• 대한통합의학회지
• /
• 제9권4호
• /
• pp.105-117
• /
• 2021

Purpose : This study examined the effect of transcranial direct current stimulation (tDCS) combined high intensity interval training (HIIT) on the aerobic exercise capacity of college soccer players. Methods : The subjects of this study were 30 college soccer players. They were divided into a high intensity interval training group combining transcranial direct current stimulation (Group I) and a high intensity interval training group (Group II). Each group had 15 subjects randomly assigned. After receiving general soccer training, each group additionally received high intensity interval training combined with transcranial direct current stimulation and high intensity interval training for 30 minutes 5 times a week for 8 weeks. Their VO₂max and 20 meter shuttle run test, Yo-Yo intermittent recovery test were analyzed before the intervention. After 8 weeks of intervention, the above items were re-measured and an intergroup analysis was performed. Results : As a result of comparative analysis of VO₂max intake between groups, 20 meter shuttle run test and Yo-Yo intermittent recovery test, a statistically significant difference was found. The high intensity interval training group (Group I) combined with transcranial direct current stimulation showed a significant difference in aerobic exercise capacity compared to the high intensity interval training group (Group II). Conclusion : These results showed that high intensity interval training group combined with transcranial direct current stimulation was more effective for aerobic exercise. Based on this study, this study proposes an effective program for patients as well as elite athletes. In the future, it is necessary to develop an effective transcranial direct current stimulation program and to study how to apply it for various patients.

• 운동과학
• /
• 제26권3호
• /
• pp.223-228
• /
• 2017

PURPOSE: This study investigated the protective role of high-intensity interval training against acute liver injury induced by D-galactosamine (D-Gal)/lipopolysaccharide (LPS). METHODS: A total of 30 male BALB/c mice aged 5-week were randomly assigned to high-intensity, interval training group (EX, n=10) or control group in cage (Non-EX, n=20) for 10 weeks. Peritoneal injection of D-Gal (700 mg/kg body weight) and LPS ($10{\mu}g/kg$ body weight) was applied to induce acute liver injury, and liver tissue was harvested 6 hours after the injection. Hematoxylin and Eosin (H&E) staining was used for liver histology. Real-time PCR was used to quantify expression of pro-inflammatory and anti-inflammatory genes in the liver. RESULTS: The liver histology showed that D-Gal/LPS treatment resulted in hepatic damage and increased number of neutrophils in conjunction with upregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and downregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. On the other hand, the 10-week interval training resulted in a significant improvement in cardiorespiratory fitness assessed as run time to exhaustion on a treadmill. In addition, the interval training attenuated the D-Gal/LPS-induced liver damage and increased number of neutrophil in conjunction with downregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and upregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. CONCLUSIONS: This study suggests that high-intensity interval training suppresses the D-Gal and LPS-induced acute liver damage and inflammatory responses.

• 한국컴퓨터정보학회논문지
• /
• 제25권11호
• /
• pp.187-193
• /
• 2020

본 연구는 강도가 다른 인터벌 트레이닝이 체지방량, 유연성, 순발력, 민첩성, 그리고 최대산소 섭취량에 대한 효과에 대해 알아보고자 하였다. 총 30명의 젊은 남성들이 자발적으로 이 연구에 참여했다. 대상자들은 중등도 유산소 운동군과 고강도 인터벌트레이닝군에 무작위로 배분하였다. 운동프로그램은 6주동안 진행하였으며, 각 세션은 주 4회에 50분씩 진행하였다. 고강도 인터벌 트레이닝 군에서 체지방률, 유연성, 순발력, 민첩성 및 최대산소섭취량에서 유의한 차이를 보였고(p<.05), 중등도 유산소 운동은 체지방률, 유연성 및 최대산소섭취량에서 유의한 차이가 나타났다(p<.05). 두 군간의 비교에서는 체지방률, 유연성, 순발력, 민첩성에서 유의한 차이가 나타났다(p<.05). 그러므로 고강도 인터벌 트레이닝은 근골격계의 능력과 순발력에서 젋은 비만 남성에게 큰 도움이 될 것이다.

