest that intervention strategies may be necessary to decrease PMS by reducing menstrual pain, emotional labor and interpersonal relationship stress.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.312-319
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• 2020

This study examined the factors that affect the turnover intention of newly graduated nurses. The basic data was utilized for developing a personnel resource maintenance program for newly graduated nurses. New nurses working at a general hospital in City D were surveyed from May 2016 to April 2018. The questionnaires completed by 232 volunteers were analyzed using the IBM SPSS 21.0 program, and the descriptive statistical analyses included t-tests, ANOVA, Scheffe test, Pearson's correlation coefficient, and multiple regression analysis. Among the general characteristics of new nurses, their workload displayed significant differences in proactive behavior, organizational commitment, social support, and the turnover intention. There was a negative correlation between organizational commitment, employer support, peer support, and the turnover intention. The influential factors were organizational commitment and workload, and the explanatory power for turnover intention was 36.1%. Higher organizational commitment, along with appropriate workload, led to a lower turnover intention. Therefore, appropriate work allocation through work analysis is necessary to lower the nurses' turnover intention. Developing a program that can increase proactive behavior and implementing various intervention strategies can increase the participation of newly graduated nurses when establishing and implementing appropriate hospital policies.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7045-7056
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• 2013

Since the first report of RNA interference (RNAi) less than a decade ago, this type of molecular intervention has been introduced to repress gene expression in vitro and also for in vivo studies in mammals. Understanding the mechanisms of action of synthetic small interfering RNAs (siRNAs) underlies use as therapeutic agents in the areas of cancer and viral infection. Recent studies have also promoted different theories about cell-specific targeting of siRNAs. Design and delivery strategies for successful treatment of human diseases are becomingmore established and relationships between miRNA and RNAi pathways have been revealed as virus-host cell interactions. Although both are well conserved in plants, invertebrates and mammals, there is also variabilityand a more complete understanding of differences will be needed for optimal application. RNA interference (RNAi) is rapid, cheap and selective in complex biological systems and has created new insight sin fields of cancer research, genetic disorders, virology and drug design. Our knowledge about the role of miRNAs and siRNAs pathways in virus-host cell interactions in virus infected cells is incomplete. There are different viral diseases but few antiviral drugs are available. For example, acyclovir for herpes viruses, alpha-interferon for hepatitis C and B viruses and anti-retroviral for HIV are accessible. Also cancer is obviously an important target for siRNA-based therapies, but the main problem in cancer therapy is targeting metastatic cells which spread from the original tumor. There are also other possible reservations and problems that might delay or even hinder siRNA-based therapies for the treatment of certain conditions; however, this remains the most promising approach for a wide range of diseases. Clearly, more studies must be done to allow efficient delivery and better understanding of unwanted side effects of siRNA-based therapies. In this review miRNA and RNAi biology, experimental design, anti-viral and anti-cancer effects are discussed.

• Journal of Korean Physical Therapy Science
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• v.4 no.2
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• pp.439-452
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• 1997

Mothers of handicapped children experience many problems and difficulties related to the child's prolonged dependency and demands for special care. Social support can be identified as stress-relieving factor, social support is considered to decrease the amount of negativeness in an individual or family. This study attempted to identify the level of burden and social support in mothers of children who are handicapped, and to determine whether social support is an effective strategy for burden relief in these mothers. The method used in the study was a correlational descriptive survey using a questionnaire. The subjects for the study were 42 mothers who have the handicapped children, between two to twelve years of age, being treated at S General Welfare House for Handicapped and S Rehabilitation Center in Seoul. The data were collected during 1 month from March 20 to April 20, 1996. The instruments used for this study was a structured questionnaire which was the Burden scale developed by Suh Mihae and Oh Kasil(1993) and the PRQ(Personal Resource Questionnaire) scale developed by Brandt & Weinert(1981). The collected data were analyzed using the SPSS computer program, yielding frequencies, percentiles, means, standard deviations, $x^{2}$-test, Pearson's correlation coefficienct, t-test and ANOVA. The results of this study are as follows ; 1)The range of age in the subjects was $29{\sim}44$ years, the range age in the handicapped children was $2{\sim}12$ years. 2) The mean score of burden, for the mothers of the handicapped children was 2.75(standard deviation was 0.47) of a possible total of 5. 3) The mean score of social support, for the mothers of the handicapped children was 4.99 (standard deviation was 0.59) of a possible total of 7. 4) There was an negative correlations hip between burden level and the social support, but there was no statistically significant correlationship between burden level and the social support(r = -.2252, p = .076) 5) In the general characteristics influencing on the burden level was significantly related with the sex(t = - 2.87, p = .007) and the degree of child's handicap level(F = 11.8680, p = .000l). In the general characteristics influencing on the social support was significantly related with the family(husband) support(F = 3.5199, p = .0240). There were significant differences in the mother's levels of burden depending upon the severity of child's handicap. In other words, the degree of mother's burden was directly proportionate to the degree of child's handicap level. There were significant differences in the mother's levels of social support depending upon the family(husband) support. In conclusion, on the basis of the results of this study, there was no statistically significant correlationship between burden level and the social support. Above results suggest that strategies for the intervention programs in diminishing the mother's burden and reinforcing the social support.

