• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.105-117
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• 2021

Purpose : This study examined the effect of transcranial direct current stimulation (tDCS) combined high intensity interval training (HIIT) on the aerobic exercise capacity of college soccer players. Methods : The subjects of this study were 30 college soccer players. They were divided into a high intensity interval training group combining transcranial direct current stimulation (Group I) and a high intensity interval training group (Group II). Each group had 15 subjects randomly assigned. After receiving general soccer training, each group additionally received high intensity interval training combined with transcranial direct current stimulation and high intensity interval training for 30 minutes 5 times a week for 8 weeks. Their VO₂max and 20 meter shuttle run test, Yo-Yo intermittent recovery test were analyzed before the intervention. After 8 weeks of intervention, the above items were re-measured and an intergroup analysis was performed. Results : As a result of comparative analysis of VO₂max intake between groups, 20 meter shuttle run test and Yo-Yo intermittent recovery test, a statistically significant difference was found. The high intensity interval training group (Group I) combined with transcranial direct current stimulation showed a significant difference in aerobic exercise capacity compared to the high intensity interval training group (Group II). Conclusion : These results showed that high intensity interval training group combined with transcranial direct current stimulation was more effective for aerobic exercise. Based on this study, this study proposes an effective program for patients as well as elite athletes. In the future, it is necessary to develop an effective transcranial direct current stimulation program and to study how to apply it for various patients.

• Exercise Science
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• v.26 no.3
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• pp.223-228
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• 2017

PURPOSE: This study investigated the protective role of high-intensity interval training against acute liver injury induced by D-galactosamine (D-Gal)/lipopolysaccharide (LPS). METHODS: A total of 30 male BALB/c mice aged 5-week were randomly assigned to high-intensity, interval training group (EX, n=10) or control group in cage (Non-EX, n=20) for 10 weeks. Peritoneal injection of D-Gal (700 mg/kg body weight) and LPS ($10{\mu}g/kg$ body weight) was applied to induce acute liver injury, and liver tissue was harvested 6 hours after the injection. Hematoxylin and Eosin (H&E) staining was used for liver histology. Real-time PCR was used to quantify expression of pro-inflammatory and anti-inflammatory genes in the liver. RESULTS: The liver histology showed that D-Gal/LPS treatment resulted in hepatic damage and increased number of neutrophils in conjunction with upregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and downregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. On the other hand, the 10-week interval training resulted in a significant improvement in cardiorespiratory fitness assessed as run time to exhaustion on a treadmill. In addition, the interval training attenuated the D-Gal/LPS-induced liver damage and increased number of neutrophil in conjunction with downregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and upregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. CONCLUSIONS: This study suggests that high-intensity interval training suppresses the D-Gal and LPS-induced acute liver damage and inflammatory responses.

• Journal of the Korea Society of Computer and Information
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• v.25 no.11
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• pp.187-193
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• 2020

This study is proposed to the effects of interval training by different intensity on body fat, flexibility, agility, quickness, and maximal oxygen consumption. A total of 30 healthy men voluntarily participated in the study. The participants were randomized to moderate aerobic exercise(n=15) and high-intensity interval training groups(n=15). Exercise programs lasted for six weeks, with each session occurring four times per week for 50 minutes per session. There were significant differences in fat and physical fitness according to flexibility, agility, quickness, and maximal oxygen consumption within the high-intensity interval training groups(p<.05). For the moderate aerobic exercise group, there was a significant difference in fat, flexibility, maximal oxygen consumption(p<.05). There were significant differences between groups for fat, flexibility, agility and quickness(p<.05). Therefore using high-intensity interval training will significantly benefit obese young men in musculoskeletal capacity and quickness.