• 생물정신의학
• /
• 제4권2호
• /
• pp.237-245
• /
• 1997

The study was designed to evaluate the significant roles of SSRI in rat of depression model. Chronic exposure to mild unpredictable stress has been found to depress the consumption of sweet 1% sucrose solutions in the Sprague-Dawley rats. We applied the variety of 11 types of stress regimens and identified depressive behaviours(developed by Willner) in 70 Sprague-Dawley rats. Rats in experiments were stratified into 6 groups, ie ; 3 kinds of SSRI(paroxetine, fluoxetine, sertraline), clomipramine, choline and saline control. Memory function was evaluated by passive avoidance learning and retention test. The authors determined how long memory retention would remain improved with 24 hour, 1 week, 2 weeks, 3 weeks, and 4 weeks at training-testing interval in depressive states of the Sprague-Dawley rats. The results were as follows ; 1) There were no significant differences between the 6 groups at the 24 hour training-testing interval. 2) The paroxetine treated group showed significant differences from the control group at the 1 week and 2 weeks training-testing interval. 3) The paroxetine and the fluoxetine treated groups showed singificant differences from the control group at 3 week training-testing interval. 4) The paroxetine and the choline treated groups showed significant differences from the control group at 4 week training-testing interval. In summary, paroxetine had an effect on long term memory processing from 1st week to 4th week. Also, fluoxetine(at 3rd week) and choline(at 4th week) had effect on long term memory processing. Sertraline, clomipramine were ineffective on memory processing during 4 weeks observation. Possible explanations why paroxetine had early effect on memory processing than the other selective serotonin reuptake inhibitors are rapid bioavailability, which is the characteristics of pharmacokinetics of paroxetine. In clinical situation, author carefully suggest that SSRI would be beneficial to improve the memory function caused by depressive neurochemical changes.

• 대한물리의학회지
• /
• 제15권1호
• /
• pp.43-54
• /
• 2020

PURPOSE: This study examined the effects of mild-intensity exercise (MIE) and high-intensity interval exercise (HIIE) on the recovery of the motor function over time in sciatic nerve crush injury rats. METHODS: The MIE group ran on a treadmill at a speed of 8.3 m/min to perform low-intensity training with maximum oxygen uptakes ranging from 40 to 50%. The HIIE group ran on the treadmill at a speed of 25 m/min to perform high-intensity training with a maximum oxygen uptake of 80%. The interval training was performed based on a 1:1 work-to-rest ratio. The effects of each form of exercise on the rats' walking abilities following their recovery from the peripheral nerve injuries were evaluated based on the results of behavior tests performed at one and 14 days. RESULTS: According to the test results, the MIE group showed significant improvements in the rats' ankle angle in the initial stance phase, and in the ankle and knee angles in the toe-off phase (p<.05). The HIIE group exhibited significant improvements in the ankle and knee angles in the initial stance phase, SFI(p<.05). CONCLUSION: The state of such patients can be improved by applying the results of this study in that MIE and HIIE on a treadmill can contribute to the recovery of the peripheral nerve and motor skill. In particular, MIE is used as a walking functional training in the toe-off stance phase, while HIIE is suitable in the initial stance stage.

• 한국통신학회논문지
• /
• 제21권8호
• /
• pp.2119-2132
• /
• 1996

본 연구에서는 구간 벡터의 비선형 사상의 근사를 행하기 위한 4가지 신경회로망의 학습 알고리즘을 제안한다. 제안된 방법에 있어서, 신경회로망의 학습에 이용되는 입출력 데이터 쌓은 구간으로 구성되어 있다. 첫번째 방법은 전처리된 학습용 데이터 상을 통상의 역전파 알고리즘에 직접 응용하는 것이고, 두번째 방법은 두 개의 역전파 알고리즘을 이용하는 것이다. 세번째 방법은 구간 입출력 데이터를 처리할 수 있는 역전파 알고리즘으로 확장한 것이다. 마지막 방법은 구간 결합강도 및 구간 역치를 가진 신경회로망으로 확장한 것이다. 제안된 이 방법들은 컴퓨터 시뮬레이션에 의해 서로 비교 평가된다.

• 생명과학회지
• /
• 제26권1호
• /
• pp.129-139
• /
• 2016

운동은 중추와 말초의 각종 성장인자(BDNF, IGF-1, VEGF)들의 상호작용에 의해 뇌신경가소성을 증진시키고 인지기능을 향상시킨다. 지금까지 저·중강도 지속성 유산소 운동의 효과를 검증하는 선행연구가 주로 이루어졌기 때문에 고강도 운동에 따른 뇌신경성장인자의 발현 및 인지기능 개선 효과에 대한 연구는 미흡한 실정이다. 하지만 최근의 과학적 증거들은 고강도 인터벌 운동이 시간 효율성, 안전성, 심폐지구력 개선 및 체중 감소에 효과적임을 암시하고 있으며, 미스포츠의학회(ACSM)에서 권장하는 일반인을 위한 운동지침에서도 무리가 되지 않는 수준에서 고강도 인터벌 운동 수행을 강조하고 있다. 특히 최근에 발표된 선행 연구에서 고강도 인터벌 운동은 말초조직과 뇌에서의 BDNF, IGF-1, VEGF의 발현을 증가시키고 그로 인한 인지기능 발달에 기여한다는 것을 보고하였으며, 관련된 유력한 생리학적 기전으로 고강도 인터벌 운동으로 인한 뇌의 저산소화와 뇌신경대사의 부가적인 에너지원이 될 수 있는 젖산 이용성 증가가 대두되고 있다. 따라서 향후 저산소화 및 젖산 이용성 증가에 따른 뇌신경성장인자 발현 개선에 어떤 분자생물학적 기전이 관여하는지를 탐구할 필요가 있으며, 또한 동일한 운동량을 가진 저·중강도 지속성 유산소 운동과의 비교 연구를 통해 뇌신경성장인자의 발현 및 인지기능 개선에 있어 고강도 인터벌 운동의 우수성을 입증하는 연구가 요구된다.