• The Journal of the Korea Contents Association
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• v.20 no.7
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• pp.139-148
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• 2020

This study examined the modes of access to betting games among adolescents and analyzed the influence of on-line betting games (e.g., legalized gambling, illegal gambling, speculative games) on problem gambling. The raw data from the 2018 Survey on Youth Gambling Problems were used. Using a sample of 5,101 school adolescents who were from first-grade middle school students to second-grade high school students and who experienced betting games during the last three months, this study conducted cross tabulation and logistic regression analyses. Of the adolescents who experienced betting games, 17.8% experienced on-line games that were composed of 4.9% in illegal gambling, 2.4% in speculative games, and 0.4% in legalized gambling. Compared to land-based modes of gambling, on-line illegal gambling, legalized gambling, and speculative games were associated with higher odds of problem gambling. While on-line illegal gambling was associated with higher odds of problem gambling for female adolescents, on-line illegal gambling, legalized gambling, and speculative games were associated with higher odds of problem gambling for male adolescents. This study discussed intervention strategies to address problem gambling and modes of betting games among adolescents.

• Nutrition Research and Practice
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• v.12 no.5
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• pp.387-395
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• 2018

BACKGROUND/OBJECTIVE: Recent studies showed vitamin D deficiency is linked to chronic diseases in addition to skeletal metabolism which could threaten the elderly. We analyzed health conditions and socio-demographic factors associated with vitamin D deficiency in community dwelling people aged 65 years and older. SUBJECTS/METHOD: Data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010 to 2012 were obtained. A total of 2,687 subjects aged 65 years and older were participated. The cutoff value of the Vitamin D deficiency was considered as serum 25-hydroxyvitamin D [25(OH)D] ${\leq}20ng/mL$ (50 nmol/L). RESULTS: The overall prevalence rate of vitamin D deficiency in the elderly was 62.1%. The factors such as female, obesity, metabolic syndrome, current smoker, and skipping breakfast were positively associated with vitamin D deficiency, but high intensity of physical activity and more than 9 hours of sleep duration were negatively associated with vitamin D deficiency (all P < 0.05). CONCLUSIONS: It is important that health professions know that the factors proved in this study are connected to vitamin D deficiency thus provide information and intervention strategies of vitamin D deficiency to old aged people.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.3
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• pp.485-492
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• 2017

This study was conducted to identify the preservice teacher's health perception and health promoting behavior, and attitudes towards children with asthma, as well as to examine the relationship between these variables and the influencing factors. The participants were 329 third and fourth grade students from the national university of education in G city. The data were analyzed using Pearson correlation coefficients, t-test, ANOVA, Scheffe test, and multiple regression with SPSS/WIN 23.0. The score for the participants' health perception was 2.85 out of a possible 4, health promoting behavior about 2.49 out of a possible 4, and their score for attitude towards asthma was 3.67 points of a possible 5. The health perception and health promoting behavior showed a positive correlation with the attitudes about child with asthma. Interpersonal relations and health perception and grade had a significant influence on the attitudes about child with asthma. These variables accounted for 12.2% of the attitudes about child with asthma. The results highlight the need for intervention strategies to enhance the health promoting behavior and health perception.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.11
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• pp.4699-4704
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• 2015

Medical diagnostic X-ray workers are one occupational group that expose to the long-term low-dose external radiation over their working lifetime, and they may under risk of different cancers. This study aims to determine the relationship between the occupational X-ray radiation exposure and cancer risk among these workers in Jiangsu, China. We conducted Nested case-control study to investigate the occupational X-ray radiation exposure and cancer risk. Data were collected through self-administered questionnaire, which includes but not limits to demographic data, personal behaviors and family history of cancer. Retrospective dose reconstruction was conducted to estimate the cumulative doses of the x-ray workers. Inferential statistics, t-test and 2 tests were used to compare the differences between each group. We used the logistic regression model to calculate the odds ratio (OR) and 95% confidence interval (CI) of cancer by adjusting the age, gender. All 34 breast cancer cases and 45 esophageal cancer cases that detected in a cohort conducted among health workers between 1950~2011 were included in this presented study, and 158 cancer-free controls were selected by frequency-matched (1:2). Our study found that the occupational radiation exposure was associated with a significantly increased cancer risk compared with the control, especially in breast cancer and esophageal cancer (adjusted OR=2.90, 95% CI: 1.19-7.04 for breast cancer; OR=4.19, 95% CI: 1.87-9.38 for esophageal cancer, and OR=3.43, 95% CI: 1.92-6.12 for total cancer, respectively). The occupational X-ray radiation exposure was associated with increasing cancer risk, which indicates that proper intervention and prevention strategies may be needed in order to bring down the occupational cancer risk.