• Korean Journal of Biological Psychiatry
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• v.4 no.2
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• pp.237-245
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• 1997

The study was designed to evaluate the significant roles of SSRI in rat of depression model. Chronic exposure to mild unpredictable stress has been found to depress the consumption of sweet 1% sucrose solutions in the Sprague-Dawley rats. We applied the variety of 11 types of stress regimens and identified depressive behaviours(developed by Willner) in 70 Sprague-Dawley rats. Rats in experiments were stratified into 6 groups, ie ; 3 kinds of SSRI(paroxetine, fluoxetine, sertraline), clomipramine, choline and saline control. Memory function was evaluated by passive avoidance learning and retention test. The authors determined how long memory retention would remain improved with 24 hour, 1 week, 2 weeks, 3 weeks, and 4 weeks at training-testing interval in depressive states of the Sprague-Dawley rats. The results were as follows ; 1) There were no significant differences between the 6 groups at the 24 hour training-testing interval. 2) The paroxetine treated group showed significant differences from the control group at the 1 week and 2 weeks training-testing interval. 3) The paroxetine and the fluoxetine treated groups showed singificant differences from the control group at 3 week training-testing interval. 4) The paroxetine and the choline treated groups showed significant differences from the control group at 4 week training-testing interval. In summary, paroxetine had an effect on long term memory processing from 1st week to 4th week. Also, fluoxetine(at 3rd week) and choline(at 4th week) had effect on long term memory processing. Sertraline, clomipramine were ineffective on memory processing during 4 weeks observation. Possible explanations why paroxetine had early effect on memory processing than the other selective serotonin reuptake inhibitors are rapid bioavailability, which is the characteristics of pharmacokinetics of paroxetine. In clinical situation, author carefully suggest that SSRI would be beneficial to improve the memory function caused by depressive neurochemical changes.

• Journal of the Korean Society of Physical Medicine
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• v.15 no.1
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• pp.43-54
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• 2020

PURPOSE: This study examined the effects of mild-intensity exercise (MIE) and high-intensity interval exercise (HIIE) on the recovery of the motor function over time in sciatic nerve crush injury rats. METHODS: The MIE group ran on a treadmill at a speed of 8.3 m/min to perform low-intensity training with maximum oxygen uptakes ranging from 40 to 50%. The HIIE group ran on the treadmill at a speed of 25 m/min to perform high-intensity training with a maximum oxygen uptake of 80%. The interval training was performed based on a 1:1 work-to-rest ratio. The effects of each form of exercise on the rats' walking abilities following their recovery from the peripheral nerve injuries were evaluated based on the results of behavior tests performed at one and 14 days. RESULTS: According to the test results, the MIE group showed significant improvements in the rats' ankle angle in the initial stance phase, and in the ankle and knee angles in the toe-off phase (p<.05). The HIIE group exhibited significant improvements in the ankle and knee angles in the initial stance phase, SFI(p<.05). CONCLUSION: The state of such patients can be improved by applying the results of this study in that MIE and HIIE on a treadmill can contribute to the recovery of the peripheral nerve and motor skill. In particular, MIE is used as a walking functional training in the toe-off stance phase, while HIIE is suitable in the initial stance stage.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.8
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• pp.2119-2132
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• 1996

This paper proposes four approaches for approximately realizing nonlinear mappling of interval vectors by neural networks. In the proposed approaches, training data for the learning of neural networks are the paris of interval input vectors and interval target output vectors. The first approach is a direct application of the standard BP (Back-Propagation) algorithm with a pre-processed training data. The second approach is an application of the two BP algorithms. The third approach is an extension of the BP algorithm to the case of interval input-output data. The last approach is an extension of the third approach to neural network with interval weights and interval biases. These approaches are compared with one another by computer simulations.

• Journal of Life Science
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• v.26 no.1
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• pp.129-139
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• 2016

Exercise increases the expression and interaction of major neurotrophic factors such as brain-derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1), and vascular endothelial growth factor (VEGF) at both central and peripheral tissues, which contributes to improved brain and neural plasticity and cognitive function. Previous findings have been to understand the effect of light or moderate intensity aerobic exercise on neurotrophic factors and cognitive function, not that of high intensity aerobic exercise. However, recent findings suggest that high intensity interval training is a safe, less time-consuming, efficient way to improve cardiorespiratory fitness and weight control, thus American College of Sport Medicine (ACSM)’s guidelines for exercise prescription for various adult populations also recommend the application of high intensity interval training to promote their overall health. High intensity interval training also enhances the expression of BDNF, IGF-1, and VEGF at the brain and peripheral tissues, which improves cognitive function. Increased frequency of intermittent hypoxia and increased usage of lactate as a supplementary metabolic resource at the brain and neural components are considered a putative physiological mechanism by which high intensity interval training improves neurotrophic factors and cognitive function. Therefore, future studies are required to understand how increased hypoxia and lactate usage leads to the improvement of neurotrophic factors and what the related biological mechanisms are. In addition, by comparing with the iso-caloric moderate continuous exercise, the superiority of high intensity interval training on the expression of neurotrophic factors and cognitive function should be demonstrated by associated future studies.