• Journal of applied mathematics & informatics
• /
• 제35권1_2호
• /
• pp.95-111
• /
• 2017

Recently, interval-valued fuzzy graph is a growing research topic as it is the generalization of fuzzy graphs. The interval-valued fuzzy graphs are more flexible and compatible than fuzzy graphs due to the fact that they allowed the degree of membership of a vertex to an edge to be represented by interval values in [0.1] rather than the crisp values between 0 and 1. In this paper, we introduce the concepts of regular and totally regular interval-valued fuzzy graphs and discusses some properties of the ${\mu}$-complement of interval-valued fuzzy graph. Self ${\mu}$-complementary interval-valued fuzzy graphs and self-weak ${\mu}$-complementary interval-valued fuzzy graphs are defined and a necessary condition for an interval valued fuzzy graph to be self ${\mu}$-complementary is discussed. We define busy vertices and free vertices in interval valued fuzzy graph and study their image under an isomorphism.

• The Journal of Korean Physical Therapy
• /
• 제15권4호
• /
• pp.255-298
• /
• 2003

The purpose of study was to evaluate effects of a trunk muscle strength training on sitting balance of children with spastic cerebral palsy. Five individuals with spastic cerebral palsy(three females. two males; mean aged 6.6) participated three times a week over 6 weeks. Five individuals with spastic cerebral palsy(three females. two males; mean aged 7.0) who did not receive strength training served as control. BPM(Balance Performance Moniter) was used to measured sitting balance and EMG(electromyograph, NORAXON, USA) was used to measured activities of abdominal and erector spine muscle. The obtain result are as follows. 1. The result of this study were following that maximum perturbation area and perturbation velocity were significantly reduced strength training group compared with control group(p<.05). 2. The result of this study were following that maximum perturbation area and perturbation velocity were significantly reduced after strength training compared with pre strength training in strength training group(p<.05). 3. The result of this study were following that maximum perturbation area and perturbation velocity were not significantly reduced at interval of six week in control group(p<.05). 4. The result of this study were following that abdominal muscle activity was significantly increased strength training group compared with control group(p<.05). 5. The result of this study were following that erector spine muscle activity was significantly increased strength training group compared with control group(p<.05). 6. The result of this study were following that abdominal muscle activity and erector spine muscle were significantly increased after strength training compared with pre strength training in strength training group(p<.05). 7. The result of this study were following that abdominal muscle activity and erector spine muscle were not significantly increased at interval of six week in control group(p<.05). In conclusion, the result of this study suggest that improved sitting balance and increased activities of trunk muscle by trunk strength training in spastic cerebral palsy. The result was proposed that therapeutic approach of spastic cerebral palsy with impaired sitting balance should use trunk strength training.

• 한국체육학회지인문사회과학편
• /
• 제51권5호
• /
• pp.639-647
• /
• 2012

본 연구는 최근 3개월 동안 저항운동 경력이 없는 남학생 14명을 선정하여 2주간 체력을 안정화 시킨 후, 운동 강도(90, 75, 60% 1RM)와 세트 간 휴식시간(1, 3, 5분)을 조합한 9가지 운동 프로그램을 1주일 간격으로 적용하였다. 근기능 지표들(근수축력, 반복횟수, 총운동량)의 변화를 분석함으로써 적절한 운동 강도와 휴식시간의 효용성을 분석한 결과는 다음과 같다. 운동 강도별 세트 간 휴식시간에 따른 대흉근의 근수축력은 90, 60% 1RM 강도에서 유의하게 감소하였으나, 60% 1RM 강도에서 세트 간 5분 휴식 시에는 유의하게 증가하는 것으로 나타났고, 상완삼두근의 근수축력은 90% 1RM에서 세트 간 휴식시간에 따라 유의하게 감소하는 것으로 나타났다. 반복횟수와 총운동량은 세트 간 휴식시간에 따라 모든 강도에서 유의하게 감소하였으나, 강도가 낮아지고 휴식시간이 길어질수록 유의하게 증가하는 것으로 나타났다. 이상의 결과를 종합하면, 처음 저항운동을 시작하는 사람이나 비단련자의 경우에는 근기능 향상 및 정확한 자세와 기술을 습득할 수 있도록 운동 강도를 낮추거나 휴식시간을 길게 유지하는 방법이 효과적일 것이다.