• Journal of applied mathematics & informatics
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• v.35 no.1_2
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• pp.95-111
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• 2017

Recently, interval-valued fuzzy graph is a growing research topic as it is the generalization of fuzzy graphs. The interval-valued fuzzy graphs are more flexible and compatible than fuzzy graphs due to the fact that they allowed the degree of membership of a vertex to an edge to be represented by interval values in [0.1] rather than the crisp values between 0 and 1. In this paper, we introduce the concepts of regular and totally regular interval-valued fuzzy graphs and discusses some properties of the ${\mu}$-complement of interval-valued fuzzy graph. Self ${\mu}$-complementary interval-valued fuzzy graphs and self-weak ${\mu}$-complementary interval-valued fuzzy graphs are defined and a necessary condition for an interval valued fuzzy graph to be self ${\mu}$-complementary is discussed. We define busy vertices and free vertices in interval valued fuzzy graph and study their image under an isomorphism.

• The Journal of Korean Physical Therapy
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• v.15 no.4
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• pp.255-298
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• 2003

The purpose of study was to evaluate effects of a trunk muscle strength training on sitting balance of children with spastic cerebral palsy. Five individuals with spastic cerebral palsy(three females. two males; mean aged 6.6) participated three times a week over 6 weeks. Five individuals with spastic cerebral palsy(three females. two males; mean aged 7.0) who did not receive strength training served as control. BPM(Balance Performance Moniter) was used to measured sitting balance and EMG(electromyograph, NORAXON, USA) was used to measured activities of abdominal and erector spine muscle. The obtain result are as follows. 1. The result of this study were following that maximum perturbation area and perturbation velocity were significantly reduced strength training group compared with control group(p<.05). 2. The result of this study were following that maximum perturbation area and perturbation velocity were significantly reduced after strength training compared with pre strength training in strength training group(p<.05). 3. The result of this study were following that maximum perturbation area and perturbation velocity were not significantly reduced at interval of six week in control group(p<.05). 4. The result of this study were following that abdominal muscle activity was significantly increased strength training group compared with control group(p<.05). 5. The result of this study were following that erector spine muscle activity was significantly increased strength training group compared with control group(p<.05). 6. The result of this study were following that abdominal muscle activity and erector spine muscle were significantly increased after strength training compared with pre strength training in strength training group(p<.05). 7. The result of this study were following that abdominal muscle activity and erector spine muscle were not significantly increased at interval of six week in control group(p<.05). In conclusion, the result of this study suggest that improved sitting balance and increased activities of trunk muscle by trunk strength training in spastic cerebral palsy. The result was proposed that therapeutic approach of spastic cerebral palsy with impaired sitting balance should use trunk strength training.

• 한국체육학회지인문사회과학편
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• v.51 no.5
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• pp.639-647
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• 2012

The purpose of this study was to examine the effects of varied resistance training intensities and rest intervals between training sets on integral electromyography (iEMG), repetition rate, and total work. All subjects, 14 college students, were tested one repetition maximum (1RM). Then, all subjects were weekly tested with 9 practice procedures, composed of diverse intensities (60, 75, 90% of 1RM) and rest intervals (1, 3, 5 min). As results show, to maintain the same load and target repetition maximum for an untrained person, muscular power training (90% of 1RM), muscular hypertrophy training (75% of 1RM), and muscular endurance training (60% of 1RM) should be applied with 5 min or longer rest interval periods for 3 training sets. In addition, 2 training sets with 3 min rest intervals and a set with an 1 min rest interval were capable by the subjects. Thus, at least 3 min or longer rest intervals should be applied to maintain multiple training sets. In case for muscular endurance training, which requires shorter rest intervals, the intensity of exercise should be adjusted to 60% of 1RM or less. In conclusion, depending on diverse purposes of resistance training such as improving muscular power, muscular hypertrophy, or muscular endurance, appropriate exercise intensity and rest intervals should be applied.